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ANATOMY
(Human Anatomy Made Simple)
Dr Rajesh K Kaushal
PG-DIAMS ANATOMY 2
CONTENTS
PG-DIAMS ANATOMY 3
INTRODUCTION
1. Pars intermedia in pituitary develops from
a) Roof of stomodeum
b) Neural crest
c) Alar plate of diencephalon
d) Endoderm
Pituitary gland is ectodermal in origin and develops from Rathke’s pouch (a surface ectodermal
diverticulum of the primitive oral cavity-stomodeum). Surface ectoderm forms anterior lobe
(adenohypophysis), pars tuberalis, pars intermedia, whereas posterior pituitary
(neurohypophysis/pars nervosa) develops from neuroectoderm (neural plate ectoderm) of
hypothalamus diverticulum (infundibulum).
Pituitary gland is present at the floor of middle cranial fossa in the sella turcica (Turkish saddle) in
sphenoid bone.
Cranio-pharyngioma tumour (CPT) is a rare, suprasellar neoplasm, developing from Rathke's pouch
epithelium. Patient may present with bitemporal inferior quadrantanopia leading to bitemporal
hemianopia, as the tumor may compress the optic chiasm.
Tongue develops from all the three germ layers, connective tissue from pharyngeal arch mesoderm,
muscles from occipital somites and epithelium from ectoderm and endoderm. Sulcus terminalis lies at
the endoderm and ectoderm junction. Tonsillar epithelium develops from endoderm.
PG-DIAMS ANATOMY 4
Gametogenesis
Gametogenesis is formation of gamete from primordial germ cells and involves cell division mitosis
and meiosis.
Primordial germ cells (PGCs) are derived from the epiblast, they migrate to the endodermal wall of
the yolk sac (fourth week) and then reach the indeterminate gonad by the end of the fifth week, to
differentiate into gametes (gametogenesis). Aberrant migration may lead to germ cell tumours (for
e.g., teratoma).
1. Abnormal persistence of which of the following cells from primitive streak result in
sacrococcygeal teratoma
a) Primordial germ cells
b) Endodermal cells
c) Mesodermal cells
d) Ectodermal cells
Teratomas may arise from PGCs (or from epiblast cells), which are pluripotent cells. Therefore, within
teratomas are present derivatives of all three germ layers and may include skin, bone, teeth, gut
tissue.
PG-DIAMS ANATOMY 5
2. After entering first meiotic division, primary oocyte remains arrested in which stage
a) Diplotene
b) Pacyhtene
c) Metaphase
d) Telophase
Oogenesis
Meiosis consists of two cell divisions (meiosis I and meiosis II) and results in the formation of gametes
containing 23 chromosomes and 1N amount of DNA (1n, 1N), where n is the number of chromosomes
and N is the unit (amount) of DNA. Meiosis I is a reduction division and reduces the chromosome
number to half in gamete.
During oogenesis, primordial germ cells differentiate into oogonia (46,2N), which enter meiosis I and
undergo DNA replication to form primary oocytes (46,4N). All primary oocytes are formed by the fifth
month of fetal life (about 7 million), and remain dormant in prophase (diplotene/dictyotene stage) of
meiosis I until the beginning of LH surge (puberty).
Primary oocyte completes meiosis I to form a secondary oocyte (23,2N) and a first polar body (which
later degenerates). The secondary oocyte enters meiosis II, remains arrested in metaphase of
meiosis II until fertilization occurs.
At fertilization, the secondary oocyte completes meiosis II to form a mature oocyte (23,1N) and a
second polar body.
3. Which cell undergoes fertilization
a) Primary oocyte in prophase arrest
b) Primary oocyte in metaphase arrest
c) Secondary oocyte in prophase arrest
d) Secondary oocyte in metaphase arrest
PG-DIAMS ANATOMY 6
4. Secondary oocyte is
a) Haploid (n) and N
b) Haploid (n) and 2N
c) Diploid (2n) and N
d) Diploid (2n) and 2N
Fertilization occurs within 24 hours of ovulation, and there is a narrow opportunity window for
conception (2 days preceding or on the day of ovulation).
Infertility Clinic
Gastrulation
Placenta: The fetal portion of the placenta forms from the trophoblast. Syncytiotrophoblast cells are in
direct contact with maternal tissue, whereas the embryo proper is separated from the cytotrophoblast by
extraembryonic mesoderm (together, the chorion).
Chorion: Extra-embryonic connective tissue + cytotrophoblast + syncytiotrophoblast
The presumptive umbilical blood vessels form in the wall of the allantois, an endodermal out pocketing
of the urogenital sinus. The amnionic membrane develops from epiblast and is continuous with
embryonic ectoderm. The lining of the yolk sac develops from hypoblast and is continuous with
embryonic endoderm. The yolk sac gives rise to the first blood islands that will form the vitelline vessels.
PG-DIAMS ANATOMY 11
DiGeorge syndrome : Presents with chromosome 22q11 deletion. Neural crest cell migration is
affected and patients lack mature T cells (due to absence of thymus). There is defective development
of pharyngeal pouch three and four. Most common cause of death is cardiovascular defects, though
severe bacterial infections, hypocalcaemic tetany may also lead to grave consequences.
Presentation: Positive Chvostek sign (and Trousseau sign); recurrent infections (viral, fungal, and
protozoal); characteristic facies (micrognathia, broad nasal bridge, long face, narrow palpebral fissures,
, asymmetric crying face)
Diagnostics: Hypocalcemia, lymphopenia, absent thymic silhouette on neonatal imaging
Treatment: Patients is supported by calcium supplementation and prophylactic antibiotics. Surgical
correction of cardiac and vascular defects may be carried out.
Mesoderm derivatives
PG-DIAMS ANATOMY 13
17. All of the following muscles are derivatives of para-axial mesoderm EXCEPT
a) Masseter
b) Diaphragm
c) Biceps femoris
d) Detrusor
18. Muscle derived from visceral splanchnic lateral plate mesoderm is
a) Myo-epitheliocytes of skin glands
b) Iris muscles
c) Smooth muscles of gut tube
d) Detrusor
Vertebra develops from the sclerotome (somite), which covers nucleus pulposus and the spinal cord.
Non fusion of sclerotome halves on the posterior aspect results in spina bifida.
PG-DIAMS ANATOMY 14
Biceps and Masseter are skeletal muscles developing from para-axial mesoderm. Humerus
(appendicular skeleton) develops from dorsal somatic portion of lateral p;late mesoderm. Adrenal
cortex (and kidney) develops from intermediate mesoderm. Adrenal medulla (contains sympathetic
neurons) is derived from neural crest cells.
The muscles and bones of the trunk are derived from the somites. Each somite forms two distinct
zones: a sclerotome and a dermomyotome. The former gives rise to the bones of the axial skeleton.
The latter gives rise to the dermatome and myotome, in which dermatome forms the dermis of the
back skin of the trunk and neck and the myotome forms the muscles of the trunk, limbs and tongue.
The dermis and bones of the limbs develop from lateral plate mesoderm. The bones of the head and
neck arise from neural crest cells, as does most of the dermis of the head, whereas the pharyngeal
arch muscles like masticatory, facial, laryngeal muscles etc. arise from unsegmented paraxial
mesoderm in head.
The smooth muscles of the arterial tree are from various embryological origins.. Upper-body arterial
smooth-muscle cells (like aortic arch) derive from the neural crest, whereas lower-body arteries
derive smooth-muscle cells from neighboring mesodermal structures (for e.g., smooth muscle of
dorsal aorta arise from para-axial mesoderm). Derivatives of the proepicardial organ, which gives rise
to the epicardial layer of the heart, contribute to the vascular smooth-muscle cells of the coronary
arteries. Recent evidence suggests that bone marrow may give rise to both vascular endothelial cells
and smooth-muscle cells, particularly under conditions of injury repair or vascular lesion formation.
Endoderm derivatives
20. Vaginal epithelium is derived from
a) Endoderm of genital ridge
b) Endoderm of urogenital sinus
c) Mesoderm of genital ridge
d) Mesoderm of urogenital sinus
The most common form of Tracheo-Oesophageal Fistula (TOF), the esophagus ends in a blind
pouch (esophageal atresia) and air enters the stomach (gastric bubble on radiograph). Patient may
present with gastric acid aspiration pneumonitis.
PG-DIAMS ANATOMY 15
23. How many oocytes are present at fifth month of intrauterine life
a) 1 million
b) 5 million
c) 7 million
d) 400
24. At the end of 5th week of gestation, how many number of somites can be seen
a) 24
b) 26
c) 38
d) 44
25. Which muscle does NOT develop from hypaxial mesoderm
a) Erector spinae
b) Quadratus lumborum
c) Infrahyoid muscles
d) Scalenus muscles
PG-DIAMS ANATOMY 16
Additional Questions
26. Spermatogenesis is completed in
a) 60 days
b) 64 days
c) 70 days
d) 74 days
Ans. d) 74 days >b) 64 days.
Explanation: Spermatogenesis takes 74 days to complete. Earlier editions of standard textbooks used to
mention it as 64 days (2 months).
29. All of the following statements are true concerning the early embryological development
EXCEPT
a) Zona pellucida is a glycoprotein membrane preventing implantation
b) Blastocyst attaches to endometrium on day 6
c) Primordial germ cells are derivative of epiblast
d) The first germ layer to form is ectoderm
Ans. d) The first germ layer to form is ectoderm.
Explanation: Endoderm is the first germ layer to develop from the epiblast, followed by mesoderm and
then ectoderm.
30. Trophoblast differentiates into cyto and syncytio-trophoblast at day
a) 4
b) 6
c) 8
d) 10
Ans. b) 6.
Explanation: Trophoblast in the outer cell mass differentiate into cyto-trophoblast and syncytio-trophoblast
at the 6th day of development and form placenta. Syncytio-trophoblast attaches the conceptus to the
endometrium wall and secrete HCG (Human Chorionic Gonadotropin).
PG-DIAMS ANATOMY 17
Epithelium
Larynx is lined by respiratory epithelium (pseudo-stratified ciliated columnar epithelium with goblet
cells) except at the vocal cords, which are lined by stratified squamous epithelium.
Cornea has five layers, in which the anterior most is surface (stratified squamous) epithelium.
The auricle (pinna) is made up of elastic cartilage and is covered by skin (stratified squamous
epithelium). External auditory canal is covered by skin with sebaceous glands and ceruminous
glands (modified apocrine sweat glands that produce wax).Tympanic membrane is lined by skin
(stratified squamous epithelium) on its external surface and simple cuboidal epithelium on its inner
surface.
Nasal vestibule is lined by skin with appendages like hair follicles and associated glands.
Oral cavity has non-keratinized stratified squamous epithelium. Para-keratinization: persistence of
the nuclei of the keratinocytes into the stratum corneum; this is normal only in the epithelium of true
mucous membranes of the mouth and vagina.
PG-DIAMS ANATOMY 22
Wet surface openings like eyes, oral cavity, urethra, vagina, anal canal should not have keratin
(dryness).
Barrett esophagus: Peptic ulcer of the lower esophagus (often with stricture). Biopsy shows replacement
(metaplasia) of normal stratified squamous epithelium by columnar (non - absorptive) epithelium and
goblet cells. Sometimes functional mucous cells, parietal cells, or chief cells may also be present. It is a
pre-malignant leading to esophageal adenocarcinoma occasionally.
PG-DIAMS ANATOMY 24
a) Anal canal
b) Rectum
c) Cervix
d) Oesophagus
Squamo-columnar junction is present at the endocervix and ectocervix junction. Uterus is lined by
ciliated columnar epithelium and vagina has stratified squamous epithelium.
Gastric glands
7. All are correct about stomach EXCEPT
a) Pylorus has more acid secreting cells
b) Lots of mucous secreting cells in pylorus
c) Chief cells secrete pepsinogen
d) Parietal cells secrete intrinsic factor
PG-DIAMS ANATOMY 25
Intestinal Epithelium
8. Paneth cells are most distinguished by
a) High zinc content
b) Numerous lysozyme granules
c) Rich rough endoplasmic reticulum
d) Foamy appearance
Paneth cells is distinguished by the apical eosinophilia in H&E staining. The apical region has large
number of lysozymes, which takes eosin, making the paneth cell appear dark pink at the apex. Paneth
cells are rich in zinc and have large amount of endoplasmic reticulum as well, but are not the
answers of first preference. Mucus in the Goblet cells give the foamy appearance and not a feature of
Paneth cells.
PG-DIAMS ANATOMY 26
At least six types of cells are found in intestinal mucosal epithelium. 1. Columnar cell (Enterocytes):
For absorption 2. Goblet cell: Mucus production, 3. Paneth cell: Maintain intestinal flora by secreting
antimicrobial substances. 4. Enteroendocrine cell: Secrete paracrine and endocrine hormones 5. M
cells (microfold cells), modified enterocytes that cover enlarged lymphatic nodules in the lamina
propria. 6. Stem cell: for repair of epithelium.
Paneth cells are columnar epithelial cells migrating towards the base of the intestinal glands,
occurring in the fundus of the crypts of Lieberkuhn; they contain large granules that secrete
antimicrobial substances such as defensins (like TNF - ).
Connective Tissue
Collagen fibres
Type Distribution
I Bone, Fibro-cartilage, skin
II Cartilage (hyaline & elastic)
III Lymphoid tissue, blood vessels (e.g., RA)
IV Basement membrane
Lymphoid Tissue
9. GALT (Gut Associated Lymphoid tissue) is present in
a) Submucosa
b) Lamina propria
c) Muscularis mucosa
d) Adventitia/Serosa
GALT is present in the lamina propria (mucosa) of the body tubes, though it may also be found in the
submucosa occasionally (for e.g., vermiform appendix). In this case the smooth muscle layer of
muscularis mucosa is interrupted at places.
PG-DIAMS ANATOMY 27
Primary lymphoid organs: 1. Bone marrow – Has the stem cells that develop into B lymphocytes,
which form plasma cells to secrete antibodies (humoral immunity). Most other leukocytes migrate to
peripheral sites to fully mature. 2. Thymus – Receive stem cells from bone marrow and train them as T-
lymphocyte (cell mediated immunity).
Secondary lymphoid organs: Tonsils, lymph nodes, spleen, MALT etc. Lymphoid organs have type III
collagen fibres.
Mucosa-associated lymphoid tissue (MALT) is unencapsulated lymphoid tissue that lines the
digestive tract (GALT), respiratory tract (BALT), and genitourinary tract. Peyer patches are found in the
lamina propria of the ileum and are separated from the intestinal lumen by a layer of flattened epithelial
cells known as microfold cells (M cells). M cells transcytose antigens and present to the underlying
Peyer patches, where APCs phagocytose the antigens and present them to resident T cells and B cells.
Skin
PG-DIAMS ANATOMY 28
The epidermis of thick skin consists of five layers of cells (keratinocytes): stratum corneum
(characterized by dead and dying cells with compacted keratin), stratum lucidum (a translucent layer
not obvious in thin skin), stratum granulosum (characterized by kerato-hyalin granules), stratum
spinosum (characterized by tonofibrils and associated desmosomes) and stratum basale (proliferative
layer. The epidermis regenerates approximately every 30 days, is carried out by the mitotic activity of
stem cells at the basal layer.
Non-keratinocyte epidermal cells include melanocytes (derived from neural crest), Langerhans cells
(antigen-presenting cells derived from monocytes), and Merkel cells (sensory mechanoreceptors;
derived from neural crest).
Langerhans cells are dendritic cells derived from monocyte-phagocyte series in the bone marrow; lack
tonofilaments, desmosomes, and melanosomes. These cells are identified by the presence of tennis
racket–shaped organelles known as Birbeck granules. They are found principally in the stratum
spinosum of the epidermis, but also in lymph nodes, spleen, and thymus. Their surface markers are
characteristic of macrophages, and are antigen-presenting cells involved in contact allergic responses
and other cell-mediated immune reactions in the skin (delayed hypersensitivity).
Langerhans cell histiocytosis is a disease characterized by the excessive proliferation of Langerhans
cells, which can manifest as skin or bone lesions.
Sensory Receptors
Golgi tendon organs are encapsulated mechanoreceptors sensitive to stretch and tension in tendons
and carry proprioceptive information.
Muscle spindle receptors are also encapsulated and carry proprioception. They have intrafusal
muscle fibers called flower spray endings and annulospiral endings that sense differences in muscle
length and tension.
Cell Junctions
10. 20 nm of intercellular gap is found in the following cell junction
a) Zona occludens
b) Zona adherence
c) Macula adherence
d) Gap junctions
Pemphigus vulgaris the most common and severe form of pemphigus, seen usually in persons 40
to 60 years old, characterized by chronic, flaccid, easily ruptured blisters on the skin and mucous
membranes. It begins focally but then becomes generalized, leaving large, weeping, denuded
surfaces that partially crust over but do not heal and enlarge by confluence. Autoantibodies are
detected against the cadherins of desmosomes. Nikolsky sign becomes positive.
Bullous pemphigoid is a usually mild, self-limited, sub-epidermal blistering skin disease,
sometimes with oral involvement, predominantly affecting the elderly; characteristics include large,
tense bullae that rupture to leave denuded areas and have a tendency to heal spontaneously, and
cleft formation and deposition of complement, usually with the IgG class of immunoglobulins, at the
dermo-epidermal junction. Autoantibodies are detected against the hemi-desmosomes.
PG-DIAMS ANATOMY 30
11. In the electron micrograph below, the structure labelled ‘D’ primarily does which of the
following
Osteoblasts synthesize type I collagen and bone matrix proteins to form an unmineralized osteoid.
Calcium and phosphate are deposited on the cartilaginous matrix to form mineralized bone. Blood
supply within the haversian canals supply osteoblasts. Later osteoblasts become surrounded by
bone matrix to become osteocytes.
Osteocytes are present in the space called lacuna and communicate with other osteocytes via
cytoplasmic extensions called canaliculi . They are not directly involved in bone resorption but under
the influence of parathyroid hormone (PTH) they stimulate osteoclastic bone resorption, which
allows Calcium to be transferred rapidly into the blood.
Osteoclasts are multinucleated cells (formed from monocytes), contain acid phosphatase and
under influence of PTH cause bone resorption.
Bone formation occurs in two ways. During endochondral ossification, a cartilage model first forms
and is eventually replaced with bone, except at epiphyseal plates and articular cartilages. This type of
ossification underlie formation of the axial (vertebral column and ribs) and appendicular (limb)
skeletons, with the exception of part of the clavicles.
During intramembranous ossification, bone forms directly from mesenchymal cells without the prior
formation of cartilage. This type of ossification underlies formation of the majority of bones of the face
and skull.
Primary ossification centre appears in the developing bone (at 6 – 12 weeks of intra-uterine life) and
forms diaphysis. Secondary ossification centres appear (usually after birth) at the ends of long
bones and develop into epiphysis.
Nutrient artery is directed away from the growing ends (towards the elbow I go, from the knee I flee).
For e.g., Nutrient foramen in tibia is immediately below the popliteal line and directed obliquely
downward, away from knee joint. It also suggests that the ends of the bones at knee joint and elbow
joints are growing ends.
Joints
13. Inferior tibio-fibular joint is
a) Synchondrosis
b) Syndesmosis
c) Symphysis
d) Schindylesis
PG-DIAMS ANATOMY 32
a) B
b) C
c) D
d) E
The submucosa consists of a layer of fibroelastic connective tissue containing blood vessels and
nerves. It is the strongest component of the oesophagus and intestinal wall and therefore must be
included in anastomotic sutures.
16. Intestinal epithelium has which cell type (AIIMS)
a) T lymphocytes
b) B lymphocytes
c) Macrophages
d) Neutrophils
17. All of the following are the components of the white pulp of spleen EXCEPT
a) Periarteriolar lymphoid sheath
b) B cells
c) Antigen presenting cells
d) Vascular sinus
The spleen is composed of white pulp (25%) having large number of white blood cells arranged in
diffuse and nodular lymphoid tissue for immune function. Red pulp (75%) has large number of red
blood cells and consists of venous sinusoids and splenic cords.
White pulp has lymphoid follicles with eccentric arterioles surrounded by T lymphocytes (PALS – Peri
Arteriolar Lymphatic Sheath). B lymphocytes are distributed at the germinal centres of lymphoid
follicles.
PG-DIAMS ANATOMY 34
Bronchioles have a diameter smaller than 1 mm and lack cartilage and glands within their walls.
Goblet cells (and cilia) decrease in number and almost negligible at the levels of bronchioles (small
lumen). Hyaline cartilage also is almost non-existent at the levels of bronchioles. Epithelium gradually
changes from pseudo -stratified columnar to simple columnar to cuboidal to squamous.
Alveolus is lined by type-I pneumocyte (simple squamous epithelium) for respiratory gas exchange.
Type- II pneumocyte is a cuboidal cell for surfactant secretion.
Bronchial arteries (branches of descending thoracic aorta) supply till the level of respiratory
bronchiole. They perfuse the proximal air conducting pathways including tertiary and terminal
bronchioles and reach till the beginning of respiratory unit. Pulmonary arteries alone vascularize the
further distal pathways, including alveolar ducts and the alveoli.
