Transform

<xsl:transform xmlns:xsl="http://www.w3.
org/1999/XSL/Transform"
xmlns:sap="http://www.sap.com/sapxsl" xmlns:mims="http://sapmims.com/mims"
version="1.0">
<xsl:param name="D2DSeverityFilter">^Caution^Minor^Moderate^Severe^</xsl:param>
<xsl:param name="D2HSeverityFilter">Êxtreme
Caution^Contraindication^Contraindicated^</xsl:param>
<xsl:param name="DocumentationFilter">^Not Established^Limited^Good^Well
Established^</xsl:param>
<xsl:param name="DuplicateTherapyFilter">^1^2^3^</xsl:param>
<xsl:param name="DuplicateIngredientFilter">^1^2^3^</xsl:param>
<xsl:param name="CriticalPrecautionFilter">^Never use this combination.Âvoid
combination.Ûse combination with extreme caution.Ûse combination with
caution.^Clinical significance not established; be alert for evidence of
interaction.^No action
required; be alert for evidence of interaction.Înteraction not clinically
significant.^</xsl:param>
<xsl:output indent="no" method="html" omit-xml-declaration="yes"/>


<xsl:key match="//Route/*[not(@Mirror='true' or
@Mirror='True')]/Route/ClassInteraction" name="D2DItems"
use="concat(PrescribingInteractionClass/@reference, '-',
InteractingClass/@reference)"/>
<xsl:key match="mims:d2d_sev_level" name="d2d_sev_level-lookup" use="@name"/>

<xsl:key match="mims:d2h_sev_level" name="d2h_sev_level-lookup" use="@name"/>
<xsl:key match="mims:d2l_sev_level" name="d2l_sev_level-lookup" use="@name"/>
<xsl:key match="mims:doc_level" name="doc_level-lookup" use="@name"/>
<xsl:key match="mims:preg_cat" name="preg_cat-lookup" use="@cat"/>
<xsl:key match="mims:preg_pic" name="preg_pic-lookup" use="@cat"/>
<xsl:variable name="d2d_sev_level-top"
select="document('')/*/mims:d2d_sev_levels"/>
<xsl:variable name="d2h_sev_level-top"
select="document('')/*/mims:d2h_sev_levels"/>
<xsl:variable name="d2l_sev_level-top"
select="document('')/*/mims:d2l_sev_levels"/>
<xsl:variable name="doc_level-top" select="document('')/*/mims:doc_levels"/>
<xsl:variable name="preg_cat-top" select="document('')/*/mims:preg_cats"/>
<xsl:variable name="preg_pic-top" select="document('')/*/mims:preg_pics"/>
<xsl:variable name="criticalPrecaution">./Precaution[Professional='Use
combination with extreme caution.']/Professional</xsl:variable>
<xsl:strip-space elements="*"/>
<xsl:template match="/">
<html>
<head>
<link href="css/redmond/jquery-ui-1.8.6.custom.css" rel="stylesheet"
type="text/css"/>
<link href="css/mims.css" rel="stylesheet" type="text/css"/>
<script src="scripts/jquery-1.4.4.min.js" type="text/javascript"/>
<script src="scripts/jquery-ui-1.8.6.custom.min.js"
type="text/javascript"/>
<xsl:choose>
<xsl:when test="count(//Interaction) > 0">
<script src="scripts/drugalert.js" type="text/javascript"/>
</xsl:when>
<xsl:otherwise>
<script src="scripts/monograph.js" type="text/javascript"/>
</xsl:otherwise>
</xsl:choose>
<style>
div.drug-label {
width: 90mm;
height: 35mm;
border: 1pt solid;
border-radius: 5pt;
padding: 5pt;
margin-bottom: 5pt;
}
.drug-label h4 {
font-size: 10pt;
font-weight: bold;
font-family: Arial;
margin: 2pt;
}
.drug-label p {
font-size: 8pt;
font-weight: normal;
font-family: Arial;
margin: -1pt 2pt 2pt 2pt;
}
.cals-details p {
margin-bottom: 0pt;
}
.cal-details li a {
text-decoration: none;
}
.cal-details strong { margin-right: 2pt; }
ol.allergy-list { padding-left: 1.33em; }

ol.allergy-list > li { padding-top: 0.5em; }
ol.allergy-list h4.subheading { margin-top: 0.2em; }
</style>
</head>
<body>
<xsl:apply-templates select="Result"/>
</body>
</html>
</xsl:template>
<xsl:template match="Result">
<xsl:apply-templates/>
</xsl:template>
<xsl:template match="Interaction">
<xsl:variable name="numDT"
select="count(//DuplicateTherapy/Warning[contains($DuplicateTherapyFilter,
concat('^',@Level, '^'))])"/>
<xsl:variable name="numHealth"
select="count(//HealthIssue/ClassInteraction[contains($D2HSeverityFilter,
concat('^',Severity/@name, '^')) and
contains($DocumentationFilter,
concat('^',Documentation/@name,
'^'))])

+
count(//HealthIssueCode/ClassInteraction[contains($D2HSeverityFilter,
concat('^',Severity/@name, '^')) and contains($DocumentationFilter,
concat('^',Documentation/@name, '^'))])"/>

