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F U N D A M E N T A L S 37

Evaluation of Insomnia

Insomnia is defined as sleep difficulty (difficulty patient may be diagnosed with different subtypes
initiating or maintaining sleep, early morning by different experienced clinicians. This is not
awakening, or both) that is associated daytime con- surprising, as many patients manifest overlapping
sequences because of night time sleep difficulty, symptoms.
with the proviso that the nighttime or daytime Chronic insomnia disorder (CID) is defined
problems are not explained by an inadequate in the ICSD-3 and encompasses elements of
opportunity to sleep. The International Classifica- psychophysiologic insomnia, idiopathic insom-
tion of Sleep Disorders, Second Edition (ICSD-2) nia, paradoxical insomnia, insomnia associated
defined eight insomnia disorders (Tables F37-1 with mental disorder, inadequate sleep hygiene,
and F37-2).1 Other classifications such as that as well the behavioral insomnias of childhood
by Diagnostic and Statistical Manual of Mental Dis- (limit setting or sleep association disorders)
orders, Fourth Edition (DSM-IV) classified (Box F37-2 and see Table F37-2). The ICSD-
insomnia as primary insomnia and secondary 3 states that CID is characterized by “frequent
insomnia (insomnia associated with a mental dis- and persistent difficulty initiating or maintain-
order, medical disorder, or a drug or substance).2 ing sleep that results in general sleep dissatisfac-
The term comorbid insomnia has often been used tion.” CID may occur in isolation or be a
to refer to “secondary” insomnias, as it is often comorbid condition with a mental disorder,
difficult to define the relationship between medical condition, or substance use. Duration
insomnia and the associated disorder (which dis- of at least 3 months is required for the diagnosis
order is primary and which is secondary?). For of CID, and symptoms must occur on at least
example, insomnia may precede depression, 3 nights per week. Note that in ICSD-2, only
worsen during depression, and persist after a 1-month duration was required for many of
remission from depression. The ICSD-3 defines the insomnia disorders. More details on CID
only three insomnia disorders (see Table F37-1; are provided below. A number of other sleep
Box F37-1),3 and the ICSD-2 insomnia disorders disorders are associated with insomnia com-
have been consolidated into these three disorders. plaints (Table F3-3). These included sleep
The rationale is that previously used subtypes apnea syndromes, circadian rhythm sleep-wake
could not reliably be diagnosed.4 The same disorders, and the restless legs syndrome.

TABLE F37-1 Insomnia Disorders


International Classification of International Classification of
Sleep Disorders, 3rd Edition Sleep Disorders, 2nd Edition
Chronic insomnia disorder (CID) Psychophysiologic insomnia
- Frequency: on at least 3 nights per week Paradoxical insomnia
- Duration 3 months Idiopathic insomnia
Insomnia due to mental disorder
Inadequate sleep hygiene
Behavioral insomnia of childhood
Insomnia due to drug or substance
Insomnia due to medical condition
Short-term insomnia disorder (STID) Adjustment insomnia (acute
- Duration <3 months insomnia)
Other insomnia disorder
- Difficulty initiating or maintaining sleep but does not meet criteria for
CID or STID

584
FUNDAMENTALS 37 EVALUATION OF INSOMNIA 585

TABLE F37-2 Major Characteristics of Insomnia Types in International Classification of


