Title (en)

PHARMACEUTICAL FORMULATIONS

Publication
EP 0095897 B1 19881123 (EN)

Application
EP 83303034 A 19830525

Priority
  • GB 8215684 A 19820528
  • GB 8313036 A 19830512

Abstract (en)
[origin: EP0095897A2] Topical formulation contains pseudomonic acid (I) or its salt or ester and at least 1 wt.% of a poly (opt. substd. alkylene)
glycol (II) or its deriv. Pref. salts of (I) are the alkali metal salts and pref. esters are the 1-4C alkyl esters. The formulation pref. contains 0.01-50 wt.
% (I) (or salt or ester). Pref. (II) is polyethylene glycol (PEG) or its deriv. (esp. PEG 400 opt. contg. PEG 4000, glycofurol or cetomacrogol). The
formulation may also contain antibacterial, antifungal, antiviral and/or antiinflammatory agents but pref. (I) is the sole therapeutic agent. Use amt. of
(I) is esp. 0.5-10 (partic. 2) wt.%.S (I) is a known antibiotic (see GB1395907) useful for treating skin, ear and eye disorders by topical admin. (I) has
improved stability in presence of (II). -

IPC 1-7 (main, further and additional classification)

A61K 9/06; A61K 31/35; A61K 47/00

IPC 8 full level (invention and additional information)

A61K 31/35  (2006.01); A61K 47/10  (2006.01); A61K 47/22  (2006.01)

CPC (invention and additional information)

A61K 31/35 (2013.01); A61K 9/0014 (2013.01); A61K 47/10 (2013.01); A61K 47/22 (2013.01)

Citation (examination)
Cosmetics, Science and Technology, Ed. M.S. Balsam and E. Sagarin, New York, London, Sydney, Toront o, Sec. Ed. Vol. 1, pp
186, 187, 194, 195, 205, 233, 235, 236

Cited by
EP0493404A4; US6489358B2; US5985291A; EP0430149A3; US5118698A; US6156792A; EP0251434A3; US6001870A; AU724070B2;
US5594026A; US5397771A; US5428006A; US5693608A; EP0231621A3; US6214866B1; US6426363B1; WO9210493A1; WO0147542A1;
WO9814189A1; WO9116929A1

Designated contracting state (EPC)

BE CH DE FR GB IT LI NL SE

DOCDB simple family

EP 0095897 A2 19831207; EP 0095897 A3 19841212; EP 0095897 B1 19881123; AU 1488583 A 19831201; AU 555897 B2 19861016; CA
1196284 A 19851105; DE 3378523 D1 19881229; HK 21991 A 19910328; IE 55243 B1 19900718; IE 831205 L 19831128; NZ 204326 A
19850913; US 4524075 A 19850618