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DOI 10.1007/s00769-008-0475-6
PRACTITIONER’S REPORT
Received: 5 May 2008 / Accepted: 21 November 2008 / Published online: 19 December 2008
Springer-Verlag 2008
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96 Accred Qual Assur (2009) 14:95–106
based on the mathematical combination of probability MCM in a general purpose mathematical program is not
distribution (by means of the law of propagation of complex and allows control over all of its possibilities.
uncertainty and the central limit theorem), while the MCM Similarly, some specific programs are beginning to
is a probabilistic method that performs the combination of implement the adaptive MCM [25].
probability distributions by numerical simulation (through From among the commercial mathematical analysis
calculation systems for generating random numbers). software applications, MATLAB is widely distributed
GUF is based on the law of propagation of uncertainty worldwide and is widely used in universities as well as by
and on the characterization of the quantities measured by all kinds of professionals. As of version 7.4, it uses the
means of either a normal (Gaussian) distribution or a Mersenne Twister algorithm [26] for generating pseudo-
t-distribution, which allows measurement uncertainty to random numbers, which has passed numerous randomness
be delimited by means of a confidence interval. Unfor- tests, among them the strict Diehard test [27]. MATLAB
tunately, to determine this confidence interval, GUF may was the software used in developing the examples in sup-
only be applied if two conditions are met: firstly, lineal plement 1 to the GUM. This article explains the basic
dependence must exist between the measurand and the implementation of the adaptive Monte Carlo method in
arguments of the measurement process; and secondly, in MATLAB, which may be used in other similar programs
most cases it must be justifiable the application of the with each program’s variations.
central limit theorem. In order to be able to apply the
method, if the mathematical model is not linear, it is
linearized based on the first order Taylor series approxi- GUF and MCM
mation; however, not complying with either of the two
mentioned conditions may lead to an inadequate repre- A measurand, denoted by Y, is a quantity subject to mea-
sentation and, therefore, to confidence intervals for surement. An estimate for Y, denoted by y, is a central
uncertainty that are hardly reliable [4]. value of the distribution of values that could be reasonably
MCM is an alternative to GUF. MCM performs a be attributed to Y. The uncertainty is a parameter associated
characterization of the quantities measured based on the with the estimate y which characterizes the dispersion of
random sampling of the probability distribution functions. the values that could be attributed to Y based upon all
This numerical simulation tends to require around 106 trials available information. The standard uncertainty is uncer-
(model evaluations), which require a computer. Since the tainty expressed as a standard deviation, denoted by u(y).
domain of validity for MCM is broader than that for the Methods used for evaluation of measurement uncertainties
GUF, MCM can be applied in all those situations in which are based on the concept of a measurement equation:
the conditions for applying GUF are not met or are not
Y ¼ f ðX1 ; X2 ; . . .; XN Þ ð1Þ
clear. An important aspect to bear in mind is that the MCM
can be used to determine whether all the conditions for The input quantities Xi are all those that have an
applying GUF hold. influence on the result of the measurement, including
There are software applications that are specifically correction factors as well as quantities that take into account
developed for calculating measurement uncertainties [5–7], other variability sources. The output quantity is the
some of which use the MCM, such as WINCERT [8], measurand Y. Given that its values are not known with
Evaluator [9], MUSE [10] or UncertaintyManager [11]. absolute certainty, all the quantities involved are considered
Other software applications meant for statistical systems random variables. Each one of them is characterized by its
and risk analysis can also be used for uncertainty calcula- probability density function, the mathematical expectation
tions, such as Minitab [12], LabVIEW [13], Analytica [14] of which is the estimate of the quantity value and the
or Microsoft Excel @Risk [15] and Crystal Ball [16] add- standard deviation of which is the standard uncertainty
ins. In addition, it is easy to implement the MCM in general related to the estimate.
