Antibiotics B

1. All Cephalosporin Antibiotics (except Moxalactam)

2. All Erythromycin except ErythromycinEstolate
3. Azithromycin (Zithromax), but not Clarithromycin (see below)
4. All Penicillin Antibiotics
5. Clindamycin
6. Macrodantin (before 36 weeks)
7. Sulfa antibiotics (second trimester only)

Antibiotics c

1. Imipenem-Cilastin c
2. All Fluoroquinolone antibiotics (avoid in pregnancy due to cartilage damage risk)
3. Clarithromycin (Biaxin)
1. Contrast with Erythromycin and Azithromycin which are category B
4. Pediazole - not in Briggs (1998)
5. Sulfisoxazole - not in Briggs (1998)
6. Trimethoprim (Folic Acid antagonist)
1. May be used as part of Trimethoprim-Sulfamethoxazole (Bactrim, Septra) in second
trimester
7. Vancomycin
8. Chloramphenicol
9. Gentamicin

Antibiotics d

1. Amikacin (Class D per manufacturer)

2. Kanamycin
3. Streptomycin
4. Tobramycin (Class D per manufacturer)
5. Sulfa (Third Trimester)
6. All Tetracycline antibiotics
1. Tetracycline
2. Minocycline
3. Doxycycline
1. Does not appear to have same adverse effects as other Tetracyclines
2. May be considered in serious infections without good alternatives (e.g. Rocky
Mountain Spotted Fever)
7. Erythromycin Estolate (llosone)
1. Due to hepatotoxicity in pregnant women