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DATA FENY

No Kelompok Hewan V0 V1 V2 V3 V4
(mencit)
1 0,22 0,22 0,25 0,27 0,25
2 0,2 0,2 0,3 0,28 0,25
3 0,15 0,25 0,3 0,27 0,27
Kontrol
1 4 0,22 0,22 0,31 0,31 0,29
Negatif
5 0,22 0,25 0,29 0,27 0,27
𝑿 ± SEM 0,2020 ± 0,2280 ± 0,2900 ± 0,2800 ± 0,2660 ±
0,01356 0,00970 0,01049 0,00775 0,00748
1 0,15 0,15 0,25 0,2 0,18
2 0,15 0,18 0,18 0,18 0,18
3 0,2 0,22 0,22 0,25 0,2
Kontrol
2 4 0,15 0,2 0,2 0,22 0,22
Positif
5 0,22 0,27 0,27 0,25 0,25
𝑿 ± SEM 0,1740 ± 0,2040 ± 0,2240 ± 0,2200 ± 0,2060 ±
0,01503 0,02015 0,01631 0,01378 0,01327
1 0,22 0,18 0,15 0,18 0,18
2 0,22 0,25 0,2 0,22 0,2
P1 (ekstrak 3 0,2 0,18 0,22 0,27 0,27
3 250mg/kgB 4 0,27 0,22 0,22 0,18 0,18
B) 5 0,25 0,22 0,22 0,22 0,2
𝑿 ± SEM 0,2320 ± 0,2100 ± 0,2020 ± 0,2140 ± 0,2060 ±
0,01241 0,01342 0,01356 0,01661 0,01661
1 0,2 0,2 0,27 0,25 0,2
2 0,25 0,18 0,22 0,2 0,22
P2 (ekstrak 3 0,22 0,18 0,2 0,18 0,18
4 500mg/kgB 4 0,25 0,22 0,22 0,25 0,22
B) 5 0,2 0,22 0,18 0,18 0,2
𝑿 ± SEM 0,2240 ± 0,2000 ± 0,2180 ± 0,2120 ± 0,2040 ±
0,01122 0,00894 0,01497 0,01594 0,00748

