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Formulary
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DEPARTMENT OF HEALTH
MESSAGE
The revitalization of the Fourmula One Plus for Health as the framework of the
healthcare reform agenda of the national government is anchored on the values
of equitable and inclusive health system, transparent and accountable provision
of quality health services, and efficient use of resources. The 8th edition of the
Philippine National Formulary (PNF) Essential Medicines List (EML) is a tool to
exercise these values while contributing to the achievement of the objectives of
financial protection and better health outcomes.
As an essential medicines list, its previous editions have been the basis of tailored
procurement of medicines in public health facilities while providing efficient use
of limited resources. It is also the basis of the Philippine Health Insurance
Corporation (PhilHealth) in reimbursing claims to end-users for medicines use.
With its new format and content, the PNF EML 8th edition can now maximize the
PNF’s contribution to the rational use of medicines. Its abridged content is
intended to provide concise evidence-based drug information which is vital in
medical practice.
The latest PNF EML is a useful tool to ensure rational prescribing, dispensing and
administration of medicines. I would like to encourage our health professionals to
fully utilize it in their medicines procurement as well as in their day-to-day clinical
decision-making.
Let us continue to work for our shared vision of all for health towards health for
all!
Mabuhay!
21 luly 2016
DEPARTMENT MEMORANDUM
No.2016- 0298
____________________________________________________________________________________________
On the other hand, for the bidding of the following solid oral dosage forms,
the specific type of tablet should be clearly reflected in the purchase request:
1. film-coated tablets:
2. soluble tablets;
3. dispersible tablets;
4. effervescent tablets;
5. chewable tablets:
6. tablets for use in the mouth (including orally disintegrating, sublingual
and buccal tablets): and
7. modified-release tablets (including delayed-release tablets
gastro-resistant/enteric-coated tablets) and sustained-release tablets
(extended-/prolonged-release tablets)).
pen. G - Penicillin G
Soln. - Solution
MEASUREMENTS:
1 grain = 60 mg
½ grain = 30 mg
Quantities of 1 gram or more should be written as 1 g, etc.
Quantities of less than 1 gram should be written in milligrams, e.g., 500 mg,
not 0.5 g.
When decimals are unavoidable, a zero should be written before the decimal
point where there is no figure, e.g., 0.5 mL, not .5 mL.
The term milliliter (mL) should be used and not cubic centimeters or cc or
m3.
1
Composition:
Na+ — 130 mmol/L
K+ — 4 mmol/L
Ca++ — 3 mmol/L
Cl‐ — 109 mmol/L
Acetate — 28 mmol/L
Acetazolamide (B) Oral: 250 mg tablet
