Koplan NAPLEX Practice Quiz Question #2 Patient Name: Kirk Johns ‘Address: 123 Camden Drive ‘Age: 66 Sex Male Height: 5 Weight: 182 Ibs (82.7 kg) Allergies: Opioids Diagnoses: + Type 1 Diabetes + Chronic Atrial Fibrillation + Glaucoma Medication Record Rx Date Quantity Sig Refills Number Strength 10087136 8/17 George Warfarin. 30 1qd 5 5mg 10087137 8/17 George —Xalatan 2.8 tou § > 0.005% HS 10087138 8/17 George —Tovjeo 10 uaD 5 10087139 8/17 George Apidra=-20 uaD 5 10087140 8/17 George Insulin 100 VAD 5 needles 316 10087141 8/17 George Glucagon 3 vad 5 Laboratory Tests (Normal values) 8g ‘Sodium (135 - 147 mEgiL) 141 mEgiL Potassium (3.5 - 5.2 mEq/L) 43 mEq/L. Chloride (95 - 107 mEq/L) 101 mEq/L Calcium (8.8 - 10.3 mg/dL) 9.9 mEqIL Albumin (3.2 - 5 g/dL) 3.8 gid hitp:tkaplanguizzes.comreviewinaplex/7success=yes 14spsroig Koplan NAPLEX Practice Quiz ‘Serum Creatinine (0.5 -1.4 mg/dL) 2.1 mg/dL. BUN (7 - 20 mg/dL) 19 mg/dl. Total Cholesterol (< 200 mg/dl) 228 mg/d HDL Cholesterol (> 35 mg/dl) 44 mgidL. LDL Cholesterol (65 - 180 mg/dl) 155 mg/dL Triglycerides (< 150 mg/dL) 144 mgldL. AST (< 35 IU/L) 19 IU/L ALT (< 35 1U/L) 47 IAL Glucose, fasting (60 - 110 mg/dl) 188 mg/dl. Atc (<6 %) 10.0% Blood pressure (120/80 mmHg) 112/72 mmHg Heart Rate (60 - 100 BPM) 82BPM Temperature (97.8 F - 99 F / 36.5 C -37.2.C) 98.7 F ‘Additional info: No pharmacist notes 2) When Mr. Johns administers his Toujeo prior to breakfast (7:30 am), it will exert its peak effect A. almost immediately. B. between breakfast and lunch (at noon), C. during lunch (at noon) D. between lunch (noon) and dinner (5 pm). E. This medication does not exert a peak effect. Answer: ‘The correct answer is E. This is a commonly encountered patient counseling ‘question in which a pharmacist is asked to explain the duration J peak effect for an insulin product. n this case, the patient is receiving insulin glargine (Toujeo @) and the question is asking for its peak effect. A summary table of selected insulin products is provided below. Insulin Products hitp:tkaplanguizzes.comreviewinaplex/7success=yes 28spsroig Insulin Preparation Rapid-acting Ins + Lispro (Humatog®) + Aspartate (NovoLog®) + Glulisine (Apidra®) Regular Insulin NPH Insulin Long-acting Ins + Deter (Levemire) + Glargine U- 100 (Lantus®) + Glargine U- 300 (Toujeo®) + Glargine U- 300 (Toujeos) + Insulin degludec (Tresiba @) hitp:tkaplanguizzes.comreviewinaplex/7success=yes Kaplan NAPLEX Practice Quiz Onset of Peak Duration Action Effect of Action 515 12hours 45 minutes hours 20-60 24hours 8-10 minutes hours 4-2 4-8 hours 10-20 hours hours 12 Relatively 20-24+ hours flat/no hours peak Other Notes + Take immediately before or with a meal + Clear preparation + Inject 30 minutes prior to meal + Clear preparation + Use with meal occurring 4 hours after the dose + Cloudy preparation + Take insulin same time each day + Clear preparation as