DRUG INDICATION CONTRAINDICATON SIDE EFFECT NURSING CONSIDERATION
Oxacillin
Bactocill, Infections due to  Contraindications:  CNS: Lethargy,
ProstaphilinPregnancy penicillinase- allergies to penicillins, hallucinations, seizures
Category B producing cephalosporins, or  GI: Glossitis, stomatitis,
staphylococci other allergens. gastritis, sore mouth,
 Use cautiously with furry tongue, black
Drug classes renal disorders, "hairy" tongue, nausea,
pregnancy, lactation vomiting, diarrhea,
 Antibiotic (may cause diarrhea abdominal pain, bloody
 Penicillinase- or candidiasis in diarrhea, enterocolitis,
resistant penicillin infants). pseudomembranous
colitis, nonspecific
hepatitis
 Hematologic: Anemia,
thrombocytopenia,
leukopenia,
neutropenia, prolonged
bleeding time (more
common than with
other penicillinase-
resistant penicillins)
 GU: Nephritis--oliguria,
proteinuria, hematuria,
casts, azotemia, pyuria
 Hypersensitivity: Rash,
fever,
wheezing, anaphylaxi
s Water for Injection or
 Local: Pain, phlebitis,
thrombosis at injection
site
 Other: Superinfections,
sodium overload
leading to CHF
Assessment
History: Allergies to penicillins,
cephalosporins, or other
allergens; renal disorders;
pregnancy; lactation 
Physical: Culture infection; skin
color, lesions; R, adventitious
sounds; bowel sounds: CBC,
liver and renal function tests,
serum electrolytes, Hct,
urinalysis 
Implementation
 Culture infection before
treatment; reculture if
response is not as
expected.
 Continue therapy for at
least 2 d after infection
has disappeared, usually
7---10 d.
 Reconstitute for IM use
to a dilution of 250
mg/1.5 mL using Sterile
Sodium Chloride
Injection. Discard after 3
d at room temperature or
after 7 d if refrigerated.
 Maintain epinephrine, IV
fluids, vasopressors,
bronchodilators, oxygen,
and emergency
equipment on standby in
case of serious
hypersensitivity reaction.
 DRUG INDICATION CONTRAINDICATON SIDE EFFECT
Paracetamol it is commonly used for  CNS: Lethargy,
Biogesic the relief of headaches, hallucinations, seizures
 GI: Glossitis, stomatitis,
and other minor aches
gastritis, sore mouth,
and pains, and is a
furry tongue, black
Drug classes major ingredient in
numerous cold and flu "hairy" tongue, nausea,
 Antipyretic vomiting, diarrhea,
 Analgesic remedies. In
abdominal pain, bloody
combination with opioid
diarrhea, enterocolitis,
analgesics, paracetamol
pseudomembranous
can also be used in the colitis, nonspecific
management of more hepatitis
severe pain such as post
 Hematologic: Anemia,
surgical pain and thrombocytopenia,
providing palliative care leukopenia,
in advanced cancer neutropenia, prolonged
patients.[2] The onset of bleeding time (more
common than with
analgesia is
other penicillinase-
approximately 11
minutes after oral resistant penicillins)
 GU: Nephritis--oliguria,
administration of
paracetamol,[3] and its proteinuria, hematuria,
casts, azotemia, pyuria
half life is 1–4 hours.
 Hypersensitivity: Rash,
fever,
wheezing, anaphylaxi
s Water for Injection or
 Local: Pain, phlebitis,
thrombosis at injection
site
 Other: Superinfections,
sodium overload
leading to CHF
NURSING CONSIDERATION
Assessment
History: Allergies to penicillins,
cephalosporins, or other
allergens; renal disorders;
pregnancy; lactation 
Physical: Culture infection; skin
color, lesions; R, adventitious
sounds; bowel sounds: CBC,
liver and renal function tests,
serum electrolytes, Hct,
urinalysis 
Implementation
 Culture infection before
treatment; reculture if
response is not as
expected.
 Continue therapy for at
least 2 d after infection
has disappeared, usually
7---10 d.
 Reconstitute for IM use
to a dilution of 250
mg/1.5 mL using Sterile
Sodium Chloride
Injection. Discard after 3
d at room temperature or
after 7 d if refrigerated.
 Maintain epinephrine, IV
fluids, vasopressors,
bronchodilators, oxygen,
and emergency
equipment on standby in
case of serious
hypersensitivity reaction.