20. Dense and regular arrangement of collagen fibres is seen in all EXCEPT (AIIMS)
a) Tendon
b) Ligament
c) Aponeurosis
d) Periosteum
Dense connective tissue contains more fibers and fewer cells and is classified by the orientation of
its fiber bundles into two types:
1. Dense and irregular connective tissue (most common), which contains fiber bundles that have no
definite orientation. For e.g., dermis and organ capsules.
2. Dense, regular connective tissue, which contains fiber bundles are arranged in a uniform parallel
fashion with few fibroblasts. E.g., Tendons, ligaments.
Additional Questions
22. Thyroid follicles are lined by (PGIC)
a) Simple squamous
b) Simple cuboidal
c) Stratified cuboidal
d) Simple columnar
e) Stratified columnar
Ans. a) Simple squamous; b) Simple cuboidal; d) Simple columnar.
Explanation: Thyroid follicles are lined by simple cuboidal epithelium. The epithelium changes to simple
columnar in hyper-secretion (amount of endoplasmic reticulum increases), and to simple squamous
epithelium in hypo-secretion (resting follicle).
PG-DIAMS ANATOMY 36
24. The ducts of all the following glands consist of stratified cuboidal epithelium EXCEPT
a) Sweat glands
b) Sebaceous glands
c) Salivary glands
d) Pancreas
Ans. b) Sebaceous glands.
Explanation: The ducts of all exocrine glands are generally lined by stratified cuboidal/columnar
epithelium, with few exceptions (sebaceous duct) which carries the same lining as that of skin (stratified
squamous epithelium).
25. Chief cells are found at which part of the gastric gland
a) Neck
b) Isthmus
c) Body
d) Fundus
Ans. d) Fundus.
Explanation: Chief cells are chiefly found at fundus of stomach (gross anatomy) and fundus of gastric
gland (histology). Stem cells are predominantly located at the isthmus.
28. Which of the following is lined by an epithelium containing ciliated cells and Clara cells
a) Nasopharynx
b) Trachea
c) Respiratory bronchiole
d) Intrapulmonary bronchi
Ans. c) Respiratory bronchiole.
PG-DIAMS ANATOMY 37
Explanation: Clara (club) cells are predominantly present in the terminal bronchiole and also in respiratory
bronchiole. They function as stem cells for the repair of respiratory epithelium. They are also involved in de-
toxification of the inhaled air. They also secrete surfactant lipoproteins.
29. All of the following are categorized as secondary lymphoid organs EXCEPT
a) Lymph nodes
b) Spleen
c) Thymus
d) Subepithelial collections of lymphocytes
e) Bone marrow
30. Following are given the collagen types and the sites of location. Choose the INCORRECT pair
a) Skin : Type – I
b) Lens Capsule : Type – I
c) Blood vessel : Type – III
d) Spleen : Type – III
e) Hyaline cartilage : Type – I
Ans. b) Lens capsule; e) Hyaline cartilage.
Explanation: Generally capsules have type – I collagen fibres; lens capsule/ filtration membrane have type
IV collagen fibres. Hyaline cartilage has type II collagen fibres.
Collagen fibres
Type Distribution
I Bone, Fibro-cartilage, skin, capsule(joint, organ)
II Cartilage (hyaline & elastic)
III Lymphoid tissue, blood vessels
IV Basement membrane, lens capsule
33. Which of the following functions in metabolic coupling between adjacent cells
a) Tight junction
b) Desmosome
c) Gap junction
d) Zonula adherens
PG-DIAMS ANATOMY 38
34. In pemphigus vulgaris autoantibodies are formed against which cell adhesion molecule
a) Selectin
b) Cadherin
c) Integrin
d) IgSF
Ans. b) Cadherin.
Explanation: Autoantibodies are directed against the cadherins (of desmosomes) in pemphigus vulgaris,
which leads to intercellular separation (Nikolsky sign present).
Pressure epiphysis are involved in weight transmission (and are intracapsular) for e.g., head of humerus
& femur and condyles of humerus, femur, tibia etc.
Coracoid process in scapula is an example of atavistic epiphysis.
Deltoid tuberosity is not an epiphysis (it is present on the shaft/diaphysis).
Section 3. NeuroAnatomy
Embryology
Neurulation begins in the third week of development. As the primitive streak regresses caudally, the
notochord develops in the axial line of the embryo (between the buccopharyngeal membrane and
cloacal membrane).
Notochord induces the overlying ectoderm to form the neural plate. By the end of the third week, the
lateral margins of the neural plate thicken and become elevated to form the neural folds with the
neural groove located centrally between the two folds. The neural folds then grow over the midline
and begin to fuse to form the neural tube. Closure of the neural tube begins in the cervical region
and continues cranially and caudally (The recent literature mentions multiple levels of fusion).
The anterior (cranial) neuropore closes earlier than the posterior (caudal) neuropore. Failure of closure
of the neuropores results in open neural tube defects (anencephaly and rchischisis) and present with
elevated levels of alpha-fetoprotein levels (and acetylcholine-esterase).
Neural crest cells are the fourth germ layer cells, which appear at the margins of the neural folds
during closure of the neural tube. (Earlier neural crest cells were considered to be derived from
nneuro-ectoderm).
Neural crest cells contribute to the peripheral nervous system and most of the ganglia are derived from
these cells.
1. Neural tube begin to close from which region
a) Cranial
b) Cervical
c) Thoracic
d) Lumbar
PG-DIAMS ANATOMY 41
The first CSF (cerebro spinal fluid) is formed of amniotic fluid, and is later secreted by the choroid
(capillary) plexus in the lateral ventricles (chiefly) and partly in third and fourth ventricles. It escapes
the ventricular space at the roof of fourth ventricles at three foramina (midline Magendie and two
lateral Luschka) into the subarachnoid space. (Sub – under).
CSF circulating in the sub-arachnoid space is absorbed into the dural venous sinus (for e.g., superior
sagittal sinus) via arachnoid granulations. Dural venous sinus is the intradural space (between two
layers of duramater), contains venous blood from several tributaries including veins of brain.
Non-communicating hydrocephalus may result from obstruction within the ventricles (e.g., congenital
aqueductal stenosis). Communicating hydrocephalus results from blockage within the subarachnoid
space (e.g., adhesions after tuberculous meningitis).
PG-DIAMS ANATOMY 42
PG-DIAMS ANATOMY 43
Hippocampus is concerened with recent memory traces and is related to the inferior (temporal) horn
of lateral ventricle.
PG-DIAMS ANATOMY 44
Choroid plexus is a capillary plexus projecting into the ventricles to secrete CSF (ultrafiltrate of blood).
The anterior part of the floor of the third ventricle is formed mainly by hypothalamic structures.
Immediately behind the optic chiasma lies the thin infundibular recess, which extends into the
pituitary stalk. Behind this recess, the tuber cinereum and the mammillary bodies form the floor of
the ventricle.
Pineal gland is at the posterior wall of third ventricle.
Thalamus and hypothalamus are at the lateral wall of third ventricle.
Lamina terminalis is at the anterior wall of third ventricle.
Abducent(6) , vestibular(8), vagus(10) , hypoglossal(12) nuclei are at the floor of 4th ventricle.
5. Visceral efferent column in the lateral horns of spinal cord arises from which plate of the neural
tube
a) Alar
b) Basal
c) Roof
d) Floor
Mantle zone of the spinal cord (and brain stem) gets organized into a pair of anterior (basal) plates
and posterior (alar) plates. Laterally, sulcus limitans is present between the two plates; dorsally
and ventrally, they are connected by nonneurogenic structures(roof plate and floor plate). Sensory/
association neurons form in the dorsal plates, the somatic motor column and the visceral motor
column form in the ventral plates.
Special Somatic Afferent (SSA) fibers convey special sensory impulses of smell, vision, hearing &
balance to the CNS.
Special Visceral Afferent (SVA) fibers transmit taste sensations to the CNS.
General Somatic Afferent (GSA) fibers transmit general sensations like touch, pain, temperature,
proprioception from the body to the CNS.
General Visceral Afferent (GVA) fibers carry sensory impulses from visceral organs to the CNS. For
e.g., carotid sinus pressure sensation.
General Visceral Efferent (GVE) fibers transmit motor impulses to smooth muscle, cardiac muscle,
and glandular tissues (Autonomic Nervous system).
General Somatic Efferent (GSE) fibers conduct motor impulses to the skeletal (somatic) muscles of
the body.
Special Visceral Efferent (SVE) fibers convey motor impulses to the muscles of the head and neck,
which develop from pharyngeal arches such as muscles of mastication, muscles of facial
expression, and muscles of palate, pharynx and larynx (speech & swallowing).
7. All of the following nuclei belong to GSE (General Somatic Efferent) EXCEPT
a) Occulomotor
b) Trochlear
c) Trigeminal
d) Abducent
Alar plates give rise to the superior and inferior colliculi (rounded protuberances on the dorsal
surface of the midbrain).The superior colliculi control ocular reflexes; the inferior colliculi serve as
relays in the auditory pathway.
PG-DIAMS ANATOMY 47
Basic NeuroAnatomy
Cerebrum
8. While doing surgery for meningioma on cerebral hemisphere, there occurred injury to left
paracentral lobule, it will lead to paresis of
a) Left face
b) Right neck and scapular region
c) Right leg and perineum
d) Right shoulder and trunk
PG-DIAMS ANATOMY 48
PG-DIAMS ANATOMY 49
Para-central lobule: Paracentral lobule is on the medial surface of the hemisphere and is the
continuation of the precentral and postcentral gyri. The paracentral lobule is supplied blood by the
anterior cerebral artery. The paracentral lobule controls motor and sensory innervations of the
contralateral lower extremity. It is also responsible for control of defectation and urination.
9. All of the following pairs for Brodmann area are correct EXCEPT
a) Superior temporal gyrus: Auditory cortex (41,42)
b) Superior temporal gyrus: Wernicke’s sensory speech area (22)
c) Inferior frontal gyrus: Broca’s motor speech area (44)
d) Superior frontal gyrus: Frontal eye field (8)
Frontal eye field (8) is present in the middle frontal gyrus. Frontal eye field is the center for
contralateral horizontal gaze. A lesion results in an inability to make voluntary eye movements
toward the contralateral side. Since the activity of the intact frontal eye field in the opposite cortex is
unopposed in such a lesion, the result is conjugate slow deviation of the eyes toward the side of the
lesion.
Auditory cortex is located at the anterior part of the superior temporal gyrus (transverse temporal
gyri of Heschl). Wernicke’s sensory speech area is present at the posterior part of the superior
temporal gyrus. Broca’s motor speech area is present on the inferior frontal gyrus.
11. Which of the following fibres DON’T pass through the posterior limb of internal capsule
a) Sublentiform
b) Retrolentiform
c) Corticonuclear
d) Dorsal column
Diencephalon includes thalamus and all the related thalami including epithalamus, hypothalamus,
metathalamus, subthalamus etc. Both medial geniculate body and lateral geniculate body are part of
metathalamus.
PG-DIAMS ANATOMY 51
Trochlear nerve arises from lower midbrain and Abducent arises from pons.
PG-DIAMS ANATOMY 52
The NTS (Nucleus Tractus Solitarius) in the medulla receives taste sensation from three nerves: 1.
The anterior two-thirds of the tongue via the chorda tympani nerve of the facial nerve (CN VII) 2.
The posterior third of the tongue via the glossopharyngeal nerve (CN IX) 3. The posteriormost
tongue (and epiglottic region of the pharynx) via the vagus nerve (CN X).
Neurons carrying taste sensations ascend in the ventral tegmental tract to the VPM nucleus of the
thalamus, which further project the fibres to fibers to the parietal lobe.
13. All of the following pairs regarding neural columns and associated nuclei are correct EXCEPT
a) Hypoglossal nucleus: GSE
b) Nucleus ambigus: SVE
c) Dorsal nucleus of vagus: GVA
d) Nucleus tractus solitarius: SVA
Nucleus tractus solitarius has both SVA and GVA neural columns. Taste sensations reach the
upper part of the nucleus, whereas, other sensations like carotid sinus pressure sensations reach the
lower part of the nucleus.
*SVE: Special(S) muscles (E) which develop around the pharynx viscera (V) – pharyngeal arch muscles:
Arch – I (Muscles of mastication, 5th nerve)
Arch – II (Muscles of facial expression, 7th nerve)
Arch – III, IV and VI (Palate, pharynx and larynx muscles), Nucleus Ambiguus (9, 10, 11 nerves).
* GVE & GVA are under ANS (Autonomic nervous system).
PG-DIAMS ANATOMY 53
Cerebellum
Cerebellum is concerned with coordination of voluntary motor activity, controls posture, euillibrium and
muscle tone, and is involved learning of repeated motor functions, Cerebellar lesion leads to abnormal
gait, disturbed balance, and in-coordination of voluntary motor activity (no paralysis or inability to start
or stop movement).
Mossy fibres (and climbing fibres) are the afferent fibres reaching the cerebellum via the cerebellar
peduncles. These are excitatory in nature and project directly (or indirectly via granule cells) to the
Purkinje cells of the cerebellar cortex.
The axons of the Purkinje cells are inhibitory (GABA – ergic) and are the only efferent (outflow) from
the cerebellar cortex. They project to and inhibit the deep cerebellar nuclei (dentate, interposed, and
fastigii) in the medulla.
From the deep nuclei, efferents project through the superior cerebellar peduncle to the contralateral
ventral lateral (and ventral anterior) nuclei of the thalamus, to reach the contralateral cerebrum
(precentral gyrus). The upper motor neurons of the cerebrum thence influence the contralateral lower
motor neurons of the spinal cord via corticospinal tract.
14. Function of spinocerebellar tract
a) Equilibrium
b) Coordinates movement
c) Learning induced by vestibular reflexes
d) Planning and Programming
PG-DIAMS ANATOMY 54
Questions: NeuroAnatomy - I
16. A new-born has multiple congenital defects due to dysgenesis of the neural crest. Which of
the following cells is most likely to be spared
a) Dorsal root ganglion cells
b) Geniculate ganglion cells
c) Melanocytes
d) Motor neurons
17. Brainstem nucleus NOT derived from alar plate
a) Dentate
b) Inferior olivary
c) Hypoglossal
d) Substantia nigra
18. Which of the following cranial nerve is associated with special somatic afferent nuclei
a) V
b) VI
c) VII
d) VIII
PG-DIAMS ANATOMY 55
19. Which of the following reflexes test the integrity of nucleus ambiguus
a) Jaw jerk
b) Stapedial reflex
c) Gag reflex
d) Corneal reflex
PG-DIAMS ANATOMY 56
Gag reflex: Contraction of the constrictor muscle of the pharynx elicited by touching the back of the
pharynx.
Stapedial reflex: Contraction of the stapedius muscle in response to loud/intense sound.
Corneal reflex: Irritation of the cornea results in reflex closure of the lids.
20. Cells present in cerebellar cortex are all EXCEPT
a) Bipolar
b) Purkinje
c) Golgi
d) Granule
21. Efferents in superior cerebellar peduncle arise mostly from
a) Purkinje cells
b) Stellate neurons
c) Deep nuclei
d) Grade III fibres
22. Efferents from cerebellum arise from
a) Purkinje cells
b) Stellate neurons
c) Deep nuclei
d) Grade III fibres
Efferents from the cerebellar cortex arise from the purkinje cells.
Additional Questions
23. True about cerebrospinal fluid is (PGIC)
a) Produced by choroid plexus
b) Travels from sub-arachnoid space to the fourth ventricle
c) Absorbed by arachnoid villi
d) Drains into the dural venous sinuses
e) Aqueductal stenosis dilates 4th ventricle
Ans. a) Produced by chroid plexus; c) Absorbed by arachnoid villi; d) drains into dural venous
sinuses.
Explanation: CSF moves out of fourth ventricle into the sub-arachnoid space. Aqueductal stenosis dilates
the proximal ventricles 1 ,2 and 3 (and not 4th).
central canal eventually. CSF escapes the fourth ventricle into the sub-arachnoid space via three foramina:
One midline Magendie and two lateral Luschka. CSF absorption from the sub-arachnoid space occurs by
the arachnoid villi (granulations) projecting into the dural venous sinuses (for e.g., superior sagittal sinus).
Ans. a) Thalamus.
Explanation: Basal ganglia is involved in programming and planning of the voluntary motor activity and is
constituted by numerous nuclei. It has connections with thalamus (but thalamus is not an integral
component), whereas subthalamus is definitely considered as the functional component of basal ganglia.
34. How many nuclei does the trigeminal nerve have in the CNS
a) Three
b) Four
c) Five
d) Six
Ans. b) Four.
Explanation: Trigeminal nerve has one motor and three sensory nuclei. The motor nucleus is located in
pons and send the motor fibres by mandibular nerve (branch of trigeminal) to control the eight muscles
developing in the first pharyngeal arch, for e.g., muscles of mastication. The main sensory nucleus is
present in the pons, whereas midbrain has the mesencephalic sensory nucleus of trigeminal (for
proprioception) and the spinal sensory nucleus of trigeminal has neurone bodies extending into the spinal
cord (carry pain & temperature).
35. Proprioceptive impulses for masseter reflex are carried to which nucleus of trigeminal nerve
a) Mesencephalic
b) Sensory
c) Motor
d) Spinal
Ans. a) Mesencephalic.
Explanation: Masseter reflex (jaw jerk) is elicited by hitting the mentum (mandible) down with the help of
a knee hammer. It is a proprioceptive reflex carried by the mandibular (trigeminal) nerve towards the
mesencephalic sensory nucleus of trigeminal, the fibres then reaching the motor nucleus of trigeminal in the
pons. Motor fibres carried by the trigeminal mandibular nerve activates the masseter muscle in turn, which
leads to elevation of the mandible.
36. Which of the following is/are projected to ventral posterior nucleus of thalamus (PGIC)
a) Lateral lemniscus
b) Medial lemniscus
c) Corticospinal tract
d) Spinal lemniscus
e) Trigeminal lemniscus
Ans. b) Medial lemniscus; d) Spinal lemniscus; e) Trigeminal lemniscus.
Explanation: Thalamus has a ventral posterior (VP) nucleus, which has two parts: medial and lateral. VPM
(Ventero-Posterior-Medial) nucleus receive sensory input from ‘head’ region, whereas VPL (Ventero-
Postero-Lateral) nucleus receive sensory information from the ‘body’. Trigeminal nerve (first order
neurone) carries information from the head region continues in the trigeminal lemniscus (second order
neurone in brainstem) and synapses on VPM nucleus of thalamus. Thalamus has third order neurones,
which in turn project on to the parietal sensory cortex (1,2,3). Spinothalamic tract- spinal lemniscal system
(pain, temperature) & dorsal column- medial lemniscal system (tactile discrimination,vibration etc.) carry
information from the ‘body’ region to synapse on VPL nucleus of thalamus, which further project the
information to area 1,2,3. Lateral lemniscus carry auditory pathway and synapses with medial geniculate
body (meta-thalamus).
37. All of the following pairs are correct for nuclei of hypothalamus EXCEPT
a) Ventero medial: Hunger
b) Supra-optic: Water conservation
c) Posterior nucleus : Shivering centre
d) Supra-chiasmatic: Circadian rhythm
PG-DIAMS ANATOMY 60
Anterior hypothalamus has osmoreceptors and centres like supra-optic nucleus secrete
vasopressin (ADH) for water conservation.
Ans. d) Pontocerebellar.
Explanation: Middle cerebellar peduncle has incoming (afferent) fibres from the contralateral pons (ponto-
cerebellar) fibres. Dentato-thalamic fibres pass through superior cerebellar peduncle from the dentate
nucleus to synapse in thalamus. Posterior spino-cerebellar and the olivo cerebellar fibres pass through
the inferior cerebellar peduncle.
Ans. c) Fastigi.
Explanation: According to evolution, the oldest and medial most is fastigii nucleus.
Dentate nucleus is the lateral most nuclei and the latest in evolution. It has crumbled bag appearance.
According to evolution, the flocculonodular lobe (vestibulocerebellum) is the oldest part and doesn’t
even connect with the deep cerebellar nuclei. It is involved in maintenance of equilibrium (balance
and spatial orientation) Damage to this region causes disturbances of gait.
NeuroAnatomy - II
Spinal Cord – Grey and White Matter
PG-DIAMS ANATOMY 63
42. All is true about sympathetic nervous system fibres arising from the spinal cord EXCEPT
a) Neurons are located in the intermedio-lateral column
b) Pre-ganglionic fibres are myelinated & shorter in length
c) Splanchnic nerves carry GVE and GVA neural columns
d) Splanchnic fibres carry postganglionic fibres
Spinal Nerves:
■ Consist of 31 pairs: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal.
■ Are formed from dorsal and ventral roots; each dorsal root has a ganglion that is within the intervertebral
foramen.
■ Are connected with the sympathetic chain ganglia by rami communicantes.
■ Contain sensory fibers with cell bodies in the dorsal root ganglion (general somatic afferent,GSA and
general visceral afferent,GVA) fibers), motor fibers with cell bodies in the anterior horn of the spinal cord
(general somatic efferent,GSE fibers), and motor fibers with cell bodies in the lateral horn of the spinal cord
(general visceral efferent,GVE fibers) between T1 and L2.
