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Maricela Escamilla
HLTH 1050
04/01/2019
Research Paper
(1)
Opium poppy also known as Papaver Somniferum L. Is a plant that is well known
throughout the nation and history. Grown in the Mediterranean region starting shown as early as
5000 B.C. The legal production for medicinal use is taking place in India, Australia, and Turkey,
whom produce about two thousand tons to supply the raw material to the world. The sap, that
contains alkaloids, that includes codeine and morphine, oxycodone, and heroin known as opiates.
The effects on a human body can range from euphoria, addiction, pain relief, cough suppression,
bowl relief and induce sleep. For medical physician they are the most cost effective and best
treatment for severe pain relief. The negative effects of using opiates can be respiratory
depression, slurred speech, sexual dysfunction, vomiting, increased pressure in the brain, and
more. Now, if mixed with non-sterile needles and other drugs mixed with opiates then the side
effects would include lung, brain, and skin abscesses, infected and collapsed veins, HIV and
Hepatitis, and or endocarditis. Not only is the poppy used for medicinal purposes but can be used
for culinary purposes, the poppy seed can be used for flavoring lemon cake, bagels, and muffins.
Although, the opium content is minimal when consuming the poppy seeds items, it can result
positive on a drug test. (2) The opium can be taken in a pill form, which may or may not be
combined already with other drugs, smoked, sniffed, injected intravenously. The physical
fine brown powder. Most common names would be Big O, Black Pill, Joy plant, Midnight oil,
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and more. The reaction to the body can vary but is shown to cause dry mouth, constipation, and
mucous membrane in the nose. As well as leads in the to physical and psychological dependence,
often times leads to overdose. The overdose effects can be loss of consciousness, coma, seizures,
and possible death. (3) Which brings us to the opiate derivatives that were formed from the opium
poppy plant, the following included are morphine, codeine, heroin, thebaine, and oripavine. The
most powerful being morphine and heroine, appearing in large quantities within the plant. Not
only were opiates made but also synthetic opiates derivatives were created. Those include
fentanyl, lortab, norco and more. (4) According to the National Survey on Drug Use and Health
(NSDUH), about 948,000 Americans were reported using heroin within the past year of 2016.
That has been and strikingly increasing since the year 2007, mostly from young adults ranging
from 18-25-year old. Luckily, among the youth the use has been declining ages ranging from 12-
17-year old being the lowest levels since the year 1991. With Heroin use on the continuing to
rise, the number of dependencies on heroin have increased and been meeting in the manual of
mental disorder in the diagnostic and statistics. It demonstrated that in the year of 2002 214,00
heroin use disorder inclined to 626,000 in 2016. Clearly showing that the impact of heroin is
shown not only across the United States but as well as coast to coast.
(5)
Heroin did not just stop in the United States but in England it has also been a
continuous battle. The Office for National Statistics have shows that deaths from heroin and
morphine have increased from 579 deaths to 952 death in the span of two years, starting from the
year 2012 that is an increase of 64%. The incline is due to various factors such as availability,
purity, and lower pricing. As well, as the mixing of other substances with the heroin, such as
alcohol, cocaine, or and methadone. Scotland has also seen a rise in deaths that included heroin
While opiates are still common, the synthetic derivatives are also sweeping the nation,
slowly replace heroin due to the cost, or possibly due to the availability. One of the most
terrifying drugs is known as the Krokodil, it commonly listed under the world’s deadliest drug.
The reason is due to the making of the product not the opioid content necessarily. The opioid
times stronger compared to morphine. The reason for its terror is due the rapid onset when
injection the product only lasting briefly in comparison to heroin, this causes users to constantly
having to repeatedly inject continuously. This creates the users and their bodies to become
physical dependent, addicted, and create tolerance towards the drug. The worst part is that drug
has been shown to be flesh-eating bacterial infections. The DEA stated that for long-term users,
the skin appears to be like of a crocodile’s green scaled skin, hence the reason for the name. This
is due the result of blood vessel damage of the injection site. Also, causing thrombosis,
ulceration, necrosis, damage to the soft tissues, thrombophlebitis, and gangrene. Usually
resulting in amputation of the limb or possibly death. (7) The drug originally appeared in Russia,
specifically Siberia, then has spread nation wide from there. It was made due to Russia’s severe
heroin addiction, when one could no longer afford heroin, they had the ability to make the
krokodil drug. The drug itself is more potent and cost around a tenth of the price compared to
heroin. However, this comes at a deadly price, a Moscow heroin addict life expectancy is four to
seven years. An addict of Krokodil life expectancy is only a year or two. The primary reason is
because of the ingredients and process of making krokodil. Any drug addict can make this
ingredient by acquiring paint thinner, iodine, codeine (sold over the counters for headaches),
gasoline, red phosphorous (from match box strike pads, and hydrochloric acid. Once cooked with
paint thinner it the concoction will result in a liquid form which can then be injected
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intravenously. It only takes about 30 minutes to make, this high can last from 90 minutes to two
hours. Now the withdrawal differs from heroin as too, for example heroin’s withdrawal causes
pain and sickness for about ten days. Krokodil’s withdrawal causes extreme unbearable pain that
to avoid the addict from passing out they are injected with potent tranquilizers during the
withdrawal process. Doctors that are in charge of the Krokodil addicts say that this is the hardest
to cure and if they manage to get clean, they may be left with speech impediment, erratic
movements, and vacant gaze. Two regional governors stated that the krokodil drug accounts for
half of their addictions and deaths that are drug related. Making it the drug of choice nearly
replacing opiates.
(8)
In the state of Arizona there has only been two cases so far in the United States that
confirmed the drug krokodil was used. The co-director at Banner Good Samaritan Poison and
Drug Information Center located in Arizon, Dr. Frank LoVecchio confirmed that there were two
cases in Arizona. Although, he declined to comment on the patient’s conditions due to HIPAA
he did stated he was extremely frightened. He also stated the following “As far as I know, these
are the first cases in the United States that are reported.” Another Dr named Aaron Skolin, a
toxicologist at Banner Good Samaritan Poison and Drug Information Center mentioned that
“This is something we hoped would never make it to the U.S because it’s so detrimental to the
people who use it.” Since then more doctors have been commenting about the issues of krokodil
such as Dr. Ellen Marmur, chief of dermatological and cosmetic surgery in the Mount Sinai
Medical Center in New York City. She stated that she had never seen cases that krokodil was
involved in. But it did remind her of “skin popping,” when drug users typically inject
intravenously a substance into their skin directly due to damaged veins. This was done back in
the day and it is just killing the skin, stating you are only seeing large dead pieces of skin. The
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large parts of skin are known as eschars, which now leaves the user prone to amputation, other
complication, and infections. Marmur stated she was initially concerned that the drug could
make its way to the U.S. To some other doctors there is no concern over krokodil making it’s
way to over the U.S. Like Dr. Lewis Nelson, whom is a medical toxicologist at Bellevue
Hospital Center in New York, stated in the year of 2011 that he doubted krokodil would
eventually reach the United States because the availability of other drugs who are inexpensive
and more potent like black tar heroin and oxycontin. He also assured that “It’s not going to
become a club drug, I can guarantee you that.” So far I have not been able to find anymore cases
Works Cited
(3) List Of Opiates That Are Derived from the Opium Poppy
http://www.opium.org/list-opiates-derived-opium-poppy.html
(5) Wise, Jacqui. “Heroin Deaths Increase by Two Thirds in Two Years, UK Figures
Show.” BMJ: British Medical Journal, vol. 351, 2015. JSTOR,
www.jstor.org/stable/26521675.