DRUGS MECHANISM OF ACTION INDICATION CONTRAINDICATION ADVERSE EFFECTS

Commonly reported side

Lowering high cholesterol and
It is a member of the drug effects of atorvastatin
triglycerides in certain
class known as statins. It Active liver disease, include: nasopharyngitis,
patients. It also increases
is used for lowering which may include diarrhea, and arthralgia.
high-density lipoprotein
cholesterol. It is a unexplained persistent Other side effects
levels. It reduces the risk of
competitive inhibitor of elevations in hepatic include: urinary tract
heart attack, stroke, chest
hydroxymethylglutaryl- transaminase levels, infection, nausea, muscle
Atorvastatin pain caused by angina, or
coenzyme A (HMG-CoA) hypersensitivity to any spasm, limb pain,
blood vessel blockage. It is
reductase, the rate- component of this insomnia, myalgia, and
also used to reduce the risk of
determining enzyme in medication, pregnancy, musculoskeletal pain. See
congestive heart failure, or
cholesterol biosynthesis and nursing mothers below for a
the need for medical
via the mevalonate comprehensive list of
procedures to open blocked
pathway. adverse effects.
heart blood vessels.
Diazepam Diazepam acts at GABA A used in patients with muscle
synapses, and its action in spasm of almost any origin
reducing spasticity is at (including local muscle
least partly mediated in trauma), it also produces
the spinal cord because it sedation at the doses
is somewhat effective in required to reduce muscle
patients with cord tone
transection Chronic spasm due to
cerebral palsy, stroke, spinal
cord injury • acute spasm due
to muscle injury
It increases blood flow Parkinson’s disease Parasympathetic Abdominal pain,
and oxygen consumption Head injury hypertonia hypotension, tachycardia,
Citicholine in the brain. It also Cerebrovascular disorders bradycardia
involved in the
biosynthesis of lecithin.
Pantoprazole Substituted bezimidazole, Erosive esophagitis, peptic Concomitant use with Increased risk of
40 mg IV and also known as PPI ulcer, prophylaxis of NSAID- rilpivirine, atazanavir, Clostridium difficile-
due to its property to induced ulcers, zollinger- nelfinavir. Lactation associated diarhhea
block the final step of ellison syndrome
acid secretion by
inhibiting H+/K+ ATPase
enzyme system in gastric
parietal cell. Both basal
and stimulated acid are
inhibited

Dr.Chua Ho/Jumangit/Dela Cruz/Bandillo/Lopez/Caabay JIIC Rivera