purpose mathematical programs such as MATLAB [17], The fundamental difference between GUF and MCM
MathCad [18], Mathematica [19], Maple [20], etc. lies in the way they characterize the output quantity. GUF
The examples developed with both the specific pro- determines, from the standard uncertainties of the input
grams and those used for risk and system analysis [21–23] quantities, what will be the standard uncertainty for the
have not been able to apply the MCM in an adaptive way; output quantity; and, to delimit measurement uncertainty
simply choosing the number of iterations to perform by means of a confidence interval, characterizes the output
beforehand or, at the most, performing a preliminary study quantity by means of either a normal (Gaussian) distribu-
to determine the adequate number of them [24]. If the tion or a t-distribution. MCM obtains, from the probability
MCM is not adaptive, there is no direct control over the distributions of the input quantities, an approximate
quality of the results obtained. The implementation of the numerical representation of the probability distribution for
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Accred Qual Assur (2009) 14:95–106 97
the output quantity. GUF propagates the standard uncer- that this practice is followed, the degrees of freedom of
tainties and MCM propagates the probability distributions. the standard uncertainty uB(xi) obtained from a Type B
GUF performs the propagation of standard uncertainties evaluation may be taken to be mi ? ?.
using the so called ‘‘law of propagation of uncertainty’’
If the probability distribution of the output quantity were
which is, simply, the expression of the standard deviation
normal, the interval defined by its standard uncertainty u(y)
of a linear combination of random variables. The func-
would have a level of confidence or coverage probability of
tional relation between the output quantity Y and the input
approximately 68%. Since, in general, this is required to be
quantities Xi must be linearized by approximating it
95 or 99%, the uncertainty interval is usually expressed
through the first order terms of the Taylor series in a
through the expanded uncertainty, which is simply the
neighborhood of its estimates xi, denoted by a lower case
standard uncertainty multiplied by a coverage factor ky:
letter:
U ð y Þ ¼ k y uð y Þ ð5Þ
X
N
Y ¼ f ðX1 ; X2 ; . . .; XN Þ ’ yðx1 ; x2 ; . . .; xN Þ þ ci X i ð2Þ For normal distribution, a value ky = 2 corresponds to
i¼1
an approximate coverage probability of 95%, and ky = 3 of
where the coefficients ci are known as sensitivity 99%. In many practical cases, the conditions of the central
coefficients: limit theorem are met and the probability distribution of the
output quantity is close to normal, but not completely since
of ðX1 ; X2 ; . . .; XN Þ
ci ¼ ð3Þ its standard deviation has been estimated. Its probability
oX i x1 ;x2 ;...;xN
distribution is then a t-distribution, the effective degrees of
Once linearized, it is possible to use the law of freedom meff of which may be calculated from the degrees
propagation of uncertainty: of freedom considered for the input estimates mi by means
vffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffi of the Welch-Satterthwaite formula:
u N
uX N 1 X
X N
uð y Þ ¼ t c2i u2 ðxi Þ þ 2 ci cj u xi ; xj ð4Þ u4 ð y Þ
meff ¼ P ð6Þ
i¼1 i¼1 j¼iþ1 N c4i u4 ðxi Þ
i¼1 mi
In this expression, u(xi) are the standard uncertainties
Knowing that the probability distribution is a t-
related to the input estimates, and u(xi, xj) are the possible
distribution with meff degrees of freedom, it is possible to
covariances between them.
determine the coverage factor ky for the desired level of
The input variables may be evaluated from statistical
confidence.
methods or determined by other means. An input variable
An alternative to this approximate t-distribution based
is referred to as Type A or Type B depending on whether
on the Welch-Satterthwaite formula is the use of the
its probability distribution or its parameters are specified by
Bayesian extension [27]. The assumptions that underlie
statistical methods or by other means:
both methods are essentially identical. Nevertheless, the
• In a Type A evaluation of an input quantity Xi, the use of the Bayesian extension greatly simplifies the
estimate xi and the uncertainty uA(xi) are determined expression of uncertainty by eliminating altogether
from sampling theory (the subscript A indicates that it is a the need for calculating effective degrees of freedom from
Type A standard uncertainty). Depending on the number the Welch-Satterthwaite formula.