A. Descriptives

Kelompok Statistic Std. Error


V0 Kontrol Negatif Mean ,2020 ,01356
95% Confidence Interval for Lower Bound ,1643
Mean Upper Bound ,2397
5% Trimmed Mean ,2039
Median ,2200
Variance ,001
Std. Deviation ,03033
Minimum ,15
Maximum ,22
Range ,07
Interquartile Range ,05
Skewness -1,838 ,913
Kurtosis 3,263 2,000
Kontrol Positif Mean ,1740 ,01503
95% Confidence Interval for Lower Bound ,1323
Mean Upper Bound ,2157
5% Trimmed Mean ,1728
Median ,1500
Variance ,001
Std. Deviation ,03362
Minimum ,15
Maximum ,22
Range ,07
Interquartile Range ,06
Skewness ,806 ,913
Kurtosis -2,195 2,000
P1 Mean ,2320 ,01241
95% Confidence Interval for Lower Bound ,1975
Mean Upper Bound ,2665
5% Trimmed Mean ,2317
Median ,2200
Variance ,001
Std. Deviation ,02775
Minimum ,20
Maximum ,27
Range ,07
Interquartile Range ,05
Skewness ,477 ,913
Kurtosis -1,084 2,000
P2 Mean ,2240 ,01122
95% Confidence Interval for Lower Bound ,1928
Mean Upper Bound ,2552
5% Trimmed Mean ,2239
Median ,2200
Variance ,001
Std. Deviation ,02510
Minimum ,20
Maximum ,25
Range ,05
Interquartile Range ,05
Skewness ,196 ,913
Kurtosis -3,031 2,000
V1 Kontrol Negatif Mean ,2280 ,00970
95% Confidence Interval for Lower Bound ,2011
Mean Upper Bound ,2549
5% Trimmed Mean ,2283
Median ,2200
Variance ,000
Std. Deviation ,02168
Minimum ,20
Maximum ,25
Range ,05
Interquartile Range ,04
Skewness -,069 ,913
Kurtosis -1,824 2,000
Kontrol Positif Mean ,2040 ,02015
95% Confidence Interval for Lower Bound ,1481
Mean Upper Bound ,2599
5% Trimmed Mean ,2033
Median ,2000
Variance ,002
Std. Deviation ,04506
Minimum ,15
Maximum ,27
Range ,12
Interquartile Range ,08
Skewness ,548 ,913
Kurtosis ,455 2,000
P1 Mean ,2100 ,01342
95% Confidence Interval for Lower Bound ,1728
Mean Upper Bound ,2472
5% Trimmed Mean ,2094
Median ,2200
Variance ,001
Std. Deviation ,03000
Minimum ,18
Maximum ,25
Range ,07
Interquartile Range ,06
Skewness ,185 ,913
Kurtosis -1,519 2,000
P2 Mean ,2000 ,00894
95% Confidence Interval for Lower Bound ,1752
Mean Upper Bound ,2248
5% Trimmed Mean ,2000
Median ,2000
Variance ,000
Std. Deviation ,02000
Minimum ,18
Maximum ,22
Range ,04
Interquartile Range ,04
Skewness ,000 ,913
Kurtosis -3,000 2,000
V2 Kontrol Negatif Mean ,2900 ,01049
95% Confidence Interval for Lower Bound ,2609
Mean Upper Bound ,3191
5% Trimmed Mean ,2911
Median ,3000
Variance ,001
Std. Deviation ,02345
Minimum ,25
Maximum ,31
Range ,06
Interquartile Range ,04
Skewness -1,744 ,913
Kurtosis 3,322 2,000
Kontrol Positif Mean ,2240 ,01631
95% Confidence Interval for Lower Bound ,1787
Mean Upper Bound ,2693
5% Trimmed Mean ,2239
Median ,2200
Variance ,001
Std. Deviation ,03647
Minimum ,18
Maximum ,27
Range ,09
Interquartile Range ,07
Skewness ,136 ,913
Kurtosis -1,630 2,000
P1 Mean ,2020 ,01356
95% Confidence Interval for Lower Bound ,1643
Mean Upper Bound ,2397
5% Trimmed Mean ,2039
Median ,2200
Variance ,001
Std. Deviation ,03033
Minimum ,15
Maximum ,22
Range ,07
Interquartile Range ,05
Skewness -1,838 ,913
Kurtosis 3,263 2,000
P2 Mean ,2180 ,01497
95% Confidence Interval for Lower Bound ,1764
Mean Upper Bound ,2596
5% Trimmed Mean ,2172
Median ,2200
Variance ,001
Std. Deviation ,03347
Minimum ,18
Maximum ,27
Range ,09
Interquartile Range ,06
Skewness ,888 ,913
Kurtosis 1,468 2,000
V3 Kontrol Negatif Mean ,2800 ,00775
95% Confidence Interval for Lower Bound ,2585
Mean Upper Bound ,3015
5% Trimmed Mean ,2789
Median ,2700
Variance ,000
Std. Deviation ,01732
Minimum ,27
Maximum ,31
Range ,04
Interquartile Range ,03
Skewness 1,925 ,913
Kurtosis 3,667 2,000
Kontrol Positif Mean ,2200 ,01378
95% Confidence Interval for Lower Bound ,1817
Mean Upper Bound ,2583
5% Trimmed Mean ,2206
Median ,2200
Variance ,001
Std. Deviation ,03082
Minimum ,18
Maximum ,25
Range ,07
Interquartile Range ,06
Skewness -,256 ,913
Kurtosis -1,989 2,000
P1 Mean ,2140 ,01661
95% Confidence Interval for Lower Bound ,1679
Mean Upper Bound ,2601
5% Trimmed Mean ,2128
Median ,2200
Variance ,001
Std. Deviation ,03715
Minimum ,18
Maximum ,27
Range ,09
Interquartile Range ,07
Skewness ,792 ,913
Kurtosis ,211 2,000
P2 Mean ,2120 ,01594
95% Confidence Interval for Lower Bound ,1678
Mean Upper Bound ,2562
5% Trimmed Mean ,2117
Median ,2000
Variance ,001
Std. Deviation ,03564
Minimum ,18
Maximum ,25
Range ,07
Interquartile Range ,07
Skewness ,391 ,913
Kurtosis -3,127 2,000
V4 Kontrol Negatif Mean ,2660 ,00748
95% Confidence Interval for Lower Bound ,2452
Mean Upper Bound ,2868
5% Trimmed Mean ,2656
Median ,2700
Variance ,000
Std. Deviation ,01673
Minimum ,25
Maximum ,29
Range ,04
Interquartile Range ,03
Skewness ,512 ,913
Kurtosis -,612 2,000
Kontrol Positif Mean ,2060 ,01327
95% Confidence Interval for Lower Bound ,1692
Mean Upper Bound ,2428
5% Trimmed Mean ,2050
Median ,2000
Variance ,001
Std. Deviation ,02966
Minimum ,18
Maximum ,25
Range ,07
Interquartile Range ,06
Skewness ,839 ,913
Kurtosis -,411 2,000
P1 Mean ,2060 ,01661
95% Confidence Interval for Lower Bound ,1599
Mean Upper Bound ,2521
5% Trimmed Mean ,2039
Median ,2000
Variance ,001
Std. Deviation ,03715
Minimum ,18
Maximum ,27
Range ,09
Interquartile Range ,06
Skewness 1,841 ,913
Kurtosis 3,614 2,000
P2 Mean ,2040 ,00748
95% Confidence Interval for Lower Bound ,1832
Mean Upper Bound ,2248
5% Trimmed Mean ,2044
Median ,2000
Variance ,000
Std. Deviation ,01673
Minimum ,18
Maximum ,22
Range ,04
Interquartile Range ,03
Skewness -,512 ,913
Kurtosis -,612 2,000

