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1) The force driving simple diffusion is ________, while the energy source for active transport is
________.
A) the concentration gradient; ADP
B) the concentration gradient; ATP
C) transmembrane pumps; electron transport
D) phosphorylated protein carriers; ATP
4) Like other osmoregulatory animals that live in marine environments, sharks maintain tissue
concentrations of sodium, potassium, and chloride that are hypoosmotic to the seawater. In
contrast to the bony marine fishes, however, sharks do not need to drink seawater. Why?
A) High urea and trimethylamine oxide concentrations keep shark tissues slightly hyperosmotic
relative to seawater, so water is absorbed passively.
B) Sodium, chloride, and potassium do not influence water balance in shark tissues.
C) Shark blood is hypotonic to the surrounding tissues, so water always moves passively into the
tissue from the blood.
D) Sharks excrete large quantities of salt through their gills in exchange for water
5) What role do transport epithelia play in osmoregulation of marine fish with bony skeletons?
A) They actively transport salt into the animal through the gills.
B) They mediate the movement of water from seawater through the gills.
C) They are involved in excretion of excess salt.
D) They allow the fish to produce dilute urine.
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6) Salmon eggs hatch in fresh water. The fish then migrate to the ocean (a hypertonic solution)
and, after several years of feeding and growing, return to fresh water to breed. How can these
organisms make the transition from fresh water to ocean water and back to fresh water?
A) The rectal gland functions in the ocean water, and chloride cells function in fresh water.
B) The salt transport mechanisms of the gill epithelia change during migration.
C) Salmon in fresh water excrete concentrated urine, and salmon in salt water secrete dilute
urine.
D) Their metabolism changes in salt water to degrade electrolytes.
8) An examination of a marine sea star that had died after it was mistakenly placed in fresh water
would likely show that it died because ________.
A) it was stressed and needed more time to acclimate to the new conditions
B) it was so hypertonic to the fresh water that it could not osmoregulate
C) its kidney had ruptured
D) its cells dehydrated and lost the ability to metabolize
9) The body fluids of an osmoconformer would be ________ with its ________ environment
A) hyperosmotic; freshwater
B) hyperosmotic; seawater
C) isoosmotic; seawater
D) hypoosmotic; seawater
10) Compared to the seawater around them, most marine invertebrates are ________.
A) hyperosmotic
B) hypoosmotic
C) isoosmotic
D) both hyperosmotic and isoosmotic
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12) Unlike most bony fishes, sharks maintain body fluids that are isoosmotic to seawater, so they
are considered by many to be osmoconformers. Nonetheless, these sharks osmoregulate at least
partially by ________.
A) using their gills and kidneys to rid themselves of sea salts
B) monitoring dehydration at the cellular level with special gated aquaporins
C) tolerating high urea concentrations that are balanced with internal salt concentrations to
seawater osmolarity
D) synthesizing trimethylamine oxide, a chemical that binds and precipitates salts inside cells
13) An examination of a freshwater fish that died after being placed accidentally in saltwater
would likely show that ________.
A) loss of water by osmosis from cells in vital organs resulted in cell death and organ failure
B) high amounts of salt had diffused into the fish's cells, causing them to swell and lyse
C) the kidneys were not able to keep up with the water removal necessary in this hyperosmotic
environment, creating an irrevocable loss of homeostasis
D) the gills became encrusted with salt, resulting in inadequate gas exchange and a resulting
asphyxiation
14) Animals have adapted different mechanisms for excreting nitrogenous waste products.
Which of the following are selective pressures that likely influence which mechanism an animal
uses?
I) the amount of water available in the animal's habitat
II) the energy needs of the animal
III) the temperature of the animal's environment
A) only I and III
B) only II and III
C) only I and II
D) I, II, and III
17) Which nitrogenous waste has the greatest number of nitrogen atoms?
A) ammonia
B) ammonium ions
C) urea
D) uric acid
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18) Ammonia is likely to be the primary nitrogenous waste in living conditions that include
________.
A) lots of fresh water flowing across the gills of a fish
B) lots of seawater, such as a bird living in a marine environment
C) a terrestrial environment, such as that supporting crickets
D) a moist system of burrows, such as those of naked mole rats
20) Developing bird embryos excrete most of their nitrogenous waste as uric acid because
________.
A) it is less metabolically expensive to produce compared to other waste products
B) it has a low solubility in water and is less toxic to the embryo than other forms of waste
C) it requires less energy to transport across the egg shell
D) it can be recycled by the embryo to make new protein
21) The advantage of excreting nitrogenous wastes as urea rather than as ammonia is that
________.
A) urea can be removed as a semi-solid paste
B) urea is less toxic than ammonia
C) urea does not affect the osmotic gradient
D) less nitrogen is removed from the body
22) In animals, nitrogenous wastes are produced mostly from the catabolism of ________.
