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1
Engineering Research Center for Knitting Technology, Ministry of Education, Jiangnan University, Wuxi 214122, China
2
International Joint Research Laboratory for Novel Knitting Structural Materials, Jiangnan University, Wuxi 214122, China
3
Key Laboratory of Eco-textiles, Ministry of Education, Ministry of Education, Jiangnan University, Wuxi 214122, China
*Corresponding author: mapibo@jiangnan.edu.cn
Abstract:
There are many kinds of medical textiles, such as woven textiles, non-woven textiles, braided textiles and knitted
textiles. Non-woven medical textiles constitute more than 60% of the total medical textiles used, but are almost
disposable ordinary medical textiles. While knitted fabrics forms a small part of the medical textiles, but are greatly
applied in high-tech medical textiles, containing artificial blood vessels, hernia patches, cardiac support devices,
knitted medical expandable metallic stents and tendon scaffolds. Knitting structures, including weft knitting structure
and warp knitting structure. The knitted textiles are popular for their loose structure, greater flexibility, higher porosity,
more flexible structure and better forming technology. The present article will introduce some knitting structures and
materials applied in the medical textiles in accordance with non-implantable, implantable, extra-corporeal textiles
and healthcare and hygiene products.
Keywords:
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Fig. 1. Basic pattern of weft knitting Fig. 2. Basic pattern of warp knitting
Fig. 1. Basic pattern of weft knitting Fig. 2. Basic pattern of warp knitting
Spacer monofilament
Spacer monofilament
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3 Knitted medical textiles 3.1.1.2 Weft rib stitch applied in medical dressings
3.1 Non-implantable textiles Ordinary weft rib stitch has great elasticity and extensibility
when stretching along the transverse direction. And it is
Non-implantable textiles mainly include medical dressings, difficult to generate edge-roll. While jacquard stitch, The
which
firstis surface
gauze, bandages and other textiles that come in contact with a combination of mesh stitch and rib stitch, has properties like
the skin wound. They are used to cover and protect wounds, clear patterns, stable and thick structures, as well as lower
prevent infection and promote the role of healing. extensibility and raveling property. And the different sizes of
mesh can obtain better breathability and moisture permeability.
3.1.1 Medical dressings Jacquard stitch mixes the advantages of the structures above
and greatly satisfies the requirements of medical dressings.
The action of medical dressings is to insulate and prevent
trauma, attach the drugs to the wound and absorb liquids. It is Weft rib stitch medical dressings are bioactive dressings for
essential for wound dressings to have the properties of good the application of biological materials. It contains bioactive
hygroscopicity, good breathability and great sense of comfort substances that have got the greatest attention.[5] Jutecell is
when it comes in contact with the skin. The knitted medical a new regenerated cellulose fiber with excellent antibacterial Fig. 4.Warp-kn
dressings show greater extensibility, elasticity, fitness and mildew and XOPT-Dry property. It is an ecological textile fiber
flexibility. that is new, healthy and fashionable, and has environmental
protection properties; it shows great potential in medical
For two dimensional structures, weft plain stitch and rib stitch dressings. Chitosan[6−11] is a biological material with excellent
are greatly applied in medical dressings for simple knitting properties of hemostatis, granulation, and epithelization. It has
technology, great flexibility and low viscidity. Besides these, good biocompatibility and is suitable for wounds during various
some three dimensional structures, including weft multiply healing
The phases.