mi of independent measurements, the Type A standard MCM carries out the propagation of probability distri-
uncertainty is uncertain because of the statistical reason butions sampling the probability distribution of the output
of limited sampling. Following the ISO-GUM, the quantity Y. In this method, probability density functions
statistical uncertainty concerning uA(xi) is quantified by (PDF) are explicitly assigned to all input quantities Xi
degrees of freedom. The degrees of freedom associated based on information concerning these quantities. GUM
with uA(xi) are mi = mi - 1. Supplement 1 [3] gives guidance on the assignment, in
• A Type B evaluation of an input quantity Xi is some common circumstances, of PDFs to the input quan-
commonly obtained by assigning a state-of-knowledge tities Xi. In order to construct a PDF for a quantity, on the
probability distribution for Xi. Then, the estimate xi is basis of a series of indications, Bayes’ theorem can be
the expected value E(Xi) and the standard uncertainty applied. When appropriate information is available con-
uB(xi) is the standard deviation S(Xi) of the assigned cerning systematic effects, the principle of maximum
distribution (the subscript B indicates that it is a Type B entropy can be used to assign a suitable PDF. The GUM
standard uncertainty). It is common practice to carry Supplement 1 does not distinguish between the Types A
out a Type B evaluation in a manner that ensures that and B state-of-knowledge probability distributions for the
any underestimation is avoided. Under the assumption input variables. Nevertheless, this classification is still
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98 Accred Qual Assur (2009) 14:95–106
important [28] since the information the metrologist have (a) Choose the desired coverage probability p for the
for quantities of Type A or Type B is very different (sta- interval to be obtained.
tistical analysis or other means, respectively). Each value yr (b) Choose the number of significant decimal digits ndig for
(r = 1,…, M) is obtained by performing a random sam- the uncertainty u(y). It is normal to take a value of 1 or 2.
pling of each of the probability density functions of the (c) Choose the number M of trials to perform in each
input quantities Xi and evaluating the model with the values sequence of the application of the process. Standard
found. The M values of Y thus obtained must be arranged in practice is to make:
a non-decreasing order, thus providing an approximate
M ¼ max 100 ð1 pÞ 104 : ð7Þ
numerical representation G of its distribution function
GY(g). This vector G can be used to obtain an estimate y of These two values have been intentionally chosen to be
Y, the standard uncertainty u(y) related to y, as well as an much smaller than the foreseeable total number of
appropriate coverage interval for Y, for a stipulated cov- iterations (of the order of 106) in order to be able to
erage probability p. The effectiveness of MCM in obtaining analyze, after every sequence, the variability of the
y, u(y) and a coverage interval for Y depend on the statistics of the parameters to be determined. In addi-
appropriate choice of a sufficiently large M value. tion, this value M is taken as a multiple of 1/1(1 - p)
The conditions for a valid application of MCM are less in order to help in the determination of the shortest
restrictive than those of GUF. However, MCM is very coverage interval (104 is a multiple of 1/1(1 - p) for
difficult to use in some cases, for example when the input the usual cases in which p = 0.95 and 0.99).
quantities are correlated. The use of both methods leads to (d) The variable h counts the number of MC-simulations.
a better understanding of the measurement process. In order to carry out the first one, h = 1 is
established.
(e) For each h sequence, M trials or evaluations of the
The adaptive Monte Carlo method model are carried out, which gives the values yr
(r = 1,…, M) and the following estimated parameters:
A fundamental parameter in order to obtain reliable results
• Average is taken as an estimate y of Y:
through MCM is the number M of trials or evaluations to
be performed by the model. If M is chosen beforehand, 1X M
yðhÞ ¼ yr ð8Þ
there will not be direct control over the results. A value M r¼1
M = 106 is often considered appropriate in order to pro-
vide a coverage interval of 95%; however, the random • Standard deviation is taken as the standard
nature of the process and the nature of the probability uncertainty u(y) associated with y:
vffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffi
distribution of the output quantity Y have an influence on u u 1 X M
the value needed for M, which will vary in each case. For u yðhÞ ¼ t ðy r y Þ2 ð9Þ
this reason, the performance of the MCM must be carried M 1 r¼1
out in an adaptive way, progressively increasing the
number of iterations until the stabilization of the results. • Let q the integer part of pM ? 1/2. Sorting the
The stabilization criterion for the results is established values yr (r = 1,…, M) in a non-decreasing order
in accordance with the aim of arriving at a given y(r) (r = 1,…, M), the probabilistically symmetric
ðhÞ ðhÞ
numerical tolerance. The numerical tolerance d is defined coverage interval for Y will be [ylow ; yhigh ]. The
as the semi-width of the shortest interval containing all ðhÞ ðhÞ
interval extremes are ylow ¼ yðrÞ and yhigh ¼ yðrþqÞ ;
numbers that can be expressed to a specified number of
where r is the integer part of (M - q)/2 ? 1/2. If
significant decimal digits. For example, the numerical
the desired result is the shortest coverage interval,
tolerance associated with the numerical value 2.3 is
the value r* should be determined such that
d = 0.05, as that number can express any value included
yðr þqÞ yðr Þ yðrþqÞ yðrÞ for each and everyone
between 2.25 and 2.35. In supplement 1 to the GUM the
results stabilization criterion is the following: a numerical of the values r = 1,…, (M - q).
