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TREATMENT
Surgical Therapy
The following table summarizes the most common surgical options according to dimensions,
extension, and localization of the defect. [15, 16, 17]
Table 3. Surgical Options for Foot Reconstruction (Open Table in a new window)
Weightbearing
< 3 cm2 Soft tissue Local flap
areas
Nonweightbearing
< 3 cm2 Soft tissue Skin grafts
areas
Soft tissue
Weightbearing
>3 cm2 and bone Free osteocutaneous flap
areas
loss
Local Flaps
Sole
See the list below:
A study by Struckmann et al indicated that both free and pedicled flaps are equally suitable for the
reconstruction of plantar tissue defects. The study, in which 12 free flaps and nine pedicled flaps were
used, found that the two flap types yielded essentially the same functional results. [18]
Dorsum
Medial side
Lateral side
Lateral calcaneal artery skin flap, described by Grabb and Argenta (1981).
Sural flap; perforator flap from peroneal artery; described by Donski and Fogdestam, 1983.
Perforator
Cutaneous
Fasciocutaneous
Muscular
Preoperative Details
Consider etiology of the defect, age of the patient, concomitant diseases, concomitant leg fracture,
and working activity.
In free flaps, the choice of the recipient vessels depends on the vascular condition of the foot and leg.
Intraoperative Details
In patients with limited defects, position the patient supine or prone according to the location of
the defect.
For major surgical treatment, position the patient according to both the location of the defect
and the type of reconstruction to allow simultaneous flap harvest and preparation of the
recipient area.
Extend the debridement of the defect to vital tissues.
Check the actual size of the loss after the debridement.
With free flaps, verify the condition of the recipient vessels under magnification.
The harvest of the flap can be performed under tourniquet with osteocutaneous flaps such as
the fibula.
Raise the flap and transfer it to fill the gap.
Use drains whenever necessary.
Close the donor area according to the surgeon's preference.
Postoperative Details
Position the patient, possibly on an air or water mattress, with both legs slightly elevated.
Monitor the viability of the flap in the early postoperative period according to the reconstructive
procedure.
For free flaps, monitor every 2 hours in the first 2 days and 4 times per day until 2 weeks
postoperatively with the aid of a Doppler probe to check the patency of the microanastomosis
and to survey the skin or muscle island.
Follow-up
Observe contour and stability of the reconstruction after 2 weeks and 1, 3, 6, and 12 months
postoperatively.
In patients with defects of the sole, load and walking ability generally are recovered in 1 month.
In patients who underwent primary bone reconstruction, load and walking ability are delayed
until bone union is achieved, as evaluated with serial radiographs or bone scans.
Custom-made shoes can be recommended for 3-6 months.
Complications
Complications may be divided into general and specific, and specific complications can be
related to the recipient or to the donor area.
Generic complications are those related to each surgical procedure (eg, reaction to anesthetics,
hematoma, seroma, infection).
Specific complications include partial loss of the flap (eg, de-epithelialization of the flap,
occasional minor breakdowns of the flap, malunion).
In free flap transfers, complications may be divided into 2 groups: complications of the donor
area and complications of the recipient area.
Donor area complications include hematoma, seroma, skin graft loss, and wound dehiscence.
Recipient area complications include partial or total loss of the flap.
Early complications mainly are related to vascular problems such as venous or arterious
thrombosis and may require a re-exploration of the anastomosis.
Late complications are infections and pressure sores due to early recovery under the 100% load.
(Click here to complete a Medscape CE activity about pressure ulcers.)
A retrospective study by Cho et al indicated that diabetes, chronic ulceration, an elevated platelet
count, and an abnormal angiogram increase the risk of reconstruction failure in patients undergoing
foot and ankle free tissue transfer. The study involved 231 free flap procedures (in 225 patients) for
foot and ankle reconstruction, with the investigators identifying chronic ulceration and an elevated
preoperative platelet count as independent risk factors for postoperative foot ischemia (ie, ischemia-
related tissue necrosis not occurring at the reconstruction site), and diabetes and an abnormal
preoperative angiogram as predictors of flap failure. [25]
A study by Sato et al suggested that the use of free flaps in the reconstruction of extensive tissue
defects from diabetic foot ulcers may increase patients’ chances of achieving independent
ambulation. The investigators found that of 23 patients who underwent free flap reconstruction for
diabetic foot ulcers (using free rectus abdominis, latissimus dorsi, or anterolateral thigh flaps), 16
experienced successful surgery, with 12 of these individuals attaining independent ambulation. [26]
Other considerations
The treatment of foot ulcers is often difficult, with a relatively high incidence of recurrence, especially
in older patients with vascular or dysmetabolic diseases.
Always consider the general condition of the patient in advance to plan the most correct treatment of
the local defect. The prognosis is strictly dependent on the age of the patient and the etiology of the
defect.
From a surgical point of view, flaps usually give a better result than grafts, with a low rate of
breakdowns or recurrence. However, grafts can be remarkably durable on weightbearing (WB) areas
and may be the first choice in certain situations.
Even if grafts are advisable in some patients, local flaps provide the most similar tissue and must be
the first choice when the defect is not less than 3 cm wide.
The advent of microsurgery and the use of free flaps have changed the approach for the treatment of
large defects.
Fasciocutaneous flaps for pure soft tissue loss are versatile and usually offer a suitable paddle of
tissue to reconstruct either WB or nonweightbearing (NWB) areas. Surgical recovery is fast, and the
patient can wear normal shoes early on.
Muscular or myocutaneous flaps must be necessary in large avulsions with bone infection. Surgical
recovery with these flaps can be slightly longer, especially because of their thickness, which prohibits
the use of normal shoes.
Myocutaneous flaps, particularly bulky in the beginning, usually reduce their thickness in 6 months
because of the process of atrophy of the denervated muscle.
Finally, osteocutaneous flaps truly represent the option to avoid amputation, restoring not only the
loss of tissue but especially the function of the foot in the gait.
The future of this field will be influenced by new technologies and cellular cultures, with the possibility
of reproducing any type of tissue in the laboratory.