first surface
composites, weft knitted spacer fabrics and warp knitted spacer
fabrics, are greatly used in the field of medical dressings. They Medical dressings based on the rib stitch can be knitted by
often have absorbent layers for good ability to control heat Jutecell/cotton blended yarn (80/20). And jacquard-rib stitch
and moisture transfer. And the materials applied in medical medical dressings can be created with Chitosan knitting mesh
dressings refer to cotton, viscose filament, alginate fiber, stitch and cotton knitting rib stitch. Fig. 6 shows the structure of
Spacer monofilament
jutecell and chitosan. Yarns and filaments take great portion for the Jacquard-rib stitch and Fig. 7 shows the knitting pattern of
little loss of short fiber during the procedure. the Jacquard-rib stitch. Fig. 5. Viscose filament yarn
The second surface
Medical dressings based on weft plain stitch show great strength, Front: Jacquard s
Back: Rib stitch
good flexibility and low viscidity. Alginate is non-toxic and aids in
homeostasis as a part of the wound healing process.[2] Medical
dressings of alginate fiber /cotton blended yarn is contact
dressing. The alginate fiber insides will form one gel layer after
Chitosan
absorbing the effusion and the gel can separate the wound from Cotton
the dressings. Cotton fibers provide enough strength to maintain
the shape and they are suitable to clad the wound. Viscose
is also applied in medical dressings. It is often combined with
non-woven materials with higher hygroscopicity to separate the
wound from short fibers of non-woven materials.[3, 4]
Fig. 6. Thestitch
Fig. 6. The structure of the Jacquard-rib structure of the Jacquard-rib stitch
Fig. 5. Viscose filament yarn knitted wound dressing fabric
4F
Back: Rib stitch Front: Jacquard stitch
3F
Chitosan 2F
Cotton
1F
1-surface layer; 2-spacer;
Fig. 6. The structure of the Jacquard-rib stitch Fig. 7. The knitting pattern of the Jacquard-rib stitch
Fig. 5. Viscose filament yarn knitted wound dressing fabric Fig. 7. The knitting pattern of the Jacquard-rib stitch
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Fig. 5. Viscose filament yarn knitted wound dressing fabric
4F
3.1.1.3 Weft Front:
multiply composites
Jacquard stitch applied in medical 3.1.2 Medical bandages
dressings 3F
Warp knitted structures, such as pillar stitch and tricot stitch,
Weft multiply composites have flexible structures with are gradually applied in medical bandages. The bandage is
different functions. The inner layer is plain stitch with dense knitted by glass fiber
2F on Italian COMEZ crocheting machine.
structures. TheChitosan
interlayer is fleecy stitch, which increases Water-soluble PVA fiber also has great potential in medical
on thickness of the dressings. And the outer layer is tuck bandages for its good biocompatibility and degradability. It
stitch with meshes, which increases both breathability and is knitted on 18-gauges DR10 EWH double needle-bar warp
aesthetics of the fabric. Cotton fiber and bamboo fiber is 1F
knitting machine. Double needle-bar tubular structures will be
generally used in multiply composite medical dressings. given good elasticity and extensity.
Bamboo fiber has excellent natural antibacterial properties,
he structurelow density,
of the good stitch
Jacquard-rib thermal insulation
Fig. 7. Theand mechanical
knitting pattern of the Jacquard-rib stitch
properties, sustainability, and biodegradability. Multiply
composites with bamboo fiber have better antibacterial
properties than cotton fiber.
Fig. 8. The structure of the multiply composites Fig. 10. The structure of the bandage knitted by glass fiber
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tricot stitch and the two bars have reverse underlap movement.
Fig. 13 (b) shows the reverse locknit stitch. And Fig. 13 (c) 3.3.2 Hernia patch
shows the combination of tricot stitch and atlas stitch with
reverse underlap movement. Fig. 12 is the actual warp-knitted Hernia patch is an important implant for hernia repair. And
artificial blood vessel. polymer meshes are frequently used in hernia surgery. Warp-
knitted pillar stitch, tricot stitch and atlas stitch are generally
The materials applied in artificial blood vessels include structures for hernia patch. Marlex® adopts tricot stitch as
polyester, polypropylene, polyethylene, polyurethane, the basic structure and Prolene® adopts atlas stitch. They
polytetrafluoroethylene and some other synthetic fibers.[19] And all have small pores.[21] Surgipro® PP hernia patch and
silk fibroin is also used for its high strength and toughness. Dexon® PGA hernia patch are created by tricot stitch and
The specifications are changeable as it is applied in different pillar stitch. The structures have higher strength and greater
occasions.[20] stability. The materials include non-absorbable polymers like
polyester, polypropylene, expanded polytetrafluoroethylene,
polyvinylidenefluoride and absorbable polymers polyglycolic
acid.[22]. Fig. 14 shows two hernia patches made of
polypropylene. Fig. 14 (a) is Marlex® patch with small pores
and Fig.14 (b) is Vypro® patch with large pores.