Acetylcysteine Oral: 600 mg effervescent tablet
100 mg and 200 mg sachet
100 mg/5 mL granules for suspension, 150 mL
Inj.: 200 mg/mL, 10 mL ampul (IV infusion) (1, 2)
200 mg/mL, 25 mL bottle (IV infusion)
Inhalation:
100 mg/mL, 3 mL ampule solution for inhalation
Aciclovir Oral: 200 mg, 400 mg and 800 mg tablet
200 mg/5 mL suspension, 60 mL and 120 mL
Inj.: 25 mg/mL, 10 mL vial (IV infusion)
Eye Ointment: 3%, 4.5 g tube
Activated Charcoal Oral: powder, USP grade given as slurry
B
Bacitracin + Neomycin + Ointment:
Polymixin B 200 units bacitracin + 3 mg neomycin (as sulfate)
+ 4000 units polymyxin B (as sulfate)/g, 10 g
tube
Baclofen Oral: 10 mg tablet
Balanced Multiple Maintenance Inj.: with 5% dextrose, 250 mL and 500 mL (infants)
Solution and 1 L (children and adults) bottle/bag (IV
infusion)
5
C
Calamine, Plain Lotion: 8%, 60 mL and 120 mL bottle
Calcipotriol Ointment: 50 microgram/g, 30 g tube or bottle
Calcipotriol + Betamethasone Ointment: 50 microgram calcipotriol (as hydrate ) + 500
microgram betamethasone (as dipropionate)/g,
30 g tube
Calcitriol (1, 2) Oral: 0.25 microgram capsule
Calcium Oral: tablet (equiv. to 500 mg elemental calcium) (as
lactate)
tablet/chewable tablet (equiv. to 500 mg and 600
mg elemental calcium) (as carbonate)
powder, USP grade (as chloride)
Inj.: 10% solution in 10 mL ampul (IV) (as gluconate)
Calcium Carbonate Oral: tablet/chewable tablet (equiv. to 500 mg and 600
mg elemental calcium)
Calcium Carbonate + Oral: Equiv. to 500 mg elemental Ca + 400 IU Vit. D3
Cholecalciferol (vitamin D3) Equiv. to 600 mg elemental Ca + 400 IU Vit. D3
Calcium Folinate (leucovorin Inj.: 10 mg/mL, 5 mL ampul/vial (IM, IV)
calcium) (1, 2) 50 mg vial (IM, IV)
Calcium Gluconate (1, 2) Inj.: 10%, 10 mL ampul/vial (IV)
10%, 20 mL and 25 mL bottle (IV)
Calcium Sennosides (equivalent Oral: 8.77 mg and 17.54 mg (calculated as sennoside B)
to Standardized Senna tablet
concentrate)
Capecitabine (1, 2) Oral: 150 mg and 500 mg tablet
Capreomycin Inj: 1 gram powder for injection (IV, IM)
Captopril Oral: 25 mg and 50 mg tablet
Carbachol Intraocular Solution: 0.01%, 1.5 mL vial
8
Cyclophosphamide (1, 2) Inj.: powder, 200 mg, 500 mg and 1 g vial (IV)
Cycloserine Oral: 250 mg capsule
Cyproterone (as acetate) (1, 2) Oral: 50 mg tablet
Cytarabine (1, 2) Inj.: 20 mg/mL, 5 mL ampul (IM, SC, intrathecal)
100 mg/mL solution for injection, 1 mL, 5mL and
10 mL
D
Dacarbazine (1, 2) Inj.: powder, 100 mg and 200 mg vial (IV, IV infusion)
Daclatasvir Oral: 60 mg tablet
Dactinomycin (1, 2) Inj.: powder, 500 micrograms vial (IV)
Danazol (1) Oral: 200 mg capsule
Dantrolene (as sodium salt) Oral: 25 mg and 50 mg capsule (1)
Inj.: 20 mg (with mannitol 3 g)/vial (for reconstitution
with 60 mL sterile water for injection) (IV) (1, 2)
Composition:
Dextrose — 50 g/L
Na+ — 130 mmol/L
K+ — 4 mmol/L
Ca++ — 1.22 – 1.5 mmol/L
Cl‐ — 109 mmol/L
Lactate — 28 mmol/L
5% Dextrose in Water Inj.: 250 mL, 500 mL and 1 L bottle/bag (IV infusion
