Generic name: Isoxsuprine

Brand Name: Duvadilan

Classification: β2 adrenoreceptor agonist

Indication
 Peripheral and cerebral vascular insufficiency with spastic component
showing symptoms:

 Dizziness

 Forgetfulness

 Confusion

 Visual, auditory and speech abnormalities

 Coldness and numbness of limbs

 Color changes and ischemic ulcers

 Raynaud disease

 Uterine hypermotility disorders:

 Threatened abortion

 Premature labor

 Dysmenorrhea

Contraindications:
 recent arterial hemorrhage heart disease, severe anemia
 should not be administered immediately post partum and premature labor.
 avoid parenteral administration to patients with hypotension, tachycardia,
premature detachment of placenta or immediate postpartum.
Drug Action
-Chemically similar to sympathomimetic amines and often described as beta
adrenergic agonist. However, the drug appear to be a musculotropic vasodilator
rand its effects are not blocked by propanolol.

Adverse and Side Effects

 Transient flushing
 Hypotension
 Rashes
 Gastrointestinal (GI)disturbances
 Maternal pulmonary edema
 Fetal tachycardia
 Transient palpitations
 Dizziness

Nursing Responsibilities
 Assess patient’s condition before therapy. Assess potential benefits from
drug therapy.
 Monitor for possible drug induced adverse reactions:
 Hypotension
 Tachycardia
 Nausea
 Vomiting
 Dizziness
 Severe rash
 Inform the patient about possible side effects, adverse symptoms to report.