3.

FLOW PATH DIAGRAMS

3-1 List of Solenoid Valves, Pumps, Fans and Heaters.................................................... 3-1

3-2 Overall Piping Diagram ................................................................................................. 3-3

3-3 Water Tank ...................................................................................................................... 3-4

3-4 Wash ................................................................................................................................ 3-6

3-5 CARRY OVER EVASION Function ................................................................................ 3-10

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3. FLOW PATH DIAGRAMS

3-1 List of Solenoid Valves, Pumps, Fans and Heaters

Table 3-1

No. Class SV/P No. Type AC/DC Application Part No.

1 Solenoid valve SV1 UDV2-M6-C 24 V DC For sample syringe 736-7130

2 ↑ SV2 ↑ ↑ For R1 syringe 736-7130

3 ↑ SV3 ↑ ↑ For R2 syringe 736-7130

4 ↑ SV4 ↑ ↑ For external washing of S 707-0320

nozzle
5 ↑ SV5 ↑ ↑ For external washing of R1 707-0320
nozzle

6 ↑ SV6 ↑ ↑ For washing of stirring 707-0320

rod (R1, R2)

7 ↑ SV7 CKD 24 V DC For supply of cell rinse 707-0290

A2-5619 water

8 ↑ SV8 ↑ ↑ For water supply 707-0288

9 ↑ SV9 UDV2-M6-C 24 V DC For external washing of R2 707-0320

nozzle

10 ↑ SV10 ↑ ↑ For supply of water to 707-0320

incubation bath

11 ↑ SV11 ↑ ↑ For washing of cell rinse tip 707-0320

12 ↑ SV12 MTV ↑ For supply of cell detergent 704-0365

13 ↑ SV13 CKD ↑ For degassing unit 707-0289

A2-5619

14 ↑ SV14 MTV-31-M6 ↑ For supply of cell detergent 704-0366

15 ↑ SV15 UDV2-M6-C 24 V DC For supply of cell blank 707-0320

water

16 ↑ SV16 CKD For draining incubation bath 707-0289

A2-5619 water

17 ↑ SV21 NTV-2-HN DC For vacuum 707-0286

18 ↑ SV30 ↑ ↑ For dilute waste solution 707-0286

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3. FLOW PATH DIAGRAMS ________________________________________________________

No. Class SV/P No. Type AC/DC Application Part No.

19 Solenoid valve SV31 NTV-2-HN DC For concentrated waste 707-0286

Fan solution

20 Pump MP1 MD-10NG 100 V AC For circulation of incubation 717-0241

bath water

21 ↑ MP2 MGH-100 ↑ For water supply 707-0306

22 Vacuum pump VP1 DAP-15 ↑ For suction 707-0282

23 Solenoid valve ISV1 MTV-2 24 V DC REF (IN) 707-0414

for ISE SM6D

24 ↑ ISV2 MTV-31-M6 ↑ DIL waste solution 707-0415

25 ↑ ISV3 NTV-2-HN ↑ ISE waste solution 707-0414

26 ↑ ISV5 MTV-21-SM6M ↑ ISE waste solution vacuum 707-0414

27 ↑ ISV6 MTV-2-SM6D ↑ DIL syringe (OUT) 707-0414

28 ↑ ISV7 ↑ ↑ IS syringe (OUT) 707-0414

29 ↑ ISV8 ↑ ↑ Between SIP and REF 707-0414

30 ↑ ISV9 ↑ ↑ DIL syringe (IN) 707-0414

31 ↑ ISV10 ↑ ↑ IS syringe (IN) 707-0414

32 ↑ ISV11 ↑ ↑ SIP syringe 707-0414

33 ↑ ISVPV AP-2602-13-H ↑ SIP pinch valve 707-0416

34 Fan — MU1225M-11N 100 V AC For bio-hazard 707-0408

35 ↑ — ↑ ↑ For electrical system 707-0408

36 ↑ — ↑ ↑ For mechanical system 707-0408

37 Heater HEA 1 Cartridge heater 100 V AC For degassing 707-0292

38 ↑ HEA 2 ↑ ↑ ↑ 707-0293

39 ↑ HEA 3 ↑ ↑ For incubation bath 707-0291

For cooling reagents 707-1445
40 Cooling unit — — ↑
and samples
R1/R2 bar code window 707-0287
41 Window heater — — 5 V AC
heater
42 ISE solenoid (S) — SD08AA 24 V DC For ISE sipper nozzle 707-0417
For ISE waste solution 707-0418
43 ISE solenoid (V) — SD10BBA ↑
nozzle
(v)

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 ___________________________________________________________________________________________________________________________________________________________ 3. FLOW PATH DIAGRAMS
3-2 Overall Piping Diagram

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 ________________________________________________________3. FLOW PATH DIAGRAMS

3-3 Water Tank

Function : The degasser unit is sterilized by heat.

