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SECTION 1. IDENTIFICATION
Telephone : 1-800-428-5074
Emergency telephone
In case of emergencies: : CHEMTREC 1-800-424-9300 (U.S. or Ca-
nada)
1-703-527-3887 (Internatio-
nal)
Recommended use of the chemical and restrictions on use
Restrictions on use : For professional users only.
Hazardous ingredients
Chemical name CAS-No. Concentration (% w/w)
1,3-Propanediol, 2,2-bis(hydroxymethyl)- 115-77-5 >= 10 - < 20
Methanaminium, N,N,N-trimethyl-, chloride 75-57-0 >= 0.1 - < 1
(1:1)
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SAFETY DATA SHEET
Suitable extinguishing media : Use extinguishing measures that are appropriate to local cir-
cumstances and the surrounding environment.
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SAFETY DATA SHEET
Methods and materials for : Pick up and arrange disposal without creating dust.
containment and cleaning up Sweep up and shovel.
Keep in suitable, closed containers for disposal.
Advice on protection against : Provide appropriate exhaust ventilation at places where dust
fire and explosion is formed.
Conditions for safe storage : Electrical installations / working materials must comply with
the technological safety standards.
Hand protection
Hygiene measures : Handle in accordance with good industrial hygiene and safety
practice.
Odor : characteristic
pH : 6.9
Concentration: 100 g/l
(as aqueous solution)
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SAFETY DATA SHEET
Solubility(ies)
Water solubility : soluble
Viscosity
Viscosity, dynamic : Not applicable
1,3-Propanediol, 2,2-bis(hydroxymethyl)-:
Acute oral toxicity : LD50 Oral (Mouse): 25,500 mg/kg
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SAFETY DATA SHEET
Skin corrosion/irritation
Not classified based on available information.
Ingredients:
1,3-Propanediol, 2,2-bis(hydroxymethyl)-:
Species : Rabbit
Result : No skin irritation
1,3-Propanediol, 2,2-bis(hydroxymethyl)-:
Species : Rabbit
Result : No eye irritation
Skin sensitization
Not classified based on available information.
Respiratory sensitization
Not classified based on available information.
Ingredients:
1,3-Propanediol, 2,2-bis(hydroxymethyl)-:
Species : Mouse
Method : OECD Test Guideline 429
Result : Did not cause sensitization on laboratory animals.
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SAFETY DATA SHEET
Ingredients:
1,3-Propanediol, 2,2-bis(hydroxymethyl)-:
Genotoxicity in vitro : Test Type: Ames test
Test system: Salmonella typhimurium
Method: OECD Test Guideline 471
Result: negative
Carcinogenicity
Not classified based on available information.
Ingredients:
1,3-Propanediol, 2,2-bis(hydroxymethyl)-:
Species : Rat
Application Route : Oral
Group : yes
NOAEL : 1,000 mg/kg bw/day
Result : negative
IARC No ingredient of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
OSHA No component of this product present at levels greater than or equal to 0.1% is
on OSHA’s list of regulated carcinogens.
NTP No ingredient of this product present at levels greater than or equal to 0.1% is
identified as a known or anticipated carcinogen by NTP.
Reproductive toxicity
Not classified based on available information.
STOT-single exposure
Not classified based on available information.
Ingredients:
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SAFETY DATA SHEET
STOT-repeated exposure
Not classified based on available information.
Repeated dose toxicity
Ingredients:
1,3-Propanediol, 2,2-bis(hydroxymethyl)-:
Species : Rat
NOAEL : 100 mg/kg
Application Route : Oral
Group : yes
Symptoms : Diarrhea
Remarks : No significant adverse effects were reported
Aspiration toxicity
Not classified based on available information.
Further information
Ingredients:
Ingredients:
1,3-Propanediol, 2,2-bis(hydroxymethyl)-:
Toxicity to fish : LC50 (Leuciscus idus (Golden orfe)): > 5,000 mg/l
Exposure time: 48 h
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SAFETY DATA SHEET
Toxicity to daphnia and other : EC50 (Daphnia magna (Water flea)): 38,900 mg/l
aquatic invertebrates Exposure time: 24 h
Toxicity to daphnia and other : EC50 (Daphnia magna (Water flea)): 0.16 mg/l
aquatic invertebrates Exposure time: 11 d
GLP: yes
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SAFETY DATA SHEET
Ecotoxicology Assessment
Chronic aquatic toxicity : Toxic to aquatic life with long lasting effects.
Ingredients:
1,3-Propanediol, 2,2-bis(hydroxymethyl)-:
Biodegradability : Result: Inherently biodegradable.
Biodegradation: 99 %
Exposure time: 28 d
Method: OECD Test Guideline 301
Bioaccumulative potential
Ingredients:
1,3-Propanediol, 2,2-bis(hydroxymethyl)-:
Partition coefficient: n- : log Pow: -1.7 (22 °C / 22 °C)
octanol/water
Mobility in soil
No data available
Other adverse effects
Disposal methods
Waste from residues : Special treatment as infectious material is mandatory in com-
pliance with local regulations (disinfection and incineration).
