This document provides guidelines for diagnosing and treating leptomeningeal metastases (LM), a condition where cancer spreads to the membranes surrounding the brain and spinal cord. It outlines the recommended workup, including physical exams, imaging tests, and cerebrospinal fluid analysis. Patients are classified as poor or good risk based on factors like performance status and neurological deficits. Treatment options range from radiation therapy and supportive care for poor risk patients to radiation, clinical trials, and systemic therapies for good risk patients.
This document provides guidelines for diagnosing and treating leptomeningeal metastases (LM), a condition where cancer spreads to the membranes surrounding the brain and spinal cord. It outl…