■ Are divided into the ventral and dorsal primary rami. The ventral primary rami enter into the formation of
plexuses (i.e., cervical, brachial, and lumbosacral); the dorsal primary rami innervate the skin and deep
muscles of the back.
Sympathetic Nerve Fibers:
■ Have preganglionic nerve cell bodies that are located in the lateral horn of the thoracic and upper lumbar
levels of the spinal cord.
■ Have preganglionic fibers that pass through ventral roots, spinal nerves, and white rami communicantes.
These fibers enter adjacent sympathetic chain ganglia, where they synapse or travel up or down the chain
to synapse in remote ganglia or run further through the splanchnic nerves to synapse in collateral ganglia,
located along the major abdominal blood vessels.
■ Have postganglionic fibers from the chain ganglia that return to spinal nerves by way of gray rami
communicantes and supply the skin with secretory fibers to sweat glands (sudomootor), motor fibers to
smooth muscles of the hair follicles (arrectores pilorum – pilomotor), and vasomotor fibers to the blood
vessels.
Dorsal column – Medial lemniscal system: First order neurons (dorsal root ganglion) carry the
information ipsilaterally in the dorsal column (fasciculus cuneatus and gracilis) to synapse on second
order neurons located in the gracile and cuneate nuclei of the caudal medulla. They give rise to axons
(internal arcuate fibers) that decussate and form medial lemniscus. The medial lemniscus crosses
midline and ascends through the contralateral brain stem and terminates in the ventral posterolateral
(VPL) nucleus of the thalamus.Third order neurons are located in the VPL nucleus of the thalamus.
They project through the posterior limb of the internal capsule to the postcentral gyrus (Brodmann’s
areas 3, 1, and 2).
PG-DIAMS ANATOMY 66
Lateral spinothalamic tract – Spinal lemniscal system: First order neurons (dorsal root ganglion)
fibres synapse on the posterior horn cells (second order neurone), which further send the fibres
decussating in the anterior white commisure and run as lateral spinothalamic tract (spinal cord) and
further as spinal lemniscus (in the brainstem). Third order neurons are located in the VPL nucleus of
the thalamus. They project through the posterior limb of the internal capsule to the postcentral gyrus
(Brodmann’s areas 3, 1, and 2).
PG-DIAMS ANATOMY 67
Pyramidal tract: Fibers arise from pyramidal neurons in layer 5 of the precentral gyrus, premotor
areas and somatic sensory cortex and descend through the posterior limb of internal capsule and
basis pedunculi, cross at the spinomedullary junction and form the lateral corticospinal tract in the
lateral funiculus of the spinal cord. They terminate on lower motor neurons in the ventral horn or on
interneurons. • Most muscles are represented in the contralateral motor cortex. However, some (such
as the muscles of the upper face, the muscles of mastication, and muscles of the larynx) are
represented bilaterally. • With the noted bilateral exceptions, lesion of the pyramidal tract above the
decussation results in spastic paralysis, loss of fine movements, and hyperreflexia on the
contralateral side. • Lesion of the corticospinal tract in the spinal cord results in ipsilateral
symptomology.
PG-DIAMS ANATOMY 68
ANS
44. Sweating is mediated by
a) Adrenal hormones
b) Sympathetic adrenergic system
c) Sympathetic cholinergic system
d) Parasympathetic cholinergic system
Acetylcholine (ACh) is the preganglionic neurotransmitter for both divisions of the ANS as well as the
postganglionic neurotransmitter of the parasympathetic neurons; the preganglionic receptors are
nicotinic, and the postganglionic are muscarinic in type.
Norepinephrine (NE) is the neurotransmitter of the postganglionic sympathetic neurons, except for
cholinergic neurons innervating the eccrine sweat glands.
45. All of the following statements about the vagus nerve are true EXCEPT that it
a) Supplies heart & lung
b) Carries postganglionic parasympathetic fibers
c) Innervates right two third of transverse colon
d) Stimulates peristalsis & relaxes sphincters
PG-DIAMS ANATOMY 69
Parasympathetic System
Preganglionic fibres for the sub-mandibular ganglion arise from superior salivatory nucleus.
PG-DIAMS ANATOMY 70
46. All of the following nuclei belong to GVE (General Visceral Efferent) EXCEPT
a) Edinger Westphal nucleus
b) Lacrimatory nucleus
c) Dorsal nucleus of vagus
d) Abducent
Sympathetic System
47. All are seen in Horner’s syndrome due to cavernous sinus pathology EXCEPT
a) Enophthalmos
b) Ptosis
c) Miosis
d) Anhydrosis
PG-DIAMS ANATOMY 71
PG-DIAMS ANATOMY 72
Occipital visual cortex has lines (striations) of Gennari, hence tremed as striate cortex. It is supplied
by posterior cerebral artery and additionally by middle cerebral artery.
PG-DIAMS ANATOMY 74
Optic pathway lesions: a. Optic nerve injury – leads to complete blindness in the involved eye; b.
Midline lesions (like pituitary tumour) results in bitemporal hemianopia (tunnel vision); c. A lesion in
the optic tract results in contralateral homonymous hemianopia; d. Cortical blindness due to an
artery block in posterior cerebral artery results in contralateral homonymous hemianopia with
maculkar sparing (macular area on brain has additional supply from middle cerebral artery).
PG-DIAMS ANATOMY 75
Wallenberg Syndrome
50. A 68-year-old woman presents in the emergency room with dizziness and nystagmus.
Examination reveals a loss of pain and temperature sensation over the right side of the face
and the left side of the body. The patient exhibits ataxia and intention tremor on the right in
both the upper and lower extremities and is unable to perform either the finger-to-nose or heel
to-shin tasks on the right. In addition, she is hoarse and demonstrates pupillary constriction
and drooping of the eyelid on the right. Finally, the right side of her face is drier than the left.
Following vascular blockage, necrotic damage in which of the following would explain the
patient’s hoarseness
a) Descending sympathetic pathways
b) Nucleus ambiguus
c) Spinal nucleus of trigeminal nerve
d) Inferior cerebellar peduncle
Questions: NeuroAnatomy - II
52. Primary motor area (Area no. 4) of brain is supplied by
a) Anterior cerebral artery
b) Middle cerebral artery
c) Anterior and middle cerebral artery
d) Anterior and posterior cerebral artery
Greater part of the lateral surface receives supply from middle cerebral artery, whereas medial
surface of cerebrum is majorly supplied by anterior cerebral artery. The upper limb and head are
represented on the lateral surface of the cortex in homunculus, whereas pelvis and lower limb are
on the medial surface of the hemispheres. Therefore, the motor and sensory functions of the lower
limb are supplied by the anterior cerebral artery while the motor and sensory functions of the upper
limb and head are supplied by the middle cerebral artery.
Complete sulcus is the one which is deep enough to reach the wall of the ventricle and raise an
elevation on the interior wall. Collateral sulcus produces an elevation called collateral eminence and
posterior part of calcarine sulcus raises the elevation known as calcar avis.
Central sulcus is a limiting suclus limiting frontal motor cortex from the parietal sensory cortex.
PG-DIAMS ANATOMY 77
Association fibers connect regions within the same hemisphere of the brain, whereas commissural
fibers are transverse fibers that connect the two hemispheres of the brain. Projection fibers project
from higher to lower centres (or vice versa) in CNS, for e.g., pyramidal tract.
Tapetum are the commisural fibres of corpus callosum (body) by which temporal lobes communicate.
55. Regarding anterior choroidal artery syndrome, all are true EXCEPT
a) Hemiparesis
b) Hemi-sensory loss
c) Predominant Involvement of anterior limb of internal capsule
d) Homonymous hemianopia
PG-DIAMS ANATOMY 78
56. All of the following pairs are correct for the artery supply to the lower parts of internal capsule
EXCEPT
a) Anterior limb: Recurrent branch of anterior cerebral artery
b) Genu: Internal carotid artery
c) Posterior limb: Anterior choroidal artery
d) Sublentiform part: Heubner’s artery
The main arteries supplying internal capsule are:
Middle cerebral artery
Anterior cerebral artery (including recurrent branch of Heubner)
Anterior choroidal artery
Internal capule also receive additional branches from internal carotid artery, posterior communicating
artery, posterior cerebral artery.
Upper (dorsal) part of the anterior limb, genu and the posterior limb are supplied by the striate
branches of middle cerebral artery.
Lower (ventral) part of internal capsule:
Anterior limb: Anterior cerebral artery (including recurrent branch of Heubner)
Genu: Internal carotid artery
Posterior limb: Anteriuor choroidal artery
Sublentiform and retrolentiform parts are chiefly supplied by supplied by anterior choroidal artery.
Dural venous sinuses are intradural spaces present between the external (periosteal layer) and the
internal (meningeal layer) of the dura mater, containing venous blood drained from the brain.
a. Superior sagittal sinus is located along the superior aspect of the falx cerebri. Arachnoid granulations
drain CSF from the subarachnoid space into the dural venous sinuses, protrude into its wall.
b. Inferior sagittal sinus is located along the inferior free edge of the falx cerebri.
c. Straight sinus (deeper venous drainage of brain) is formed by the meeting of the great cerebral vein of
Galen with inferior sagittal sinus.
d. Occipital sinus is present in the attached border of the tentorium cerebelli.
e. Confluence of sinuses receive three incoming channels (tributaries) SOS: Straight sinus, Occipital
sinus and Superior sagittal sinus.
f. Transverse sinus drains venous blood from the confluence of sinuses to the sigmoid sinus. It also
receives incoming channel (tributary) from superior petrosal sinus.
g. Sigmoid Sinus drains into the internal jugular vein.
h. Inferior petrosal sinus is the first tributary to internal jugular vein.
58. Septic emboli in facial vein can cause cavernous sinus thrombosis because facial vein makes
clinically important connections with the cavernous sinus. The most commonly involved
communicating vein is
a) Superior ophthalmic
b) Deep facial
c) Inferior ophthalmic
d) Pterygoid plexus of veins
Cavernous sinuses receive blood from the facial vein via the tributaries superior and inferior
ophthalmic veins. Bacteria in the facial veins enter the cavernous sinus via these veins. Bacteria in the
sphenoid and ethmoid sinuses can spread to the cavernous sinuses via the small emissary veins and
are the most common sites of primary infection resulting in septic cavernous sinus thrombosis.
PG-DIAMS ANATOMY 80
a) Mammillary body
b) Occulomotor nerve
c) Optic chiasma
d) Infundibulum
60. All are contents of interpeduncular fossa EXCEPT
a) Trochlear nerve
b) Tuber cinerium
c) Infundibular stalk
d) Posterior perforated substance
All structures at the floor of third ventricle belong to interpeduncular fossa except the optic
chiasma and tegmentum of the midbrain.
Additional Questions
61. Speech in words and not in sentence occurs due to the lesion of
a) Wernicke’s sensory speech area
b) Broca’s motor speech area
c) Arcuate fasciculus
d) Primary auditory area
Ans. b) Broca’s motor speech area.
Explanation: Speech in words and not in sentences is a feature suggesting hesitant speech, which
occurs Broca’s motor aphasia. The planning of movement of speech muscles is compromised and
muscles are unable to articulate properly to produce meaningful voice. In Wernicke’s sensory aphasia,
comprehension (understanding) of the language is compromised and the patient incessantly speaks in
irrelevant sentences, making little sense. Lesion in the arcuate fasciculus result in conduction aphasia,
with problems in repetiton of speech.
62. Which of the following is NOT carried by posterior column tract
a) Position sense
b) Temperature
c) Pressure
d) Vibration
Ans. b) Temperature.
Explanation: Posterior (dorsal) column carries sensations like pressure, vibration, tactile discrimination,
proprioception, stereognosis, conscious proprioception. Pain & temperature is carried by the lateral
spinothalamic tract.
63. Which of the following pathway is involved in the ability to recognize an unseen familiar object
placed in the hand
a) Dorsal spinocerebellar tract
b) Anterior spinothalamic tract
c) Posterior spinothalamic tract
d) Dorsal column
Ans. d) Dorsal column.
Explanation: Ability to recognise an unseen familiar object is known as stereognosis and is carried by the
dorsal column.
PG-DIAMS ANATOMY 81
64. An anterolateral cordotomy relieving pain in left leg is effective because it interrupts the
a) Left dorsal column
b) Right lateral spinothalamic tract
c) Left corticospinal tract
d) Left spinocerebellar tract
Ans. b) Right lateral spinothalamic tract.
Explanation: Pain from the left is carried by lateral spinothalamic tract, contra-laterally on the right side of
the spinal cord.
65. Most of the fibres in Pyramidal tract originate from
a) Primary motor cortex
b) Pre-motor cortex
c) Primary somato-sensory cortex
d) Supplementary motor cortex
Ans. c) Primary somato-sensory cortex.
Explanation: About 31% of the corticospinal tract neurons arise from the primary motor cortex. The
premotor cortex and supplementary motor cortex account for 29% of the corticospinal tract neurons. The
largest percentage of 40% originate in the parietal lobe and primary somatosensory area in the postcentral
gyrus.
Explanation: Dilator pupilae is supplied by sympathetic fibres, which arise from the inter-medio-lateral horn
of spinal cord segment T-1. These pre-ganglionic T-1 sympathetic fibres climb up the cervical sympathetic
chain and synapse in the superior (highest) cevical ganglion. Post ganglionic fibres make sympathetic
plexus around the internal carotid artery and reach the dilator pupullae muscle.
70. Which of the following is NOT a sign of stellate ganglion block
a) Miosis
b) Exophthalmus
c) Nasal congestion
d) Conjunctival redness
Ans. b) Exophthalmos.
Explanation: T- 1 sympathetic fibres pass through the stellate ganglion in the sympathetic chain and it’s
block results in features of Horner syndrome. Paralysis of dilator pupillae results in sphincter pupillae
activity becoming more prominent (miosis). Loss of T-1 sympathetic vaso-constriction results in vasodilation
and hypermia (Nasal congestion, conjunctival redness). Horner syndrome results in enophtlamos (and not
exophthalmos).
71. Superior salivatory nucleus controls all of the following glands EXCEPT
a) Lacrimal
b) Palatine
c) Sublingual salivary gland
d) Parotid salivary gland
Ans. d) Parotid salivary gland.
Explanation: Inferior salivatory nucleus located at the lower pons supply parotid salivary gland.
72. A 19 year old woman met with a car accident and sustained crushed internal injury in the
abdomen. The fibers in the vagus nerve are lesioned, which interferes with the functions of,
which of the following structure
a) Urinary bladder
b) Splenic flexure of colon
c) Kidney
d) Uterus
Ans. c) Kidney.
Explanation: Vagus nerve supplies till the kidney level. Pelvic viscera like urinary bladder, uterus are
supplied by nervi erigentes. Splenic flexure of colon belongs to hind gut, supplied by nervi erigentes.
73. NOT affected in posterior cerebral artery infarct is
a) Midbrain
b) Pons
c) Thalamus
d) Striate cortex
Ans. b) Pons.
Explanation: Pons are supplied by basilar artery. Midbrain is supplied by branches of posterior cerebral
artery and basilar artery. Thalamus is supplied by numerous arteries including posterior cerebral artery and
posterior communicating artery. Striate cortex is supplied by posterior cerebral arterya and additionally by
middle cerebral artery (macular area on brain).
74. All of the following arteries supply medulla EXCEPT
a) Anterior spinal artery
b) Anterior inferior cerebellar artery
c) Superior cerebellar
d) Basilar
Ans. c) Superior cerebellar.
Explanation: Medulla oblongata is supplied by numerous arteries (but not superior cerebellar). The
arteries supplying medulla are: Vertebral, anterior spinal, posterior spinal, posterior inferior cerebellar,
anterior inferior cerebellar, basilar etc.
75. Which is NOT a branch of the vertebral artery
a) Anterior spinal
b) Posterior spinal
c) Posterior inferior cerebellar artery
d) Anterior inferior cerebellar artery
PG-DIAMS ANATOMY 83
81. Left sided upper motor neuron lesion of facial nerve paralyzes
a) Right half of the face
b) Left half of the face
c) Right upper half of the face
d) Right lower half of the face
Ans. d) Right lower half of the face.
Explanation: Left sided upper motor neuron lesion (as might occur in Weber syndrome), will result in
contralateral (right sided) facial palsy, where only lower face is involved, since the upper face has bilateral
innervation. Lower face muscles like orbicularis oris have only contralateral innervation, as the left cortico-
bulbar tract is lesiones, they get paralysed. Upper face muscles like orbicularis oculi are functional, as they
are additionally innervated by right cortico-bulbar tract.
In Bell’s palsy (lower motor neuron lesion of facial nerve), both the upper face and lower face muscles are
paralysed on the same side (ipsilateral) of the lesion.
Embryology
EyeBall
1. Ciliaris muscle is derived from
a) Neural crest cells
b) Neural plate ectoderm
c) Surface ectoderm
d) Mesoderm
Pharyngeal Arches
3. Epiglottis develops from which branchial arch
a) Third
b) Fourth
c) Fifth
d) Sixth
PG-DIAMS ANATOMY 87
PG-DIAMS ANATOMY 88
Pharyngeal Pouches
4. Parafollicular C cells are derived from
a) Ultimo-branchial body
b) Pharyngeal pouch 4
c) Pharyngeal pouch 5
d) Neural crest cells
PG-DIAMS ANATOMY 89
8. Within the figure below of a cross section of an embryo at the level of primitive pharynx, which
of the following structures will give rise to inferior parathyroid
a) 1(inside)
b) 2(inside)
c) 3(inside)
d) 4(inside)
10. The taste pathway from circumvallate papillae of the tongue goes through
a) Chorda tympani branch of Facial nerve
b) Greater petrosal nerve branch of Facial nerve
c) Superior laryngeal branch of Vagus nerve
d) Lingual branch of Glossopharyngeal nerve
Cranial Cavity
11. Which of the following cranial nerves present in the posterior fossa
a) 3rd to 12th
b) 4th to 12th
c) 5th to 12th
d) 6th to 12th
PG-DIAMS ANATOMY 92
PG-DIAMS ANATOMY 93
13. Which of the following is a tributary as well as drainage channel to cavernous sinus
a) Superior ophthalmic vein
b) Inferior ophthalmic vein
c) Spheno-parietal sinus
d) Superficial middle meningeal vein
PG-DIAMS ANATOMY 94
14. Anterior ethmoidal nerve branch of nasociliary nerve supplies all EXCEPT
a) Dura mater in anterior cranial fossa
b) Ethmoidal cells
c) Internal nasal cavity
d) Maxillary sinus lining
PG-DIAMS ANATOMY 95
Middle meningeal artery is a branch of maxillary artery, which passes through foramen spinosum to
enter cranial cavity. It may be ruptured in skull fracture leading to extradural haemmorhage, which
requires an emergency removal of clot putting burr holes to save the patient.
16. Structure passing through the tendinous ring of Zinn
a) Superior ophthalmic vein
b) Trochlear nerve
c) Naso-ciliary nerve
d) Lacrimal nerve
Membrana tectoria is continuation of posterior longitudinal ligament on vertebral column and enters cranial
cavity passing through foramen magnum
Most of the palate, pharynx and larynx muscles are supplied by cranial part of accessory nerve (fibres
distributed by vagus nerve branches) with few exceptions like stylopharyngeus(9), and tensor
palati(5).
All the muscles of tongue are supplied by hypoglossal nerve(12) except palatoglossus (supplied by
cranial accessory nerve).
23. Right fourth arch artery gives rise to
a) Right subclavian artery
b) Common carotid artery
c) Internal carotid artery
d) External carotid artery
Double aortic arch occurs when an abnormal right aortic arch develops in addition to a left aortic arch
due to persistence of the distal portion of the right dorsal aorta. This forms a vascular ring around the
trachea and esophagus, which causes difficulties in breathing and swallowing.
25. Lesser petrosal nerve passes through
a) Foramen rotundum
b) Foramen ovale
c) Canaliculus innominatus
d) Foramen spinosum
26. Choose the INCORRECT statement about cranial nerves
a) Abducent has the longest intracranial course
b) Trochlear shows internal decussation
c) Olfactory is the shortest
d) Vagus has largest distribution
The primary (main) action of the superior oblique muscle is intorsion (internal rotation), the secondary
action is depression (primarily in the adducted position) and the tertiary action is abduction (lateral
rotation).
Superior oblique is inserted into the posterior part of the eyeball; when it contracts, the back of the
eyeball is elevated, and the front of the eyeball is depressed (particularly in the adducted position).
32. Following are the pairs describing skull foramina and the nerves passing through them. Choose
the INCORRECT pair
a) Foramen ovale: Mandibular nerve
b) Foramen spinosum: Maxillary nerve
c) Foramen spinosum: Nervus spinosus
d) Internal acoustic meatus: Nervus intermedius
e) Foramen lacerum: Greater petrosal nerve
Ans. b) Foramen spinosum: Maxillary nerve; e) Foramen lacerum: Greater petrosal nerve.
