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  • Proiotics

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    Wobik Hope
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    A case study titled “Probiotics for Kidney Health Gut‐Based Uremic Toxin Removal – “Enteric Dialysis™” was presented by Kibow at the 5th Asian Conference on Lactic Acid Bacteria Microbes in Disease Prevention, Singapore. The case study talks about the effectiveness of the probiotics in curbing the uremic toxins that plague the body’s health. The case study talks about Uremic toxins and how its growth can cause severe health problems like Chronic Kidney Disease and Inflammation. The case study follows up a cycle of various experiments and its related outcomes in each subsequent stages.

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    A case study titled “Probiotics for Kidney Health Gut‐Based Uremic Toxin Removal – “Enteric Dialysis™” was presented by Kibow at the 5th Asian Conference on Lactic Acid Bacteria Microbes in Disease Prevention, Singapore. The case study talks about the effectiveness of the probiotics in curbing the uremic toxins that plague the body’s health. The case study talks about Uremic toxins and how its growth can cause severe health problems like Chronic Kidney Disease and Inflammation. The case study follows up a cycle of various experiments and its related outcomes in each subsequent stages.

    Droits d'auteur :

    © All Rights Reserved
    Signaler comme contenu inapproprié
    17 vues1 page

    Proiotics

    Transféré par

    Wobik Hope
    A case study titled “Probiotics for Kidney Health Gut‐Based Uremic Toxin Removal – “Enteric Dialysis™” was presented by Kibow at the 5th Asian Conference on Lactic Acid Bacteria Microbes in Disease Prevention, Singapore. The case study talks about the effectiveness of the probiotics in curbing the uremic toxins that plague the body’s health. The case study talks about Uremic toxins and how its growth can cause severe health problems like Chronic Kidney Disease and Inflammation. The case study follows up a cycle of various experiments and its related outcomes in each subsequent stages.

    Droits d'auteur :

    © All Rights Reserved
    Signaler comme contenu inapproprié
    sur 1

    Probiotics for Kidney Health The 5th Asian Conference on Lactic Acid Bacteria

    Gut‐Based Uremic Toxin Removal – “Enteric Dialysis™” Microbes in Disease Prevention


    Natarajan Ranganathan, Ph.D.  Kibow Biotech Inc., Newtown Square, PA 1st to 3rd July 2009, Singapore
    Eli A. Friedman, M.D.  State University of New York, Brooklyn, NY

    Kibow Biotics SHIME Studies 5/6th Nephrectomized  5/6th


    S.T  (KB 19) Nephrectomized  Phase I Safety 
    Gut‐flora  Rat Studies
    L.A (KB 27) Mini‐pig Trials Trials
    Adaptation  Thomas Jefferson 
    B.L (KB 31) Indiana  Science Center, 
    Studies University, 
    Exhaustive  In  University, IN Philadelphia, PA
    Ghent, Belgium Philadelphia PA
    Vitro Studies

    Human Trials in  Veterinary  Positive Results 


    Preliminary data  Canada, USA,  Online Veterinary 
    Licensing to  from Live Kidney 
    from Canadian  Nigeria, and  Product Sales 
    Vètoquinol Failure Cats and 
    clinical studies  Argentina (2007) Initiated
    EU ,July 2006 Dogs
    site (Almost Complete)

    Study Design: 6 months Double Blind Placebo Controlled Cross‐over (after 3 months) 
    Inclusion Criteria: CKD Stages III and IV, Scr > 2.5mg/ml, 18‐75 yrs old 
    Study Site: Corp Med Ctr, Scarborough Hospital, Ontario, Canada. 
    Primary Endpoints: Biochemical (Urea, Creatinine, Uric acid) and CRP 
    Secondary Endpoints: Fecal Analysis and Quality of Life. 
    Results: 13 patients complete study. 
    Ave mean change: BUN: 4.52 mmol/L (placebo), ‐2.95mmol/L (KB), P = 0.002; 
    Uric acid: 50.62 µmol/L (placebo),  24.70 µmol/L (KB), P = 0.05, Scr: Stable, 
    CRP levels: Slightly lower, 
    Positive fecal changes observed with improved QOL (P = 0.05)

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