result is deemed to have stabilized in a statistical sense (f) In order to analyze the variability of the parameters,
when twice the standard deviation associated with it is more than one sequence is required, thus if h = 1, it
less than the numerical tolerance associated with the should be increased by one unit and return to step (e).
standard uncertainty u(y). (g) After every sequence, the average and standard
The calculation algorithm of the flexible MCM com- deviation of these latter parameters must be
prises the following steps: calculated:
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Accred Qual Assur (2009) 14:95–106 99
• For the estimate: u(y) have already been calculated in steps (g) and (h),
respectively.
1X h
y^ ¼ y ¼ yðiÞ ð10Þ
h i¼1
vffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffi
u Programming in MATLAB
u 1 X h
sy^ ¼ t
2
ðyðiÞ y^Þ ð11Þ
hðh 1Þ i¼1 MATLAB is software developed for performing numerical
calculations with vectors and matrices. The programming
• For the standard uncertainty: language used constitutes a high level tool that is very fast
1X h against other application development environments. A
u^ð yÞ ¼ u yðiÞ ð12Þ program in MATLAB, as in any programming language,
h i¼1
vffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffi consists of a series of instructions that run sequentially,
u with the possibility of containing certain instructions that
u 1 X h
su^ðyÞ ¼ t
2
ðuðyðiÞ Þ u^ð yÞÞ ð13Þ control those which will run in each circumstance. Creating
hðh 1Þ i¼1 a program in MATLAB is simple: just open a text docu-
ment (it can be done in any editor, if there is one built in),
• For the lowest extreme of the coverage interval:
write the instructions as they would be entered into the
1X h
ð iÞ command window and save the document with the exten-
y^low ¼ y ð14Þ sion.m. MATLAB automatically recognizes files with this
h i¼1 low
vffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffi extension. In addition, it contains a set of tools called
u h 2 ‘‘user interface’’ that allow giving the programs made
u 1 X
¼t
ðiÞ
sy^low ylow y^low ð15Þ with it a user-friendly appearance, similar to a Windows
hðh 1Þ i¼1
application.
Implementation of the Monte Carlo method in
• For the highest extreme of the coverage interval:
MATLAB, according to the algorithm described in the
1X h
ðiÞ previous section, requires the user to enter a series of
y^high ¼ y ð16Þ
h i¼1 high information: the functional relation of the measurement
vffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffi process, the probability distributions of the input quantities,
u h 2
u 1 X their parameters, the required coverage probability, whe-
¼t
ð iÞ
sy^high yhigh y^high ð17Þ ther the coverage interval being sought is probabilistically
hðh 1Þ i¼1
symmetrical or the shortest, and the number of significant
(h) In order to apply the stabilization criterion to the decimal digits for the standard uncertainty. User interaction
results, the numerical tolerance d related to the with the developed program can take place through ‘‘user
standard uncertainty u(y) must be calculated. The interface’’ instructions, which allows buttons, menus,
uncertainty u(y) is calculated as in step (e), but using all windows, to be created, etc.; however, in order not to
the values h 9 M of the model. The tolerance is simply excessively complicate the program and thus make it more
half of the last significant digit of the uncertainty. For understandable, they will not be used and information will
its computer calculation, the uncertainty must be be directly entered in the first lines of the program.