Explanation: In the foramen spinosum pass nervus spinosus (mandibular nerve branch) and middle
meningeal artery. Maxillary nerve passes through foramen rotundum to enter the pterygopalatine fossa.
Nervus intermedius is also called as Wrisberg nerve and is a component of facial nerve (passes internal
auditory meatus). No structure passes through foramen lacerum, but at the floor are seen internal carotid
artery with sympathetic plexus around, deep petrosal nerve joining greater petrosal nerve to form nerve
of pterygoid canal.
Explanation: Superior orbital fissure lets pass the three branches of ophthalmic nerve (and not the parent
nerve itself). The three branches are lacrimal, frontal and naso-ciliary nerves.
34. All of the following structures pass through optic foramen EXCEPT
a) Optic nerve
b) Ophthalmic artery
c) Ophthalmic nerve
d) Dura mater
Ans. c) Ophthalmic nerve.
Explanation: Ophthalmic nerve is a content of cavernous sinus, gives three branches, which pass
through superior orbital fissure to enter the orbit. Optic nerve passes along with the ophthalmic artery
through optic canal, which is an opening in the lesser wing of sphenoid at the apex of orbit. Optic nerve is
covered by meninges as it exits the optic canal.
*Medial wall (4 bones) of orbit is formed by maxilla, lacrimal bone, ethmoid and the sphenoid (body).
*Lateral wall (2 bones)of orbit is formed by the zygomatic bone, and sphenoid (greater wing).
*Roof (2 bones) of orbit has frontal bone and sphenoid (lesser wing)
*Superior orbital fissure is formed between the lateral wall and the roof of orbit.
*Inferior orbital fissure is formed between the medial wall and the floor of orbit. Maxillary nerve passes
through it to run at the floor of the orbit as inferior orbital nerve.
41. UNTRUE statement about orbital articulation is
a) Medial wall of orbit is formed by maxilla, sphenoid, ethmoid and the lacrimal bone
b) Floor is formed by maxilla, zygomatic and palatine bone
c) Lateral wall of orbit is formed by the zygomatic bone and greater wing of sphenoid
d) Inferior orbital fissure is formed between the roof and the lateral wall of orbit
Ans. d) Inferior orbital fissure is formed between the roof and the lateral wall of orbit.
Explanation: Superior (not inferior) orbital fissure is present between the roof and lateral wall of orbit.
Inferior orbital fissure is at the junction of floor and lateral wall of the orbit.
42. Optic canal is present in which part of sphenoid bone
a) Greater wing
b) Lesser wing
c) Body
d) Pterygoid
Ans. b) Lesser wing.
Explanation: Optic canal is an opening in the lesser wing of sphenoid, where it attaches to the body of
sphenoid.
43. Blow-out fracture is present in which wall of orbit (PGIC)
a) Lateral wall
b) Medial wall only
c) Floor only
d) Medial wall and floor
e) Roof
Ans. d) Medial wall and floor.
Explanation: Blow-out fractures are more commonly seen in the floor > medial wall of the orbit.
PG-DIAMS ANATOMY 105
Facial nerve has two parts: motor to facial expression muscles and nervus intermedius. The motor
part carries SVE component, while nervus intermedius carries GSA, SVA, and GVE fibers.
SVE: Facial nerve supplies the muscles of facial expression (second pharyngeal arch). The fibres arise
from the motor nucleus of facial nerve (pons), loop around the abducent nucleus (internal genu), raising
facial colliculus, exit the brain stem at the ponto-medullary junction, to enter the internal auditory
meatus, pass through the facial canal in the middle ear cavity, give a branch to stapedius muscle, exit
the skull through the stylomastoid foramen to innervate the stylohyoid muscle, the posterior belly of
the digastric muscle, and enter parotid salivary gland and then send branches to innervate the face
muscles.
Nervus intermedius (nerve of Wrisberg) carries fibres for taste, salivation, lacrimation, and general
sensation (from the external ear). The first-order sensory neurons are found in the geniculate ganglion
within the temporal bone.
GSA component brings general sensations from the posterior surface of the external ear through the
posterior auricular branch.
GVA fibers carry fibres from the soft palate and the adjacent pharyngeal wall.
SVA component carries taste has from palate and the anterior two-thirds of the tongue to the nucleus
tractus solitarius.
GVE component begins in the superior salivatory nucleus in the lower pons, carry preganglionic
parasympathetic secretomotor fibres to glands. a. Lacrimal pathway - Secretomotor fibres pass through
the nervus intermedius and greater petrosal nerves to the pterygopalatine (spheno-palatine) ganglion to
supply LNP (lacrimal, nasal, palatine) glands. b. Submandibular pathway - Secretomotor fibres pass
through the nervus intermedius and chorda tympani to the submandibular ganglion to innervate the
submandibular and sublingual salivary glands.
Chorda tympani is given in the middle ear cavity, runs medial to the tympanic membrane and malleus.
It contains the SVA and GVE (parasympathetic) fibers. It carries pre-ganglionic fibres and is joined by
lingual nerve (a branch of mandibular nerve), which carries post-ganglionic parasympathetic fibres to
reach the submandibular and sublingual salivary glands..
50. All is true about facial colliculus EXCEPT
a) Raised by axons of facial nerve internal genu
b) Abducent nucleus lies deep to it
c) Located at the floor of fourth ventricle
d) Present on the dorsal aspect of upper pons
52. Facial nerve has all the following neural columns EXCEPT
a) GVE
b) SVE
c) SVA
d) SSA
Hypoglossal Nerve
53. NOT seen in hypoglossal nerve injury
a) Atrophy of same side
b) Ipsilateral deviation of tongue
c) Loss of tactile sensation of anterior part of tongue
d) Larynx deviation toward the opposite side during swallowing
Complete division of hypoglossal nerve causes unilateral lingual paralysis and eventual hemi-
atrophy; the protruded tongue deviates to the paralysed side, on retraction, the wasted and paralysed
side rises higher than the unaffected side. The larynx may deviate towards the active side in
swallowing, due to unilateral paralysis of the hyoid depressors associated with loss of the first
cervical spinal nerve which runs with the hypoglossal nerve.
PG-DIAMS ANATOMY 109
Cervical Plexus
Larynx
54. FALSE about larynx
a) 9 cartilages: 3 paired and 3 unpaired cartilages
b) Extends from C3 to C6 vertebrae
c) External laryngeal nerve supply all larynx muscles except cricothyroid
d) Cricothyroid is a tensor of vocal cord
PG-DIAMS ANATOMY 110
55. Damage to the external laryngeal nerve during thyroid surgery could result in the inability to
a) Relax the vocal cords
b) Tense the vocal cords
c) Widen the rima glottidis
d) Abduct the vocal cords
Damage to the external laryngeal (branch of superior laryngeal) nerve can result when ligating the
superior thyroid artery during thyroidectomy. It can be avoided by ligating the superior thyroid artery at
its entrance into the thyroid gland. Injury to the nerve result in a weak voice with loss of projection, and
the vocal cord on the affected side appears flaccid.
Unilateral damage to the recurrent laryngeal nerve can result while ligating inferior thyroid artery
during thyroidectomy. It results in a hoarse voice, inability to speak for long periods, and movement of
the vocal fold on the affected side toward the midline.
Bilateral injury to the recurrent laryngeal nerve may result from while ligating inferior thyroid artery
during thyroidectomy. It results in acute breathlessness (dyspnea) since both vocal folds move toward
the midline and close off the air passage (and tracheostomy might be required).
Oesophagus
56. Marker ‘4’ in the following diagram shows oesophageal narrowing produced by
a) Crico-pharyngeus sphincter
b) Arch of aorta
c) Left principal bronchus
d) Left atrium
PG-DIAMS ANATOMY 111
Inferior thyroid veins drain into brachio-cephalic vein and are prone to injury in tracheostomy
procedure.
Posterior neck triangle is bounded by the trapezius, sternocleidomastoid, and clavicle and is
subdivided by the posterior belly of the omohyoid into the occipital and subclavian triangles. The
contents are spinal accessory nerve; cervical plexus; brachial plexus (roots and trunks); and subclavian,
transverse cervical & suprascapular arteries.
Anterior neck triangle is bounded by the sternocleidomastoid, mandible, and midline of the neck and
is subdivided by the anterior & posterior bellies of digastric anterior and anterior belly of the omohyoid
into the submandibular, carotid, muscular, and submental triangles.
PG-DIAMS ANATOMY 114
B. Anterior triangle
1. Carotid triangle Carotid sheath (containing common carotid artery,
Internal jugular vein and vagus nerve), Ansa
cervicalis, sympathetic trunk, CN – XI and XII
2. Submandibular (digastric) triangle Submandibular salivary gland, CN – XII, mylohyoid
nerve, facial artery
3. Sub-mental triangle Sub-mental lymph nodes
4. Musculat triangle Strap (ribbon) muscles: sternothyroid, sternohyoid
Brachial plexus can be blocked in the scalene triangle between scalenus anterior and medius.
Carotid triangle contains the bifurcation of the common carotid artery (into internal & external carotid
artery at the level of C4). Carotid body and sinus are be found at the bifurcation.
The carotid sheath contains the common and internal carotid arteries, internal jugular vein, and vagus
nerve. Sympathetic trunk lies posterior to the carotid sheath (embedded in the prevertebral fascia).
62. All is true about digastric triangle EXCEPT
a) On either side is anterior belly of digastric muscle
b) Floor is formed by mylohyoid muscle
c) Floor is formed by hyoglossus muscle
d) Contains mylohyoid nerve and vessels
PG-DIAMS ANATOMY 116
63. If there is a superficial cut in the region of middle part of posterior triangle of neck, patient will
experience problem in
a) Adduction of arm
b) Protraction of scapula
c) Shrugging of shoulder
d) Overhead abduction of arm
64. All is true about cervical fascia EXCEPT
a) Ligament of Berry fixes thyroid gland to cricoid cartilage
b) Prevertebral fascia forms the roof of posterior triangle
c) Ansa cervicalis is embedded in the anterior wall of carotid sheath
d) Carotid sheath is formed by pretracheal and prevertebral fascia
Deep cervical fascia forms a) investing layer, b) pretracheal layer and c) prevertebral layer.
a). Investing Layer encircles the neck and splits to enclose the trapezius and the sternocleidomastoid
muscles. It is at the roof of posterior triangle.
b). Pretracheal Layer surrounds the thyroid (and the parathyroid) glands, and encloses the infrahyoid
muscles.
c). Prevertebral Layer lies in front of the prevertebral muscles (like scalene muscles) behind the pharynx
& esophagus. It forms the floor of posterior triangl and extends laterally over the first rib into the axilla to
form axillary sheath (which encloses brachial brachial and axillary artery).
Carotid sheath is condensation of the prevertebral, pretracheal, and the investing layers of the deep
cervical fascia.
A thyroid mass usually moves with swallowing because the thyroid gland is enclosed by pretracheal
fascia.
PG-DIAMS ANATOMY 117
The nasolacrimal duct opens into the inferior meatus is partially covered by a mucosal fold (valve of
Hasner). Excess tears flow through nasolacrimal duct which drains into the inferior nasal meatus. It is
directed downward, backward and laterally.
Maxillary sinus opens into the middle meatus (hiatus semilunaris).
PG-DIAMS ANATOMY 119
72. Which of the following is the type of joints between malleus and incus
a) Primary cartilaginous
b) Secondary cartilaginous
c) Saddle synovial
d) Ball & socket synovial
Atlanto-occipital joint is an ellipsoid (condylar) synovial joint. Neck flexion and extension occurs at this
joint for the nodding (yes) movement.
Knee joint is a complex joint (involving more than two bones). Femoro-tibial joint structurally resembles
a hinge joint, but is considered as a condylar type of synovial joint between two condyles of the femur
and tibia. In addition, it includes a saddle joint between the femur and the patella.
Additional Questions
74. Nerve if Wrisberg carries (PGIC)
a) Motor fibres
b) Sensory fibres
c) Secretory fibres
d) Parasympathetic fibres
e) Sympathetic fibres
Ans. a) Motor fbres; b) Sensory fibres; c) Secretory fibres; d) Parasympathetic fibres.
Explanation: Nerve of Wrisberg (nervus intermedius) carry all the components of facial nerve except the
somatic motor fibres to the second pharyngeal arch (facial expression) muscles. Hence it carries
parasympathetic secreto-motor (GVE) fibres to the glands like lacrimal, palatine salivary glands etc. It
also carries sensory (GSA) fibres from the external ear canal. Taste (SVA) sensory fibres from palate and
anterior tongue are also carried along this nerve.
75. A patient has a dry eye and reduced nasal secretions. The location of a lesion might be in the
a) Otic ganglion
b) Pterygopalatine ganglion
c) Ciliary ganglion
d) Superior cervical ganglion
Ans. b) Pterygopalatine ganglion.
Explanation: Greater petrosal nerve (facial nerve branch) carries secretomotor fibres to the pterygo-
palatine ganglion which sends post-ganglionic fibres (along the trigeminal nerve branches) to supply
lacrimal, nasal and palatine glands. A lesion in pterygopalatine ganglion reults in dryness of eye, nose,
palate etc.
PG-DIAMS ANATOMY 120
76. Lacrimal secretions are decreased when facial nerve injury occurs at the following site
a) Middle ear
b) Mastoid foramen
c) Geniculate ganglion
d) Sphenopalatine ganglion
Ans. c) Geniculate ganglion.
Explanation: This question specifically mentions facial nerve injury, hence pterygopalatine(sphenopalatine)
ganglion cannot be the answer, since it is not in the course of facial nerve. Here the answer is geniculate
ganglion. Lesion of facial nerve at the geniculate ganglion compromises the secreto motor fibres towards
the lacrimal, nasal and palatine glands, leading to dryness in the areas.
77. All is true about chorda tympani EXCEPT
a) Facial nerve branch given in temporal bone
b) Carries post-ganglionic parasympathetic fibres
c) Carries secretomotor fibres to sublingual & submandibular salivary gland
d) Joins lingual nerve in infratemporal fossa
Ans. b) Carries post-ganglionic parasympathetic fibres.
Explanation: Chorda tympani nerve is the third branch of facial nerve (in the facial canal), given in the
middle ear cavity (temporal bone), it joins the lingual nerve in the infra-temporal fossa and reaches the
submandibular ganglion. Pre-ganglionic parasympathetic secretomotor fibres are carried by chorda
tympani nerve, synapse in the sub-mandibular ganglion, the post-ganglionic fibres pass along the lingual
nerve (branch of mandibular; trigeminal nerve) to supply the salivary glands (submandibular & sublingual).
78. Which of the following do NOT supply submandibular gland
a) Lingual nerve
b) Chorda tympani
c) Sympathetic plexus
d) Auriculotemporal nerve
Ans. d) Auricuotemporal nerve.
Explanation: Auriculotemporal nerve (a branch of mandibular; trigeminal) carries the post-ganglionic para-
sympathetic secretomotor fibres to supply the parotid (and not submandibular) salivary gland.
79. Parasympathetic secretomotor fibers to parotid come from all EXCEPT
a) Otic ganglion
b) Greater petrosal nerve
c) Auriculotemporal nerve
d) Tympanic plexus
Ans. b) Greater petrosal nerve.
Explanation: Parotid salivary gland is supplied by lesser petrosal nerve (and not greater petrosal nerve).
Inferior salivatory nucleus in the lower pons send preganglionic parasympathetic fibres along the
tympanic branch of glossopharyngeal nerve towards the tympanic plexus (in the middle ear cavity).
Lesser petrosal nerve carry pre-ganglionic fibres further from the tympanic plexus to the otic ganglion.
Otic ganglion send the post-ganglionic fibres along the auriculotemporal nerve (branch of mandibular;
trigeminal) to supply the parotid salivary gland.
80. Nerve supply to platysma is
a) Ansa cervicalis
b) Marginal mandibular branch of facial nerve
c) Cervical branch of facial nerve
d) Mandibular nerve
Ans. c) Cervical branch of facial nerve.
Explanation: Platysma muscle develops in second pharyngeal arch (nerve:facial) and is present in the
neck (cervical) region hence, is supplied by cervical branch of facial nerve.
81. The culprit muscle in sleep apnea syndrome is
a) Hyoglossus
b) Genioglossus
c) Posterior cricoarytenoid
d) Lateral cricoarytenoid
Ans. b) Genioglossus.
PG-DIAMS ANATOMY 121
Explanation: In sleep apnoea syndrome genioglossus muscle may not stay active during sleep and
tongue has the tendency to fall back into the respiratory pathway, leading to difficulty in breathing, which
wakes up the patient frequently during sleep.
82. Action of genioglossus
a) Elevation
b) Protrusion
c) Depression
d) Push the tongue towards midline
Ans. b) Protrusion > c) Depression and d) Push the tongue to midline.
Explanation: Genioglossus muscle pulls the tongue anterior and medial, thus protrusion in midlline
occurs. If one genioglossus muscle acts alone, the tip of the tongue deviates to the contralateral side, since
the medial vector is not being cancelled. Left genioglossus muscle acting alone turns the tip of tongue to
the right. Genioglossus muscle also pulls the tongue inferior (depression).
83. Incorrect statement(s) about tongue is/are (PGIC)
a) Facial nerve supplies fungiform papillae
b) Glossopharyngeal nerve supplies circumvallate papillae
c) Posterior most tongue develop from third pharyngeal arch
d) Genioglossus causes tongue protrusion
e) Blood supply is lingual artery
Ans. c) Posterior most tongue develop from third pharyngeal arch.
Explanation: Posterior most tongue develops in fourth pharyngeal arch and taste sensation is carried
by the superior laryngeal nerve (vagus branch). Fungiform papillae are present at the anterior aspect of
tongue and the taste sensation from the anterior 2/3 of tongue is carries by the chorda tympani (facial
nerve) branch. Posterior 1/3 of tongue develops in third pharyngeal arch and glossopharyngeal nerve
supplies the region (along with the circumvalate papillae). Genioglossus muscle takes the tongue
anterior, medial and inferior. Lingual artery is a branch of external carotid artery and supplies the tongue.
84. Ansa cervicalis innervates the following EXCEPT
a) Superior belly of omohyoid
b) Sternohyoid
c) Inferior belly of omohyoid
d) Thyrohyoid
Ans. d) Thyrohyoid.
Explanation: Ansa cervicalis supplies the anterior neck muscles, including strap muscles. Geniohyoid and
thyro-hyoid muscles (attaching to the hyoid bone) are supplied by C-1 fibres carried by hypoglossal nerve
(and not by ansa cervicalis).
]
92. If a benign tumour is found where the common carotid artery usually bifurcates, it would be
located at the level of the
a) Cricoid cartilage
b) Angle of the mandible
c) Superior border of the thyroid cartilage
d) Jugular notch
Ans. c) Superior border of thyroid cartilage.
Explanation: Carotid body tumour lies at the bifurcation of common carotid artery at the superior border
of thyrod cartilage.
93. All of the following are branches of subclavian artery EXCEPT
a) Vertebral artery
b) Thyrocervical trunk
c) Subscapular artery
d) Internal thoracic artery
Ans. c) Subscapular artery.
Explanation: First part of subclavian artery gives thre branches: V(Vertebral), I (Internal thoracic artery),
T(thyro-cervical trunk). Sub-scapular artery is a branch of axillary artery and goes under the scapula.
cavity. Medial 2/3 (24mm) is made up of elastic cartilage and opens in the naso-pharynx, behind the
inferior turbinate of nasal cavity.
It runs anterior, inferior and medial at an angle of 45°with the sagittal plane and 30°with the horizontal.
It is opened by dilator tubae (tensor veli palatini) and aided by salpingopharyngeus. Levator veli
palatini might allow passive opening.
The diameter of the tube is greatest at the pharyngeal orifice, least at the junction of the two parts (the
isthmus), and widens again towards the tympanic cavity.
Arteries to the pharyngotympanic tube arise from the ascending pharyngeal branch (external acrotid
artery branch), and from the middle meningeal artery & the artery of the pterygoid canal (maxillary
artery branches). The veins of the pharyngotympanic tube usually drain to the pterygoid venous
plexus.
It is supplied by tympanic plexus (which itself is chiefly contributed by glossopharyngeal nerve).
Recurrent tentorial nerve (a branch of ophthalmic division of trigeminal nerve) supplies tentorium
cerebelli.
Sensory supply to tonsil is by glossopharyngeal nerve and additional supply by lesser palatine
nerve (Trigeminal; maxillary nerve). Tonsillar pathology may be accompanied by pain referred to the
ear, due to common nerve supply (glossopharyngeal nerve).
Waldeyer’s ring is an arrangement of MALT (mucosa-associated lymphoid tissue) which surrounds
the openings into the digestive and respiratory tracts. It is made up antero-inferiorly by the lingual
tonsil, laterally by the palatine and tubal tonsils, and postero-superiorly by the nasopharyngeal
tonsil.
Cervical oesophagus is supplied by inferior thyroid artery.
Suprameatal triangle lies over the mastoid antrum.
