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Centric relation: A historical and

contemporary orthodontic perspective


Donald J. Rinchuse and Sanjivan Kandasamy
J Am Dent Assoc 2006;137;494-501

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CLINICAL PRACTICE PRACTICAL SCIENCE

Centric relation
A historical and contemporary orthodontic perspective
Donald J. Rinchuse, DMD, MS, MDS, PhD;
Sanjivan Kandasamy, BDSc, BScDent, DocClinDen, MOrthRCS

he search for the optimal

T and preferred types of


static and functional ABSTRACT

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occlusions has occupied
the minds of dentists for Background. Centric relation (CR) has been a controversial subject in
more than a century. The possible dentistry for more than a century. For at least the past four decades,
role of occlusion in the etiology of issues involving CR have been of interest to orthodontists. The definition
temporomandibular disorders of CR has changed over the past half-century from a retruded, posterior
(TMD) also has been the subject of and, for the most part, superior condyle position to an anterior-superior
debate. Much of the occlusion/ TMD condyle position.
debate involves issues surrounding Type of Studies Reviewed. The authors addressed the historical
centric relation (CR), including defi- and contemporary orthodontic perspective of CR. The source material for
nition, recording and measurement, this review came mainly from literature and searches the lead author
use of articulators and deprogram- accumulated over the last 30 years. As there is no evidence-based (EB)
ming splints, and possible relation- model level 3 (systemic) review on the topic of CR, the best evidence on
ship to either stomatognathic health this subject was gleaned only from a thorough examination and evalu-
or disease. The purpose of this ation at EB model level 2 (experience plus best available sample studies).
article is to discuss some of the con- There was, however, enough high-quality EB model level 2 information
troversies concerning CR, particu- on the topic of CR for the authors to draw conclusions on the basis of a
larly as they relate to orthodontics. scientific appraisal of relevant research.
Because there is no evidence- Results. Although the reliability of CR records has been substantiated,
based (EB) model level 3 (systemic) the records’ validity has little to no evidentiary support. In addition,
review on the topic of CR, the best population-based sample studies and consensus statements from national
evidence on this subject can be conferences support the view that the positions of the temporomandibular
gleaned only from a thorough exami- joint (TMJ) condyles in relation to the glenoid fossa or CR position are not
nation and evaluation at EB model diagnostic of temporomandiblar disorders. There appears to be little to no
level 2 (experience plus best avail- benefit of using gnathologic records and articulator-mounted dental casts
able sample studies). However, to discern discrepancies in maximum intercuspation of the teeth coinci-
there is enough high-quality EB dent with TMJ condyles in an anterior-superior CR position in ortho-
model level 2 information on the dontic patients.
topic of CR to draw several note- Clinical Implications. The benefit of using gnathologic CR records
worthy conclusions. Therefore, we and articulators in orthodontics has not been substantiated by scientific
drew conclusions on the basis of a evidence.
scientific appraisal of relevant Key Words. Centric relation; condyle position; orthodontics.
research based on the EB model JADA 2006;137:494-501.
level 2 paradigm. One author
(D.J.R.) accumulated the majority of Dr. Rinchuse is a clinical professor, Orthodontics and Dentofacial Orthopedics, University of Pittsburgh,
the source material for this article School of Dental Medicine. Address reprint requests to Dr. Rinchuse at 510 Pellis Road, Greensburg,
Pa. 15601, e-mail “bracebrothers@aol.com”.
from literature and searches he con- Dr. Kandasamy is a research fellow in orthodontics, Oral Health Centre, University of Western Aus-
ducted over 30 years. tralia, Perth, and is in orthodontic practice, Perth, Australia.