Sleep Disorders, 2nd Edition
Insomnia Types Essential Features Clinical Clues
Psychophysiologic Duration at least 1 month Better sleep in novel environment (away
Anxiety about sleep from home)
Heightened arousal when in bed Can fall asleep outside bedroom or when
Conditioned sleep-preventing associations not trying to sleep
(bedroom as a stimulus for wake not
sleep)
Paradoxical Duration at least 1 month Objective sleep duration (PSG,
Extreme and physiologically improbable actigraphy) is much greater than
complaints: “I never sleep.” reported
Despite report of little sleep, relatively No or rare naps
minor daytime impairment
Idiopathic Onset in infancy or childhood Lifelong insomnia without remissions
No identifiable precipitant Insidious onset
No period of sustained remission
Associated with a Insomnia present for at least 1 month Insomnia waxes and wanes with mental
mental disorder Mental disorder has been diagnosed disorder
Temporally associated with mental
disorder (may precede by a few days or
weeks)
Inadequate sleep Improper sleep scheduling Variable bedtime and wake times
hygiene Use of products that disturb sleep near Napping
bedtime
Stimulating activities near bedtime
Use of the bed for nonsleep activities
Behavioral Falling asleep is an extended process Nighttime awakenings require caregiver
insomnia of Sleep-onset associations demanded intervention for return to sleep
childhood In absence of associated factors, sleep
sleep association onset delayed
type
Behavioral Difficulty initiating or maintaining sleep Caregiver demonstrates insufficient limit
insomnia of Refusal to go to bed or return to bed after setting to establish appropriate
childhood awakening behavior
limit-setting type
Adjustment Temporally associated with identifiable Recent psychological, psychosocial,
Insomnia stressor environmental, or physical stressor
Duration <3 months
Expected to resolve

Adapted from Schutte-Rodin S, Broch L, Buysee D, et al: Clinical guideline for the evaluation and management of chronic
insomnia in adults, J Clin Sleep Med 4:487-504, 2008.

SHORT-TERM INSOMNIA DISORDER


onset insomnia), difficulty maintaining sleep
This disorder encompasses what was previously (frequent awakenings, sleep maintenance
termed adjustment insomnia. The duration must insomnia), and early morning awakening.
be less that 3 months. In children, sleep difficulty is defined by
caregiver observation of resistance to going
to bed at an appropriate time and difficulty
OTHER INSOMNIA DISORDER maintaining sleep without parent or care-
giver intervention.
This diagnosis is reserved for individuals who 2. Daytime difficulty caused by sleep
complain of difficulty initiating and maintaining difficulty: Multiple complaints may be
sleep yet do not meet the full criteria for present, including fatigue, attention or con-
either CID or short-term insomnia disorder. centration difficulty, impaired social or aca-
demic performance, irritability, daytime
sleepiness, and reduced motivation. In chil-
MAJOR COMPONENTS OF CHRONIC dren, behavioral problems such and hyper-
INSOMNIA DISORDER activity, aggression, or impulsivity may be
prominent. Often, patients express dissatis-
1. Sleep difficulty: In adults, the major com- faction with sleep or concerns about the
plaints are difficulty initiating sleep (sleep effects of poor sleep on their health.
586 FUNDAMENTALS 37 EVALUATION OF INSOMNIA

BOX F37-1 Chronic Insomnia Disorder—Diagnostic Criteria ICSD-3


Criteria A-F must be met 5. Daytime sleepiness
A. The patient reports or the patient’s parent or 6. Behavioral problems (e.g., hyperactivity,
caregiver observes one or more of the following: impulsivity, aggression)
1. Difficulty initiating sleep 7. Reduced motivation/energy/initiative
2. Difficulty maintaining sleep 8. Proneness for errors/accidents
3. Waking up earlier than desired 9. Concerns about or dissatisfaction with sleep
4. Resistance to going to bed on appropriate C. The reported sleep/wake complaints cannot be
schedule explained purely by inadequate opportunity (i.e.,
5. Difficulty sleeping without parent or care- enough time is allotted for sleep) or inadequate
giver intervention circumstances (i.e., the environment is safe, dark,
B. The patient reports or the patient’s parent or quiet, and comfortable) for sleep.
caregiver observes one or more of the following D. The sleep disturbance and associated daytime
related to the nighttime sleep difficulty: symptoms occur at least three times per
1. Fatigue/malaise week.
2. Attention, concentration, or memory E. The sleep disturbance and associated daytime
impairment symptoms have been present for at least
3. Impaired social, family, occupational or aca- 3 months.
demic performance F. The sleep/wake difficulty is not better explained
4. Mood disturbance/irritability by another primary sleep disorder.