and as vehicle for IV medications)
10% Dextrose in Water Inj.: 250 mL, 500 mL and 1 L bottle/bag (IV infusion)
13
F
Factor IX Complex Concentrate Inj.: 100 IU/mL, 5 mL and 10 mL vial (IV)
(coagulation factors II, VII, IX, X) lyophilized powder, 500 IU vial + diluent (IV)
(1, 2)
Factor VIII Concentrate (1, 2) Inj.: lyophilized powder, 100 IU/g vial + diluent (IV)
Famotidine Oral: 20 mg tablet
18
G
Gabapentin Oral: 100 mg and 300 mg capsule
Gadobutrol Inj.: 1.0 mmol/mL solution for injection, 15 mL vial
1.0 mmol/mL solution for injection, 5 mL pre-filled
syringe
Ganciclovir Eye Gel: 0.15%, 5 g tube
Inj.: 500 mg vial (IV infusion) (as sodium) (1, 2)
Gas Forming Agent Oral: Components per tablet:
H
Haloperidol (1) Oral: 2 mg, 5 mg, and 10 mg tablet (B)
Inj.: 5 mg/mL, 1 mL ampul (IM)
50 mg/mL, 1 mL (oily) ampul (IM) (as decanoate)
Halothane (1) Inhalation: 250 mL bottle
21
Composition:
Concentrates (g/L)
Glucose – 0 – 49.5 g
Sodium chloride – 216.19 g – 270.8 g
Potassium chloride – 5.25 g – 6.7 g
Calcium chloride – 6.47 g – 9.9 g
Magnesium chloride – 3.58 g – 4.75 g
Glacial Acetic Acid – 8.1 g – 8.46 g
Purified Water - 1000 mL
I
Ibuprofen Oral: 200 mg and 400 mg tablet
100 mg/5 mL, 60 mL syrup/suspension
200 mg/5 mL, 60 mL suspension
Idarubicin (as hydrochloride) Inj.: powder, 5 mg vial (IV)
(1, 2)
Ifosfamide (1, 2) Inj.: powder, 1 g and 2 g vial (IV infusion)
Imatinib (as mesilate) (1, 2) Inj.: 100 mg and 400 mg tablet
Imiglucerase Inj: 400 U powder for intravenous infusion, 20 mL vial
Imiquimod Cream: 5%, aluminum foil sachet
23
K
Kanamycin (as sulfate) Inj.: 1 g vial (IM)
Ketamine (as hydrochloride) Inj.: ⊗50 mg/mL, 10 mL vial (IM, IV)
(1, A1)
Ketoconazole Cream: 2% (20 mg/ g), 3.5 g and 15 g aluminum collapsible
tube
Shampoo: 2% (20 mg/ g), 6 mL foil sachet, 10 mL, 60 mL
and 100 mL bottle
Ketoprofen Oral: 100 mg tablet
Inj.: 50 mg/mL, 2 mL ampul (IM)
Ketorolac (as tromethamol) Inj.: 30 mg/mL, 1 mL ampul (IM, IV)
L
Lactated Ringer's Solution Inj.: 500 mL and 1 L bottle/bag (IV infusion)
(Ringer's Lactate) Composition:
26
M
Magnesium Sulfate (as Inj.: 250 mg/mL, 2 mL and 10 mL ampul (IM, IV)
heptahydrate) (1, 2) 250 mg/mL, 10 mL, 20 mL and 50 mL vial (IV)
500 mg/mL, 2 mL and 10 mL ampul (IM, IV)
Mannitol Inj.: 20%, 250 mL and 500 mL bottle (IV)
Mebendazole Oral: 100 mg tablet/capsule
500 mg tablet/chewable tablet
50 mg/mL suspension, 10 mL
100 mg/5 mL suspension, 30 mL and 60 mL
28
Composition:
Infants (per 1 mL Children (per 5 mL
drops) syrup
Vitamin A 325 – 380 mcg 350 – 400 mcg
Vitamin B1 0.2 – 0.4 mg 0.5 – 1.0 mg
Vitamin B2 0.3 – 0.4 mg 0.7 – 0.9 mg
Vitamin B6 0.3 – 0.6 mg 0.9 – 1.6 mg
Vitamin B12 0.3 – 0.4 mcg 0.9 – 3.0 mcg
Vitamin C 30 mg 35 – 55 mg
Vitamin D 200 IU (5 mcg) 200 IU (5 mcg)
Vitamin E 3 – 4 mg 5 – 7 mg
Folic Acid 20 – 65 mcg 40 – 300 mcg
Niacin 1 – 5 mg 5 – 18 mg
Adult (per
tablet/capsule)
Vitamin A 600 – 700 mcg or
