WHO CLASSIFICATION OF TUMOURS OF THE VULVA

EPITHELIAL TUMOURS

 Squamous cell tumours and precursors

o Squamous intraepithelial lesions
 Low-grade squamous intraepithelial lesion
 High-grade squamous intraepithelial lesion
 Differentiated-type vulvar intraepithelial neoplasia
o Squamous cell carcinoma
 Keratinizing
 Non-keratinizing
 Basaloid
 Warty
 Verrucous
o Basal cell carcinoma
o Benign squamous lesions
 Condyloma acuminatum
 Vestibular papilloma
 Seborrheic keratosis
 keratoacanthoma
 Glandular tumours
o Paget disease
o Tumor arising from Bartholin and other specialized anogenital glands
 Bartholin gland carcinomas
 Adenocarcinoma
 Squamous cell carcinoma
 Adenosquamous carcinoma
 Adenoid cystic carcinoma
 Transitional cell carcinoma
 Adenocarcinoma of mammary gland type
 Adenocarcinoma of Skene gland origin
 Phyllodes tumour, malignant
o Adenocarcinomas of other types
 Adenocarcinoma of sweat gland type
 Adenocarcinoma of intestinal type
o Benign tumours and cysts
 Papillary hidradenoma
 Mixed tumour
 Fibroadenoma
 Adenoma
  Adenomyoma
 Bartholin gland cyst
 Nodular Bartholin gland hyperplasia
 Other vestibular gland cysts
 Other cysts
 Neuroendocrine tumours
o High-grade neuroendocrine carcinoma
 Small cell neuroendocrine carcinoma
 Large cell neuroendocrine carcinoma
o Merkel cell tumour

NEUROECTODERMAL TUMOURS

 Ewing sarcoma

SOFT TISSUE TUMOURS

 Benign tumours
o Lipoma
o Fibroepithelial stromal polyp
o Superficial angiomyxoma
o Superficial myofibroblastoma
o Cellular angiofibroma
o Angiomyofibroblastoma
o Aggressive angiomyxoma
o Leiomyoma
o Granular cell tumour
o Other benign tumours
 Malignant tumours
o Rhabdomyosarcoma
 Embryonal
 Alveolar
o Leiomyosarcoma
o Epithelioid sarcoma
o Alveolar soft part sarcoma
o Other sarcomas
 Liposarcoma
 Malignant peripheral nerve sheath tumour
 Kaposi sarcoma
 Fibrosarcoma
 Dermatofibrosarcoma protuberans
MELANOCYTIC TUMOURS

 Melanocytic naevi
o Congenital melanocytic naevus
o Acquired melanocytic naevus
o Blue naevus
o Atypical melanocytic naevus of genital type
o Dysplastic melanocytic naevus
 Malignant melanoma

GERM CELL TUMOURS

 Yolk sac tumour

LYMPHOID AND MYELOID TUMOURS

 Lymphomas
 Myeloid neoplasms

SECONDARY TUMOURS