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Copyright ©2005 American Dental Association. All rights reserved.
CLINICAL PRACTICE PRACTICAL SCIENCE

DEFINITIONS OF CENTRIC RELATION tions. A previously used term that all editions of
AND CENTRIC OCCLUSION the GPT considered obsolete and referenced along
with CO is “centric relation occlusion” (CRO).
Dentistry has not arrived at a consensus defini- Decades ago, CRO was used by gnathologists to
tion and concept of CR. In 2004, Christensen1 said describe the interocclusal position of the teeth
that he and most practitioners “accept the concept when the condyles were located in retruded CR.4,5
that CR is the most comfortable posterior location Past usage of the term “centric relation
of the mandible when it is bilaterally manipu- occlusion–centric occlusion” discrepancies, or
lated gently backward and upward into a retru- slides, was semantically appropriate. To avoid
sive position.” However, CR has not been recog- some of the confusion about the term “CR-CO,”
nized as a posterior, retruded condyle position for one publication appropriately used the term “CO
almost 20 years.2 In 2000, Jasinevicius and col- condyles” compared with CR.8 Recently, CO-CR
3
leagues found that faculty and students at seven (or CR-CO) and MI-CR (or CR-MI) in which MI is
dental schools could not agree on a unified defini- synonymous with CO, have been use interchange-
tion of CR. ably. Other “centric” terms found in the literature
The definition of CR has evolved over the past are intercuspal position (ICP), which is used syn-

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half-century from being a posterior and superior onymously with CO, and retruded cuspal position
position of the condyle in relation to (RCP), which is a modern reference
the glenoid fossa to an anterior- to the previously used term CRO.
superior position.2,4-7 Before 1987, Centric relation is a Hence, some publications have used
CR was considered a retruded the term “RCP-ICP” slides. In our
position of the
(posterior-superior) condylar posi- literature review, common and his-
tion. The latest edition of the Glos- condyles independent torical usage of terms will take
sary of Prosthodontic Terms (GPT)7 of tooth contact, precedent over any attempt for total
defines CR as “a maxillomandibular whereas centric accuracy.
relationship in which the condyles occlusion is an
articulate with the thinnest avas- CENTRIC RELATION AND
interocclusal dental ORTHODONTICS
cular portion of their respective
position of the
disks with the complex in the The call for orthodontists to con-
anterior-superior position against maxillary teeth sider the functional aspects of the
the slopes of the articular emi- relative to the dentition dates back to at least the
nences.” This edition of GPT also mandibular teeth. 1930s; several of the prominent pio-
includes six historical definitions neers were Brodie,9,10 Perry,11,12
7
of CR. Moyer,13 Thompson14-18 and
CR is a position of the condyles Ricketts.19,20 In the 1970s, Roth,21-25 a
independent of tooth contact, whereas centric gnathologic orthodontist, suggested that ortho-
occlusion (CO) is an interocclusal dental position dontists should embrace the principles of
of the maxillary teeth relative to the mandibular gnathology that had long been held by eminent
teeth.2 Maximum intercuspation (MI) has been prosthodontists and restorative dentists. He rea-
defined as “the complete intercuspation of soned that orthodontic treatment is analogous to
opposing teeth independent of condylar position.”6 doing full-mouth occlusal rehabilitation, with the
Although CO and MI have been used synony- difference being that orthodontics did not “cut” or
mously in the past, the most recent editions of modify the natural tooth structure. Purveyors of
GPT6,7 have made a distinction between the two this view were critical of nongnathologic ortho-
terms; this has not been well-received within the dontists for what they saw as their lack of con-
profession, most likely owing to resistance to cern about establishing an “optimal” functional
change. occlusion in addition to attaining the long-held
The common use of the terms “centric relation- traditional goals of static occlusion. A focus of this
centric occlusion” and “centric relation-maximum gnathologic orthodontic view was to establish a
intercuspation” discrepancies, or slides, in some retruded, posterior-superior “seated” CR position
publications is inaccurate, because CR is not com- when the interdigitating occlusion was in CO
parable with CO or MI. CR is a condyle position, (that is, CR-CO). The thinking then was that if a
while CO and MI are interocclusal dental posi- posterior-superior seated CR position was not an