PG-DIAMS ANATOMY 126
Section 5. Back
Back - Embryology
1. In a neonate, spinal cord ends at
a) Lower border of T12
b) Lower border of L I
c) Upper border of L 3
d) Lower border of L 3
In a neonate, at birth, spinal cord extends till the upper border of L-3 vertebra. It takes less than two
months (post birth) to reach the lower border of L-1 (Gray’s Anatomy).
2. Following are the various structures related to spinal cord and their respective terminal extent.
Choose the WRONG pair
a) Adult spinal cord: Transpyloric plane
b) Pia mater: Coccyx
c) Duramater: S2 vertebra
d) Arachnoid sheath: S2 vertebra
PG-DIAMS ANATOMY 127
3. During a procedure to remove cerebrospinal fluid from the subarachnoid space below the end of
the spinal cord, the needle was advanced too far and penetrated the ligament forming the anterior
border of the vertebral canal. Which of the following ligaments, not normally pierced during this
procedure, was accidentally penetrated
a) Anterior longitudinal
b) Ligamentum flava
c) Posterior longitudinal
d) Supraspinous
In lumbar puncture supraspinous and interspinous are always punctured, ligamentum flava may be
punctured (if the needle is not in the midline); posterior longitudinal ligament is punctured accidently
and anterior longitudinal ligament can never be punctured.
The spinal cord terminates at approximately the L1 vertebral level in 94% of individuals. In the remaining
6%, the conus extends to the L2-L3 interspace. LP is therefore performed at or below the L3-L4
interspace. A line drawn between the posterior superior iliac crests, which corresponds closely to the
level of the L3-L4 interspace is a guiding landmark.
In lumbar puncture needle penetrates duramater and arachnoid mater to reach CSF space for injecting
spinal anaesthesia.
The needle passes through skin → superficial fascia → supraspinous ligament → interspinous ligament
→ ligamentum flavum → epidural space → dura mater → arachnoid → subarachnoid space containing
CSF.
Internal vertebral venous plexuses lie within the vertebral canal in the epidural space.
4. Disc herniation between L4 and L5 involves nerve root
a) L- 2
b) L- 3
c) L- 4
d) L- 5
PG-DIAMS ANATOMY 128
In slip disc, a simple formulae to derive the affected nerve root is to add 1 to the upper vertebrae
number (valid in cervical and lumbar vertebrae region). Here, L4 (+1) = L5 nerve root is involved. Slip
disc is rarely seen in thoracic region.
Spinal cord has a cervical enlargement at spinal segment C3-T2, which contributes to brachial plexus
and supply the upper limb.
The lumbar enlargement is at spinal segment L1-S3, which gives fibres for the lumbo-scaral plexus to
supply the lower limb. Lumbar enlargement at the level of 9-12 thoracic vertebra.
The nerve roots exit at a level above their respective vertebral bodies in the cervical region (e.g., the
C7 nerve root exits at the C6-C7 level) and below their respective vertebral bodies in the thoracic and
lumbar regions (e.g., the T1 nerve root exits at the T1-T2 level). The cervical nerve roots follow a short
and horizontal intraspinal course before exiting. By contrast, the lumbar nerve roots follow a long and
oblique course and can be injured anywhere from the upper lumbar spine to their exit at the
intervertebral foramen.
Pain-sensitive structures of the spine include the periosteum of the vertebrae, dura, facet joints, annulus
fibrosus of the intervertebral disk, epidural veins and arteries, and the posterior longitudinal ligament.
PG-DIAMS ANATOMY 129
Additional Questions
5. Primary curvatures of vertebral column are
a) Cervical & lumbar
b) Thoracic & sacral
c) Cervical & thoracic
d) Thoracic & lumbar
Ans. b) Thoracic & sacral.
Explanation: Primary curvatures are present since birth and are concave anteriorly (kyphosis).
Secondary curvatures are acquired after birth and are convex (lordosis) anteriorly. Lumbar lordosis
increases during pregnancy due to centre of gravity shifting more anterior (additional load of conceptus).
C-1 (Atlas) vertebra has no body. C-2 (Axis) vertebra has a vertical projection (dens/odontoid
process), which articulates with atlas to form atlanto-axial joint (pivot synovial) for rotatory movement
of ‘NO’ at neck region.
Applied anatomy: Since, minimal muscle fibres lie over the triangle, auscultation by stethoscope is
better over this triangle, especially, the sounds of swallowed fluids. Cardiac end of the stomach lies
deep to this triangle.
Section 6. THORAX
Embryology
Cardiovascular tube develops from the ventral visceral (splanchnic) lateral plate mesoderm under
the influence of multiple signals, including those derived from neural crest cells.
The myocardial cells secretes an extracellular matrix rich in hyaluronic acid (cardiac jelly) which
accumulates within the endocardial cushions, which are precursors cardiac valves.
PG-DIAMS ANATOMY 133
The crista terminalis is the junction of the smooth and rough (trabeculated) part of the right atrium. It is
a vertical muscular ridge running anteriorly along the right atrial wall from the opening of the SVC to the
opening of the IVC, providing the origin of the pectinate muscles and is indicated externally by the sulcus
terminalis.
SA node is present in the right atrium at the opening of superior vena cava, at the upper end of crista
terminalis. It does not occupy the full thickness of the right atrial wall from epicardium to endocardium in
humans, but rather sits as a wedge of specialized tissue subepicardially.
Pulmonary veins (total four) develop from the left atrial wall.
Fetal circulation: Oxygenated blood travels from the placenta along the left umbilical vein. Most
blood by-passes the liver in the ductus venosus joining the inferior vena cava and then travelling to
the right atrium.
Most of the blood passes through the foramen ovale into the left atrium so that oxygenated blood can
enter the aorta and reach the brain at earliest. The remainder goes through the right ventricle with
returning systemic venous blood into the pulmonary trunk. The unexpanded lungs present high
resistance to flow so that blood in the pulmonary trunk tends to pass down the low-resistance ductus
arteriosus into the aorta.
Blood returns to the placenta via the umbilical arteries (branches of the internal iliac arteries).
At birth, when the baby breathes, the left atrial pressure rises, pushing the septum primum against the
septum secundum and closing the foramen ovale. Blood flow through the pulmonary artery increases
and becomes poorly oxygenated as it now receives systemic venous blood. Pulmonary vascular
resistance is abruptly lowered as lungs inflate and the ductus arteriosus is obliterated over the next
few hours to days.
At removal of placenta, ligation of the umbilical cord causes thrombosis of the umbilical arteries
(becomes medial umbilical ligaments), vein (becomes ligamentum teres) and ductus venosus
(Becomes ligamentum venosum).
Heart Arteries
PG-DIAMS ANATOMY 137
Right coronary artery arises from the anterior aortic sinus of ascending aorta and left coronary
artery from left posterior.
The term ‘dominant’ is used to refer to the coronary artery that gives the posterior interventricular
artery, which supplies the posterior part of the ventricular septum and often part of the posterolateral
wall of the left ventricle. The dominant artery is usually the right (60- 65%).
The first branch of right coronary artery is called as conus artery. This is sometimes termed a ‘third
coronary’ artery (may arise separately from the anterior aortic sinus in 36% of individuals or may be
a branch of left coronary artery occasionally).
The sinu-atrial node is supplied by the right (51–65%) or left (35–45%) coronary arteries, and fewer
than 10% of nodes receive a bilateral supply. The atrioventricular node is supplied by the right (80–
90%) or left (10–20%) coronary arteries.
3. The right coronary artery is the main supply to all of the following parts of the conducting system
in the heart EXCEPT
a) SA Node
b) AV Node
c) AV Bundle
d) Right bundle branch
PG-DIAMS ANATOMY 138
Veins: Thorax
The azygos vein is formed by the union of the right ascending lumbar and right subcostal veins. Its
lower end is connected to the IVC. It arches over the root of the right lung and empties into the SVC.
The hemiazygos vein is formed by the union of the left subcostal and ascending lumbar vein, receives
the 9th, 10th, and 11th posterior intercostal veins, and enters the azygos vein. Its lower end is
connected to the left renal vein. The accessory hemiazygos vein receives the fifth to eighth posterior
intercostal veins and terminates in the azygos vein.
The superior intercostal vein is formed by the second, third, and fourth intercostal veins and drains
into the azygos vein on the right and the brachiocephalic vein on the left.
4. IVC obstruction presents with
a) Oesophageal varices
b) Haemorrhoids
c) Para-umbilical dilatation
d) Thoraco-epigastric dilatation
Sternal Angle & Mediastinum
5. Arch of aorta begins at the vertebra level
a) T2
b) T3
c) T4
d) T5
PG-DIAMS ANATOMY 139
The sternal angle (of Louis) is the junction between the manubrium and the body of the sternum and
is located at the level where the second ribs articulate with the sternum, the aortic arch begins and
ends, and the trachea bifurcates into the right and left primary bronchi.
Trachea bifurcates at the upper border of T-5 vertebra (Gray’s Anatomy).
The posterior mediastinum contains the esophagus, thoracic aorta, azygos and hemiazygos veins,
thoracic duct, vagus nerves, sympathetic trunks, and splanchnic nerves.
6. Trachea bifurcates at the vertebra level
a) T2
b) T3
c) T4
d) T5
Trachea bifurcates at the upper border of T-5 vertebra, in deep inspiration may be pulled down to
T-6 vertebrae level. In a cadaver, it terminates at T-4 level.
The right principal bronchus is wider, shorter, and more vertical than the left principal bronchus, and
therefore, is where large aspirated objects commonly lodge. • The right lower lobar bronchus is most
vertical, most nearly continues the direction of the trachea, and is larger in diameter than the left, and
therefore, is where small aspirated objects commonly lodge and the fluid aspirations reach the right
lower lobes more often.
A bronchopulmonary segment is defined by a segmental bronchus and accompanying segmental
artery (branch of pulmonary artery) that lie centrally, whereas the veins (branch of pulmonary vein) are
intersegmental and lie at the margins of bronchopulmonary segments.
7. A bed-ridden patient on liquid diet develops aspiration pneumonia. Which of the following is
bronchopulmonary segment is most likely affected
a) Posterior of right upper lobe
b) Inferior lingular of left upper lobe
c) Apical of right lower lobe
d) Posterior of right lower lobe
In erect posture (sitting or standing) aspirated material most commonly enters the right lower lobar
bronchus and lodges within the posterior basal bronchopulmonary segment (no. 10) of the right lower
lobe.
Aspiration in supine posture most commonly involves the right lower lobar bronchus and aspitare
lodges within the superior(apical) bronchopulmonary segment of the right lower lobe.
PG-DIAMS ANATOMY 141
Intercostal Drainage
8. In pleural tap in the mid-axillary line, muscle NOT pierced is
a) External intercostal
b) Serratus anterior
c) Innermost intercostal
d) Transversus thoracis
PG-DIAMS ANATOMY 142
Rib - I
9. All of the following lie between first rib and the apex of the lung EXCEPT
a) Superior intercostal artery
b) First intercostal vein
c) Thoracic duct
d) Sympathetic trunk
Questions: Thorax
10. Which of the following is NOT a boundary of the Koch’s triangle
a) Tendon of Todaro
b) Limbus fossa ovalis
c) Coronary sinus
d) Tricuspid valve ring
Triangle of Koch : A roughly triangular area on the septal wall of the right atrium, bounded by the
base of the septal leaflet of the tricuspid valve, the anteromedial margin of the orifice of the
coronary sinus, and the tendon of Todaro; it marks the site of the atrioventricular node. In a case of
AV nodal re-entry tachycardia, radiofrequency ablation of this triangular area improves the symptoms.
Koch’s triangle is usually supplied by right coronary artery.
PG-DIAMS ANATOMY 143
a) Pulmonary trunk
b) Ascending aorta
c) Right auricle
d) Right ventricle
The lower border of the lung (midway between inspiration and expiration) crosses sixth rib in the
midclavicular line, eighth rib in the midaxillary line and tenth rib at the lateral border of erector spinae
(paravertebral line).
Additional Questions
13. UNTRUE about cardiac jelly (AIIMS)
a) Secreted by cardiac myocytes surrounding primitive heart tube
b) Found exterior to endothelium
c) Forms myocardium
d) Transforms into the connective tissue of the endocardium
Ans. c) Forms myocardium.
Explanation: Cardiac jelly is secreted by the cardiac myocytes (myocardium) around the endothelial lining
of heart tube, and transforms into the connective tissue of endocardium.
The primitive atrium is divided first by a septum primum, which grows down from the superior wall to
the atrio-ventricular cushions; as this fusion occurs, the midportion resorbs in the center forming the
ostium secundum. Rightward of the septum primum, a second septum secundum membrane grows
down from the ventral-cranial wall toward—but not reaching—the cushions, and covering most, but not
all, of the ostium secundum, resulting in a flap of the foramen ovale.
As the septum primum and septum secundum get fused with each other, foramen ovale in septum
secundum is closed (becomes fossa ovalis), at it’s floor is seen septum primum.
ASD: Secundum type ASD is the most common ASD. It is caused by either an excessive resorption of
the Septum primum or an underdevelopment and reduced size of the Septum secundum. Primum type
ASD is less common than secundum ASD and results from a failure of the septum premium to fuse with
the endocardial cushions
Atrial septal defect (ASD) : Fusion between septum primum and septum secundum takes place at
about 3 months after birth. Ostium secundum type: If septum secundum is too short to cover foramen
secundum (in the septum primum), it allows shunting of blood from left to right atrium (Atrial septal
defect). Ostium primum type: If septum primum fails to fuse with endocardial cushions, the defect lies
immediately above the atrioventricular (AV) boundary (may also be associated with a ventricular septal
defect).
PG-DIAMS ANATOMY 145
16. All of the following pairs for adult derivatives of embryonal structures is correct EXCEPT
a) Umbilical artery: Lateral umbilical ligament
b) Umbilical vein: Ligamentum teres
c) Ductus venosus: Ligamentum venosum
d) Foramen ovale: Fossa ovalis
Ans. a) Umbilical artery: Lateral umbilical ligament.
Explanation: Umbilical arteries become medial umbilical ligaments. Lateral umbilical ligaments are
raised by the inferior epigastric arteries. Median umbilical ligament is raised by urachus attaching to the
apex of urinary bladder.
Ans. d) 30 days.
Explanation: Physiological closure of ductus arteriosus occurs within 1 – 4 days of birth. Often a small
shunt of blood stays for 24-48 hours in a normal full term infant. At the end of 24 hours (one day), 20 %
ducts are functionally close, 82 % by 48 hours and 100% at 96 hours (4 days). Anatomical closure of
ductus arteriosus oocurs within 2 – 12 postnatal weeks (1 month to 3 months).
20. Anatomical closure of ductus arteriosus occurs at
a) 2 weeks
b) 4 weeks
c) 12 weeks
d) 16 weeks
Ans. c) 12 weeks.
Explanation: Anatomical closure of ductus arteriosus oocurs within 2 – 12 postnatal weeks (1 month to
3 months).
21. Cardiac defects causing right to left shunt, leading to early cyanosis are all EXCEPT
a) Transposition of great vessels
b) Tetralogy of Fallot
c) Patent ductus arteriosus
d) Persistent truncus arteriosus
Ans. c) Patent ductus arteriosus.
Explanation: PDA carries the blood towards the lungs and promotes oxygenation thus, reduces cyanosis.
AP septum anomalies like PTA, TGV and TOF present with right to left shunt, blood reaches systemic
circulation without proper oxygenation, hence leading to cyanosis.
22. Absence of cono-truncal septum gives rise to
a) Tetralogy of Fallot
b) Patent truncus arteriosus
c) Transposition of great vessels
d) Coarctation of aorta
Ans. b) Patent truncus arteriosus.
Explanation: Absence of Aorta Pulmonary (AP) septum leads to persistent (patent) truncus arteriosus.
Conotruncal septum is the other name for AP septum.
23. Pentalogy of Fallot is characterized by
a) Ventricular septal defect
b) Patent ductus arteriosus
c) Atrial septal defect
d) Pulmonary stenosis
Ans. c) Atrial septal defect.
Explanation: Tetrology plus ASD (Atrial Septal Defect) is a feature of pentalogy of Fallot.
24. The base of the heart is formed by
a) Left and right ventricle
b) Left atrium and ventricle
c) Right atrium and ventricle
d) Left and right atrium
PG-DIAMS ANATOMY 147
26. Bleeding comes from the vein that is accompanied by the posterior interventricular artery.
Which of the following veins is most likely to be ruptured
a) Great cardiac vein
b) Middle cardiac vein
c) Small cardiac vein
d) Oblique veins of the left atrium
Ans. b) Middle cardiac vein.
Explanation: Posterior interventricular artery is accompanied by middle cardiac vein, which itself
drains into the coronary sinus.
27. Even if thrombosis is present in the coronary sinus, which of the following cardiac veins might
remain normal in diameter
a) Middle cardiac vein
b) Anterior cardiac vein
c) Small cardiac vein
d) Oblique cardiac vein
PG-DIAMS ANATOMY 148
28. Occlusion of the left anterior descending artery will lead to infarction in which area of heart
a) Posterior part of the interventricular septum
b) Anterior wall of the left ventricle
c) Lateral part of the heart
d) Inferior surface of right ventricle
Explanation: Phrenic nerve passes anterior to the hilum of lungs, vagus nerve passes posterior to it.
Diaphragm receives somatic motor fibers solely from the phrenic nerve; its central part receives sensory
fibers from the phrenic nerve, whereas the peripheral part is supplied by intercostal nerves. Right dome of
diaphragm is at higher level (pushed up by liver) and the left dome of diaphragm is lower (pushed down by
heart).
Embryology
1. Limb buds appear at week
a) 3
b) 4
c) 5
d) 6
Upper limbs rotate laterally by 90 degrees, so that the thumb becomes lateral and little finger medial.
The flexor compartment comes anterior and the extensor compartment goes posterior.
Lower limb rotates medially by 90-degree, so the extensor aspect of the leg faces anteriorly.
Developmentally, radial artery is pre-axial and ulnar is a post-axial artery.
Brachial plexus
5. Which of the following is a branch from the trunk of brachial plexus
a) Dorsal scapular nerve
b) Long thoracic nerve
c) Nerve to subclavius
d) Suprascapular nerve
The nerve to subclavius is small and arises near the junction of the fifth and sixth cervical ventral rami.
PG-DIAMS ANATOMY 154
Brachial plexus is formed by the ventral primary rami of the lower four cervical nerves and the first
thoracic nerves (C5–T1). It has roots & trunks (in the neck), divisions (passing behind clavicle), cords
and branches (in the axilla). It is covered by a prolongation of prevertebral fascia (axillary sheath)
around the nerves in the axilla.
Two branches are given directly from the roots in the neck: 1. Dorsal scapular nerve (C5), which
supplies rhomboid major & monor levator scapulae muscles. 2. Long thoracic nerve of Bell (C5–
C7), which is given in the neck, enters axilla and descends on the external surface of the serratus
anterior muscle and supplies it.
Lateral cord gives three branches (LML), medial and posterior cords give 5 branches each. Radial
nerve is a branch of posterior cord (STARS) and supplies posterior (extensor) compartment of upper
limb. Ulnar nerve is a branch of medial cord (UM4) and runs on the ulnar (medial) side of the limb.
Median nerve runs in the midline of the limb and has contributions from both medial and lateral
cords.
Nerve Injuries
PG-DIAMS ANATOMY 155
PG-DIAMS ANATOMY 156
Radial nerve is the largest branch of brachial plexus. It carries all the five root values of brachial
plexus.
Ulnar nerve carries root value: C-7, 8; (T-1).
Hand of Benediction
PG-DIAMS ANATOMY 157
7. Which of the following is the most commonly damaged nerve in wrist slash injury (AIIMS)
a) Median
b) Ulnar
c) Radial
d) Anterior interosseous
Tinel sign is a tingling sensation in the distal end of a limb when percussion is made over the site of a
divided nerve. It indicates a partial lesion or the beginning regeneration of the nerve.
Phalen test : The size of the carpal tunnel is reduced by holding the affected hand with the wrist fully
flexed or extended for 30 to 60 seconds, or by placing a sphygmomanometer cuff on the involved arm
and inflating to a point between diastolic and systolic pressure; appearance of numbness or
paresthesias indicates carpal tunnel syndrome.
PG-DIAMS ANATOMY 159
Wrist drop
PG-DIAMS ANATOMY 161
13. Injury to radial nerve in lower part of spiral groove may result in all EXCEPT
a) Spare nerve supply to extensor carpi radialis longus
b) Results in paralysis of anconeus muscle
c) Leaves extension at elbow joint intact
d) Weakens supination movement
Explanation: Injury to radial nerve in lower part of radial groove results in paralysis (not sparing) of ECRL
(Extensor Carpi Radialis Longus). The muscle spared is triceps, and elbow extension is still possible.
Anconeus may (or may not) be paralysed, depending upon the involvement of the branch in the fracture.
Supinator muscle is paralysed , hence there will be difficulty in supination.
PG-DIAMS ANATOMY 162
Thyrocervical trunk is a branch from the first part of subclavian artery. It gives three branches SIT: S –
Supra-scapular artery; I – Inferior thyroid artery and T – Transverse cervical artery.