2,000 – 2,500 IU
Vitamin B1 1.3 – 1.7 mg
Vitamin B2 0.7 – 1.3 mg
Vitamin B6 1.6 – 2 mg
Vitamin B12 2 – 6 mcg
Vitamin C 65 - 80 mg
Vitamin D 400 IU (10 mcg)
Vitamin E 6 – 10 mg (15 –
30 IU)
Folic Acid 400 mcg
Niacin 13 – 23 mg
N
N-acetyl Penicillamine (1, 2) Oral: crystals, 25 g/bottle
Nalbuphine (as hydrochloride) Inj.: 10 mg/mL, 1 mL ampul (IM, IV, SC)
(A1)
Nalidixic Acid Oral: 500 mg tablet
32
O
Octreotide (as acetate) (1, 2) Inj.: 100 micrograms/mL and 500 micrograms/mL, 1
mL ampul (IV infusion)
Ofloxacin Oral: 200 mg tablet
33
Sodium — 75
Chloride — 65
Potassium — 20
Citrate — 10
Glucose anhydrous — 75
Total osmolarity — 245
P
Paclitaxel (1, 2) Inj.: 6 mg/mL, 5 mL, 17 mL, 25 mL and 43.4 mL vial
(IV, IV infusion)
Paliperidone Inj: 50 mg/0.5 mL, 75 mg/0.75 mL, 100 mg/mL and
150 mg/1.5 mL prolonged release suspension
for injection (IM)
Pancuronium (as bromide) (1) Inj.: 2 mg/mL, 2 mL ampul (IM, IV)
Para-aminosalicylic acid Sachet:
4 gram enteric coated delayed release granules in
sachet
Paracetamol Oral: 300 mg and 500 mg tablet
100 mg/mL drops, 15 mL (alcohol‐free)
120 mg/5 mL (125 mg/5 mL) syrup/suspension, 30
mL, 60 mL and 120 mL (alcohol‐free)
250 mg/5 mL syrup/suspension, 30 mL, 60 mL
and 120 mL (alcohol‐free)
Inj: 150 mg/mL, 2mL ampule solution for injection
(IM/IV)
10 mg/mL, 50 mL and 100 mL vial solution for
infusion (IV)
Rectal: 125 mg and 250 mg suppository
Peginterferon Alfa 2A (1, 2) Inj.: 135 micrograms/0.5 mL pre‐filled syringe (SC)
Penicillin G Benzathine Inj.: 1,200,000 units vial (MR) (IM)
(benzathine benzylpenicillin)
Penicillin G Crystalline Inj.: 1,000,000 units vial (IM, IV)
(benyzylpenicillin) (as sodium 5,000,000 units vial (IM, IV)
salt) (1, 2)
Peritoneal Dialysis Solution Solution:
Sterile with 1.5%, 2.3 % and 4.25% dextrose, 2 L
and 5 L bottle
35
Q
Quetiapine (as fumarate) Oral: 25 mg, 100 mg, 200 mg and 300 mg tablet
R
Rabeprazole sodium Oral: 10 mg and 20 mg tablets
Rabies Immunoglobulin Inj.: 150 IU/mL, 2 mL and 5 mL vial (IM)
(human) 150 IU/mL, 2mL, 5 mL and 10 mL ampul (IM)
Rabies vaccine, Chick Embryo Inj.: lyophilized powder, 2.5 IU/mL, 1 dose vial + 1 mL
Cell (purified, inactivated) diluent (ID, IM)
Rabies vaccine, Vero Cell Inj.: lyophilized powder, 2.5 IU/ 0.5 mL, vial + diluent (ID,
(purified) IM)
2.5 IU/mL suspension, 1 mL vial (IM)
Ranitidine (as hydrochloride) Oral: 150 mg and 300 mg tablet
75 mg/5 mL syrup, 60 mL and 150 mL
Inj.: 25 mg/mL, 2 mL ampul/vial (IM, IV, IV infusion)
Regular, Insulin (recombinant Inj.: 100 IU/mL, 3 mL pre‐filled syringe (SC, IV/IM)
DNA human) 100 IU/mL, 5 mL and 10 mL vial (SC, IV/IM)
38
S
Sacubitril/Valsartan Oral: 50 mg, 100 mg and 200 mg tablet (Restricted for
patients with symptomatic heart failure with
reduced injection fraction (HF-rEF) and for those
who have been on stable doses of angiotensin-
converting enzyme (ACE) inhibitors and/or
angiotensin receptor blockers (ARBs) but remain
symptomatic.)