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Copyright ©2005 American Dental Association. All rights reserved.
CLINICAL PRACTICE PRACTICAL SCIENCE

established goal of orthodontic treatment, CONDYLE POSITION AND CENTRIC SLIDES


patients would be prone to develop TMJ symp-
toms.21-25 Furthermore, the attainment of a The findings in the 1960s that centric slides
retruded, posterior-superior CR position would caused TMD were based on incorrect information
mitigate the development of TMD. from descriptive studies that lacked control/
Many aspects of this gnathologic orthodontic comparison groups. When control/comparison
view have been abandoned, particularly those groups that included subjects without TMD were
related to the attainment of a retruded, pos- added to the studies’ designs, the exact same cen-
terior-superior CR position. An impetus for this tric slides also were observed in these subjects
shift in thinking was the introduction of more (comparison group subjects who did not have
sophisticated TMJ imaging that demonstrates TMD). Hence, many of these studies had high
TMJ internal derangements and that has led to diagnostic sensitivity but poor diagnostic speci-
the change in the definition of CR from a pos- ficity, which led to false-positive TMD diag-
terior-superior to an anterior-superior position. noses.53,54 Furthermore, intraoral telemetry
The argument for anterior-superior positioned studies of the 1960s, in which miniature radio
condyles was the belief that distally displaced implants were placed in subjects’ fixed prostheses

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condyles can cause anterior and medial displace- and radio frequencies were monitored from out-
ment of the TMJ disks. With this thinking in side the mouth, found that even though entire
mind and relating it to orthodontics, Wyatt26 dentitions were reconstructed into retruded CR,
argued that Class II, division 2 malocclusions; subjects continued to use and function in CO.55-58
missing posterior teeth with bite collapse; any In a summary article, McNamara and colleagues59
occlusal contacts that may deflect the condyles found TMJ arthropathies associated with centric
posteriorly; and orthodontic procedures such as slides greater than 4 millimeters; however, they
the placement of Class II elastics, headgear, chin contended that the slides were the result of the
cups and certain retainers can cause TMD. How- TMD rather than the cause.
ever, this notion and others from this era were In summary, the preponderance of evidence
found to be untrue,27-47 particularly the idea that available suggests that there is no one ideal posi-
orthodontic treatment causes TMD.33,37,39,42-46 tion of the condyles in the glenoid fossa, but there
Changes in the definition and concept of CR is a range of “normal” positions.27,47,53,59 That is,
have been determined arbitrarily for the most the three-dimensional position and location of the
part and were not based on science and EB deci- condyles in the glenoid fossa are not predictive of
sion making. Concerning the ideas and notions TMD.60,61 Based primarily on dialectical consider-
of the early orthodontic gnathologists, John- ations rather than on evidence, anterior to
ston47 wrote, “It could be argued that the pro- mid-condyle positions appear to be favored over
gressive modifications in the definition of CR posterior, retruded positions.27-32,34-38
have done more to eliminate centric slides than
20 years of grudging acquiescence of the pre- RETRUDED CENTRIC RELATION:
THE PAST DATA
cepts of gnathology.”
Although contemporary orthodontic gnatholo- In the 1960s and 1970s, CRO was considered to
gists believe in attaining an anterior-superior be the interocclusal position of the teeth when the
condyle position at the same time the teeth are in mandibular condyles were in retruded CR.4 The
CR (CR-CO), there is little scientific evidence to location of retruded CR was calculated from an
support this view.27 In fact, the evidence supports interocclusal centric record (that is, CO and CRO)
a contrary notion. The location and position of the made from the teeth and not the condyles. Early
condyles in the glenoid fossa, irrespective of studies found that CO usually was 0.1 to 1.8 mm
where they may be, has not been demonstrated to anterior to CRO, depending on the population
be consequential to the presence or absence of studied and the age of the subjects.62-64 Chin-point
TMD symptoms.48-51 Keim52 said, “The neuromus- guided records found CO (or CRO) condyles to be
cular school tells us that there is a range of located on average 0.28 to 0.56 mm anterior and
acceptable positions (centric) … If we clinicians 0.26 to 0.85 mm inferior to retruded CR.65,66
continue to place emphasis on establishing ‘har- Although there was some variation in the find-
mony’ between CO and some mythical concept of ings from intraoral telemetric studies, the prepon-
CR, we are doing ourselves a disservice.” derance of evidence suggested that, though a few

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Copyright ©2005 American Dental Association. All rights reserved.
CLINICAL PRACTICE PRACTICAL SCIENCE

