DRUG STUDY

No Generic Brand Name Dosage Frequency Indication Contraindication Nursing consideration

Name

1. Atorvastatin Lipitor 40mg 1 tab OD To reduce the risk Contraindicated in Monitor patient’s lipid and
of MI, stroke, patients liver function levels at
angina and hypersensitive to baseline and periodically
revascularization the drug and in thereafter
procedures in those with active
patient with no liver disease or Monitor patient for sign of
evidence of CAD condition linked rhabdomyolysis, especially
with multiple factor with unexplained if taking more than one
heteroxygous persistent class of lipid
familial increases in Lowering drugs
hypercholesterolemi transaminase
a adjunct to diet to levels Adolescent Asses patien’s and family’s
reduce elevated girl must be at knowledge of drug
LDL total least 1 year post therapy.
cholesterol, Apo B menarche.
and tryglyceride
level to increase
HDL level in
patients with
primary

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 hypercholesterolemi
a and mixed
dylipidemia

2. Spironolacton Aldactone 25 mg 1 tab OD  Diagnosis and Anuria,  Mark calendars of

e hyperkalemia,
maintenance of edema outpatients as
acute or
primary reminders of alternate
progressive renal
hyperaldostero insufficiency. day or 3- to 5-day/wk
nism Addison’s disease therapy.
 Adjunctive  Give daily doses early
therapy in so that increased
edema urination does not
associated with interfere with sleep.
CHF, nephrotic  Make suspension as
syndrome, follows: Tablets may be
hepatic pulverized and given in
cirrhosis when cherry syrup for young
other therapies children. This
are inadequate suspension is stable for
or inappropriate 1 mo if refrigerated.
 Treatment of  Measure and record
hypokalemia or regular weight to
prevention of monitor mobilization of
hypokalemia in edema fluid.

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 patients who  Avoid giving food rich
would be at in potassium.
high risk if Arrange for regular
evaluation of serum
hypokalemia
electrolytes and BUN
occurred:
Digitalized
patients,
patients with
cardiac
arrhythmias
 Essential hypert
ension, usually
in combination
with other
drugs.
3. Carvedilol Coreg 25 mg 1 tab 6AM-  Hypertension,  Contraindicated  Consult with physician
6PM
alone or with with decompens about withdrawing drug
other oral drugs, ated CHF, if patient is to
especially diuret bronchial undergo surgery (withdr
ics asthma, heart awal is controversial).
 Treatment of block, cardiogen  Give with food to
mild to severe ic shock, decrease orthostatic
CHF of ischemic hypersensitivity hypotension and

59
 or cardiomyopat to carvedilol, adverse effects.
hic origin pregnancy, lacta  Monitor for orthostatic
with digitalis, di tion. hypotension and provide
uretics,ACE  Use cautiously safety precautions.
inhibitors with hepatic  Monitor patients
 Left ventricular impairment, with diabetes closely;
dysfunction peripheral drug may mask
(LVD) after MI vascular hypoglycemia or worsen
disease, thyroto hyperglycemia
xicosis, diabetes
,anesthesia,
major surgery
4. Clopidogrel Plavix 75 mg 1 tab OD  Treatment of  Contraindicat  Provide small, frequent
patients at risk ed with allergy meals if GI upset occurs
for ischemic to clopidogrel, (not as common as with
events—history active aspirin).
of MI, pathological  Provide comfort
ischemic stroke, bleeding such measures and arrange
peripheral artery as peptic ulcer for analgesics if
disease or intracranial headache occurs.
 Treatment of hemorrhage,
patients with lactation.
acute coronary  Use

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 syndrome cautiously with
bleeding
disorders,
recent surgery,
hepatic
impairment,
pregnancy.

5. Micardis Telmisartan 40 mg 1 tab OD  Coronary  Hypersensitivi  Monitor BP carefully

Artery Disease ty to after initial dose and
telmisartan or periodically
 Hyperthropic other thereafter.monitor
cardiomyophat angiotensin more frequently with
y receptor perxisting biliary
 CHF antagonist obstructive disorder or
hepatic insufficiency.
 Hypotension,  Pregnancy
renal artery first semester  Monitor dyalisis
stenosis patients closely for
 lactation orthostatic or hepatic
hypotension

 Lab test : periodic

Hemoglobin,
creatinine clearance,

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 liver enzyme

 Monitor concomitant
dogoxin levels
throughout therapy.

6. Diltiazem Cardizem 120 mg 1 tab OD  CHF (especiallyKnown  Check BP and ECG

if patient is also
hypersensitivity to before initiation of
receiving beta
drug; sick sinus therapy and monitor
blocker) syndrome (unless particularly during
pacemakaer is in dosage adjusment
 Conduction place and period
abnormalities, functioning),
renal or hepar second or third  Lab test : do baseline
impairment, degree AV Block; and periodic liver and
older adults severe hypotension renal function test.
(systolic <90 mm  Monitor for and report
Hg or diastolic S&S of CHF
<60 mmHg);
patients  Monitor for headache.
undergoing An Analgesic may be
intracranial required.
surgery; bleeding
 Supervise ambulation
aneurysm.
as indicated

7. Salmeterol Salmeterol 250 mcg 1 pups OD  Cardiovascular  Hypersensitivity  Withhold drug and
notify physician

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 Xinafoate disorder to salmeterol immediately if
bronchospasm occur
 Cardiac  Primary following its use
arrhytmias treatment of
status asmaticus  Monitor
 Hypertension cardiovascular status,
 Pregnancy report tachycardia
 History of (category C)
seizures or  Monitor liver enzymes
thyrotoxicosi  Lactation periodically with long-
 liver and renal term therapy.
impairment

 older adults

 Diabetes
mellitus

 Sensistivity to
other beta
adrenergic
agonists

8. Ascorbic Acid Vita-C 500 mg 2 tab on 6  Excessive  Use of sodium  Lab test : periodic
AM doses in ascorbate in HCT&Hgb, serum
patients with patients on electrolytes
2 tab on 6 G6PD sodium
PM deficiency restriction  Monitor for S&S of
acute hemolytic anemia,

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  Hemochromat  Use of calcium sickle cell crisis
osis ascorbate in
patients
 Thalasemia receiving
 Sideroblastic digitalis
anemia

 Sickle cell
anemia

 Patients prone
to gout or
renal calculi

9. Multivitamin Multivit 1 tab OD  Treating or  Allergic to  Monitor dosage and

and Minerals Centrum preventing low any ingredient side effect of centrum
Silver level of in centrum such as : allergic
vitamins and reaction, swelling of
minerals in the the mouth, face, lips or
body tongue, burning,
numbness or tingling

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