Adapted from American Academy of Sleep Medicine: International classification of sleep disorders, ed 3, Darien, IL, 2014, American
Academy of Sleep Medicine.

BOX F37-2 Short-Term Insomnia defined and the duration of the complaint deter-
Disorder mined. The history of the origin of the complaint,
including age of onset should be explored, and
ICSD-3 DIAGNOSTIC CRITERIA particular life events or stressors at the start of
(Criteria A to E must be met) the problem should be identified. For example,
A, B, C. As in Chronic Insomnia Disorder patients with the subtype idiopathic insomnia
D. The sleep disturbance and associated daytime report problems since childhood or adolescence
symptoms have been present for less than with an insidious onset. Patients with psycho-
3 months. physiologic subtype of insomnia may report that
E. The sleep/wake difficulty is not better explained chronic insomnia began after a severe illness.
by another primary sleep disorder. Presleep conditions or activities that could affect
sleep, including the bedroom environment,
activities near bedtime, or mental state near bed-
time should be explored. The bedroom environ-
3. Frequency, duration, adequate sleep ment should be characterized for factors that
opportunity or environment: A frequency might disturb sleep (noise, clock easily seen from
of at least 3 nights per week, a duration of the bed, extreme hot or cold temperature). Activ-
3 months, and the requirement of an ade- ities near bedtime, including working late on the
quate opportunity and environment for sleep computer, drinking caffeinated beverages or
are requirements for the diagnosis of CID. alcohol in the evening, or exercise near bedtime,
The ICSD-3 states that patients with chronic may impair the ability to sleep. The mental status
insomnia characterized by recurrent epi- at bedtime should be explored. Often, patients
sodes of sleep/wake difficulties lasting several began worrying about their stresses and prob-
weeks at a time (<3 months) over several lems when retiring for the night. The presence
years may also qualify for the CID diagnosis. or absence of nocturnal symptoms, including snor-
ing, gasping during sleep, symptoms of restless
legs syndrome (RLS), and body movements
INSOMNIA EVALUATION should be evaluated.
The sleep-wake schedule should be determined
A detailed sleep history is the cornerstone of by report including variability of bedtime and
evaluation of insomnia.5–9 First, the nature of rise time as well as the frequency and duration
the primary sleep complaint (problems with sleep of naps. Factors that worsen or improve sleep
onset, sleep maintenance, or quality) should be should be detailed. For example, some patients
FUNDAMENTALS 37 EVALUATION OF INSOMNIA 587