Axillary artery has three parts and 6 branches. First part (1 branch – superior thyroid artery); second
part (2 branches – thoraco-acromial and lateral thoracic artery) and third part (3 branches – anterior
and posterior circumflex humeral arteries and subscapular artery).
PG-DIAMS ANATOMY 163
Scapular Anastomosis
14. In a subclavian artery block at the outer border of first rib all of the following arteries help in
maintaining the circulation to upper limp EXCEPT
a) Thyrocervical trunk
b) Suprascapular
c) Subscapular
d) Superior thoracic
Allen Test
16. Allen’s test is done for checking
a) Neural disorders
b) Patency of ulnar artery
c) Patency of radial artery
d) Blood flow in cephalic vein
PG-DIAMS ANATOMY 164
Allen test is done to check the patency of the radial and ulnar arteries at the wrist and so determines
whether each individual artery is sufficient to maintain the arterial supply to the hand in isolation.
Questions: Upper Limb
17. All is true about clavicle EXCEPT
a) No marrow cavity
b) Long bone in horizontal disposition
c) Two secondary centres of ossification
d) Fractures at the junction of lateral and intermediate third
Long bones generally have one primary centre of ossification, clavicle bein an exception to have
double primary centre of ossification. Clavicle is a membranous bone (intra-membranous
ossification). Fracture of the clavicle may result from a fall on the shoulder or outstretched hand. The
fracture is most often in the middle third (at the junction of lateral 1/3 and medial 2/3) and results in
upward displacement of the proximal fragment pulled by the sternocleido-mastoid muscle and
downward displacement of the distal fragment by the deltoid muscle and gravity.
18. The accompanying x-ray shows the shoulder of an 11-year-old girl who fell off the monkey bars,
extending her arm in an attempt to break her fall. The small arrows indicate the fracture area.
The large arrows indicate which of the following
19. All the pairs about bony attachments around shoulder joint are correctly matched EXCEPT
a) Latissimus dorsi : Floor of intertubercular sulcus
b) Short head of biceps : Tip of coracoid process
c) Subscapularis : Lesser tubercle
d) Teres major : Greater tubercle
PG-DIAMS ANATOMY 165
Quadrangular space is bounded superiorly by the teres minor (and subscapularis muscle), inferiorly by
the teres major muscle, medially by the long head of the triceps, and laterally by the surgical neck of the
humerus. It transmits the axillary nerve and the posterior circumflex humeral vessels.
Upper triangular space is formed superiorly by the teres minor muscle, inferiorly by the teres major
muscle, and laterally by the long head of the triceps. Circumflex scapular vessels course through it.
Lower triangular space is bounded superiorly by the teres major muscle, medially by the long head of
the triceps and laterally by the shaft of the humerus (and medial head of the triceps). Radial nerve and
the profunda brachii (deep brachial) vessels course through it.
20. The accompanying artery with axillary nerve in the quadrangular space is
a) Anterior circumflex humeral artery
b) Posterior circumflex humeral artery
c) Profunda brachii artery
d) Circumflex scapular artery
21. The cubital fossa is bounded laterally by the muscle
a) Brachioradialis
b) Pronator teres
c) Brachialis
d) Supinator
PG-DIAMS ANATOMY 167
Cubital fossa is a triangular space on the anterior aspect of the elbow that is bounded by the
brachioradialis muscle laterally, pronator teres muscle medially, and superiorly by an imaginary
horizontal line connecting the two epicondyles of the humerus. At the floor are brachialis and
supinator muscles. The contents (in lateral to medial order) are the radial nerve, biceps tendon,
brachial artery, and median nerve. Ulnar nerve passes behind the medial epicondyle (not a content of
cubital fossa). At its lower end, the brachial artery divides into the radial and ulnar arteries.
Antecubital vein lies at the roof draining cephalic vein into the basilic vein.
22. WRONG about the first metacarpal is
a) Epiphysis is at the head
b) Base is convexo-concave for sellar synovial joint
c) Doesn’t articulate with other metacarpals
d) More anterior and medially rotated
Aberrant epiphyses are deviations from the norm (not always present). Epiphysis at the head of the
first metacarpal bone is an example.
PG-DIAMS ANATOMY 168
23. A 43 year old sportsperson suddenly notices that he can no longer hit his normal three-point
shot in basketball. He has been suffering some mild neck pain of 6 weeks duration with pain
down the back of his right arm and extending to the dorsal surface of his hand, including his
middle finger. He has diminished triceps tendon reflex on the right side. Which of the following
investigation is ordered, because you are concerned he has herniated which intervertebral
disk
a) Lateral x-ray; C6–C7
b) Cervical MRI; C6–C7
c) Cervical MRI; C8–T1
d) CT; C6–C7
24. Content of anatomical snuff box
a) Radial nerve
b) Radial artery
c) Cephalic vein
d) Abductor pollicis longus
Anatomic snuffbox is a triangular interval bounded antero-laterally by the abductor pollicis longus
(and extensor pollicis brevis) and postero-medially by the tendon of the extensor pollicis longus. it has
a floor formed by the styloid process of the radius, scaphoid, trapezium and the base of first
metacarpal bone. Radial artery is the content of the fossa, whereas, cephalic vein and cutaneous
branch of radial nerve lies on the roof.
De Quervain's tenosynovitis: Inflammation of the two tendons forming antero-lateral boundary of
anatomical snuff box. The tendons involved are abductor pollicis longus and extensor pollicis
brevis and Finkelstein test becomes positive.
Froment sign: Abnormal flexion of the distal phalanx of the thumb when a sheet of paper is held
between the thumb and the radial surface of the index finger; a sign of a lesion of the ulnar nerve.
PG-DIAMS ANATOMY 169
Froment sign indicates thumb adductor weakness and consists of flexion of the thumb at the
interphalangeal joint when attempting to oppose the thumb against the lateral border of the second
digit.
26. Mammary gland is supplied by (PGIC)
a) Subscapular artery
b) Musculo-phrenic artery
c) Internal mammary artery
d) Superior thoracic artery
e) Superior epigastric artery
Mammary gland receives blood from the axillary artery branches (lateral thoracic artery,
thoracoacromial artery); the posterior intercostal arteries and the internal thoracic (mammary)
artery branches.
27. The terminal axillary lymph nodes are
a) Apical
b) Central
c) Posterior
d) Anterior
Lymphatics from mammary gland drain predominantly (75%) into the axillary nodes, more specifically
to the pectoral (anterior) nodes (including drainage of the nipple). 20% lymphatics enter the
parasternal (internal thoracic) nodes, which lie along the internal thoracic artery/vein. Some
lymphatic vessels drains to the apical nodes and may connect to lymphatics draining the opposite
breast and to lymphatics draining the anterior abdominal wall.
Apical (medial or infraclavicular) nodes lie at the apex of the axilla (medial to the axillary vein) and
above the upper border of the pectoralis minor muscle, receive lymph from all of the other axillary
nodes and drain into the subclavian trunks.
PG-DIAMS ANATOMY 170
Mammary gland is supported by the suspensory ligaments (of Cooper), strong fibrous attachments,
from the dermis of the skin to the deep layer of the superficial fascia passing through the breast.
Breast cancer in advanced stages. infiltrates Cooper’s ligaments, produces shortening of the
ligaments, causing depression or dimpling of the overlying skin. Advanced sign of inflammatory breast
cancer, peau d’orange (texture of orange peel) is the edematous swollen and pitted breast skin due
to obstruction of the subcutaneous lymphatics.
28. All of the following structures pierce the clavipectoral fascia EXCEPT
a) Lateral pectoral nerve
b) Lateral thoracic artery
c) Cephalic vein
d) Axillary lymphatics
Clavipectoral fascia extends between the coracoid process, clavicle, and the thoracic wall and
envelops the subclavius and pectoralis minor muscles. It has a costocoracoid membrane, which lies
between the subclavius and pectoralis minor muscles and is pierced by the cephalic vein, the
thoracoacromial artery, and the lateral pectoral nerve.
29. Weight transmission from upper limb to axial skeleton is done by all EXCEPT (AIIMS)
a) Costo- clavicular ligament
b) Coraco-acromial ligament
c) Coraco-clavicular ligament
d) Inter-clavicular ligament
Additional Questions
31. Anterior axial line reaches till
a) Shoulder
b) Elbow
c) Wrist
d) Knuckle
Ans. c) Wrist.
Explanation: An axial line is the junction between two dermatomes supplied by discontinuous spinal
nerves. AAL (anterior axial line) starts from sternal angle (2nd rib) and reaches the wrist joint level. PAL
(posterior axial line) begins at shoulder and reaches the elbow joint level.
35. Claw hand is hyperextension at metacarpo-phalangeal joint & flexion at the interphalangeal(s).
Which muscles have become non-functional
a) Lumbricals
b) Lumbricals & palmar interossei
c) Lumbricals & dorsal interossei
d) Lumbricals and all interossei
PG-DIAMS ANATOMY 172
Ans. b) Ulnar.
Explanation: All the 8 interossei are supplied by the ulnar nerve.
Nerve involved Cause of injury Clinical features
Ulnar nerve Fracture medial Claw hand deformity; Weakness in wrist flexion;
epicondyle (humerus); hand deviates to radial side on flexion; flexion of
wrist slash injury ring and little finger is weak at distal IP joint; MCP
flexion and IP extension of ring & little finger lost;
loss of finger abduction and adduction; loss of
thumb adduction; sensory loss on palmar and
dorsal aspect of medial 1 & ½ fingers; Froment sign
positive, card test positive
Explanation: Composite (hybrid) muscles have more than one motor supply. Flexor carpi ulnaris is
supplied by only ulnar nerve. The other muscles mentioned in the question have additional nerve supply
from medial nerve as well.
39. While skiing, a person catches a tree to stop and suffers hyper-abduction injury. The neural
involvement is/are (PGIC)
a) C-8; T-1 nerve root
b) Upper trunk of brachial plexus
c) Lower trunk of brachial plexus
d) Ulnar nerve
e) Median nerve
Ans. a) C-8; T-1 nerve root; c) Lower trunk of brachial plexus; d) Ulnar nerve; e) Median nerve.
Explanation: This a case of Klumpke’s palsy (C-8; T-1 lesion) due to stretching of lower trunk of brachial
plexus. It leads to partial injury of median and ulnar nerve and muscles of the hand like lumbricals and
interossei are paralysed (claw hand deformity)
43. All of the following features can be observed after fracture of surgical neck of humerus, EXCEPT
a) Loss of rounded contour of shoulder
b) Loss of sensation on skin over the upper part of deltoid
c) Weakness of abduction at shoulder joint
d) Atrophy of deltoid muscle
Ans. b) Loss of sensation on skin over the upper part of deltoid.
Explanation: There is loss of sensation on C- 5 dermatome - the upper lateral aspect of arm (on the
lower half of the deltoid). Fracture surgical neck of humerus may damage axillary nerve leading to
PG-DIAMS ANATOMY 174
paralysis of deltoid (abduction) and teres minor (lateral rotation) problem at shoulder joint. Since deltoid
undergoes atrophy, rounded contour of shoulder is lost.
44. A patient is unable to adduct his thumb. The nerve involved is characterized by (PGIC)
a) Having C-8; T-1 root value
b) Arise from medial cord of brachial plexus
c) Arise from the medial and lateral cord of brachial plexus
d) Musician’s nerve
e) Supply first two lumbricals
Ans. a) Having C-8; T-1 root value; b) Arise from medial cord of brachial plexus; d) Musician’s
nerve.
Explanation: Loss of thumb adduction occurs due to paralysis of adductor pollicis (ulnar nerve lesion).
Ulnar nerve has C-(7), 8; T-1 root value, is the continuation of medial cord of brachial plexus, supplies
intrinsic muscles of the hand like all interossei and medial (last) two lumbricals, hence controls finer
movement of fingers for playing musical instruments (appropriately called musician’s nerve).
47. Pen test in the hand is performed to assess the neuromuscular status of
a) Opponens pollicis
b) Flexor pollicis brevis
c) Abductor pollicis brevis
d) 1st palmar interossei
Ans. c) Abductor pollicis brevis.
Explanation: Pen test is to check anterior abduction of thumb, carried out by abductor pollicis brevis
(median nerve supply).
Explanation: Long thoracic nerve arises directly from the roots of brachial plexus (C- 5, 6, 7). Posterior
cord of brachial plexus gives five branches (STARS): S – subscapular (upper), T - Thoracodorsal nerve, A
– Axillary nerve, R – Radial nerve, S – subscapular (lower).
The tendons of the second, third, and fourth digits have separate synovial sheaths so that the infection is
confined to the infected digit, but rupture of the proximal ends of these sheaths allows the infection to
spread to the midpalmar space. The synovial sheath of the little finger is usually continuous with the
common synovial sheath (ulnar bursa), and thus, tenosynovitis may spread to the common sheath and
thus through the palm and carpal tunnel to the forearm. Likewise, tenosynovitis in the thumb may spread
through the synovial sheath of the flexor pollicis longus (radial bursa).
PG-DIAMS ANATOMY 176
First lumbrical space communicates with thenar space whereas, 2, 3 and 4 lumbrical canals are
continuous with mid-palmar space.
Infection from thumb and index finger passes towards the thenar space along the first lumbrical canal.
Middle, ring finger and little finger drain towards mid palmar space along the 2, 3 & 4th lumbrical canals.
Ulnar bursa is the common synovial flexor sheath which envelops the tendons of both the flexor
digitorum superficialis and profundus muscles. Radial Bursa is the synovial flexor sheath for flexor
pollicis longus.
Thumb infection may lead to inflammation of the radial bursa, whereas, little finger infection involves the
ulnar bursa.
Fore arm space of Parona lies proximal to the flexor retinaculum and is continuous with the radial &
ulnar bursa.
Flexor retinaculum separates Fore arm space of Parona from the thenar & mid-palmar space and they are
non-continuous.
Note: Bursa is defined as a potential space lined by synovial membrane.
Section 8. Abdomen
Embryology
Umbilical Cord Contents
1. Which is NOT associated with vitello-intestinal duct
a) Ileal diverticulum
b) Umbilical sinus
c) Enterocystoma
d) Mesenteric cyst
Ileal (Meckel) diverticulum is found in about 2% of the population, located within 2 ft of the ileocecal
junction (on the anti-mesenteric side of the ileum), and is usually about 2 inches long. Often contain
two types of ectopic tissue (gastric and pancreatic). Peptic ulceration of adjacent ileal mucosa and
volvulus are complications.
PG-DIAMS ANATOMY 178
a) Omphalocele
b) Gastroschisis
c) Morgagnian hernia
d) Bochdalek hernia
There are 3 major openings in the diaphragm:(a) the vena caval hiatus, which lies in the central
tendon at the level of T-8 and transmits the IVC and the right phrenic nerve branches; (b) the
esophageal hiatus, which lies in the muscular part of the diaphragm at the level of T-10 and transmits
the esophagus, vagus nerve and branches of left gastric vessels; and (c) the aortic hiatus, which lies
between the two crura at the level of T-12 and transmits the aorta, thoracic duct, azygos vein, and
sometimes greater splanchnic nerve.
Right crus of diaphragm is longer than the left. Fibres of right crus surrounds the oesophagus at the
passage into the abdomen (? Sphincter action).
Gut Rotation
PG-DIAMS ANATOMY 182
11. The mesentery of small intestine, along its attachment to the posterior abdominal wall, crosses
all of the following structures EXCEPT
a) Left gonadal vessels
b) Third part of duodenum
c) Aorta
d) Right ureter
The root of the mesentery lies along a line running diagonally from the duodenojejunal flexure on the
left side of the second lumbar vertebral body to the right sacroiliac joint. The root crosses over the
third part of the duodenum, aorta, inferior vena cava, right ureter and right psoas major.
PG-DIAMS ANATOMY 183
PG-DIAMS ANATOMY 184
PG-DIAMS ANATOMY 185
The splanchnic nerves contain preganglionic sympathetic GVE fibers with cell bodies located in the
lateral horn (intermediolateral cell column) of the spinal cord and GVA fibers with cell bodies located in
the dorsal root ganglia.
PG-DIAMS ANATOMY 186
12. Which of the following is the terminal group of lymph node in colonic drainage
a) Preaortic
b) Intermediate
c) Para colic
d) Epicolic
13. Testicular lymphatics drain into which lymph nodes
a) Superficial inguinal
b) Internal iliac
c) Preaortic
d) Paraaortic
Gondas (testis and ovary) drain into the para-aortic lymph nodes→ cisterna chyli→thoracic duct
→Left jugulo-subclavian angle.
14. All is true about thoracic duct EXCEPT
a) Begins at level of T12
b) Enters thorax through aortic opening
c) Crosses from right to left at level of T8
d) Passes the superior aperture of thorax
e) Passes in posterior and superior mediastinum
PG-DIAMS ANATOMY 187
Right lymphatic duct begins as a convergence of the right subclavian lymph trunk, right jugular lymph
trunk, and right bronchomediastinal lymph trunk and terminates at right jugulo-subclavian angle at the
base of the neck. It drains right upper quadrant (RUQ) of the body: right side of the head & neck, right
thoracic region (including medial and lateral quadrant of right breast, right lung) and the right upper
limb.
PG-DIAMS ANATOMY 188
PG-DIAMS ANATOMY 189
17. In first stage of labour the referred pain from uterus is carried to the dermatome (AIIMS)
a) T-10, 11
b) T-12; L-1
c) L-1, 2
d) S-2, 3
Pain during first stage of labour is initially confined to T11 – T12 dermatomes (latent phase), but
eventually labour enters active phase and much of the pain is due to dilatation of cervix and lower
uterine segment and pain passes through hypogastric plexus and aortic plexus before entering the
spinal cord at T10 – L1 nerve roots. Stretching and compression of the pelvic and perineal structures
involves pudendal nerve (S2-4), so pain during second stage of labour involves T10 – S4
dermatomes.
18. To provide pain relief during first stage of labour which sensory level should be blocked
a) T8 to L1
b) T9 to L2
c) T10 to L1
d) T11 to L2
Spinal anesthesia up to spinal nerve T10 is necessary to block pain for vaginal Delivary and up to
spinal nerve T4 for cesarean section (due to the sympathetic fibre levels being at higher level than
motor or sensory blockade).
Questions: Abdomen- I
19. Hirschsprung’s disease is specifically known as
a) Congenital megacolon
b) Aganglionic megacolon
c) Congenital aganglionic megacolon
d) Congenital atretic aganglionic megacolon
Hirschsprung disease occurs due to non-migration of neural crest cells into the distal part of the gut
tube colon/rectum. There is absence of myenteric (Auerbach’s) ganglia, which is a parasympathetic
component for faecal evacuation. The diseased segment gets narrowed down and the normal
proximal segment is dilated (maga-colon) due to faecal retention. Rectal biopsy is a-ganglionic. The
presenting complaint is chronic constipation and on per rectal examination, there occurs sudden gush
of the retained faeces.
20. An infant presents with an omphalocele at birth. Which of the following applies to this condition
a) It is also seen in patients with aganglionic megacolon
b) It results from herniation at the site of regression of the right umbilical vein
c) It is caused by a failure of recanalization of the midgut part of the duodenum
d) It is caused by failure of the midgut to return to the abdominal cavity after herniation into the
umbilical stalk
PG-DIAMS ANATOMY 191
a) Normal
b) Non-rotation
c) Mixed rotation
d) Reverse rotation
24. A 46-year-old woman complains of significant abdominal pain that her physician thinks is
localized to the epigastric region. Which of the following organs is most likely involved in this
problem
a) Duodenum
b) Ileum
c) Kidney
d) Transverse colon
25. A 23-year-old female in good health suddenly doubles over with pain in the area of the
umbilicus. She feels warm and uneasy and has no appetite. The pain seems to have moved to
the lower right abdominal region, which nerves, perceived in the area of the umbilicus, most
likely carried the painful sensations into CNS
a) Vagus nerves
b) Lesser splanchnic nerves
c) 10th Intercostal nerve
d) Greater splanchnic nerves
Abdomen - II
Liver Segments
28. Liver is divided into anatomical segments by following all EXCEPT
a) Hepatic vein
b) Portal vein
c) Bile ducts
d) Hepatic artery
PG-DIAMS ANATOMY 194
29. All of the following segment of liver which drains into right hepatic duct EXCEPT
a) I
b) III
c) V
d) VIII
Arteries - Duodenum
30. Superior pancreatico-duodenal artery is a branch of
a) Superior mesenteric artery
b) Gastroduodenal artery
c) Celiac trunk
d) Inferior mesenteric artery
PG-DIAMS ANATOMY 195
The gastroduodenal artery is prone to erosion by posterior perforation of duodenal ulcer. Splenic
artery may be eroded by penetrating ulcer of the posterior wall of the stomach into the lesser sac.
Left gastric artery may be subjected to erosion by a penetrating ulcer of the lesser curvature of the
stomach.