Required time: 15 minutes

(1) Processing Flow

Processing No. Description

1 2 Start up through the MAINTENANCE screen.

3 Refer to the next sheet.

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3. FLOW PATH DIAGRAMS ________________________________________________________

(2) Processing Details of Water Tank Processing

3-5 ______________________________________________________________________________
 ________________________________________________________3. FLOW PATH DIAGRAMS
3-4 Wash
Function :
All the cells are washed. The sample probe is washed with NaOH, and the stirring
mechanism is washed in the cell containing HITERGENT.
(The ISE mechanism is cleaned.)
Required time: 1492 seconds (16 seconds for resetting + 6 seconds/cycle X 246)
(1) Processing Flow

Processing No. Description

1 Start up through the 05-01 ANALYZER MAINTENANCE screen.
(WASH: CELLS, ISE, or ALL)
2 Refer to the next sheet.
3 Operation check is carried out in washing. If any abnormality is found, the relevant alarm is
indicated on the OPERATION MONITOR screen.
4 The above alarm data is stored into the I/O RAM.

Remarks: (1) Details of Startup and Operation

(a) If ‘CELLS’ is specified for ‘WASH’ ... All the cells, sample probes (R1 and R2), and stirring mechanisms (R1
and R2) are rinsed.
(b) If ‘ISE’ is specified for ‘WASH’ ... The ISE mechanism is rinsed.
(c) If ‘ALL’ is specified for ‘WASH’ ... The above washing sequences (a) and (b) are carried out at the same time.
Note: Where the ISE mechanism is not provided:
If ‘ISE’ is specified for ‘WASH’ ... On-screen input is not permitted.
If ‘ALL’ is specified for ‘WASH’ ... The washing sequence for ‘CELLS’ is carried out.

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3. FLOW PATH DIAGRAMS ________________________________________________________

(2) Details of Wash Processing

Processing

*1. For 1, 2, 3 and 4, refer to the next sheet.

*2. Refer to the ISE maintenance timing chart. (With this function, detergent aspiration and preparation are repeated ten times, respectively.)
*3. This function is carried out on a six-seconds-per-cycle basis. Note, however, that one cycle of sample probe washing is 30 seconds and
one cycle of ISE washing is 10 seconds.

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 _________________________________________________________3. FLOW PATH DIAGRAMS

(a) Rinsing mechanism

(b) R1/R2 reagent probe mechanism

(c) 1st/2nd stirring mechanism

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3. FLOW PATH DIAGRAMS _______________________________________________________

(d) Serum sampling mechanism

3-9 ______________________________________________________________________________
 _________________________________________________________ 3. FLOW PATH DIAGRAMS

3-5 CARRY OVER EVASION Function

(1) This function is intended to prevent unreliable data due to carry-over between reagents and between
samples.
For this purpose, washing is carried out between reagents or between samples where carry-over
occurs.
The following 4 types of washing are available.
(a) Washing of reagent carry-over from R1 probe
(b) Washing of reagent carry-over from R2 probe
(c) Washing of reagent carry-over from cell
(d) Washing of sample carry-over from sample probe

(2) Washing of Reagent Carry-over from R1 Probe

When the specified R1 and R4 sampling patterns appear on the analyzer, carry-over is prevented by
washing the R1 probe between the patterns.
The probe is washed by 1 aspirating detergent set on the reagent disk and discharging it into the cell or
2 discharging water alone into the cell.
At this time, stirring is also performed.

(3) Washing of Reagent Carry-over from R2 Probe

When the specified R2 and R3 sampling patterns appear on the analyzer, carry-over is prevented by
washing the R2 probe between the patterns.
The probe is washed in the same manner as in (2) above.

(4) Washing of Reagent Carry-over from Cell

Carry-over is prevented by rinsing the cell used for washing-specified test analysis as an empty cell at
the next sample discharge timing.
The cell is rinsed by 1 aspirating detergent set on the reagent disk and discharging it into the cell or 2
discharging water alone into the cell.
At this time, stirring is also performed.