with insomnia report sleeping better in a novel sleep apnea, insomnia symptoms are more likely
environment (reverse first-night effect).10 to be present in women than in men.1 The circa-
Patient recall may be supplemented by sleep dian sleep-wake rhythm disorders (CSWRDs)
logs, actigraphy, or both, as discussed in a fol- may also be associated with insomnia com-
lowing section. Daytime function should be dis- plaints, including delayed sleep phase syndrome
cussed with emphasis on possible consequences (sleep-onset insomnia) and advanced sleep phase
of insomnia. Reports of daytime fatigue or syndrome (early morning awakening). In delayed
impaired cognition and mood are more sleep phase syndrome, once the affected indi-
common than true daytime sleepiness. True day- viduals are able to fall asleep, they have fairly
time sleepiness should trigger suspicion for additional normal sleep. In advanced sleep phase syndrome,
sleep problems such as sleep apnea, narcolepsy, or individuals fall asleep early but then awaken in the
depression. Daytime activities that may affect sleep early morning hours. In non–24-hour CSWRD,
such as the amount of caffeine, alcohol, exercise, patients may report periods of insomnia alternating
sunlight exposure, and napping should be with hypersomnia.1,3 RLS or periodic limb move-
detailed. A general medical and psychiatric history ment disorder (PLMD) may be associated with
is important to identify mental or medical condi- symptoms of insomnia or nonrestorative sleep.
tions that may affect sleep. A detailed medication A number of medications may also disturb sleep
history including over-the-counter medications quality (e.g., caffeine).
and substances of abuse is extremely important.
A physical examination and appropriate labo-
ratory testing if not recently performed should
rule out obvious medical causes of insomnia. QUESTIONNAIRES, SLEEP LOGS,
Examination of the upper airway showing a high AND ACTIGRAPHY
Mallampati score (upper airway narrowing)11
might trigger suspicions of obstructive sleep Supporting information from questionnaires
apnea (OSA). (mood, cognition about insomnia), sleep logs,
and actigraphy may be helpful in evaluating
patients with insomnia (Box F37-4 and Box
DIFFERENTIAL DIAGNOSIS F37-5). These may supplement other information
obtained from the sleep history. Assessing the
Major characteristics of the insomnia types listed patient’s attitudes about sleep and the sleep prob-
in the ICSD-2 are listed in Table F37-2. Patients lem is as important as documenting the degree of
with CID often have characteristics of more sleep disturbance. In addition, some patients are
than one type. A number of non CID sleep dis- hesitant to admit to feelings of depression. Sleep
orders may be associated with insomnia com- logs and actigraphy provide a more accurate esti-
plaints (Box F37-3). Sleep apnea syndromes mate of the patient’s sleep quantity than is possi-
may be associated with repetitive arousal and ble from patient recall.
sleep-maintenance problems. In patients with The Epworth Sleepiness Scale (ESS; see
Fundamentals 17) is used to assess subjective
estimates of the propensity to fall asleep in
BOX F37-3 Other Sleep Disorders common situations.12 The Pittsburgh Sleep
Associated with Insomnia Quality Index (PSQI) is a 24-item self-report
Complaints measure of general sleep quality that specifically
addresses the preceding 1-month period. The
1. Sleep apnea syndromes PSQI evaluates seven domains, including the
2. Circadian rhythm sleep/wake disorders
duration of sleep, sleep disturbance, sleep-onset
a. Delayed sleep/wake disorder type—sleep-
onset insomnia latency, daytime dysfunction because of sleepi-
b. Advanced sleep/wake disorder—early AM ness, sleep efficiency, need for medications to
awakening sleep, and overall sleep quality. The PSQI
c. Irregular sleep phase type—at least three yields a global score and seven component
sleep episodes per 24 hours scores (poor sleep: global score > 5).13,14 The
d. Non-24 hour sleep phase type—alternating questionnaire has been shown to distinguish
periods of insomnia and hypersomnia among healthy patients, patients with depres-
3. Restless legs syndrome/periodic limb move- sion, and patients with sleep disorders. It was
ment disorders not designed specifically for insomnia but
From American Academy of Sleep Medicine: International
has been used in insomnia assessment and treat-
classification of sleep disorders: diagnostic and coding manual, ed ment studies. Detailed instructions for use and
3, Darien, IL, 2013, American Academy of Sleep Medicine. scoring of the PSQI are available at the
588 FUNDAMENTALS 37 EVALUATION OF INSOMNIA

BOX F37-4 Evaluation of Insomnia


1 SLEEP HISTORY • Work schedule and disturbance
A. Define primary complaint: • Caffeine and alcohol intake
• Delayed sleep onset H. Medical and psychiatric conditions (e.g., chronic
• Sleep maintenance problems pain, depression) or medications that may affect
• Frequent awakenings/early morning awakening sleep
• Nonrestorative sleep
2 PHYSICAL AND MENTAL STATUS
B. Define time course of complaint:
EXAMINATION
• Age of onset
• Precipitating event or stressor A. Narrow upper airway (high Mallampati score),
C. Evaluate presleep conditions: retrognathia
• Pre-bedtime activities
3 SUPPORTING INFORMATION
• Bedroom environment
• Physical and mental status before sleep A. Sleep/mood questionnaires:
D. Nocturnal symptoms (awakenings, physical or mental • Epworth Sleepiness Scale
symptoms, including snoring or body movements) • Dysfunctional Beliefs and Attitudes about
E. Sleep-wake schedule—by patient report includ- Sleep
ing variability, naps • Pittsburgh Sleep Quality Index
F. Daytime function—consequences of insomnia: B. Sleep log for 2 weeks—attention to sleep and
• Sleepiness versus fatigue wake time variability, general patterns
• Impairment of mood, cognitive dysfunction, C. Actigraphy
quality of life
4 SLEEP STUDY—NOT ROUTINELY INDICATED
G. Daytime activities relevant for sleep:
• Sunlight exposure, exercise A. Indicated when another sleep disorder such as
• Napping sleep apnea is suspected.

