PATHOPHYSIOLOGY

Contributing factor: Predisposing factor:

- Bacteria - Age

Staphylococcus pneumoniae

Organism enter to the respiratory tract through inhalation/ aspiration

Penetrate the sterile lower respiratory tract (lungs)

Bacteria multiplies

Irritation of airway

Activation of defense mechanism

Increase goblet cells (increase mucus production),

Occlusion of airway that could lead to

Impaired oxygen and carbon dioxide exchange ventilatory demands and airway constriction

Cough, crackles, (difficulty of breathing), hyperventilate (increased respiratory)

Further Invasion of bacteria inside the lungs would further cause

Release of damaging toxins(infection)

 Inflammation

Exudates come from bacteria erode the lung

Dead space happened

Decrease oxygen

Lung consolidation

Hypoxia