Peritoneal cavity
31. A 32 year old computer operator with history of heartburn, develops sever excruciating pain in
the epigastric region. She is taken for immediate surgical exploration, which reveals evidence
of ruptured gastric ulcer. Where will the surgeon find the stomach contents
a) Omental bursa
b) Hepatorenal pouch of Morrison
c) Paracolic gutter
d) Pouch of Douglas
PG-DIAMS ANATOMY 196
38. While performing an operation in the region of femoral canal, the surgeon reaches the femoral
ring. All of the following statements describe the structures forming its boundaries EXCEPT
a) Lacunar ligament
b) Inguinal ligament
c) Pectineal ligament of Cooper
d) Falx inguinalis
PG-DIAMS ANATOMY 199
The femoral triangle is bounded by the inguinal ligament, the sartorius, and the adductor longus. Its
floor is formed by the iliopsoas, pectineus and adductor longus (& not the sartorius), and the roof is
formed by the fascia lata and cribriform fascia and contains the femoral artery and vein in the femoral
sheath but the femoral nerve outside it.
PG-DIAMS ANATOMY 200
The left renal vein may be compressed by an aneurysm of the superior mesenteric artery as the
vein crosses anterior to the aorta. Patients with compression of the left renal vein may result in renal
(and adrenal) hypertension on the left. A varicocele may also be found on the left side.
Questions: Abdomen - II
42. Calot’s triangle is bounded by all EXCEPT
a) Inferior surface of liver
b) Common hepatic duct
c) Cystic duct
d) Cystic artery
The cystic artery commonly arises from the right hepatic artery is the boundary for Calot’s triangle.
The triangle lies between three Cs - Common hepatic duct, Cystic duct, and Cystic artery. Inferior
surface of liver forms the boundary for the triangle of cholecystetctomy. In the angle between
Common hepatic duct and cystic duct lies the Callot’s lymph node of Lund, which gets inflammed in
cholecystitis.
44. Which of the following is present in the peritoneal reflection which forms one of the borders of
the paraduodenal fossa
a) Inferior mesenteric vein
b) Middle colic vein
c) Left colic vein
d) Splenic vein
The spermatic cord is surrounded by the external spermatic fascia, which is derived from the
aponeurosis of the external oblique abdominal muscle, the cremasteric fascia (cremaster muscle and
fascia) originating from the internal oblique abdominal muscle, and the internal spermatic fascia, which
is derived from the transversalis fascia.
Additional Questions
51. Liver is divided into two surgical halves by all EXCEPT
a) Cantlie’s line
b) Right hepatic vein
c) Portal vein at porta hepatis
d) Biliary duct at porta hepatis
Ans. b) Right hepatic vein.
Explanation: Liver is divided into two surgical halves by following middle hepatic vein (and not the right
hepatic vein)
PG-DIAMS ANATOMY 203
52. A Segmental resection was performed removing part of liver lying left of the falciform ligament.
The segments still retained in the left surgical liver are (AIIMS)
a) 2,3
b) 1,4
c) 2,4
d) 1,4,5
Ans. b) 1,4.
Explanation: During hepatic resection, segment 2 and 3 (lying left to the falciform ligament) have been
removed, and segment 1 and 4 are retained in the left surgical liver.
53. Regarding artery supply of pancreas, which of the following is/are correct (PGIC)
a) Both superior and inferior pancreatico-duodenal arteries are branches of gastro-duodenal artery
b) Posterior superior pancreatico-duodenal artery is a branch of superior mesenteric artery
c) Anterior inferior pancreatico-duodenal artery is a branch of superior mesenteric artery
d) Posterior inferior pancreatico-duodenal artery is a branch of gastro-duodenal artery
e) Body and tail are supplied by splenic artery
Ans. c) and e) .
Explanation: Gastroduodenal artery gives superior pancreatico-duodenal arteries (anterior and posterior
both). Superior mesenteric artery gives inferior pancreatico-duodenal arteries (anterior and posterior both).
Splenic artery runs on the superior border of pancreas and give multiple branches to body and tail of
pancreas.
54. Structures damaged while resecting the free edge of lesser omentum (PGIC)
a) Portal vein
b) Hepatic vein
c) Proper hepatic artery
d) Cystic duct
e) Common bile duct
Ans. a) Portal vein; c) Proper hepatic artery; e) Common bile duct.
Explanation: Free edge of lesser omentum contains the structures that enter the posrta hepatis (DAV). D –
Duct (Common bile), A- Artery (proper hepatic), V – Vein (portal).
55. A patient has a penetrating ulcer of the posterior wall of the first part of the duodenum. Which
blood vessel is subject to erosion
a) Common hepatic artery
b) Gastroduodenal artery
c) Proper hepatic artery
d) Anterior superior pancreatico-duodenal artery
Ans. b) Gastroduodenal artery.
Explanation: Gastroduodenal artery passes behind the first part of duodenum and is prone to bleeding in
posterior perforation of duodenal ulcer.
56. Wrong about ileum, as compared with jejunum is
a) Short club shaped villi
b) Long vasa recta
c) More lymphoid nodules
d) More fat in mesentery
Ans. b) Long vasa recta.
Explanation: Ileum has short vasa recta with relatively more arcades.
PG-DIAMS ANATOMY 204
Explanation: Hesselbach’s inguinal triangle is present on the anteroinferior abdominal wall bounded by
the rectus abdominis muscle, the inguinal ligament, and the inferior epigastric vessels.
Medial border: lateral margin of the rectus sheath (linea semilunaris); superolateral border: inferior
epigastric vessels; inferior border: inguinal ligament (Poupart's ligament).
It is the site in which a direct inguinal hernia begins.
62. Posterior wall of rectus sheath below the level of anterior superior iliac spine is formed by
a) Internal oblique
b) Transversus abdominis
c) Lacunar ligament
d) Fascia transversalis
Ans. d) Fascia transversalis.
Explanation: Rectus abdominis lies on the transversalis fascia below thr arcuate line.
The rectus sheath is the fibrous condensation of the aponeurotic layers on the anterior aspect of the
abdominal wall investing the rectus abdominis muscle. It also encloses the epigastric vessels, the inferior
five intercostal and subcostal vessels and nerves, and occasionally pyramidalis.
It is incomplete posteriorly at a level inferior to the arcuate line and superiorly above the costal margin.
The anterior wall is formed from the external oblique aponeurosis and a superficial layer of the internal
oblique aponeurosis where it divides at the lateral edge of the rectus abdominis muscle.
The posterior wall is formed from the aponeurosis of the transversus abdominis muscle where it joins the
deeper layer of the internal oblique aponeurosis. Together, both walls form the linea alba.
Since the tendons of the Obliquus internus and Transversus only reach as high as the costal margin, it
follows that above this level the sheath of the Rectus is deficient behind, the muscle resting directly on the
cartilages of the ribs, and being covered merely by the tendon of the Obliquus externus.
The Rectus, in the situation where its posterior sheath is deficient (below arcuate line), is separated from
the peritoneum only by the transversalis fascia, in contrast to the upper layers, where part of the internal
oblique also runs beneath the rectus. Because of the thinner layers below, this region is more susceptible
to herniation.
PG-DIAMS ANATOMY 206
Para-umbilical veins connects the left branch of the portal vein with the subcutaneous veins in the region
of the umbilicus.
The median umbilical fold or ligament contains the fibrous remnant of the obliterated urachus, the medial
umbilical fold contains the fibrous remnant of the obliterated umbilical artery, and the lateral umbilical fold
contains the inferior epigastric vessels.
A level of sensory blockade extending to the T 10 is desired in vaginal delivery (and T4 dermatome in
caesarean delivery). –William’s Obstetrics.
The adrenal gland receives arteries from three sources: the superior suprarenal artery from the inferior
phrenic artery, the middle suprarenal from the abdominal aorta, and the inferior suprarenal artery from the
renal artery. It is drained via the suprarenal vein, which empties into the IVC on the right and the renal
vein on the left.
The suprarenal and gonadal veins drain into the IVC on the right and the left renal vein. The azygos vein
is connected to the IVC, but the hemiazygos vein is connected to the left renal vein.
An obstruction in the flow through the portal system (valveless) may cause reversal of blood flow and
portal hypertension. Blood flows in a retrograde direction and pass through porto-systemic
anastomosis to reach the caval system. Sites for these anastomoses include the esophageal veins and
rectal veins leading to varices and thoracoepigastric veins leading to caput medusae.
Hepatic lobules are the small vascular units composing the substance of the liver, each of which is
polygonal, with a central vein at its center and portal canals peripherally at the corners. Portal lobule is a
triangular mass of liver tissue, larger than a liver acinus, containing portions of three adjacent hepatic
lobules, and having a portal vein at its center and a central vein peripherally at each corner.
PG-DIAMS ANATOMY 207
Liver acinus is a functional unit of the liver, smaller than a portal lobule, being a diamond-shaped mass
of liver parenchyma surrounding a portal tract. It consists of adjacent sectors of neighboring hexagonal
fields of classic lobules partially separated by distributing blood vessels. The zones, marked 1, 2, and 3,
are supplied with blood that is most oxygenated and richest in nutrients in zone 1 and least so in zone 3.
The terminal hepatic venules (central veins) in this interpretation are at the edges of the acinus instead of
in the center, as in the classic lobule. The vessels of the portal canals, namely, terminal branches of the
portal vein and hepatic artery that, along with the smallest bile ducts, make up the portal triad, are shown
at the corners of the hexagon that outlines the cross-sectioned profile of the classic lobule.
PG-DIAMS ANATOMY 208
Embryology
1. WRONG about genital system development is
a) Develop from mesoderm
b) Genital ridge forms at week 5
c) Testes develops earlier to ovary
d) External genitalia are fully differentiated at week 10
Genotype of the embryo is established at fertilization, but male and female embryos are
phenotypically indistinguishable till weeks 6. Testis starts developing at week 7, whereas ovarian
development begins at week 10. Male and female characteristics of the external genitalia can be
recognized by week 12. Phenotypic differentiation is completed by week 20.
Before the seventh week of gestation, the fetal gonads are not differentiated into either the male or
female genotype. Primordial germ cells migrate into the genital ridge (to form spermatocytes or
oocytes). The presence or absence of the Y chromosome (SRY gene - sex-determining region of the Y
chromosome) determine gonadal differentiation. All humans are destined to become females (default
mechanism) until interrupted by Y chromosome.
2. Trigone of urinary bladder develops from
a) Mesoderm
b) Ectoderm
c) Endoderm of urachus
d) Endoderm of urogenital sinus
Genitourinary system develops from Intermediate mesoderm. It forms the Urogenital ridges on each
side of the aorta. Three pairs of kidneys develop in cranio-caudal sequence in the urogenital ridge of
intermediate mesoderm: pronephros, mesonephros, and metanephros.
Pronephros regresses by the fifth week. Mesonephric duct (Mesonephros) at caudal end gives the
Ureteric bud (that later forms the ureter, renal pelvis, calyces, and collecting tubules).
Ureteric bud penetrate and induces Metanephros to develop into the adult kidney. Kidney is formed
during the fifth week from the metanephric mass (develops into nephrons for urine formation) and the
ureteric bud (collecting system).
Kidney develops in the pelvic cavity and ascends from sacral levels to lower thoracic levels later.
Mesonephric duct also give Wolffian duct (which develops into the efferent ductules, epididymal duct,
ductus deferens, ejaculatory duct and seminal vesicles). In females it gives vestigeal remnants:
epoophoron, paroophoron and Gartner’s duct.
Urogenital sinus forms the urinary bladder, urethra (and urethral and paraurethral glands, greater
vestibular glands) and lower vagina in females and urinary bladder, urethra (and prostate &
bulbourethral glands in males).
PG-DIAMS ANATOMY 209
Allantois is continuous with urinary bladder, later gets obliterated to form urachus (median umbilical
ligament).
Paramesonephric (Müllerian) ducts develop on the sides of Mesonephric duct and form uterine tubes
and the uterus, cervix, and upper vagina in females and form the prostatic utricle (and appendix of
testes) in males.
Prostate Gland
4. Urethral crest is due to
a) Opening of prostatic glands
b) Puboprostatic spread
c) Insertion of detrusor
d) Insertion of trigone
PG-DIAMS ANATOMY 213
Urogenital Diaphragm: It is a poorly defined structure, consists of the deep transverse perineal
muscle and the sphincter urethrae and is invested by superior and inferior fasciae. It stretches
between the two pubic rami and ischial rami but does not reach the pubic symphysis anteriorly. It is
pierced by the membranous urethra in the male and by the urethra and the vagina in the female.
Recently the existence of urogenital diaphragm has been challenged, suggesting it is not actually an
identifiable entity.
The deep perineal space (pouch) lies between the superior and inferior fasciae of the urogenital
diaphragm. It contains the deep transverse perineal muscle and sphincter urethrae, the
membranous part of the urethra, the bulbourethral gland of Cowper in the male, and branches of the
internal pudendal vessels and pudendal nerve.
The male external urethral sphincter is formed by two muscles: sphincter urethra and compressor
urethrae muscles, both in the deep perineal space. The female external urethral sphincter is formed by
three muscles: sphincter urethra, compressor urethrae, and urethrovaginalis muscles.
Bulbourethral (Cowper’s) glands lie among the fibers of the deep transverse perineal muscle in the
deep perineal pouch in the male, on the posterolateral sides of the membranous urethra. Ducts pass
through the inferior fascia of the urogenital diaphragm (perineal membrane) to open into the bulbous
portion of the spongy urethra.
The superficial perineal space (pouch) lies between the inferior fascia of the urogenital diaphragm
(perineal membrane) and the superficial perineal fascia (Colles’s fascia) and contains perineal
muscles, the crus of the penis or clitoris, the bulb of the penis or vestibule, the greater vestibular
glands of Bartholin in the female, branches of the internal pudendal vessels, and the pudendal nerve.
8. All is true about Bartholin gland EXCEPT
a) Homologous of male bulbo-urethral gland
b) Present in the superficial perineal pouch
c) Located at the junction of anterior 1/3 and middle 1/3 of labia majora
d) Opens into the vestibule between hymen and labia minora
PG-DIAMS ANATOMY 217
Bartholin duct opens in the postero-lateral wall of vagina (vestibule). In questions Lateral wall
> posterior wall.
The epithelium of the Bartholin duct is cuboidal near the gland, but becomes transitional and
finally stratified squamous near the opening of the duct.
Urethra rupture and Extravasation of Urine
9. A patient exposed to bomb explosion injury presents with rupture of the fundus of urinary
bladder. The extravasated urine reaches
a) Space of Retzius
b) Deep perineal pouch
c) Superficial perineal pouch
d) Peritoneal cavity
Rupture of the dome (superior wall) of the urinary bladder, leads to rupture of peritoneum and results in
an intraperitoneal extravasation of urine within the peritoneal cavity (ascites). It is caused by a
compressive force on a full bladder.
10. Injury to the male urethra above the perineal membrane due to a pelvic fracture, causes urine
to accumulate in all of the following EXCEPT
a) Space of Retzius
b) Deep perineal pouch
c) Superficial perineal pouch
d) Peritoneal cavity
PG-DIAMS ANATOMY 218
Rupture of membranous part of the urethra may lead to urine escaping into the space around the
prostate and bladder and extraperitoneal space. If the urogenital diaphragm is also disrupted urine
leaks into deep perineal space and into the superficial perineal space (as the perineal membrane
is also ruptured).
The most common type of urethral injury is at the junction of posterior and anterior (bulbous) urethra.
Radiologists consider a type III urethral injury as a combined anterior/posterior urethral injury.
11. A 16-year-old boy presents to the emergency department with straddle injury and rupture of the
bulbous urethra. Extravasated urine from this injury can spread into which of the following
structures
a) Scrotum
b) Ischiorectal fossa
c) Deep perineal space
d) Thigh
Extravasation of urine may result from rupture of the bulbous spongy urethra below the perineal
membrane; the urine may pass into the superficial perineal pouch and spread inferiorly into the
scrotum, anteriorly around the penis, and superiorly into the lower part of the abdominal wall. The
urine cannot spread laterally into the thigh because the perineal membrane and the superficial fascia of
the perineum are firmly attached to the ischiopubic rami and are connected with the deep fascia of the
thigh (fascia lata). It cannot spread posteriorly into the anal region (ischiorectal fossa) because the
perineal membrane and Colles’s fascia are continuous with each other around the superficial
transverse perineal muscles.
PG-DIAMS ANATOMY 219
12. After fracture of the penis (injury to the tunica albuginea) with intact Buck’s fascia, there occurs
hematoma at
a) The penis and scrotum
b) At the perineum in a butterfly shape
c) Penis, scrotum, perineum and lower part of anterior abdominal wall
d) Shaft of the penis only
If the Buck fascia is intact, penile ecchymosis is confined to the penile shaft. If the Buck fascia has
been violated, the swelling and ecchymosis are contained within the Colles’ fascia. In this instance, a
‘butterfly-pattern’ ecchymosis may be observed over the perineum, scrotum, and lower abdominal
wall.
The pudendal nerve (S2–S4) passes through the greater sciatic foramen (below the piriformis
muscle) and enters the gluteal region. Then passes through the lesser sciatic along with the internal
pudendal vessels to enter the pudendal canal, gives rise to the inferior rectal and perineal nerves, and
terminates as the dorsal nerve of the penis (or clitoris).
PG-DIAMS ANATOMY 220
PG-DIAMS ANATOMY 221
Pelvic diaphragm: Forms the pelvic floor and supports all of the pelvic viscera. It is formed by the
levator ani (pubococcygeus and ilio-coccygeus) and coccygeus (ischio-coccygeus) muscles and
their fascial coverings. It lies posterior and deep to the urogenital diaphragm and medial and deep to
the ischiorectal fossa.
PG-DIAMS ANATOMY 223
23. All are branches of anterior division of internal iliac artery EXCEPT
a) Ovarian
b) Vesical
c) Middle rectal
d) Pudendal
24. All are branches of posterior division of internal iliac artery EXCEPT
a) Superior vesical
b) Superior gluteal
c) Lateral sacral
d) Ilio-lumbar
25. All the following pairs are correct concerning the lymphatics of uterus EXCEPT
a) Fundus: Para-aortic
b) Mid-uterus: External iliac
c) Cervix: Superficial inguinal lymph nodes
d) Cervix: Sacral
PG-DIAMS ANATOMY 226
1. Fundus and upper part of the body: Pre- and para-aortic lymph nodes along the ovarian vessels (few
lymphatics from the lateral angles of the uterus travel along the round ligaments of the uterus and drain into
superficial inguinal lymph nodes .
2. Middle part of the body : External iliac nodes via broad ligament.
3. From cervix, on each side the lymph vessels drain in three directions:
Laterally: External iliac and obturator nodes.
Posterolaterally: Internal iliac nodes
Posteriorly: Sacral nodes
Additional Questions
26. Clitoris in females is embryologically derived from
a) Urogenital sinus
b) Genital swelling
c) Genital tubercle
d) Urogenital membrane
Ans. c) Genital tubercle.
Explanation: Glans penis and clitoris develop from the genital tubercle (phallus).
27. The transitional epithelium lining the urethra and the bladder is derived from
a) Mesoderm
b) Endoderm
c) Wall of the yolk sac
d) Paramesonephric duct
Ans. b) Endoderm.
Explanation: Epithelium of urinary bladder, urethra and vagina develop from endoderm of urogenital sinus.
28. Mullerian duct anomaly may include the absence of any of the following EXCEPT
a) Uterus
b) Vagina
c) Ovary
d) Uterine tube
Ans. c) Ovary.
Explanation: Ovaries develop from genital ridge.
PG-DIAMS ANATOMY 227
35. Root value of inferior rectal nerve supplying external anal sphincter is
a) L– 3, 4, 5
b) L– 5; S-1
c) S– 2, 3 4
d) S– 4, 5
Ans. c) S – 2, 3, 4.
Explanation: External anal sphincter is upplied by inferior rectal nerve branch of pudendal nerve.
36. All of the following pairs about the boundaries of ischiorectal fossa are correct EXCEPT
a) Anterior: Perineal membrane
b) Posterior: Gluteus maximus
c) Medial: Levator ani
d) Lateral: Obturator externus
Ans. d) Obturator externus.
Explanation: Obturator internus is present at the lateral wall of ischiorectal fossa. It is covered by
obturator fascia, which has pudendal canal in it.
Ans. b) A communication is present between the two IRF in front of anal canal
Explanation: A communication is present between the two IRF in behind the anal canal. The ischiorectal
fossa is separated from the pelvis by the levator ani and its fasciae and is bounded by the sphincter
urethrae and deep transverse perineal muscles (anteriorly), the gluteus maximus and the sacrotuberous
ligament (posteriorly), the sphincter ani externus and levator ani (superomedially), the obturator fascia
covering the obturator internus (laterally), and the skin (floor). Alcock’s pudendal canal is present in the
lateral wall of ischiorectal fossa and send inferior rectal nerve and vessels medially through the fossa
towards the anal canal.
39. Almost half of the females have which of the following type of pelvis
a) Anthropoid
b) Android
c) Platypelloid
d) Gynaecoid
Ans. d) Gynaecoid.
Explanation: The gynaecoid pelvis is the normal female type; its pelvic inlet typically has a rounded oval
shape and a wide transverse diameter. A platypelloid or markedly android (masculine or funnel-shaped)
pelvis in a woman may present with difficult vaginal delivery of a fetus.