(a) (b)
Fig. 14. The actual structures of hernia patch. (a) Marlex® patch; (b) Vypro® patch
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the ligament has different sizes and they are used for different 3.2.5 Urethral suspension sling
situations.[27] LARS ligament has lower extensibility, higher
tensile strength,Fig. 14. The actual structures of hernia patch. (a) Marlex® patch; (b) Vypro® patch
great fatigue strength and satisfactory clinical The sling used in suspension is warp-knitted mesh fabric.[32,33]
results.[28] Fig. 17 (a) shows the fabric with small meshes and the structure
is tricot stitch. Fig. 17 (b) shows the fabric with large meshes
and the structure is atlas stitch. The warp-knitted structures
give the fabric certain tension strength, elasticity, durability
and different sizes of meshes. Studies show that the size of
Side view the aperture will influence the clinical results. The size of the
aperture increases and the softness of slings will increase. The
chance of infection will decrease. The role materials include
polypropylenemono filament (e.g. TVT®) and polypropylene
multifilament monofilament (e.g., IVS®). Both TVT® and IVS®
have bigger meshes.
Fig. 15. Ligament advance reinforcement system The use of metallic expandable tracheal stents is to provide a
Fig. 15. Ligament advance reinforcement system palliative relief for severe airway obstruction. The Ultraflex™
stent (Micro-invasive, Boston Scientific, and Watertown, MA,
3.2.4 Cardiac Support Device USA) is a kind of mesh knitted by a single strand of nitinol wire.
[34,35]
Nitinol is an alloy of 55% nickel and 45% titanium, and it
Cardiac Support Device (CSD) is a warp-knitted elastic mesh has thermal memory. The stent is compressed along a supple
bag, which is cut and sewn on the basis of the shape of the guide by a coiled thread. If the thread is pulled, the stent will
heart.[29,30] Atlas stitch is the basic structure and the material self-expand to its final diameter (Fig. 15a). The Ultraflex™ stent
is multi-filamentous yarn to provide high-strength and fatigue- may be in an uncovered form or covered by a sheath of silastic.
resistant characteristics, while maintaining flexibility.[31] The The covered one is often used to prevent growth of tumor tissue
fabric with warp-knitted atlas stitch is glossy and it is easy to (Fig. 15b). And according to the difference of genders, the stent
slide on the surface of heart to provide acute wall support. diameters for patients differ.[36]
(a) (b)
(b)
Fig. 17. Urethral suspension sling. (a) Tricot stitch; (b) Atlas stitch
(a) (b)
Fig. 17. Urethral suspension sling. (a) Tricot stitch; (b) Atlas stitch
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Artificial tracheal stent is always biodegradable and can Compared with braided fabrics, knitted scaffolds can be proven
be absorbed by human body. Artificial tracheal stent can to favor deposition of collagenous connective tissue matrix and
temporarily replace the removed tracheal and maintain the is crucial for tendon/ligament reconstruction.[37] Weft plain stitch
airway travel-ability for easy regeneration of the tracheal. is applied to a large extent in tendon scaffold. PLGA and PGA
is the usual material for tendon scaffold. PLGA is used to knit
Plain plating stitch can be used to knit artificial tracheal stent. plain stitch as the external sheath and PGA fibers keep straight
The plating yarn is polyglycolide lactide (PLGA) and the ground as the core. And warp-knitting technology can be applied in the
is polypropylene (PP). The fabric is knitted on small diameter field of tendon scaffold. Fig. 21 is the core-sheath structure of
weft-knitting machine and it is a tubular fabric. And before the tissue engineering tendon scaffold.