Can be disposed as waste water, when in compliance with
local regulations.
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SAFETY DATA SHEET
International Regulations
UNRTDG
Not regulated as a dangerous good
IATA-DGR
Not regulated as a dangerous good
IMDG-Code
Not regulated as a dangerous good
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable
Domestic regulation
49 CFR
Not regulated as a dangerous good
SARA 313 : This material does not contain any chemical components with
known CAS numbers that exceed the threshold (De Minimis)
reporting levels established by SARA Title III, Section 313.
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SAFETY DATA SHEET
The following chemical(s) are listed under the U.S. Clean Air Act Section 111 SOCMI Intermedi-
ate or Final VOC's (40 CFR 60.489):
1,3-Propanediol, 2,2- 115-77-5 >= 10 - < 20 %
bis(hydroxymethyl)-
Sodium acetate trihy- 6131-90-4 >= 1 - < 5 %
drate
Clean Water Act
The following Hazardous Substances are listed under the U.S. CleanWater Act, Section 311, Ta-
ble 116.4A:
Iron(II) sulfate heptahy- 7782-63-0 >= 0 - < 0.1 %
drate
Copper(II) sulfate, pen- 7758-99-8 >= 0 - < 0.1 %
tahydrate
The following Hazardous Chemicals are listed under the U.S. CleanWater Act, Section 311, Table
117.3:
Iron(II) sulfate heptahy- 7782-63-0 >= 0 - < 0.1 %
drate
Copper(II) sulfate, pen- 7758-99-8 >= 0 - < 0.1 %
tahydrate
This product does not contain any toxic pollutants listed under the U.S. Clean Water Act Section
307
US State Regulations
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SAFETY DATA SHEET
Dextrose
Creatine monohydrate
Ficoll 70
Creatine kinase
Alanine aminotransferase
Acid phosphatase
Alkaline phosphatase
Aspartate aminotransferase
.alpha.-Amylase
Triacylglycerol lipase
.gamma.-Glutamyltransferase
Dehydrogenase, glutamate
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SAFETY DATA SHEET
TSCA list
No substances are subject to a Significant New Use Rule.
Further information
Cfas USA F1-oSw
NFPA: HMIS® IV:
Flammability
HEALTH / 0
0
FLAMMABILITY
Instability
0
Health
0 0
PHYSICAL HAZARD
0
AICS - Australian Inventory of Chemical Substances; ASTM - American Society for the Testing of
Materials; bw - Body weight; CERCLA - Comprehensive Environmental Response, Compensation,
and Liability Act; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standard of the
German Institute for Standardisation; DOT - Department of Transportation; DSL - Domestic Sub-
stances List (Canada); ECx - Concentration associated with x% response; EHS - Extremely Haz-
ardous Substance; ELx - Loading rate associated with x% response; EmS - Emergency Schedule;
ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration associated with
x% growth rate response; ERG - Emergency Response Guide; GHS - Globally Harmonized Sys-
tem; GLP - Good Laboratory Practice; HMIS - Hazardous Materials Identification System; IARC -
International Agency for Research on Cancer; IATA - International Air Transport Association; IBC
- International Code for the Construction and Equipment of Ships carrying Dangerous Chemicals
in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organiza-
tion; IECSC - Inventory of Existing Chemical Substances in China; IMDG - International Maritime
Dangerous Goods; IMO - International Maritime Organization; ISHL - Industrial Safety and Health
Law (Japan); ISO - International Organisation for Standardization; KECI - Korea Existing Chemi-
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SAFETY DATA SHEET
cals Inventory; LC50 - Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to
50% of a test population (Median Lethal Dose); MARPOL - International Convention for the Pre-
vention of Pollution from Ships; MSHA - Mine Safety and Health Administration; n.o.s. - Not Oth-
erwise Specified; NFPA - National Fire Protection Association; NO(A)EC - No Observed (Adverse)
Effect Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable
Effect Loading Rate; NTP - National Toxicology Program; NZIoC - New Zealand Inventory of
Chemicals; OECD - Organization for Economic Co-operation and Development; OPPTS - Office
of Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic sub-
stance; PICCS - Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quanti-
tative) Structure Activity Relationship; RCRA - Resource Conservation and Recovery Act;
REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concern-
ing the Registration, Evaluation, Authorisation and Restriction of Chemicals; RQ - Reportable
Quantity; SADT - Self-Accelerating Decomposition Temperature; SARA - Superfund Amend-
ments and Reauthorization Act; SDS - Safety Data Sheet; TCSI - Taiwan Chemical Substance
Inventory; TSCA - Toxic Substances Control Act (United States); UN - United Nations; UNRTDG -
United Nations Recommendations on the Transport of Dangerous Goods; vPvB - Very Persistent
and Very Bioaccumulative
The information provided in this Material Safety Data Sheet is correct to the best of our
knowledge, information and belief at the date of its publication. The information given is designed
only as a guidance for safe handling, use, processing, storage, transportation, disposal and re-
lease and is not to be considered a warranty or quality specification. The information relates only
to the specific material designated and may not be valid for such material used in combination
with any other materials or in any process, unless specified in the text.
US / Z8 / 1711
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