CRO contacts were found to occur during swal- degree, this has proven to be true. Orthodontic
lowing, most swallowing and all chewing contacts gnathologists recently have found only minor MI-
occurred in CO.55-58 Furthermore, lateral func- CR discrepancies for the vertical dimension, but
tional occlusal contacts originate from CO and not the horizontal and transverse dimensions.86
55-58
not from CRO. As we previously mentioned, The magnitude of the vertical MI-CR discrepancy
telemetry research has indicated that even when is approximately 1 mm. When the errors in
patients’ entire dentitions were reconstructed in method, recording and instrumentation are calcu-
retruded CR, they still persisted in using CO.58 In lated against this 1 mm figure, the importance of
addition, retruded CR was not believed to be a these findings can be insignificant.81 Nonetheless,
natural and physiological condyle position, but orthodontic gnathologists argue that considera-
rather an extreme border position.67-71 Interest- tion and measurements of MI-CR slides or dis-
ingly, Jankelson and colleagues72 supported the crepancies are still valid.21-25,86-92
view that neither CRO nor CO was physiological Using a Roth “power centric bite registration”
and, therefore, advocated what they and articulator-mounted models,
termed the “myocentric” position or Utt and colleagues90 found that CO
muscle (masticatory) -generated Many prosthodontists condyles were located on average

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centric position. They believed that use retruded centric 0.53 mm posterior and 0.72 mm
the myocentric position usually was relation only as a inferior to anterior-superior CR.
located between CRO and CO. On There was, however, a significant
guide so that dentures
the other hand, Schuyler 73 and amount of individual variation,
Mann and Pankey74 advocated a can be fabricated a with 39 percent of the CO condyles
“long centric” position, in which millimeter or so positioned anteroinferiorly from
occlusal prematurities, or interfer- anterior to this anterior-superior CR.90 Based on
ences, were eliminated to and from position. Utt and colleagues90 and Crawford,88
CRO and CO. orthodontic gnathologists claim that
anterior-superior CR slides average
CENTRIC RECORDS: RETRUDED 0.6 to 0.7 mm horizontally, 0.7 to 0.8 mm verti-
CENTRIC RELATION
cally and 0.27 to 0.3 mm transversely.89 Recent
The early literature on recording CR is related to investigations comparing gnathologic with non
retruded CR, not to anterior-superior CR. Fur- gnathologic finished orthodontic cases generally
thermore, most CR recordings are dentist- have found articulator-recorded MI-CR differences
manipulated, and there are differences in find- of 1 mm or greater in the vertical plane in non
ings from manipulated and unmanipulated CR gnathologically treated cases (1.41 mm for the
recordings.61 Dentist-manipulated CR records nongnathologically treated versus 0.41 mm for the
(also known as passive patient CR records) are gnathologically treated; difference of 1 mm).87
considered to be more reliable and less valid than
patient-manipulated records.75-84 One investiga- A CRITICAL APPRAISAL OF THE
CONTEMPORARY ORTHODONTIC
tion demonstrated the average range of centric GNATHOLOGIC APPROACH
slide for repeated recordings of retruded CR to be
0.30 mm mediolaterally and 0.27 mm anteropos- Today’s gnathologically oriented orthodontists
teriorly.85 It appears that recording of retruded advocate the use of articulators with dental casts
CR in contemporary dentistry makes sense only mounted in anterior-superior CR, with the major
in complete denture construction when no inte- goal of orthodontic treatment being to establish
rocclusal reference is possible. Even then, many coincidence of MI-CR.86,93 Accordingly, they
prosthodontists use retruded CR only as a guide believe that the tolerance for MI-CR discrepancies
so that dentures can be fabricated a millimeter or is 1.5 mm in the horizontal (H) and vertical (V)
so anterior to this position. planes and 0.5 mm in the transverse (T) plane
(average: Utt and colleagues,90 2.0 mm H and V,
ANTERIOR-SUPERIOR CENTRIC RELATION 0.5 mm T; Crawford,88 1.0 mm H and V, 0.5 mm
Logically, one would think that changing the defi- T).87-91 They further contend that articulator-
nition of CR from a posterior-superior to an mounted casts, instead of hand-held dental casts,
anterior-superior position would have eliminated are the only way to discern the MI-CR discrepan-
or reduced the magnitude of centric slides.47 To a cies. For instance, using articulator-mounted