B. Tests of Normality

Kolmogorov-Smirnova Shapiro-Wilk
Kelompok Statistic df Sig. Statistic df Sig.
V0 Kontrol Negatif ,324 5 ,095 ,717 5 ,014
Kontrol Positif ,362 5 ,031 ,760 5 ,036
P1 ,267 5 ,200* ,939 5 ,656
P2 ,250 5 ,200* ,814 5 ,105
V1 Kontrol Negatif ,245 5 ,200* ,871 5 ,272
Kontrol Positif ,161 5 ,200* ,985 5 ,957
P1 ,241 5 ,200* ,877 5 ,295
P2 ,241 5 ,200* ,821 5 ,119
V2 Kontrol Negatif ,300 5 ,161 ,813 5 ,103
Kontrol Positif ,162 5 ,200* ,971 5 ,884
P1 ,324 5 ,095 ,717 5 ,014
P2 ,276 5 ,200* ,933 5 ,616
V3 Kontrol Negatif ,318 5 ,109 ,701 5 ,010
Kontrol Positif ,235 5 ,200* ,903 5 ,429
P1 ,236 5 ,200* ,874 5 ,284
P2 ,257 5 ,200* ,792 5 ,069
V4 Kontrol Negatif ,231 5 ,200* ,881 5 ,314
Kontrol Positif ,210 5 ,200* ,897 5 ,391
P1 ,364 5 ,029 ,757 5 ,035
P2 ,231 5 ,200* ,881 5 ,314
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction

C. Kruskal Wallis Test

Ranks
Kelompok N Mean Rank
V0 Kontrol Negatif 5 9,70
Kontrol Positif 5 5,50
P1 5 14,20
P2 5 12,60
Total 20
V1 Kontrol Negatif 5 14,00
Kontrol Positif 5 9,20
P1 5 10,40
P2 5 8,40
Total 20
V2 Kontrol Negatif 5 17,50
Kontrol Positif 5 9,20
P1 5 6,90
P2 5 8,40
Total 20
V3 Kontrol Negatif 5 17,70
Kontrol Positif 5 8,70
P1 5 8,10
P2 5 7,50
Total 20
V4 Kontrol Negatif 5 17,20
Kontrol Positif 5 8,20
P1 5 8,00
P2 5 8,60
Total 20

Test Statisticsa,b
V0 V1 V2 V3 V4
Chi-Square 6,702 2,800 10,048 10,327 8,926
df 3 3 3 3 3
Asymp. Sig. ,082 ,424 ,018 ,016 ,030
a. Kruskal Wallis Test
b. Grouping Variable: Kelompok

D. Post Hoc Mann Whitney Test


a). Kontrol Negatif dengan Kontrol Positif

Ranks
Kelompok N Mean Rank Sum of Ranks
V2 Kontrol Negatif 5 7,70 38,50
Kontrol Positif 5 3,30 16,50
Total 10
V3 Kontrol Negatif 5 8,00 40,00
Kontrol Positif 5 3,00 15,00
Total 10
V4 Kontrol Negatif 5 7,80 39,00
Kontrol Positif 5 3,20 16,00
Total 10

Test Statisticsa
V2 V3 V4
Mann-Whitney U 1,500 ,000 1,000
Wilcoxon W 16,500 15,000 16,000
Z -2,312 -2,652 -2,447
Asymp. Sig. (2-tailed) ,021 ,008 ,014
Exact Sig. [2*(1-tailed Sig.)] ,016b ,008b ,016b

Nilai sig p<0.05 berarti ada perbedaan bermakna antara kelompok kontrol negatif dengan
kelompok kontrol positif pada jam ke 2, 3 dan 4

b). Kontrol negatif dengan P1


Ranks
Kelompok N Mean Rank Sum of Ranks
V2 Kontrol Negatif 5 8,00 40,00
P1 5 3,00 15,00
Total 10
V3 Kontrol Negatif 5 7,70 38,50
P1 5 3,30 16,50
Total 10
V4 Kontrol Negatif 5 7,40 37,00
P1 5 3,60 18,00
Total 10