expressed in the form u(y) = c 9 10d, where c is an Table 1 details the program developed for the calcula-
ndig decimal digit integer and d an integer; then, the tion of uncertainty in the calibration of a mass. For any
related numerical tolerance is: other case, it is enough to modify the first lines, since they
are the ones that establish the variables that are charac-
1 teristic of each case:
d ¼ 10d ð18Þ
2 • In line 2, the coverage probability p is specified, the
(i) The stabilization criterion for the results establishes number of significant decimal digits for the standard
that if any of the values of 2sy^; 2su^ðyÞ ; 2sy^low or 2sy^high uncertainty n_digit, (normally 1 or 2) and a value called
are greater than d, h should be increased by one unit tol_divisor that divides the numerical tolerance. This
and step (e) should be repeated. value is entered in order to take into account recom-
(j) Once the stabilization criterion has been verified, all mendation [3], which states that when MCM is used to
the values h 9 M of the model should be used to validate GUF, a numerical tolerance five times less than
calculate ylow and yhigh in the same way that it was that related to the standard uncertainty is taken in the
done in step (e) for each sequence. The values of y and application of the stabilization criterion.
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100 Accred Qual Assur (2009) 14:95–106
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Accred Qual Assur (2009) 14:95–106 101
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102 Accred Qual Assur (2009) 14:95–106
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Accred Qual Assur (2009) 14:95–106 103
against grade I gauge block of steel. The example concerns • The average thermal expansion coefficient is
the 150 mm calibration point for measurement of external a ¼ 11:5 106 C1 . Its uncertainty is considered
dimensions. The error of the indication Ex of the calliper at negligible for the present case.
the reference temperature t0 = 20 C is obtained from the • After an adequate stabilisation time, the temperatures
relation: of the calliper and the gauge block are equal within
Ex ¼ lix ls þ Ls
a Dt þ dlix þ dlM ð24Þ ±2 C. A rectangular distribution can be assigned to
this quantity Dt, with said limit values as extremes of
where lix is the indication of the calliper, ls the length of the the distribution.
gauge block, Ls the nominal length of the gauge block, a • The scale interval of the Vernier scale is 0.05 mm.
the average thermal expansion coefficient of the calliper Thus, variations dlix due to the finite resolution are
and the gauge block, Dt the difference in temperature estimated to have rectangular limits of ±25 lm.
between the calliper and the gauge block, dlix the correc- • Mechanical effects dlM include the applied measure-
tion due to the finite resolution of the calliper and dlM the ment force, the Abbe error and the play between the
correction due to mechanical effects. beam and the sliding jaw. Additional effects may be
The information on each of the input quantities is used caused by the fact that the measuring faces of the jaws
to assign a probability distribution to them: are not exactly flat, not parallel to each other and not
• The result of measurement for the 150 mm gauge block perpendicular to the beam. To minimize effort, only the
is lix = 150.10 mm. The measurement is repeated range of the total variation, equal to ±25 lm is
several times without detecting any scatter in the considered as interval of variability of a rectangular
observations. Thus, uncertainty due to limited repeat- distribution.
ability does not give a contribution. From this data, it is possible to use GUF as well as
• The length of the reference gauge block used as working MCM to obtain ^
an estimate Ex of Ex, its related standard
standard, together with its associated expanded uncer- uncertainty u E^x , and the shortest 95% coverage interval.
tainty of measurement, is given in the calibration None of the input quantities are considered to be correlated
certificate. This certificate confirms that the gauge block to any significant extent. The GUF and the adaptive MCM
comply with the requirements for grade I gauge blocks were each used (a high number of significant figures have
according to ISO 3650, i.e. that the central length ls of the been taken for comparison purposes only):
gauge block coincides within ± 0.8 lm with the nom-
inal length Ls = 150 mm. A rectangular distribution can • GUF method (Table 5) gives the estimate E^x ¼
be assigned to the quantity ls, taking the tolerance limits 0:1000
mm and associated standard uncertainty
as the upper and lower limits of the interval of variability. u E^x ¼ 0:0323 mm. A probabilistically symmetric
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104 Accred Qual Assur (2009) 14:95–106
Table 6 First lines of the MATLAB program for the calibration of a Vernier calliper
(and shortest) 95% coverage interval for Ex, based on a parameters obtained from GUF has been superimposed
coverage factor of 1.96 for the Gaussian probability (continuous curve named GUFG). It can be seen how the
density function, is [0.0366, 0.1634]mm. probability density functions obtained by both methods
• To carry out the adaptive MCM, the first lines of the differ significantly.
