CHEMISTRY PROJECT

ON

“TO FIND ADULTERANT IN

SOME COMMON MEDICINES”

2008-2009

SUBMITTED BY:
ABHILASH
XII-A
 ACKNOWLEDGEMENT

I would sincerely like to thank Mrs.REKHA

SACHDEVA For guiding me and supporting me
throughout this project.
 INDEX

AIM
MATERIAL REQUIRED
PURPOSE
THEORY
PROCEDURE
OBSERVATIONS
RESULT
PRECAUTIONS
BIBLIOGRAPHY
 CERTIFICATE

THIS IS TO CERTIFY THAT ABHILASH

GUPTA OF CLASS XII-A ,ROLL NO-1 HAS
WORKED UNDER MY SUPERVISION ON
THE PROJECT
“TO FIND ADULTERANT IN SOME
COMMON MEDICINES” AND HAS
COMPLETED TO MY TOTAL SATISFACTION

MRS.REKHA
 AIM

TO FIND ADULTERANT IN SOME

COMMON MEDICINES
 MATERIAL REQUIRED

Some medicines { local and standard}

Ethanol { C2H5OH }


Sodium Bicarbonate
Dilute Sulphuric Acid
Sodium Hydroxide
Copper Sulphate solution
Zinc powder
Nitric Acid
Silver Nitrate
Ferric Chloride
Potassium Hydroxide
 PURPOSE

IN DAILY NEWSPAPER MANY

CASES ARE SEEN ABOUT THE
DEATH AND SERIOUS REACTIONS
DUE TO ADULTERATED DRUGS . IF
WE ARE AWARE OF IT WE CAN
FIND OUT THE ADULTERATED
DRUGS I BECAME INTERESTED IN
THIS TOPIC AND THOUGHT TO
PREPARE A PROJECT ON
ADULTRATED MEDICINES.
 THEORY

SUB STANDARD DRUGS

WHICH CONTAIN MORE OR LESS QUALITY OF
THE MEDICAMENT ACCORDING TO STATED
AMOUNT.
SUBSTITUTED ON RESPECT OF
DISINTEGRATION .
SUBSTITUTED ON RESPEPTOF LABELING OF
PACKING .
ACCORDING TO THE GOVERNMENT
AGENCIES 14-20% AND ACCORDING
TO PRIVATE AGENCIES 20-30%
MEDICINES IN THE MARKET ARE
ADULTERATED OR DISBRANDED
 INTRODUCTION
CHEMICAL SUBSTANCES USED FOR
TREATEMENT OF DISEASES AND FOR
REDUCING THE SUFFERING FROM PAIN
ARE CALLED MEDICINES.
MEDICINES ARE ADULTRATED IF :
It contains in whole in part of any filthy ,putrid or
dec
omposed substances .
It has been prepared ,packed or stored under
unsanitary conditions thereby it may have
contaminated with filth or it may be injurious to
health .
In part of any poisonous or detritus substance
which may render the contents injurious to health .
It contains colour other than prescribed ones .

 DRUG TESTING
LABORATORIES

MANY CITIES HAVE DRUG TESTING

LABORATORIES LIKE IN
LUCKNOW,BHOPAL,CHANDIGARH,AH
MEDABAD ETC

In addition to abice central

government have two laboratories:

Central drug laboratory, kolkata .

Central Indian pharmacopacia laboratory,
Ghaziabad .
 PROCEDURE AND
OBSERVATION
MEDICIN TEST
E
30mg sample 30mg CO2 gas No If CO2 gas
+2 ml sample evolve reaction evolved,
C2H5OH+H2O+0. +2 ml d adulterant
5g NaHCO3 C2H5OH+ present
H2O+0.5g
NaHCO3 If yellow
10mg sample Dark solution is
+2ml HCL+ Yellow Violet formed,
heat 10mg solution Colour adulterant is
sample present
+2ml
HCL+ If violet
heat colour ppt is
Paracetamol Violet Brownish formed,
blue ppt. ppt adulterant is
present
50mg sample
+ 50ml H2O If brick red
+ 3 drops of colour is
Aspirin FeCl3 Brick red Red ppt formed,
ppt adulterant is
present
10mg
sample +
1-2 drop
 of FeCl3
+KOH

RESULT

THIS RESULT COMES OUT THAT SOME

OF THE LOCAL COMPANIES
ADULTERATE FOR THEIR PROFIT .
 PRECAUTIONS

1. TEST TUBES MUST BE CLEAN AND DRY.

2. CHEMICALS MUST BE HANDELED
CAREFULLY .
3.NOTICE THE CHANGES TAKING PLACE .
 BIBLIOGRAPHY
ABC CHEMISTRY-CLASS XIIth


WORLD -ENCYCLOPEDIA
 ADULTERATED MEDICINES
MEDICINES
ADULTERANT
1.Chloramphenical khariya
2.Tetracycline Turmeric powder
3.Analgin khariya
4.Anandker Colour Added
5.Septran khariya
6.B-Complex Sodium Benzoate
7.Glycerol Di-ethyl Glycol
8.Paracetamol Starch
9.A.P.C Paracetamol

The companies are trying to bring profit to themselves

without caring about the health of the citizens . They
try to bring popularity to their manufactured drugs
making use of different methods .

EXAMPLE- The medicine A.P.C. is taken while headache

or common cold .
It is manufactured by mixing aspirin, phanetin & caffeine. When
the harmful effects of phanetin was known, the government
banned the use of A.P.C. & the companies began to use
paracetamol instead of phenacetin.