Salbutamol (as sulfate) Oral: 2 mg/5 mL syrup, 60 mL
Inhalation:
Dry Powder Inhaler (DPI):
200 micrograms/dose with appropriate
accompanying dispenser
Metered Dose Inhaler (MDI):
39
Composition:
Na+ — 154 mmol/L
Cl‐ — 154 mmol/L
Sodium Dichloroisocyanurate Solution: 3.5 mg tablet (2 mg free available chlorine)
(to be used for water 8.68 mg tablet (5 mg free available chlorine)
purification) 12.5 mg tablet (8 mg free available chlorine)
17 mg tablet (10 mg free available chlorine)
67 mg tablet (40 mg free available chlorine)
Sodium Hyaluronate Ophthalmic Solution: 0.1% (1 mg/mL), 5 mL bottle
Sodium Hypochlorite Solution: 1.25% available chlorine for water purification
Sodium Iodide 1311 (1, 2) Oral: capsule with radioactivity range of 0.8 to 100 mCi
per capsule
capsule with radioactivity range of 1.0 to 250 mCi
per capsule
40
V
Valaciclovir (as hydrochloride) Oral: 500 mg tablet
Valganciclovir Oral: 450 mg tablet
Valproic Acid Oral: 250 mg/5 mL syrup, 120 mL
Inj: 500 mg/ 5mL IV infusion, 5 mL vial
Valsartan Oral: 80 mg and 160 mg tablet/film coated tablet
Valsartan + Hydrochlorothiazide Oral: 80 mg valsartan + 12.5 mg hydrochlorothiazide
tablet
Vancomycin (as hydrochloride) Inj.: 500 mg and 1 g vial (IV)
*Restricted Antimicrobial
Varenicline Oral: 0.5 mg and 1 mg tablet
Varicella Zoster Immunoglobulin Inj.: 125 units/1.25 mL vial (IM)
(VZIG)
Vecuronium (as bromide) (1) Inj.: freeze‐dried powder, 4 mg/mL ampul + 1 mL solvent
(IV)
Verapamil (as hydrochloride) Oral: 80 mg tablet (B)
240 mg MR tablet (for maintenance therapy)
Inj.: 2.5 mg/mL, 2 mL ampul (IV) (1, 2)
Vinblastine (as sulfate) (1, 2) Inj.: powder, 10 mg vial for reconstitution (IV)
1 mg/mL, 10 mL vial (IV)
Vincristine (as sulfate) (1, 2) Inj.: 1 mg/mL, 1 mL and 2 mL vial (IV)
Vitamin A (see Retinol)
Vitamin B1 B6 B12 Oral: 100 mg B1 + 5 mg B6 + 50 microgram B12 per
tablet/capsule
10 mg B1 + 5 mg B6 + 5 micrograms B12 per 0.6
mL drops, 15 mL
Inj.: 100 mg B1 + 100 mg B6 + 1 mg B12 per 3 mL
ampul (IV)
100 mg B1 + 100 mg B6 + 1 mg B12 per mL, 10 mL
vial (IV)
Vitamin B6 (see Pyridoxine)
Vitamin C (see Ascorbic Acid)
Vitamin Intravenous, Fat-Soluble Inj.: contains vitamins A, D, E and K, 10 mL ampul (IV)
Vitamin Intravenous, Water- Inj.: contains vitamin B complex and vitamin C, 1 mL vial
Soluble and 2 mL ampul (IV)
Vitamin K1 (see
Phytomenadione)
44
W
Warfarin (as sodium salt) (1, 2) Oral: 1 mg, 2.5 mg and 5 mg tablet
Y
Yellow Fever Vaccine Inj.: 1000 DL 50 mouse min (attenuated) vial + 0.5 mL
solvent syringe (IM, SC) (For Bureau of
Quarantine Use Only)
Z
Zidovudine Oral: 100 mg capsule
300mg tablet
50mg/5mL suspension, 240mL per bottle
Zinc Oral: chewable tablet, (equiv. to 10 mg elemental zinc) (as
gluconate)
tablet, (equiv. to 30 mg elemental zinc) (as
gluconate trihydrate)
88mg dispersible tablet (equivalent to 20mg zinc)
(as sulfate)
solution, (equiv. to 10 mg elemental zinc/mL) drops,
15 mL, (as sulfate monohydrate)
solution, (equiv. to 20 mg elemental zinc/5 mL)
syrup, 60 mL (as sulfate monohydrate)
70 mg/5 mL syrup (equivalent to 10 mg elemental
zinc), 60 mL and 120 mL (as gluconate)
Zolmitriptan Oral: 2.5 mg tablet
Zolpidem (A1) Oral: ⊗10 mg tablet
RESTRICTED ANTIMICROBIALS
Amphotericin B