A) starch and cellulose
B) triglycerides and steroids
C) proteins and nucleic acids
D) phospholipids and glycolipids
23) Birds secrete uric acid as their nitrogenous waste because uric acid ________.
A) is readily soluble in water
B) is metabolically less expensive to synthesize than other excretory products
C) requires little water for nitrogenous waste disposal, thus reducing body mass
D) can be reused by birds as a protein source
24) Among the following choices, the most concentrated urine is excreted by ________.
A) frogs
B) kangaroo rats
C) humans
D) freshwater bass
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25) African lungfish, which are often found in small, stagnant pools of fresh water, produce urea
as a nitrogenous waste. What is the advantage of this adaptation?
A) Urea takes less energy to synthesize than ammonia.
B) Small, stagnant pools do not provide enough water to dilute the toxic ammonia.
C) The highly toxic urea makes the pool uninhabitable to potential competitors.
D) Urea makes lungfish tissue hypoosmotic to the pool.
26) Studies of cricket Malpighian tubules revealed that potassium ions accumulated inside the
tubule, moving against the potassium concentration gradient. Based on the information, what can
you infer about the mechanism of potassium transport?
A) Potassium transport is a passive process.
B) Movement of potassium into the lumen of the Malpighian tubules is an energy-requiring
process.
C) Potassium moves out of the tubules at a faster rate than it moves into the lumen of the tubules.
D) Sodium ions will follow potassium ions.
27) Studies of cricket Malpighian tubules revealed that potassium ions accumulated inside the
tubule, moving against the potassium concentration gradient. How would you expect the
movement of water to be influenced by the distribution of potassium ions?
A) Water would be forced out of the lumen of the Malpighian tubules through an osmotic
gradient.
B) The potassium gradient would have no effect on water movement.
C) There would be a net movement of water into the lumen of the tubules.
D) Water would be conserved, forming a hypertonic solution in the Malpighian tubules.
28) Why are the renal artery and vein critical to the process of osmoregulation in vertebrates?
A) The kidneys require constant and abnormally high oxygen supply to function.
B) The renal artery delivers blood with nitrogenous waste to the kidney and the renal vein brings
blood with less nitrogenous wastes away from the kidneys.
C) The kidneys require higher than normal levels of hormones.
D) The renal artery and vein are the main pathways regulating how much is produced by the
kidneys.
30) Materials are returned to the blood from the filtrate by which of the following processes?
A) filtration
B) reabsorption
C) secretion
D) excretion
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31) Excretory organs known as Malpighian tubules are present in ________.
A) flatworms
B) insects
C) jellyfish
D) sea stars
34) Choose a pair that correctly associates the mechanism for osmoregulation or nitrogen
removal with the appropriate animal.
A) protonephridium—earthworm
B) Malpighian tubule—frog
C) flame bulb—flat worm
D) exchange across the body surface—snake
35) An excretory system that is partly based on the filtration of fluid under high hydrostatic
pressure is the ________.
A) flame-bulb system of flatworms
B) protonephridia of rotifers
C) Malpighian tubules of insects
D) kidneys of vertebrates
36) The transfer of fluid from the glomerulus to Bowman's capsule ________.
A) results from active transport
B) transfers large molecules as easily as small ones
C) is very selective as to which sub-protein-sized molecules are transferred
D) is mainly a consequence of blood pressure in the capillaries of the glomerulus
37) Within a normally functioning kidney, red blood cells can be found in ________.
A) the vasa recta
B) Bowman's capsule
C) the proximal tubule
D) the collecting duct
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38) A primary reason that the kidneys have one of the highest metabolic rates of all body organs
is that ________.
A) they have membranes of varying permeability to water
B) they operate an extensive set of active-transport ion pumps
C) they are the body's only means of shedding excess nutrients
D) they have an abundance of myogenic smooth muscle
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In which of the labeled structures does passive water reabsorption take place?
A) only in B
B) only in B and D
C) in B, C, and E
D) Passive water reabsorption occurs throughout all of the nephron.
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42) Use the following figure to answer the question.
Selective secretion of toxins and drugs takes place in the structure labeled ________.
A) A
B) B
C) C
D) D
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43) Use the following figure to answer the question.
The structure labeled ________ can be influenced by hormones to change the concentration of
the urine.
A) B
B) C
C) D
D) E
44) The loop of Henle dips into the renal cortex. This is an important feature of osmoregulation
in terrestrial vertebrates because ________.
A) absorptive processes taking place in the loop of Henle are hormonally regulated
B) differential permeabilities of ascending and descending limbs of the loop of Henle are
important in establishing an osmotic gradient
C) the loop of Henle plays an important role in detoxification
D) additional filtration takes place along the loop of Henle
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45) Low selectivity of solute movement is a characteristic of ________.
