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ORTHOPAEDIC COATINGS
LEIF SHARKEY
43171091
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TABLE OF CONTENTS
1.1. EXPLORING OF HA COATINGS & DERIVATIVES OF, IN THE FIELD OF ORTHOPAEDICS ................... 1
1.2. AVAILABLE INNOVATION SPACE ........................................................................................................... 1
1.3. CURRENT STATE OF IP DEVELOPMENT................................................................................................. 1
4.1. WORK FLOW, MEASURABLE PERFORMANCE INDICATORS & RESOURCE STRATEGIES (MICHIGAN
TECH) ................................................................................................................................................................. 5
4.2. CONCLUSION ........................................................................................................................................... 5
5. REFERENCES .......................................................................................................................................... 6
APPENDIX A ................................................................................................................................................... 7
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APPENDIX B.................................................................................................................................................... 8
APPENDIX C ................................................................................................................................................... 9
APPENDIX D ................................................................................................................................................. 10
LIST OF TABLES
Table 1: Itemised checklist for sustaining a commercial presence ......................................................................................3
LIST OF FIGURES
Figure 1: Summarises medium-long term goals ..................................................................................................................2
Figure 2: Typical timeline for dental implant (Dental Implants Dublin, 2018) .................................................................10
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1. FREEDOM TO OPERATE
1.1. Exploring of HA Coatings & Derivatives of, in the Field of Orthopaedics
Patents under review of their respective claims, validity and evidenced with supporting data are
similar work developed through advancing applications by the inventors. Followed by Malshe et al.
(2008) publishing an electrostatic spray to deposit nanostructured hydroxyapatite (HA) coating for
biomedical applications. Malshe et al. verifies early works by Gitzhofer et al. (1994) which patented
plasma spraying technologies, but was further developed through published work in 2018. Main
disparity between Patent #1 and #2 is a “registered” viable method of creating a porous HA surface
using a premixed suspension of a HA composition and Malshe et al. (2012) using the electrostatic
application to now adhere HA-ZnO composite. Patent #3 seems to be an attempt to secure a piece of
IP landscape in HA coatings and orthopaedic treatments. This is evident in APPENDIX B where the
yellow highlighted text derived from Patent #3 is vague in regards to application, composition and
topography of the HA coating, merely attempts to publish the idea of HA being applied to dental
implants with little evidence of HA supporting literature (US Patent No. US5873725A, 1999).
spray and in 2012 patented an innovation through the addition of ZnO, shows there is room to move
with other ‘body-excepting elements’ (i.e. MgO, CuO). Xia et al. (2018) has published extensive
literature on optimising the plasma spray technique (alternate application method) and recent work
by Hidalgo-Robatto, et al. (2018) incorporates copper and zinc with highlighted text taking from
of defining in patents. Possible cause is still testing for optimal HA adhesion and composition. There
is much reported literature on when deciding the optimal technique of applying a HA composite to
defined method must be established in-order to fully commit to patenting and commercialisation.
of living. Despite the many improvements to social living standards, APPENDIX D shows the 180
days associated with a dental implant and often reworking of implants several times throughout the
patient lifespan. Producing a high-strength coating for orthopaedic implants via a HA composite is
endure a robust environment, applying this to the field of dentistry. A field resistant to rivalry and
competitive nature of artificial intelligence, at least in the medium-long term. Applied using the
advances in plasma-spraying, optimised by Xia et al. (2018) via thermal conditioning to form rod like
nano-crystals. Composite would aim at incorporating silver (Ag) for the antibacterial properties
which could reduce teeth decay when implemented in a highly bio-active environment.
specific task checklist to fulfil. Once the final process goals have been reached, the ideal end-point is
Provisional Patent Application: protect the ideas whilst engaging potential funders, assuring to
include “patent pending” on the invention (only good for twelve months) > File Non-Provisional
Patent Application: complete description will be filed to the Patent and Trademark Office (PTO).