University of Pittsburgh Sleep Medicine Institute


BOX F37-5 Questionnaires to Evaluate web site http://www.sleep.pitt.edu/content.asp?
Patients with Insomnia id¼1484&subid¼2316.
The Beck Depression Inventory (BDI-I
Epworth Sleepiness Propensity to fall asleep in
or BDI-II) is a 21-item self-report inventory
Scale eight situations (0 never, 1
slight, 2 moderate, 3 high
(Box F37-5) used to measure manifestations of
chance) with a total score depression, each item being scored from 0 to
0 to 24. Normal  10 3.15,16 Higher total scores indicate more severe
Beck Depression BDI or BDI-II is a 21-item depressive symptoms. The BDI-II is a revision of
Inventory self-report inventory used the original BDI-I. Because primary insomnia
to measure depression. and major depression share some daytime symp-
BDI-1 scores: Minimal or toms, the usual cutoff scores for the BDI might
no depression BDI < 10, be less specific for depression in insomnia
moderate to severe patients.17 The Dysfunctional Beliefs and Atti-
depression BDI  19
tudes about Sleep (DBAS) Questionnaire is a
BDI-II scores: Minimal or
no depression BDI < 14, self-rating survey to assess negative cognitions
moderate to severe about sleep.18,19 Reversal of these cognitions is a
depression BDI  20 goal of the cognitive component of cognitive
Pittsburgh Sleep A 24-item self-report behavioral therapy (CBT). The original DBAS
Quality Index measure of sleep qualities was a 30-item questionnaire, in which patients
(poor sleep: global score responded using an analog scale (0, strongly dis-
>5) agree; 1, 2, 3. . . , to 10, strongly agree). A shorter
Dysfunctional Beliefs DBAS is a self-rating of 30 version (DBAS-16)19 has recently been validated
and Attitudes About statements that is used to and is less time-consuming for patients to complete
Sleep Questionnaire assess negative cognitions
(Figure F37-1).
about sleep. Shorter
version the DBAS-16 also
exists (see Appendix 1).
SLEEP LOGS
BDI, Beck Depression Inventory; DBAS, Dysfunctional
Beliefs and Attitudes about Sleep; PSQI, Pittsburgh Sleep A sleep log (sleep diary) for at least 2 weeks is
Quality Index. recommended when evaluating patients with
FUNDAMENTALS 37 EVALUATION OF INSOMNIA 589

Strongly Strongly
Disagree Agree
Name 1 2 3 4 5 6 7 8 9 10
1. I need 8 hours of sleep to feel refreshed and function well during the day.

2. When I don’t get a proper amount of sleep on a given night, I need to catch up on the
next day by napping or on the next night by sleeping longer.

3. I am concerned that chronic insomnia may have serious consequences


on my physical health.

4. I am worried that I may lose control over my abilities to sleep.

5. After a poor nights sleep I know that it will interfere with my


daily activities on the next day.

6. In order to be alert and function well during the day, I believe would be
better off taking a sleeping pill rather than having a poor nights sleep.

7. When I feel irritable, depressed, or anxoius during the day


it is mostly because I did not sleep well the night before.

8. When I sleep poorly on one night, I know it will distrub my sleep schedule
for the whole week.

9. Without an adequate night’s sleep I can hardly function the next day.
10. I can’t ever predict whether I’ll have a good or poor night’s sleep.

11. I have little ability to manage the negative consequences of distrubed sleep.

12. When I feel tired, have no energy, or just seem not to function well
during the day, its generally because I did not sleep well the night before.