The obstetric conjugate is the least anteroposterior diameter of the pelvic inlet from the sacral
promontory to a point a few millimeters below the superior margin of the pubic symphysis.
40. Artery supply to ureter is by all EXCEPT
a) Gonadal artery
b) Common iliac artery
c) External iliac artery
d) Vesical artery
Ans. c). External iliac artery.
Explanation: Ureter has numerous arteries supplying as shown in the diagram (but not external iliac).
41. Lymphatic drainage of distal spongy urethra is towards the lymph nodes
a) Superficial inguinal
b) Deep inguinal
c) External iliac
d) Internal iliac
Ans. b) Deep inguinal.
Explanation: Distal spongy urethra and the glans penis drain into the deep inguinal lymph nodes of
Cloquest and Rosenmuller.
PG-DIAMS ANATOMY 231
Rectum: Has a mucous membrane and a circular muscle layer that forms three permanent transverse
folds (Houston’s valves). Per rectal examination is performed for palpating for prostate, seminal vesicle,
ampulla of the ductus deferens, bladder, uterus, cervix, ovaries, perineal body etc.
Cremasteric artery (external spermatic artery) is a branch of the Inferior epigastric artery which
accompanies the spermatic cord, and supplies the cremaster and other coverings of the cord,
anastomosing with the testicular artery. In the females the cremasteric artery accompanies the round
ligament and is very small.
Corpora amylacea, are small hyaline masses (detected microscopically) found in the prostate gland,
neuroglia, and pulmonary alveoli. They are derived from degenerate cells or thickened secretions and
occur more frequently with advancing age.
Parts of fallopian tube (medial to lateral): Interstitial part→ Isthmus→ Ampulla→ Infundibulum.
Superior Hypogastric Plexus is the continuation of the aortic plexus below the aortic bifurcation and
receives the lower two lumbar splanchnic nerves. It bifurcates into the right and left hypogastric nerves in
front of the sacrum. It contains preganglionic and postganglionic sympathetic fibers, visceral afferent
fibers, and few, if any, parasympathetic fibers, which may run a recurrent course through the inferior
hypogastric plexus.
Hypogastric Nerve is the lateral extension of the superior hypogastric plexus and lies in the extra-
peritoneal connective tissue lateral to the rectum. It provides branches to the sigmoid colon and the
descending colon and is joined by the pelvic splanchnic nerves to form the inferior hypogastric or pelvic
plexus.
Inferior Hypogastric (Pelvic) Plexus is formed by the union of hypogastric, pelvic splanchnic, and sacral
splanchnic nerves and lies against the posterolateral pelvic wall, lateral to the rectum, vagina, and base of
PG-DIAMS ANATOMY 232
the bladder. it contains pelvic ganglia, in which both sympathetic and parasympathetic preganglionic
fibers synapse. It gives rise to rectal plexus, utero-vaginal plexus, vesical plexus, and prostatic plexus.
Sacral Splanchnic Nerves consist of preganglionic sympathetic fibers that come off the sympathetic
chain and synapse in the inferior hypogastric (pelvic) plexus.
Pelvic Splanchnic Nerves (Nervi Erigentes) arise from the sacral segment of the spinal cord (S2–S4)
and are the only splanchnic nerves that carry parasympathetic fibers. (All other splanchnic nerves are
sympathetic.) They contribute to the formation of the pelvic (or inferior hypogastric) plexus, and supply the
descending colon, sigmoid colon, and other viscera in the pelvis and perineum.
Pelvic fascia condensations as the supports of uterus: (1) Lateral or transverse cervical (Cardinal or
Mackenrodt’s) ligaments of the uterus extending from the cervix and the vagina to the lateral pelvic walls,
running laterally below the base of the broad ligament. (2) Pubocervical ligaments are bands of connective
tissue that extend from the posterior surface of the pubis to the cervix of the uterus. (3) Sacrocervical
ligaments extend from the lower end of the sacrum to the cervix and the upper end of the vagina. (4)
Rectouterine (Sacrouterine) Ligaments hold the cervix back and upward and sometimes elevate a shelf-
like fold of peritoneum (rectouterine fold), which passes from the isthmus of the uterus to the posterior wall
of the pelvis lateral to the rectum. It corresponds to the sacrogenital (rectoprostatic) fold in the male.
PG-DIAMS ANATOMY 233
Embryology
1. Root value of sciatic nerve is (AIPG)
a) L-1,2,3,4,5
b) L-2,3,4,5;S-1
c) L-3,4,5;S-1,2
d) L-4,5;S-1,2,3
Dermatomes
Lower limbs rotate medially by 90 degrees, the great toe becomes medial and little toe lateral. The
extensor compartment comes anterior and the flexor compartment becomes posterior.
The dorsal and ventral axial lines both reach the ankle joint (ventral reaches the medial aspect).
PG-DIAMS ANATOMY 234
Thigh Muscles
PG-DIAMS ANATOMY 235
\
PG-DIAMS ANATOMY 236
Superior gluteal nerve passes through the greater sciatic foramen (above the piriformis muscle) to
supply three muscles: gluteus medius, gluteus minimus and tensor fascia lata.
Gluteus maximus is supplied by inferior gluteal nerve which passes through greater sciatic
foramen, along with sciatic and pudendal nerve (all pass below piriformis muscle).
PG-DIAMS ANATOMY 239
4. In walking, gravity tends to tilt pelvis and trunk to the unsupported side, major factor in
preventing this unwanted movement is
a) Adductor muscles
b) Quadriceps
c) Gluteus maximus
d) Gluteus medius and minimus
Hybrid Muscles
5. Hybrid muscles are all EXCEPT
a) Pectineus
b) Adductor magnus
c) Tensor fascia lata
d) Biceps femoris
PG-DIAMS ANATOMY 240
Knee Joint
Terrible triad (MOI): Foot fixed, knee flexed, twisting fall. Lachman test is carried out at 20-30° of knee
flexion and is less painful. It has high sensitivity and specificity as compared with the original
anterior drawer test.
ACL and PCL are intracapsular but extrasynovial ligaments (lie inside the knee joint capsule but outside
the synovial cavity of the joint), still covered by synovial membrane.
ACL: Arises from the anterior intercondylar area of the tibia and passes backward, upward, and
laterally (BUL) to insert into the medial surface of the lateral femoral condyle.The anterior cruciate
ligament prevents forward sliding of the tibia on the femur (or posterior displacement of the femur on the
tibia) and prevents hyperextension of the knee joint. It is taut during extension of the knee and is lax
during flexion. It may be injured in hyperextension injuries.
Medial meniscus is also intracapsular but extrasynovial. It is C shaped (forms a semicircle) attaching
to the superior surface of tibia at intercondylar area, and is also attached to the medial collateral
ligament. It is more frequently torn in injuries than the lateral meniscus because of its strong attachment
to the tibial collateral ligament.
PG-DIAMS ANATOMY 241
Leg Muscles
Anterior leg muscles (Nerve: Deep peroneal nerve (L-5); Action: Foot extension/dorsiflexion
Muscle Additional Action
Tibialis anterior Foot inversion
Extensor digitorum longus Extends lateral 4 toes
Extensor hallucis longus Extends the great toe
Peroneus tertius Assists in foot eversion
PG-DIAMS ANATOMY 242
Posterior leg muscles; Nerve: Tibial nerve (L-4,5; S-1,2); Action: Plantarflexion of foot & toes
Muscle Additional Action
Gastrocnemius (S1,2) Knee flexion; plantar flexion at ankle (in extended
leg)
Plantaris(S1,2) Works with gastrocnemius
Soleus(S1,2) Plantar flexion at ankle
Popliteus (L4,5;S1) Knee flexion; medial rotation of tibia in unplanted
leg (unlock the knee)
Tibialis posterior(L4,5) Ankle plantarflexion; foot inversion
Flexor digitorum longus(S2,3) Ankle plantarflexion; lateral 4 toes flexion
Flexor hallucis longus(S2,3) Ankle plantarflexion; great toe flexion
LL - Nerve Injuries
PG-DIAMS ANATOMY 244
a) L-4
b) L-5
c) S-1
d) S-2
12. Posterior cutaneous nerve of thigh supplies skin overlying (PGIC)
a) Medial aspect of thigh
b) Posterior inferior aspect of buttock
c) Scrotum
d) Back of thigh
e) Popliteal fossa
The root value of posterior cutaneous nerve of thigh is S – 1, 2, 3.
13. Abduction of the thigh is limited by
a) Tension in the adductors
b) Tension in the adductors and iliofemoral ligament
c) Tension in the adductors and pubofemoral ligament
d) Tension in the adductors and ischiofemoral ligament
PG-DIAMS ANATOMY 246
Pubofemoral ligament reinforces the fibrous capsule inferiorly, extends from the pubis bone to the
femoral neck, and limits abduction and extension.
14. Identify the marked muscle in the gluteal region
a) Obturator externus
b) Obturator internus
c) Quadratus femoris
d) Piriformis
15. Structures passing through lesser sciatic foramen (PGIC)
a) Internal pudendal vessels
b) Obturator internus muscle
c) Pudendal nerve
d) Nerve to obturator internus
e) Pyriformis muscle
PIN (Pudendal nerve, Internal pudendal vessels and Nerve to obturator internus) structures come from
pelvic cavity, pass through the greater sciatic notch, hook behind the ischial spine (in gluteal region)
and move into the lesser sciatic notch. The tendon (and not muscle) of obturator internus passes
through the lesser sciatic notch.
PG-DIAMS ANATOMY 247
16. All of the following pairs regarding adductor canal are true EXCEPT
a) Roof: Sartorius muscle
b) Contents: Femoral nerve
c) Floor: Adductor longus and magnus
d) Antero-lateral boundary: Vastus medialis
Adductor canal (Sub-sartorial/Hunter’s canal): This passes from the apex of the femoral triangle to the
popliteal fossa.
18. All of the following pairs for boundaries of popliteal fossa are correct EXCEPT
a) Supero-medial boundary: semimembranosus
b) Supero-lateral boundary: Biceps femoris
c) Infero-lateral: Gastrocnemius and plantaris
d) Infero-medial: Gastrocnemius and soleus
PG-DIAMS ANATOMY 248
The popliteal fossa is the diamond-shaped space bounded superomedially by the semimembranosus
and semitendinosus, superolaterally by the biceps femoris, inferomedially by the medial head of the
gastrocnemius, and inferolaterally by the lateral head of the gastrocnemius and plantaris. It contains the
popliteal vessels, the common peroneal and tibial nerves, and the small saphenous vein.
19. In the following nutrient arteries to bones, choose the WRONG pair
a) Humerus : Profunda brachii
b) Radius: Anterior interosseous
c) Fibula: Peroneal
d) Tibia: Anterior tibial
Medial (Deltoid) Ligament of ankle joint is attached to the medial malleolus on tibia. It has four parts:
the tibionavicular, tibiocalcaneal, anterior tibiotalar, and posterior tibiotalar ligaments. It prevents
overeversion of the foot and helps maintain the medial longitudinal arch.
Calcaneus bone has a shelf-like medial projection called the sustentaculum tali, which supports the
head of the talus (with the spring ligament) and has a groove on its inferior surface for the tendon of
flexor hallucis longus (which uses the sustentaculum tali as a pulley).
The plantar calcaneonavicular (spring) ligament passes from the sustentaculum tali of the calcaneus
to the navicular bone. It supports the head of the talus and thereby maintains medial longitudinal
plantar arch. Laxity of this ligament results in fallen arches (flat feet).
Avulsion or rupture of the Achilles tendon disables the triceps surae (gastrocnemius and soleus)
muscles; thus, the patient is unable to plantar flex the foot.
Flexor retinaculum is a band of deep fascia , passes between the medial malleolus and the medial
surface of the calcaneus and forms the tarsal tunnel with tarsal bones for the tibial nerve, posterior
tibial vessels, and flexor tendons. It holds three tendons and blood vessels and a nerve in place
deep to it (from anterior to posterior): the tibialis posterior, flexor digitorum longus, posterior tibial artery
and vein, tibial nerve, and flexor hallucis longus (mnemonic: Tom, Dick ANd Harry).
Tarsal tunnel syndrome is a complex symptom resulting from compression of the tibial nerve or its
medial and lateral plantar branches in the tarsal tunnel, with pain, numbness, and tingling sensations
on the ankle, heel, and sole of the foot. It may be caused by repetitive stress with activities, flat feet, or
excess weight.
Extensor retinaculum: Bands of deep fascia , under which pass the tendons of the tibialis anterior,
extensor digitorum longus, extensor hallucis longus and the peroneus tertius. Inferior extensor
retinaculum is ‘Y’ shaped.
PG-DIAMS ANATOMY 250
22. All of the following pairs concerning layers of sole muscles are correct EXCEPT
a) First layer: Adductor hallucis
b) Second layer: Lumbricals
c) Third layer: Flexor hallucis
d) Fourth layer: Interossei
I – Abductor Hallucis II - Lumbricals
III – Adductor and flexor hallucis IV – Interossei (Deepest)
Lumbricals and interossei flex the MTP and extend the IP joints. Their paralysis might result in claw
foot.
Adductor hallucis muscle is located in the third layerof foot and help in maintenance of transverse
plantar arch.
PG-DIAMS ANATOMY 251
Additional Questions
23. Hip flexion is done by all EXCEPT
a) Ilio-psoas
b) Pectineus
c) Sartorius
d) Semitendinosus
Ans. d) Semitendinosus.
Explanation: Hip flexion is chiefly carried out by ilio-psoas muscle and assisted by muscles like
pectineus, sartorius etc. Semitendinosus is a hamstring muscle for hip extension along with the gluteus
maximus.
Explanation: Popliteus muscle has intracapsular origin from the lateral condyle of femur, has attachment
with the lateral lemniscus (not medial) and inserts into the posterior surface of tibia (floor of popliteal fossa).
It is supplied by tibial nerve and unlocks the knee joint by medial rotation of tibia (in unplanted foot). It
also works with hamstring muscles for knee flexion.
28. A boy playing football received a blow to the lateral aspect of the knee and suffered a twisting
fall. His medial meniscus is damaged, which other structure is most likely to be injured
a) Deltoid ligament
b) Posterior cruciate ligament
c) Anterior cruciate ligament
d) Patellar-ligament
29. Following are the nerves and muscles of the leg. Choose the CORRECT pair
a) Superficial peroneal: Soleus
b) Deep peroneal: Peroneus brevis
c) Tibial nerve: Tibialis anterior
d) Common fibular nerve: Short head of biceps
Ans. d) Common fibular nerve: Short head of biceps..
Explanation: Short head of biceps is supplied by the common peroneal nerve. Soleus is calf muscle
suppled by posterior tibila nerve. Peroneus brevis is a lateral leg muscles innervated by superficial peroneal
nerve. Tibialis anterior is supplied by deep peronela nerve.
30. Postero-lateral herniation of nucleus pulposus at L5 – S1 vertebrae level will result in pain
located along the
a) Anterior aspect of the thigh
b) Medial aspect of the thigh
c) Antero-medial aspect of the leg
d) Lateral side of the foot
Ans. d) Lateral side of the foot.
Explanation: The nerve root involved is S-1, and the corresponding dermatome involved is the lateral side
of the foot and little toe.
Ans. b) Cuboid.
Explanation: Cuboid bone is present at the lateral aspect of the foot, articulates with calcaneum (CC joint
is saddle synovial) and both bones contributes to lateral longitudinal arch. Cuboid bone is the keystone
bone for the arch. Cuboid bone has a groove for the tendon of peroneus longus muscle.
Lateral longitudinal arch is contributed by the calcaneus, the cuboid bone, and the lateral two
metatarsal bones. The keystone is the cuboid bone. It is supported by the peroneus longus tendon
and the long and short plantar ligaments.
Medial longitudinal arch is contributed and maintained by the of the talus, calcaneus, navicular,
cuneiform, and three medial metatarsal bones. The keystone is the head of the talus, which is located
at the summit between the sustentaculum tali and the navicular bone. It is supported by the spring
ligament and the tendon of the flexor hallucis longus. Flat foot (pes planus or talipes planus) is a
condition of disappearance or collapse of the medial longitudinal arch with eversion and abduction of
the forefoot and leads to pain as a result of stretching of the plantar muscles and straining of the spring
ligament and the long and short plantar ligaments.
Transverse arches: . 1. Proximal (metatarsal) arch is formed by the navicular bone, the three
cuneiform bones, the cuboid bone, and the bases of the five metatarsal bones of the foot. It is
supported by the tendon of the peroneus longus. 2. Distal arch is formed by the heads of five metatarsal
bones. It is maintained by the transverse head of the adductor hallucis.
37. Inversion & eversion mainly happen at which joint
a) Inferior tibio-fibular
b) Ankle
c) Subtalar
d) Calcaneo-cuboid
PG-DIAMS ANATOMY 255
Ans. c) Sub-talar.
Explanation: Subtalar (Talocalcaneal) joint It is a plane synovial joint (part of the talocalcaneonavicular
joint), and is formed between talus and calcaneus bones. Inversion and eversion of the foot occurs at this
joint.
39. All of the following pass under the flexor retinaculum EXCEPT
a) Tibialis anterior
b) Tibialis posterior
c) Posterior tibial artery
d) Deep peroneal nerve
e) Anterior tibial nerve
Ans. A) Tibilais anterior; d) Deep peroneal nerve; e) Anterior tibial nerve
Explanation: Tibialis anterior and deep peroneal (anterior tibial) nerve pass under the anteriorly placed
extensor retinaculum.
40. In foot pronation, the axis of which two joints become parallel
a) Talo-calcaneal and talo- navicular
b) Talo-calcaneal and calcaneo -cuboid
c) Subtalar and Lisfranc
d) Talo-navicular and calcaneo-cuboid
Saphenous Nerve is a branch of femoral nerve given in the femoral triangle and descends with the
femoral vessels through the femoral triangle and the adductor canal. Then it is accompanied by the
great saphenous vein to reach the medial margin of the foot. Innervates the skin on the medial side of
the leg and foot. It is vulnerable to injury during venesection at the medial malleolus.
Pott’s (Dupuytren’s) fracture is caused by forced eversion of foot and involves the lower end of the
fibula, often accompanied by fracture of the medial malleolus (or rupture of the deltoid ligament).
Most stable position for ankle joint is in dorsiflexion, when anterior wider part of talus(trochlear
surface) fits properly in tibio-fibular mortise.
Obturator externus is supplied by lumbar plexus (obturator nerve).
Tibio-femoral condyles are involved in weight transmission (pressure epiphysis) and are intracapsular.
PG-DIAMS ANATOMY 257
Q. A man comes with aphasia, is unable to name things and repetition is poor. However
comprehension, fluency and articulation is unaffected. He is probably suffering from (AIIMS)
a) Anomic aphasia
b) Transcortical sensory aphasia
c) Conduction aphasia
d) Broca's aphasia
PG-DIAMS ANATOMY 258
PG-DIAMS ANATOMY 259
PG-DIAMS ANATOMY 260
PG-DIAMS ANATOMY 261
The liver is divided into four portal sectors by the four main branches of the portal vein. These are right
lateral, right medial, left medial and left lateral (sometimes the term posterior is used in place of lateral
and anterior in place of medial).
The three main hepatic veins lie between these sectors as intersectorial veins. These intersectoral planes
are also called portal fissures (scissures). The fissures containing portal pedicles are called hepatic
fissures. Each sector is sub-divided into segments (usually two) based on their supply by tertiary divisions
of the vascular biliary sheaths.
Three major fissures, not visible on the surface, run through the liver parenchyma and harbour the three
main hepatic veins (main, left and right portal fissures). Three minor fissures are visible as physical
clefts of the liver surface (umbilical, venous and fissure of Gans).
Segment I (anatomical caudate lobe) lies posterior (dorsal) to segment IV with its left half directly
posterior to segments II and II and its medial half surrounded by major vascular branches. This segment
is a boundary line structure and receives dual artery, vein and duct supply. The Glissonian sheaths to
segment I arise from both right and left main sheaths: the segment therefore receives vessels
independently from the left and right portal veins and hepatic arteries. Caudate lobe is peculiar in the
finding that it drains independently into the inferior vena cava by multiple small branches and not into
major hepatic veins.. The bile ducts draining the segment are closely related to the confluence of the right
and left hepatic ducts.
Q. All is true about functional divisions of liver EXCEPT (AIIMS)
a) Based upon portal vein & hepatic vein
b) Divided into 8 segments
c) Three major & three minor fissures
d) 4 sectors
Liver is divided into eight (functional (surgical) segments according to Couinaud’s classification,
following hepatic veins and portal veins, and is further enhanced by following bile duct distribution.
Recently there was addition of a ninth segment, but most of the surgeons do not accept the new
addition for operative procedures.
The Bismuth system, which is a modified version of the Couinaud system, is the most commonly used
anatomic nomenclature system. In the Bismuth system, each segment has an independent vascular
supply, including arterial, portal, and venous supplies, as well as independent lymphatic and biliary
drainage.
PG-DIAMS ANATOMY 262
PG-DIAMS ANATOMY 263