developmental pathway generated by nanoscience. This enables the strict control over processes to
continue generating advanced synthetic materials. New insight re-scoped to further characterise
biological systems to integrate the performance and functionality. Therefore, advanced materials
within the field, creating a cycle of public awareness, knowledge and presence. This becomes an
intangible form of marketing with an overall commercialisation goal to be a product considered and
evaluated through the three traditional approaches being: the income approach, the market approach
Item Description/Reasoning
Being productive in industry shows interaction that will lead to funding
Productivity
opportunities and additional resources for greater outputs
Allocating time and space during Stage 2 (Resource Allocation) for creating
Profile
and maintain public presence, attract quality staff and enhance reputation
patent formation and commercialisation, pre-allocate time and space in Stage 2 planning (Resource
Allocation) to manage the possibility of PTO denial (could require additional financial and technical
Identifier Description/Reasoning
Specialists in commercialising IP and distinguished technology transferor
Uniquest
from research and development phase to the commercial market place
However, engaging Uniquest or similar organisation is a last result, although highly regarded and
recommended within the field, percentage dividend contracted with Uniquest is 30% of earnings
Secondary strategy if dental implants denied, follows the mindset of continuing with a HA composite,
but applying it to a less pronounced field. Such as jewellery or manicures, both fields encounter
customers who cannot engage with the trends and services due to adverse reactions. Further analysis
would address the financial return of such venture, marketability holds in this suggested field.
outcomes, cohesive activities in addition to Table 1 that will boost collaboration and expected to raise
funding. Each of the five stages listed below are named across the top with each stage flowing into
objectives and/or expectations of that stage followed with a flow into activities and milestones
viable and marketable product that will meet the expectations and goals of Section 2.0, where
commercial sustainability rests in continued research and development with industry presents.
Hidalgo-Robatto, B., López-Álvarez, M., Azevedo, A., Dorado, J., Serra, J., Azevedo, F., &
González, P. (2018). Pulsed laser deposition of copper and zinc doped hydroxyapatite
Jiang, W., Sun, l., Nyandoto, G., & Malshe, A. (2008). Electrostatic Spray Deposition of
Xia, L., Xie, Y., Fang, B., Wang, X., & Lin, K. (2018). In situ modulation of crystallinity and nano-
orthopaedic applications. Patent #3 provided as an example paper seeking to own the landscape
Patent #1
Inventors
Fang Wu, Yi Huang, Lei Song, Xiaoguang Liu, Yanfeng Xiao, Jiamin Feng, Jiyong Chen
Title
Patent #2
Inventors
Title
Patent #3
Inventors
Title
that will meet the expectations and goals of Section 2.0, where commercial sustainability rests in
6. REFERENCES
Ecosphere Technologies. (2014). Independent Appraisal Report. Boston: IPV.
Hidalgo-Robatto, B., López-Álvarez, M., Azevedo, A., Dorado, J., Serra, J., Azevedo, F., &
González, P. (2018). Pulsed laser deposition of copper and zinc doped hydroxyapatite
Jiang, W., Sun, l., Nyandoto, G., & Malshe, A. (2008). Electrostatic Spray Deposition of
Xia, L., Xie, Y., Fang, B., Wang, X., & Lin, K. (2018). In situ modulation of crystallinity and nano-
Section 2.0, where commercial sustainability rests in continued research and development with
industry presents.
REFERENCES.
“The next step in the fabrication of the inventive dental post is the application of
with the invention, it is necessary that a strong bond be formed between the dental
post and the layer of hydroxyapatite. The same is insured by first putting the
substrate post through a cleaning regimen not unlike that used to clean metals
before the deposition of hydroxyapatite in, for example, the manufacture of a dental
implant. Generally, the techniques for the deposition of the ceramic hydroxyapatite
to metallic posts are the same as the techniques employed in the manufacture of
metallic dental implants. These techniques are well known in the art and form no
may be employed.”
will meet the expectations and goals of Section 2.0, where commercial sustainability rests in
7. REFERENCES
Ecosphere Technologies. (2014). Independent Appraisal Report. Boston: IPV.
Hidalgo-Robatto, B., López-Álvarez, M., Azevedo, A., Dorado, J., Serra, J., Azevedo, F., &
González, P. (2018). Pulsed laser deposition of copper and zinc doped hydroxyapatite
Jiang, W., Sun, l., Nyandoto, G., & Malshe, A. (2008). Electrostatic Spray Deposition of
Xia, L., Xie, Y., Fang, B., Wang, X., & Lin, K. (2018). In situ modulation of crystallinity and nano-
and goals of Section 2.0, where commercial sustainability rests in continued research and
REFERENCES.
Figure 2: Typical timeline for dental implant (Dental Implants Dublin, 2018)