being implanted in human body, the tracheal stent needs to be
coated and sterilized. 3.2.10 Artificial chest wall
3.2.8 Periodontal guided tissue regeneration Artificial chest wall is used to a large extent in chest wall
reconstruction. The two warp-knitted fabrics − tricot stitch
Periodontal patch is a kind of microporous membrane for the based on rib and tricot stitch based on interlock – are chosen
treatment of periodontal disease and guides the regeneration for their good properties to resist ladder. The materials
of periodontal tissue. The basic structure is plain stitch knitted include poly-p-dioxanone (PDS). Fig. 22 and Fig. 23 show
on a single circular knitting machine. Biodegradable fibers, the loop structure diagram and graphic record of guide bar
PLGA and PGA, are chosen as the materials. And according lay-in thread movement of the tricot stitch based on rib and
to the requirements, different shapes of the patch can be sewn. interlock.
Fig. 18. Urethral suspension sling.[36] (a) Self-expand to the final diameter; (b) The covered one to prevent growth of tumor tissue
C/HA Sponge
C HA Spone
PU/C Coating
Fig. 20. Some types of periodontal patches. (a)Elliptic type; (b) Square type; (c) adjacent surface type; (d) Single tooth type;
(e) Encircling type
Fig. 20 Some types of periodontal patches. (a) Elliptic type; ( b) Square type; ( c) adjacent surface type; ( d) Single tooth type; (e) Encircling type
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(e) Encircling type
Filling
Integral reinforcement
Fig. 21. The core-sheath structure of the tissue engineering tendon scaffold
Fig. 21. The core-sheath structure of the tissue engineering tendon scaffold
Fig. 22. The loop structure diagram and graphic record of guide bar lay-in thread movement of tricot stitch based on rib
Fig. 23.The loop structure diagram and graphic record of guide bar lay-in thread movement of tricot stitch based on interlock
Weft yarn and warp yarn can be inlayed in rib stitch to form
multi-axial fabric. This kind of fabric is a multi-layered biaxial Fig. 24. The axial fabric applied in radiotherapy stent
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weft knitted fabric (MBWK Fabrics). It can be used in the structure. Fig. 27 shows the new three-dimensional heating
department of orthopedics splint, such as foot splint (Fig. 25). textiles.
Weft yarn and warp yarn can be glass fiber or some other high-
performance fibers and the yarn knitting rib stitch can be PET
or other chemical fibers. The fabric is often compounded with
photosensitive resin to form the orthopedics splints in the same
shapes as the injured part.
Fig. 26. The theoretical position of the heat conductor in the spacer of
the warp knitting structure
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cruciate ligament reconstruction: a meta-analysis. [32] Zullo, M.A., et al., One-Year Follow-up of Tension-free
Orthopedic Journal of China, 2016. 24(20): p. 1868-1875. Vaginal Tape (TVT) and Trans-obturator Suburethral Tape
[25] Li, B., Y. Wang, and C. Qiu, Efficacy of LARS artificial from Inside to Outside (TVT-O) for Surgical Treatment
ligament versus tibialis anterior allograft for posterior of Female Stress Urinary Incontinence: A Prospective
cruciate ligament reconstruction: a comparative study. Randomised Trial. European Urology, 2007. 51(5): p.
Orthopedic Journal of China, 2016. 24(18): p. 1650-1654. 1376-1384.
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[27] Dericks Jr, G., Ligament advanced reinforcement system [34] Madden, B.P., S. Datta, and N. Charokopos, Experience
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[28] Hamido, F., et al., The use of the LARS artificial ligament
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[29] Starling, R.C., et al., Sustained Benefits of the CorCap
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