Test Statisticsa
V2 V3 V4
Mann-Whitney U ,000 1,500 3,000
Wilcoxon W 15,000 16,500 18,000
Z -2,652 -2,386 -2,028
Asymp. Sig. (2-tailed) ,008 ,017 ,043
Exact Sig. [2*(1-tailed Sig.)] ,008b ,016b ,056b

Nilai signifikansi p<0.05 berarti ada perbedaan bermakna antara kelompok kontrol negatif
dengan kelompok P1 (kelompok yang diberi ekstrak 250 mg/kgBB) pada jam ke 2,3 dan 4
c). Kontrol negatif dengan P2

Ranks
Kelompok N Mean Rank Sum of Ranks
V2 Kontrol Negatif 5 7,80 39,00
P2 5 3,20 16,00
Total 10
V3 Kontrol Negatif 5 8,00 40,00
P2 5 3,00 15,00
Total 10
V4 Kontrol Negatif 5 8,00 40,00
P2 5 3,00 15,00
Total 10

Test Statisticsa
V2 V3 V4
Mann-Whitney U 1,000 ,000 ,000
Wilcoxon W 16,000 15,000 15,000
Z -2,417 -2,660 -2,643
Asymp. Sig. (2-tailed) ,016 ,008 ,008
Exact Sig. [2*(1-tailed Sig.)] ,016b ,008b ,008b

Nilai signifikansi p<0.05 berarti ada perbedaan bermakna antara kelompok kontrol negatif
dengan kelompok P2 (kelompok yang diberi ekstrak 500 mg/kgBB) pada jam ke 2,3 dan 4

d). Kontrol Positif dengan P1

Ranks
Kelompok N Mean Rank Sum of Ranks
V2 Kontrol Positif 5 6,20 31,00
P1 5 4,80 24,00
Total 10
V3 Kontrol Positif 5 5,80 29,00
P1 5 5,20 26,00
Total 10
V4 Kontrol Positif 5 5,60 28,00
P1 5 5,40 27,00
Total 10
Test Statisticsa
V2 V3 V4
Mann-Whitney U 9,000 11,000 12,000
Wilcoxon W 24,000 26,000 27,000
Z -,757 -,322 -,109
Asymp. Sig. (2-tailed) ,449 ,747 ,913
Exact Sig. [2*(1-tailed Sig.)] ,548b ,841b 1,000b

Nilai signifikansi p>0.05 berarti tidak ada perbedaan bermakna antara kelompok kontrol
positif dengan kelompok P1 (kelompok yang diberi ekstrak 250 mg/kgBB) pada jam ke 2,3
dan 4

e). Kontrol positif dengan P2

Ranks
Kelompok N Mean Rank Sum of Ranks
V2 Kontrol Positif 5 5,70 28,50
P2 5 5,30 26,50
Total 10
V3 Kontrol Positif 5 5,90 29,50
P2 5 5,10 25,50
Total 10
V4 Kontrol Positif 5 5,40 27,00
P2 5 5,60 28,00
Total 10

Test Statisticsa
V2 V3 V4
Mann-Whitney U 11,500 10,500 12,000
Wilcoxon W 26,500 25,500 27,000
Z -,213 -,438 -,108
Asymp. Sig. (2-tailed) ,831 ,661 ,914
Exact Sig. [2*(1-tailed Sig.)] ,841b ,690b 1,000b

Nilai signifikansi p>0.05 berarti tidak ada perbedaan bermakna antara kelompok kontrol
negatif dengan kelompok P2 (kelompok yang diberi ekstrak 500 mg/kgBB) pada jam ke 2,3
dan 4
f). P1 dengan P2

Ranks
Kelompok N Mean Rank Sum of Ranks
V2 P1 5 5,10 25,50
P2 5 5,90 29,50
Total 10
V3 P1 5 5,60 28,00
P2 5 5,40 27,00
Total 10
V4 P1 5 5,00 25,00
P2 5 6,00 30,00
Total 10
Test Statisticsa
V2 V3 V4
Mann-Whitney U 10,500 12,000 10,000
Wilcoxon W 25,500 27,000 25,000
Z -,447 -,108 -,548
Asymp. Sig. (2-tailed) ,655 ,914 ,584
Exact Sig. [2*(1-tailed Sig.)] ,690b 1,000b ,690b

Nilai signifikansi p>0.05 berarti tidak ada perbedaan bermakna antara kelompok P1
(kelompok yang diberi ekstrak 250mg/kgBB) dengan kelompok P2 (kelompok yang diberi
ekstrak 500 mg/kgBB) pada jam ke 2,3 dan 4