Drug Analysis

Drug Mechanism of Indication Adverse reaction and Contraindication Nursing

action Side effects responsibilities
Generic: Losec, Suppresses gastric treatment of Respiratory: cough ,upper respiratory Hypersensitivity, Assess patient’s
Antra, Gastroloc, secretion by dyspepsia, peptic infection, asthemia, lactation and condition before
Mopral, Omepral, inhibiting ulcer disease CNS: headache, dizziness children starting therapy and
and Prilosec hydrogen/potassium (PUD), GI: abdominal pain, constipation, regularly thereafter
Brand: ATPase enzyme diarrhea ,flatulence, acid regurgitation to monitor drug’s
gastroesophageal
Omeprazole system in the nausea, vomiting effectiveness
reflux disease
Classification: gastric parietal cell, Musculoskeletal: back pain If adverse GI reaction
characterized as a (GERD) and Skin: Rash occurs monitor
Substituted Zollinger-Ellison
Benzimidazole gastric acid pump patients hydration
inhibitor syndrome, short Give capsules 30mins
Proton
term treatment of before meals, for oral
Pump inhibitor
Available form: active duodenal suspension 1 hr.
Capsules(10,20,40mg) ulcer, gastric before meals
Tablets 10mg ulcer ,pathologic Warn patient not to
Powder: 20mg hypersecretory crush or chew tablets
Route: conditions, or capsules
PO Lower doses aren’t
heartburn on 2 or
needed for patients
more days per with renal or hepatic
week impairments
Nursing Responsibilities:

1. Teel patient to swallow tablets or capsules whole and not to open, crush, or chew them.
2. Instruct patient to take drug 30 minutes before meals.

Drug Mechanism of Indication Adverse reaction and Contraindication Nursing

action Side effects responsibilities
Generic: Decadron, May stabilize Cerebral Edema, CNS: insomnia, psychotic behavior, Hypersensitivity, Monitor patient’s
Dexamethasone leukocyte inflammatory seizures, headache,vertigo use cautiously in weight, blood
Intensol, Dexasone, lysosomal conditions, CV: arrhythmias, edema, heart patients with pressure, glucose
Dexpak, membranes; allergic reactions, failure, hypertension, seizures, emotional level, and electrolyte
Mymethasone,Oradexo stimulate bone neoplasias, shock, thromboemolism. instability, levels, watch for
n marrow; and suppression test EENT: cataracts, glaucoma psychotic depression or
influence protein, for cushing GI: GI irritation, increased appetite, tendencies, recent psychotic episodes
Brand: Dexamethasone fat, and syndrome, pancreatitis, peptic ulcerartion MI, especially In
Classification: carbohydrate tuberculosis GU: menstrual irregularities thromboembolitic highdose therapy,
Glucocorticoids, anti- metabolism, meningitis, Metabolic: Carbohydrate disorders, heart For better results and
inflammatory, relieves cerebral bacterial intolerance, hyperglycemia, failure, less toxicity, give
immunosuppressant edema, reduces meningitis, to hypokalemia, negative nitrogen hypertension, GI once daily dose in the
Available form: inflammation and prevent balance caused by protein catabolism ulcer, diverticulitis, morning
Oral soln.- 0.5 mg/ 5ml, immune response, chemotherapy- Musculoskeletal: Growth nonspecific Give with food when
1mg/ml and reverses shock induced nausea suppression in children, muscle ulcerative colitis, possible, give IM
Tablet-0.25 mg, 0.5 mg, and vomiting weakness, osteoporosis. recent intestinal deep into gluteal
0.75 mg , 0.75 mg, 1 Skin: acne, allergic dermatitis, anastomosies, renal muscle. Rotae
mg, 1.5 mg, 2 mg, 4 delayed wound healing, hirsutism, disease, ocular injections sites to
mg, 6 mg skin eruptions, thin fragile skin, herpes simplex, prevent muscle
Route: urticaria cirrhosis, diabetes atrophy
Oral mellitus, If possible, avoid
hypothyroidism, giving drug
myasthenia gravis, subcutaneaously
osteoporosis, or because atrophy and
tuberculosis, use sterile abscesses may
cautiously in occur.
pregnant and Always adjust to
lactating women. lowest effective dose.
If patient’s stress
level(physical or
psychological)
increases, notify
prescriber and
increase dose
If patient has adverse
reaction, notify
prescriber, treat
symptoms and
provide supportive
therapy.
Tell patient not to
abruptly stop taking
the drug because this
may be fatal.
Teach patient the
early signs of adrenal
insufficiency(fatigue,
muscle weakness,
joint pain, fever,
anorexia, nauseam
dyspnea, dizziness
and fainting).
Warn patient about
easy bruising.