05/09/2018 Oral Desensitization to Penicillin for the Treatment of Pregnant Women with Syphilis: A Successful Program

Revista Brasileira de Ginecologia e Obstetrícia Services on Demand

Print version ISSN 0100-7203On-line version ISSN 1806-9339
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Abstract
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DALLE, Jéssica et al. Oral Desensitization to Penicillin for the Google Scholar H5M5 (2017)
Treatment of Pregnant Women with Syphilis: A Successful Program.
Rev. Bras. Ginecol. Obstet. [online]. 2018, vol.40, n.1, pp.43-46. ISSN Article
0100-7203. http://dx.doi.org/10.1055/s-0037-1606274.
English (pdf)
Gestational syphilis is a prevalent disease in Brazil and other low and
medium income countries. Desensitization to penicillin is recommended for English (epdf)
pregnant women with syphilis who are allergic to β-lactams. This is a Article in xml format
descriptive study utilizing outpatient medical records from 2011 to 2015
from a mother and child hospital that is part of the national healthcare Article references
system in the South of Brazil, which performs an average of 3,600 birth
How to cite this article
assistances per year. All cases of pregnant women with syphilis and
presumptive diagnosis of β-lactam allergy during the study period were SciELO Analytics
included. The patients referred for desensitization originated from the
hospital prenatal care service, as well as from municipal/state antenatal Automatic translation
care services. Oral desensitization was performed in the obstetric
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emergency room, and adult and pediatric intensive care units were available
at all times. Ten patients underwent desensitization during the period of Related links
study. Personal history of urticaria was the most common reaction that
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demanded desensitization. All patients tolerated the procedure well, and
showed no adverse reactions.We report a successful program of oral
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desensitization. None of the patients presented adverse reactions or
complications, a fact that corroborates the feasibility and safety of the More
desensitization protocol. Oral administration of penicillin comes at a low
cost, and optimizes the use of time and resources.
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Keywords : syphilis; pregnant women; penicillins; hypersensitivity.

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