Name:______________________ Unit 12 Packet

Unit 12.1: DNA The Genetic Material

Vocabulary
1. Double Helix:
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2. Nucleosome:
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Section Assessment
1. Summarize the experiments of Griffiths & Avery that indicated that DNA is the genetic material:
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2. Describe the data used by Watson and Crick to determine the structure of DNA:
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3. Draw and label a segment of DNA showing its helix and complementary base pairing:

4. Describe the structure of eukaryotic chromosomes:

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 Unit 12.2: Replication of DNA
Vocabulary
1. Semiconservative Replication:
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2. DNA Polymerase:
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3. Okazaki Fragment:
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Section Assessment
1. Indicate the sequence of the template strand if a non-template strand has the sequence
5’ ATGGGGCGC 3’:
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2. Describe the role of DNA Helicase, DNA Polymerase, & DNA Ligase in DNA replication:
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3. Draw a diagram showing the difference in the way leading and lagging strands are synthesized:
 Unit 12.3: DNA, RNA, & Protein
Vocabulary
1. RNA:
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2. Messenger RNA:
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3. Ribosomal RNA:
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4. Transfer RNA:
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5. Transcription:
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6. RNA Polymerase:
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7. Codon:
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8. Intron:
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9. Exon:
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10. Translation:
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 Section Assessment
1. Summarize the process by which the DNA code is made into a protein:
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2. Describe the function of each of the following in protein synthesis:
-rRNA:_____________________________________________________________________________
-mRNA:____________________________________________________________________________
-tRNA:_____________________________________________________________________________
3. Differentiate between codons and anti-codons:
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4. Explain the role of RNA Polymerase in mRNA synthesis:
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 Unit 12.4: Gene Regulation & Mutation
Vocabulary
1. Gene Regulation:
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2. Operon:
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3. Mutation:
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4. Mutagen:
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Section Assessment
1. Relate gene regulation and mutation:
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2. Identify the two main types of mutagens:
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3. Diagram how adding lactose to a culture affects the lac operon of E. coli:

4. Analyze how a point mutation can affect the overall protein shape and function using hemoglobin as an
example:
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5. Compare and contrast prokaryotic & eukaryotic gene regulation:
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