program must be modified (Table 6). Running the The trapezoidal-shaped probability density function
program, this time for n_digit = 2, it performed obtained by MCM and the uncertainty budget show that
6.74 9 106 evaluations of the model until the stabil- the uncertainty of measurement associated with the result
ization of the results in 5 min. It gives the estimate is clearly dominated by two influences: the mechanical
E^x ¼0:1000 mm with associated standard uncertainty effects and the finite resolution of the Vernier scale.
u E^x ¼ 0:0323 mm and a shortest 95% coverage Thus, the assumption of a normal distribution for the
interval [0.0409, 0.1595]mm. output quantity is not justified. If the two dominant
contributions arise from rectangular distributions, the final
The results show that GUF and MCM give estimates and
distribution would be essentially trapezoidal. The distri-
associated standard uncertainties in good agreement, but
bution resulting of convolving the two rectangular
there are differences in the coverage intervals. Figure 2
distributions associated with the dominant contributions is
represents the histogram generates by the MATLAB pro-
a symmetrical trapezoidal distribution (broken curve
gram, onto which the curve of a Gaussian distribution of
named GUFT in Fig. 2). The half-widths of the base and
the top of the resulting symmetrical trapezoid are 75 and
25 lm, respectively. Ninety-five percentage of the area of
the trapezoid is encompassed by an interval ±60 lm
around its symmetric axes, corresponding to a coverage
factor of 1.83 [30, p. 62]. If this trapezoidal distribution
is taken into account in the GUF evaluation of the
uncertainty, it gives a shortest 95% coverage interval
[0.0408, 0.1592]mm.
Table 7 expresses the results obtained with each of the
methods, as well as its comparison in order to validate the
application of GUF. For a numerical tolerance of two
significant decimal digits in u(y) (d = 0.0005), the vali-
dation of GUF is positive only if a trapezoidal probability
distribution is assumed. In this case, the 95% coverage
interval is [0.041, 0.159]mm. For a numerical tolerance of
one significant decimal digit in u(y) (d = 0.005), the val-
Fig. 2 Approximation of the probability density function for the
idation status would be positive in both cases, Gaussian or
output quantity using GUF, with Gaussian or trapezoidal distribution, trapezoidal probability distribution, and the 95% coverage
and MCM interval would be [0.04, 0.16]mm.
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Accred Qual Assur (2009) 14:95–106 105
Table 7 Results of the calculation stage in the calibration of a Vernier calliper using GUF method, with Gaussian or trapezoidal distribution, and
MCM
Method dE^x u dE^x (mm) Shortest 95% cove-rage dlow (mm) dhigh (mm) GUF validated GUF validated
(mm) interval (mm) (d = 0.0005)? (d = 0.005)?
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106 Accred Qual Assur (2009) 14:95–106
24. Canaves M Jr, Pompèia PJ (2006) Uncertainty of the density of 28. Kacker RN (2006) Bayesian alternative to the ISO-GUM’s use of
moist air: Gum 9 Monte Carlo. Braz Arch Biol Technol 49:87–95 the Welch-Satterthwaite formula. Metrologia 43:1–11. doi:
25. Müller M, Wolf M, Rösslein M (2008) MUSE: computational 10.1088/0026-1394/43/1/001
aspects of a GUM supplement 1 implementation. Metrologia 29. Kacker RN, Toman B, Huang D (2006) Comparison of ISO-
45:586–594. doi:10.1088/0026-1394/45/5/013 GUM, draft GUM Supplement 1 and Bayesian statistics using
26. Matsumoto M, Nishimura T (1998) Mersenne Twister: a 623- simple linear calibration. Metrologia 43:167–177. doi:10.1088/
dimensionally equidistributed uniform pseudo-random number 0026-1394/43/4/S02
generator. ACM Trans Model Comput Simul 8:3–30. doi: 30. EA4 02 Expression of the Uncertainty of Measurement in Cali-
10.1145/272991.272995 bration (1999) European Cooperation for Accreditation
27. Marsaglia G (1995) The Diehard battery of tests of randomness, 31. Group of Structural Integrity (GIE Grupo de Integridad Estruc-
CDROM (Supercomputer Computations Research Institute and tural), Universidad de Burgos. http://web.ubu.es/investig/grupos/
Department of Statistics, Florida State University, Florida) ing_const/mmc-2/enlaces.html. Accessed 14 Nov 2008
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