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AMENORRHEA
For a female who has not undergone fertilization, the following occurs:
o Corpus luteum involutes
o No estrogen and progesterone that keep the endometrium
intact
o Shedding of endometrial lining; thus, menstruation occurs
For a female who has undergone fertilization, the following occurs:
o Formation of Zygote
o Implantation into endometrium as blastocyst
o Trophoblast secretes hCG (Mimics action of LH)
o Corpus luteum still secretes Estrogen and Progesterone
o prevents sloughing off of the endometrium
o No menstruation occurs
MENOPAUSE
↑ FSH - No more negative feedback mechanism from the estrogen →
no
inhibition of FSH
↓ Estradiol - Follicle is no longer released → ovulation no longer occurs →
corpus luteum will no longer produce estrogen
Types of estrogen:
o E1: Estrone – predominant estrogen during menopause
o E2: Estradiol – predominant estrogen during reproductive
o age
o E3: Estriol – predominant estrogen during pregnancy