(5) Washing of Sample Carry-over from Sample Probe

Sample carry-over is prevented by washing the sample probe.

Washing is carried out in the following conditions: 1 upon changeover between the sample for which
the washing-specified test is requested and the previous sample, and 2 upon request for stat sample
measurement during analysis of samples for which the washing-specified test is requested.
The sample probe is washed by aspirating 50 µL of detergent from the specified detergent cup on the
sample disk, discharging it into the rinse bath and rinsing with water.
At this time, stirring is not performed.
This washing is not carried out for control sample or STD sample.

(6) Priority for Carry-over Washing

The priority when the timing for various types of washing overlaps is as follows.
(a) Cell rinsing > R1/R2 probe washing (To be carried out in the next cycle)
(b) Simultaneous execution of sample probe washing and cell rinsing or R1/R2 probe washing

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3. FLOW PATH DIAGRAMS ________________________________________________________
(7) Carry-over Washing Schedule

S : Chemistry STD
A,B,C,D : Chemistry CH
I : ISE
E : Empty
W1 : : R1 probe washing
W2 : : R2 probe washing

WC : Cell carry-over washing

:
: Sample carry-over washing
WS

(a) R1 Probe Washing

Example (when all are assigned to cell no. 1)

Washing pattern
Schedule Conditions Schedule

R1 → R1 A C . . . . R1, R4 R1 is used on channel

(A) (B) B . . . . R1 B corresponding to cell no.
120. Since discharge is
already made 10 minutes
before, the washing pattern
sequence is not carried out.

R1 → R4 Cell no. 61 cannot be emptied

(A) (C) because test C was assigned
about 10 min. ago.

Washing pattern is avoided

R4 →R1
(C) (B)

R4 →R4 Washing is caried out when

(A) (C) previously assigned R4 test
and the one to be assigned
this time are tests for which
carry-over washing is specified.
Washing is make even when
washing pattern is not constituted
because R1 is entered later.
(Channel B corresponding to cell no. 2)

With respect to R1 probe, R4 on channel A or R1 on

channel B is discharged in a certain analytical cycle.
(In one analytical cycle, either R1 or R4 is discharged.)

3-11 _____________________________________________________________________________
 _________________________________________________________3. FLOW PATH DIAGRAMS

(b) R2 Probe Washing

Example (when all are assigned to cell no. 1)

Washing pattern
Schedule Conditions Schedule

R2 → R2 A B C . . . . R2, R3 Washing is carried out even

(A) (B) D . . . . R1 upon interrupt of R3.
Channel D corresponding
to cell no. 97 has no effect.

R2 → R3 Cell no. 40 cannot be

(B) (C) emptied because sample
is already discharged for
test C.

Washing pattern is
avoided.

R3 →R2 Washing is made even

(A) (C) upon interrupt of test
B.

R3 → R3 Washing is made even

(A) (B) upon interrupt of test
C. (R2).

With respect to R2 probe, R2 on channel A is discharged

and then R3 on channel B is discharged.
(In one analytical cycle, both R2 and R3 can be
discharged.)

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3. FLOW PATH DIAGRAMS ________________________________________________________

(c) Cell Carry-over Washing

(d) Sample Carry-over Washing

(8) Schedule Processing when R1 and R4 have the Same Discharge Timing and when Sample Pre-
dilution and R4 Discharge have the Same Timing

Channel assignment is delayed for a single cycle because pipetting operation of the R1 probe is
restricted to once per cycle.

(9) Sample Predilution

The sample once discharged into the reaction cuvette is diluted with diluent (discharged as reagent
R1) and then stirred, and a part of the sample diluted in the next cycle is further pipetted as a sample
for the next analysis.
At this time, interrupt with other samples (including stat samples) is not permitted although an empty
cell is found.

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_________________________________________________________3. FLOW PATH DIAGRAMS

(10) Schedule Processing upon Occurrence of Alarm Related to Cell Blank

If any of the following alarm related to cell blank occurs, the cell concerned is not used for analysis.
PHOTOMETER LAMP
CELL?
CELL BLANK (For details of each alarm, refer to the alarm
PASS CELL BLANK specifications.)
CELL! CELL!!
For λ1 ~ 12 and ADC 1/2, the cell concerned is not used for analysis when the difference from the
reference value is |0.1| Abs or more for the first time as well.

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