13. I believe insomnia is essentially the result of a chemical imbalance.


14. I feel insomnia is ruining my ability to enjoy life and prevents me from doing what I want

15. Medication is probably the only solution to sleeplessness.

16. I avoid or cancel obligations (social, family) after a poor night’s sleep.

FIGURE F37-1 n Dysfunctional Beliefs and Attitudes About Sleep (DBAS)-16. (From Morin CM, Vallières A, Ivers H:
Dysfunctional beliefs and attitudes about sleep (DBAS): validation of a brief version (DBAS-16), Sleep 30:1547-1554, 2007.)

insomnia. Sleep logs are often more accurate and also typically provide space to record caffeine
more reliable than patient recall of their chronic consumption, bedtime activities, or medications
sleep patterns. Sleep logs usually follow a ques- taken for sleep as well as estimates of sleep qual-
tion format or time plot graphic format.20 An ity. Sleep logs are very helpful in revealing general
adaptation of a basic consensus sleep log20 is patterns of the sleep-wake cycle such as irregular bed-
shown in Figure F37-2. The reader should look times and wake times and the amount and frequency
at Patient 111 for other examples. The essential of napping. A few characteristic patterns noted in
elements of a sleep log include the ability to sleep logs are listed in Box F37-6.
assess time in bed (TIB), sleep-onset latency
(SOL), total sleep time (TST), and the amount
of wakefulness after sleep onset (WASO). The ACTIGRAPHY
TIB is the period from when the patient gets
in bed until the final time the patient leaves the Actigraphy involves use of a portable device
bed in the morning. WASO includes all wake (often resembling a watch and typically worn
from sleep onset until the patient leaves the on the wrist) that collects movement information
bed in the morning. The patient need report only (activity) over an extended period (Figure F37-3).
three of these four parameters because they are The absence of movement is assumed to be a sur-
related (TIB ¼ SOL + TST + WASO). Sleep effi- rogate of sleep.21 The use of actigraphy is included
ciency can be computed (¼ TST  100/TIB), in the ICSD-3 diagnostic criteria for several circa-
with normal values exceeding 85%. Sleep logs dian sleep wake rhythm disorders.3 Practice
590 FUNDAMENTALS 37 EVALUATION OF INSOMNIA

FIGURE F37-2 n Sleep log. (Adapted from Carney CE, Buysse DJ, Ancoli-Israel S, et al: The consensus sleep diary: standard-
izing prospective sleep self-monitoring, Sleep 35[2]:287-302, 2012.)

insomnia, the AASM practice parameters did not


BOX F37-6 Some Typical Sleep Log state that actigraphy was indicated as a routine eval-
Patterns uation of patients with insomnia.
Actigraphy does not measure sleep as defined
Delayed sleep Late bedtime or long sleep
by electroencephalography (EEG), electroocu-
phase latency, few awakenings,
normal sleep duration on lographic (EOG), or chin electromyographic
weekends or non-work/ (EMG) criteria or the subjective experience of
non-school days sleep (as measured by sleep logs and question-
Inadequate sleep Irregular wake and rise naires). Therefore, it is not surprising that esti-
hygiene times, naps mates of TST, wake time, and sleep latency
Psychophysiologic Long sleep latency, from sleep logs and actigraphy may differ from
insomnia decreased total sleep time, PSG findings.24,25 Algorithms have been devel-
frequent awakenings oped to estimate TST and WASO from the
Variability in sleep quality activity data. Actigraphy estimates of sleep dura-
Paradoxical Nights of minimal or no
tion, WASO, and sleep latency are more accurate
insomnia sleep are reported followed
by no or few naps the in normal individuals than in patients with
next day insomnia. Periods of low activity in which
patients lie quietly in bed but are awake may
be scored as sleep by actigraphy software. When
parameters for use of actigraphy have been pub- performing actigraphy, it is essential to require
lished by the American Academy of Sleep Medicine patients to complete a sleep log (e.g., lights off,
(AASM.22,23 Although actigraphy is indicated for lights on, out of bed, actigraph off for shower;
determining the circadian patterns of patients with TST; sleep latency). This information enables
FUNDAMENTALS 37 EVALUATION OF INSOMNIA 591