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Copyright ©2005 American Dental Association. All rights reserved.
CLINICAL PRACTICE PRACTICAL SCIENCE

dental casts, Klar and colleagues89 found a statis- CR recordings do not place condyles in the posi-
tically, but perhaps not clinically, significant tions stated by their advocates. Alexander and
change in the pre– versus post–MI-CR recordings colleagues8 provided TMJ MRI documentation
(differences of no more than 0.39 mm in any of that condyles are not located in the assumed
the three spatial planes) among 200 consecutively positions as advocated and provided by several
gnathologically treated orthodontic patients. gnathologic centric bite registrations. Centric bite
Lastly, gnathologically oriented orthodontists registrations attempting to locate retruded
advocate the use of the terminal hinge axis posi- (posterior-superior) CR and contemporary ante-
tion, the need for pretreatment CR-MI–converted rior-superior CR do not correspond to the condyle
lateral cephalograms and the placement of positions of people with asymptomatic TMD.
gnathologic positioners immediately after ortho- CR gnathologic recording techniques such as
dontic appliances are removed.92 Roth power centric bite registration and articu-
On the other hand, nongnathologic orthodon- lator mounting instrumentation have been
tists tend to use hand-held models and demonstrated to be somewhat reliable (repeata-
noninstrument-oriented CR techniques. They bility and consistency of the records or tech-
favor more general treatment goals that include niques).91,92 We, however, question the validity of

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the attainment of the best occlusal relationship these recordings, as well as point out that there is
within the framework of optimal dentofacial error in them. For instance, one study found
esthetics, function and stability. Furthermore, standard deviations for gnathologic MI-CR
they believe that there is a tolerance for MI-CR records to be as high as 0.16 mm in the H and V
slides up to 2 to 4 mm in the horizontal plane planes and 0.13 mm in the T plane; the error was
with little or no attention given to the relevance calculated as 0.01 to 0.05 mm.92 Because there are
of the vertical and transverse dimensions.27,47,59 only small differences between gnathologic and
Orthodontic gnathologists argue that the nongnathologic MI-CR recorded discrepancies,
assessment of three-dimensional condylar posi- even a small amount of error calculated against
tion is not possible with two-dimensional TMJ any of the gnathologic study findings would fur-
radiography, but it is through the use of the Roth ther reduce the clinical significance of the find-
power centric bite registration with articulator- ings. Therefore, we ask if small centric MI-CR
mounted dental casts.21-25,65,86-93 This view may discrepancies found by gnathologists are clinically
ignore the possible benefit of TMJ magnetic reso- significant and whether they have any relation-
nance imaging (MRI) to assess condyle position.8 ship to patients’ stomatognathic health. Further-
Nevertheless, orthodontic gnathologists believe more, the gnathologic data may be based on ques-
that it is possible to locate a particular position of tionable research.27
the condyles precisely in the glenoid fossa via CR The validity of CR recordings and the use of
recordings. articulators in orthodontics is based on the con-
A two-piece bite registration technique by Roth cept of the terminal hinge axis. However, Pos-
called the “power centric bite registration” is selt’s94 1952 concept of a terminal hinge axis has
believed to seat the condyles in the optimal, been challenged by Lindauer and colleagues’95
anterior-superior CR position—or as Utt and col- theory of simultaneous and instantaneous rota-
leagues90 wrote, “condyles centered transversely tion and translation of the mandibular condyles.
and seated against the articular disk at the pos- According to this theory, the mandibular condyles
terior slope of the articular eminences without both initially rotate and translate around an axis,
dental interferences.” Roth,21-25 Kulbersh and col- which action continues as the jaw opens.
leagues,86,87 Crawford,88 Klar and colleagues,89 Utt In 1995, Lindauer and colleagues95 studied the
and colleagues,90 Schmitt and colleagues,91 Lavine condylar movements and centers of rotation
and colleagues92 and Cordray,93 however, failed to during jaw opening in eight subjects without
provide evidence (preferably MRI evidence) that TMD using a sonic digitizing system. They found
subjects’ condyles are positioned in a seated ante- that all of the subjects demonstrated both rota-
rior-superior CR. Hence, it can be argued that tion and translation during the initial phase of
there is no verification that the Roth power cen- jaw opening, and none had a center of rotation at
tric bite registration “captures” (positions and the condylar head. Their findings support the
records) condyles in anterior-superior CR.27 And theory of a constantly moving, instantaneous
contrary to Roth’s thinking, there is evidence that center of jaw rotation that is different for dif-

