Application for Cell Segmentation in Biological Research Yeast Cell One of the primary methods through which information is acquired from biological experiments is by optical Department 18 microscope imagery. A common Electrical Engineering and Information Technology bottleneck to scientific analysis is the Institute for segmentation of cells or regions of Telecommunications interest. Accurate determination of cell Bioinspired contours is an important step in Communication Systems quantifying morphological features as www.bcs.tu-darmstadt.de well as cell fluorescence intensity. A Prof. Dr. Heinz Koeppl convolutional neural network (U-net) is to be adapted to segment individual cells. Tim Prangemeier
Recently a range of machine tim.prangemeier@bcs.tu-
darmstadt.de learning techniques have been 06151 16 20886
applied to such data, however,
all of these still have some Christian Wildner drawbacks. This is in particular (christian.wildner@bcs.tu-
the case when cell trap darmstadt.de,
+49 06151 16 51240) structures are included on the images (Fig. 1). The use of convolutional neural networks Figure 1: Microscope image of promises accurate segmentation yeast cells (green) immobilised in microscopic trap structures with relatively small training (grey) [bottom], with Thesis Topic (B.Sc. / M.Sc.) data sets. conventionally segmented cell contour (red) [top]. • Machine Learning • Image Processing • Automation Contact Tim Prangemeier (tim.prangemeier@bcs.tu-darmstadt.de, • Cell Segmentation +49 6151 16 20886),or Christian Wildner • Supervised Learning (christian.wildner@bcs.tu-darmstadt.de, • Bio-application
+49 06151 16 51240) for further information on this topic.