FIGURE F37-3 n Actigraphy from a good sleeper and a patient with insomnia. B, Bedtime ready to sleep. The patient
with insomnia had long sleep latency and two prolonged awakenings as well as a nap.

a correct interpretation of actigraphy tracings. If BOX F37-7 Typical Polysomnography


the actigraphy estimate of TST far exceeds patient Findings in Patients with
estimates, this would suggest paradoxical insomnia. Insomnia
Sleep logs and actigraphy provide comple-
mentary information. Actigraphy is most valu- • Increased sleep latency (>30 minutes)
able in determining the pattern of wake and • Decreased TST
sleep. It can detect irregular bedtimes and wake • Decreased sleep efficiency
times and naps. Sleep logs are always filled out by • Increased stage N1 (%TST)
patients wearing an actigraph. They provide • Decreased stage N3 (%TST)
complimentary information. Sleep logs may • Increased REM latency
• Decreased REM latency (depression)
overestimate sleep latency while actigraphy
underestimates sleep latency (lying still but REM, Rapid eye movement; TST, total sleep time.
awake). Sleep logs may underestimate total sleep
time, and actigraphy overestimate total sleep.
The relationship among PSG, actigraphy, and
sleep log findings also may differ depending on psychophysiologic insomnia, the “reverse first-
the groups studied. night effect”10 may be noted. In these patients,
the sleep quality in the sleep center is better than
that reported at home. It is essential to have all
patients complete questionnaires assessing sub-
POLYSOMNOGRAPHY jective sleep (estimate TST, sleep latency, sleep
quality) after PSG.
PSG is not indicated for the routine assessment
of insomnia. The 2003 AASM practice parame-
ters for the role of PSG in insomnia state: CO-MORBID INSOMNIA
“PSG is indicated when the initial diagnosis (insom-
nia) is uncertain, treatment fails (either behavioral or Many comorbid conditions such as chronic pain
pharmacologic), or precipitous arousals occur with vio- disorders may cause the sleep/wake complaints.
lent of injurious behavior (Guideline).9 When PSG If such conditions are the sole cause of the sleep
is performed, typical findings (Box F37-7) in difficulty, a separate insomnia diagnosis may not
patients with insomnia include long sleep latency apply. The ICSD-3 states one should ask “How
(>30 minutes), reduced TST, increased WASO, much of the time does the sleep difficulty arise as
and reduced sleep efficiency. Long rapid eye a result of factors directly attributable to the
movement (REM) latency, a high arousal index, comorbid condition (e.g., pain ?)” or “Are there
increased stage N1, and decreased stage N3 sleep times that the sleep/wake complaints occur in the
may also be noted. In patients with paradoxical absence of these factors?” If there is evidence that
insomnia, objective sleep abnormality is much the patient’s sleep/wake complaints are not
less severe than reported. It is not unusual for solely caused by the medical condition, and those
such patients to report little or no sleep following sleep/wake complaints seem to merit separate
a PSG documenting only mild to moderate dec- treatment attention, then a diagnosis of chronic
rements in the TST. In some patients with insomnia disorder should be made.
592 FUNDAMENTALS 37 EVALUATION OF INSOMNIA

CLINICAL PEARLS
1. The diagnosis of CID requires the presence of (a) sleep difficulty, (b) daytime consequences, (c) difficulty for
at least 3 nights per week for at least 3 months, and (d) adequate opportunity and environment for sleep.
2. Sleep difficulty may include problems initiating or maintaining sleep, and early morning awakening. In chil-
dren, sleep difficulty includes resistance to going to bed and difficulty sleeping without caregiver
intervention.
3. A good sleep history is the essential tool for evaluating insomnia. PSG has only a limited role in this
evaluation.
4. Sleep logs and actigraphy provide complementary information, so the use of both can be valuable.
5. A number of insomnia disorders in ICSD-2 are now included in the ICSD-3 diagnosis of chronic insomnia
disorder.

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