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Copyright ©2005 American Dental Association. All rights reserved.
CLINICAL PRACTICE PRACTICAL SCIENCE

ferent people. Because articulators do not incorpo- tric registration when a deprogrammer was used;
rate any initial translatory movement of the the difference may not be clinically significant.
condyles during jaw opening, Lindauer and col- Conversely, Kulbersh and colleagues87 did not
leagues95 concluded that the use of articulators to find a difference in MI-CR measurements
simulate “jaw movements to identify occlusal between orthodontic patients who wore full-
interferences cannot be expected to replicate the coverage deprogrammers for three weeks for 24
patient’s mandibular movement precisely.” They hours a day and those who did not.
further argue that “the uncertainty of predicting There are many unanswered questions con-
mandibular rotation for a given patient should be cerning deprogramming splints.
considered when planning surgical treatment and dIs there a difference in findings between ante-
fabrication of orthodontic appliances.”95 rior and full-coverage deprogrammers?
dWould a longer period of wearing a deprogram-
DEPROGRAMMING ming splint yield larger differences?
The need to “deprogram” patients from their pre- dAre the fractions-of-a-millimeter differences in
existing occlusions with occlusal centric registrations produced by
splints before taking CR recordings is deprogramming splints clinically

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controversial. Gnathologists in general The need to significant?
hypothesize that the mastication mus- ‘deprogram’ patients dHow much of the small centric
cles can affect adversely the from their differences between depro-
mandible’s position in the presence of pre-existing grammed CR records and tradi-
occlusal interferences owing to memo- tional records are due to
occlusions with
rized patterns and proprioceptive sen- recording and measurement
sory information.24 They also hypoth occlusal splints before errors?
esize that the condyles are prohibited taking centric relation dAre the deprogrammed
from being seated appropriately recordings is condyles being seated in the pre-
unless a deprogramming splint pre- controversial. dicted glenoid fossa position?
cedes CR bite registrations.93 Depro- dWhat is the reliability and
gramming splints are thought to pro- validity of deprogramming
vide a more physiological muscular splints for recording CR?
engram than what exists by allowing the mastica- dIs the deprogrammed centric registration a
tion muscles to mitigate temporarily the proprio- stable position?
ceptive errors caused by occlusal prematurities.21- dIs the deprogrammed position physiological?
25,89,93
Some orthodontic gnathologists21-25,93,96-98 dIs the deprogrammed position more physiologi
believe that patients, even patients without TMD, cal than the original centric position?
need to be deprogrammed before their CR records dDoes the deprogrammed centric position have
are obtained—sometimes for as long as three anything to do with stomatognathic health?
months. Some orthodontic gnathologists also
argue that orthodontic patient diagnosis is not CONCLUSIONS
complete unless deprogramming splints and artic- The definition of CR has changed over the past
ulator-mounted dental casts are used.21,98-100 half-century from a posterior and retruded
Nonetheless, use of deprogramming splints condylar position to an anterior-superior position.
lacks a true physiological basis and the evidence The evidence suggests that condyle position and
to support it is equivocal. While some investiga- CR position are not diagnostic of TMD. Although
tions have demonstrated a possible benefit of dentist-manipulated CR recordings are more reli-
deprogramming,101,102 others have not.87,103 In addi- able than unmanipulated CR recordings, they are
tion, articles have discussed the techniques, bene- less valid and physiological. Recent evidence sug-
fits or both of deprogramming.104-107 Both sample gests that the concept of a “terminal hinge axis”
studies used deprogrammers for relatively short may not be valid, as there is an “instantaneous
periods.102,103 Karl and Foley102 placed a “Lucia- center of rotation” in which the condyles actually
type anterior deprogramming jig” (that is, ante- rotate and translate simultaneously. There
rior tooth contact without posterior tooth contact) appears to be little benefit of using gnathologic
in 40 subjects with TMD for six hours and found records and articulator-mounted dental casts to
differences of only fractions of a millimeter in cen- discern MI-CR discrepancies in orthodontic

JADA, Vol. 137 http://jada.ada.org April 2006 499


Copyright ©2005 American Dental Association. All rights reserved.
CLINICAL PRACTICE PRACTICAL SCIENCE

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