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Name of Drug Classification and Indication and Side Effects or Adverse Nursing Responsibilities

(Dosage, Route, Frequency, Mechanism of Action Contraindication Reactions


Timing)
14 rights of medication
Generic Name: Classification: Belongs to Indication: Dizziness, headache,
the class of platelet Intermittent claudication palpitations, diarrhoea, 1. Right Drug/Medication
Cilostazol aggregation inhibitors nausea, vomiting, oedema, 2. Right Client/Patient
excluding heparin. Used in cardiac arrhythmias, chest 3. Right Route
Brand Name: the treatment of thrombosis. pain, rhinitis, ecchymosis, 4. Right Dose
Contraindication: rash, haemorrhage. Rarely, 5. Right Frequency/Time
Pletal CHF of any severity, QT haematological 6. Right Assessment
Mechanism of Action: interval prolongation, 7. Right Approach
abnormalities including
Description: Cilostazol predisposition to bleeding 8. Right Education
agranulocytosis,
Dosage: inhibits phosphodiesterase-III (e.g. active peptic ulceration, 9. Right Evaluation
leucopoenia, 10. Right Documentation
(PDE-III), thereby suppressing proliferative diabetic thrombocytopenia.
45 mg 1 tab 11. Right to Refuse
cyclic adenosine retinopathy, recent Potentially 12. Right Principle of Care
monophosphate (cAMP) haemorrhagic stroke [w/in 6 Fatal: Pancytopenia, aplastic
Route: 13. Right Prescription
degradation. Increase in mth], poorly controlled HTN); anaemia. 14. Right Nurse Clinician
cAMP in platelets and blood unstable angina pectoris, MI
Oral
vessels leads to inhibition of or coronary intervention w/in
platelet aggregation, the last 6 mth.
Frequency:
vasodilation and inhibition of
OD vascular smooth muscle cell
proliferation.
Timing: Onset: Effect on walking
distance: 2-4 wk; may require
12pm up to 12 wk.
Pharmacokinetics:
Absorption: Absorbed from
the GI tract. Increased
absorption if taken w/ a high
fat meal.
Distribution: Plasma protein
binding: 95-98%.

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