A) H+ pumping to control pH
B) reabsorption mechanisms along the proximal tubule
C) filtration from the glomerular capillaries
D) secretion along the distal tubule
46) If ATP production in a human kidney was suddenly halted, urine production would
________.
A) decrease, and the urine would be hypoosmotic compared to plasma
B) increase, and the urine would be isoosmotic compared to plasma
C) increase, and the urine would be hyperosmotic compared to plasma
D) decrease, and the urine would be isoosmotic compared to plasma
47) Compared to wetland mammals, water conservation in mammals of arid regions is enhanced
by having more ________.
A) juxtamedullary nephrons
B) urinary bladders
C) ureters
D) podocytes
49) In humans, the transport epithelial cells in the ascending loop of Henle ________.
A) are the largest epithelial cells in the body
B) are not in contact with interstitial fluid
C) have plasma membranes of low permeability to water
D) are not affected by high levels of nitrogenous wastes
50) Which of the following contribute to maintaining the high osmolarity of the renal medulla?
I) active transport of salt from the upper region of the ascending limb
II) the spatial arrangement of juxtamedullary nephrons
III) diffusion of urea from the collecting duct
IV) diffusion of salt from the descending limb of the loop of Henle
A) All of these conditions contribute to the osmolarity of the medulla.
B) I, II, and III
C) I and IV
D) I, II, and IV
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51) Natural selection should favor the highest proportion of juxtamedullary nephrons in which of
the following species?
A) a river otter
B) a mouse species living in a tropical rain forest
C) a mouse species living in a temperate broadleaf forest
D) a mouse species living in a desert
52) If you are hiking through the desert for several days, one would pack which of the following
to ensure proper hydration?
A) a drink with a combination of water and electrolytes
B) caffeinated beverages
C) bottled water kept at room temperature
D) bottled water that had been frozen to ensure that it would be as cold as possible
54) After blood flow is artificially reduced at one kidney, you would expect that kidney to secrete
more of the hormone known as ________.
A) angiotensinogen
B) renin
C) antidiuretic hormone
D) atrial natriuretic peptide
55) After drinking alcoholic beverages, increased urine excretion is the result of ________.
A) increased aldosterone production
B) increased blood pressure
C) inhibited secretion of antidiuretic hormone (ADH)
D) increased reabsorption of water in the proximal tubule
56) Osmoregulatory adjustment via the atrial natriuretic peptide system can be triggered by
________.
A) sleeping for one hour
B) severe sweating on a hot day
C) eating a pizza with olives and pepperoni
D) drinking several glasses of water
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57) Antidiuretic hormone (ADH) and the renin-angiotensin-aldosterone system (RAAS) work
together in maintaining osmoregulatory homeostasis through which of the following ways?
A) ADH regulates the osmolarity of the blood by altering renal reabsorption of water, and the
RAAS maintains the osmolarity of the blood by stimulating both Na+ and water reabsorption.
B) ADH and the RAAS work antagonistically; ADH stimulates water reabsorption during
dehydration, and the RAAS causes increased excretion of water when it is in excess in body
fluids.
C) Both stimulate the adrenal gland to secrete aldosterone, which increases both blood volume
and pressure via its receptors in the urinary bladder.
D) ADH and the RAAS combine at the receptor sites of proximal tubule cells, where
reabsorption of essential nutrients takes place.
Answer: A
58) A human who has no access to fresh water but is forced to drink seawater instead will
________.
A) produce excessive antidiuretic hormone to remove more water but hold back salts
B) passively excrete excess water in order to remove the high concentration of ingested salt
C) release atrial natriuretic peptide to decrease blood pressure
D) risk becoming overhydrated within twelve hours
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3) Which of the following animals generally has the lowest volume of urine production?
A) vampire bat
B) salmon in fresh water
C) marine bony fish
D) freshwater flatworm
4) The high osmolarity of the renal medulla is maintained by all of the following except
A) active transport of salt from the upper region of the ascending limb.
B) the spatial arrangement of juxtamedullary nephrons.
C) diffusion of urea from the collecting duct.
D) diffusion of salt from the descending limb of the loop of Henle.
5) In which of the following species should natural selection favor the highest proportion of
juxtamedullary nephrons?
A) a river otter
B) a mouse species living in a temperate broadleaf forest
C) a mouse species living in a desert
D) a beaver
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6) African lungfish, which are often found in small stagnant pools of fresh water, produce urea as
a nitrogenous waste. What is the advantage of this adaptation?
A) Urea takes less energy to synthesize than ammonia.
B) Small stagnant pools do not provide enough water to dilute ammonia, which is toxic.
C) Urea forms an insoluble precipitate.
D) Urea makes lungfish tissue hypoosmotic to the pool.
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