<xsl:variable name="numAllergy" select="count(//*[Allergy])"/>
<xsl:variable name="numInteract" select="count(//Route/*[not(@Mirror='true' or
@Mirror='True')]/Route/ClassInteraction[contains($D2DSeverityFilter,
concat('^',Severity/@name,
'^'))
and
contains($DocumentationFilter,
concat('^',Documentation/@name
,
'^'))])"/>
<xsl:variable name="numDose" select="count(//DoseCheck/*/Warnings[count(*) >
0]) + count(//CombinedDoseCheck/*/Warnings[count(*) > 0])"/>
<xsl:variable name="numPreg" select="count(//*[Pregnancy/InteractionClass]) +
count(//*[WOCBA/InteractionClass])"/>
<xsl:variable name="numLact"
select="count(//Lactation/InteractionClass[count(*) > 0])"/>
<xsl:variable name="numDupIng"
select="count(//DuplicateIngredient/Warning[contains($DuplicateIngredientFilter,
concat('^',@Level, '^'))])"/>
<xsl:variable name="numLabels" select="count(//*[CautionaryLabels])"/>
<xsl:variable name="numTotal" select="$numDT + $numHealth + $numAllergy +
$numInteract + $numDose + $numPreg + $numLact + $numLabels + $numDupIng"/>

<xsl:choose>
<xsl:when test="$numTotal > 0">

<div class="tab-container" id="tabs">
<ul>
<xsl:if test="$numInteract > 0">
<li>
<a href="#tab-interaction">Drug Interaction (
<xsl:value-of select="$numInteract"/>
</a>
</li>
</xsl:if>
<xsl:if test="$numAllergy > 0">
<li>
<a href="#tab-allergy">Allergy (
<xsl:value-of select="$numAllergy"/>
)
</a>
</li>
</xsl:if>
<xsl:if test="$numHealth > 0">
<li>
<a href="#tab-health">Health Conditions (
<xsl:value-of select="$numHealth"/>
</a>
</li>
</xsl:if>
<xsl:if test="$numDT > 0">
<li>
<a href="#tab-dup">Duplicate Therapy (
<xsl:value-of select="$numDT"/>
</a>
</li>
</xsl:if>
<xsl:if test="$numDupIng > 0">
<li>
<a href="#tab-duping">Duplicate Ingredient (
<xsl:value-of select="$numDupIng"/>
</a>
</li>
</xsl:if>
<xsl:if test="$numDose > 0">
<li>
<a href="#tab-dose">Dose (
<xsl:value-of select="$numDose"/>
</a>
</li>
</xsl:if>
<xsl:if test="$numPreg > 0">
<li>
<a href="#tab-preg">Pregnancy (
<xsl:value-of select="$numPreg"/>
</a>
</li>
</xsl:if>
<xsl:if test="$numLact > 0">
<li>
<a href="#tab-lact">Lactation (
<xsl:value-of select="$numLact"/>
</a>
</li>
</xsl:if>
<xsl:if test="$numLabels > 0">
<li>
<a href="#tab-labels">Cautionary Labels (
<xsl:value-of select="$numLabels"/>
)
</a>
</li>
</xsl:if>
</ul>
<xsl:if test="$numDT > 0">

<div class="acc_container" id="tab-dup">
<div id="list_dup" style="height: 100%">
<xsl:apply-templates select="DuplicateTherapy"/>
</div>
</div>
</xsl:if>
<xsl:if test="$numDupIng > 0">

<div class="acc_container" id="tab-duping">
<div id="list_duping" style="height: 100%">
<xsl:apply-templates select="DuplicateIngredient"/>
</div>
</div>
</xsl:if>
<xsl:if test="$numInteract > 0">

<div class="acc_container" id="tab-interaction">
<div id="list_interactions">
<xsl:apply-templates select="(DrugItem|Product|GenericItem|
SpecificItem|GGPI|ActiveComposition|ActiveCompositionGroup)">
<xsl:with-param name="Mode" select="'drug'"/>
</xsl:apply-templates>
</div>
</div>
</xsl:if>
<xsl:if test="$numHealth > 0">

<div class="acc_container" id="tab-health">
<div id="list_health">
<xsl:with-param name="Mode" select="'health'"/>
</div>
</div>
</xsl:if>
<xsl:if test="$numAllergy > 0">

<div class="acc_container" id="tab-allergy">
<div id="list_allergies">
<xsl:with-param name="Mode" select="'allergy'"/>
</div>
</div>
</xsl:if>
<xsl:if test="$numDose > 0">

<div class="acc_container" id="tab-dose">
<div id="list_dose">
<xsl:apply-templates select="DoseCheck|CombinedDoseCheck"/>
</div>
</div>
</xsl:if>
<xsl:if test="$numPreg > 0">

<div class="acc_container" id="tab-preg">
<div id="list_preg">
<xsl:with-param name="Mode" select="'pregnancy'"/>
</div>
</div>
</xsl:if>
<xsl:if test="$numLact > 0">

<div class="acc_container" id="tab-lact">
<div id="list_lact">
<xsl:with-param name="Mode" select="'lactation'"/>
</div>
</div>
</xsl:if>
<xsl:if test="$numLabels > 0">

<div class="acc_container" id="tab-labels">
<div id="list_labels">
<xsl:apply-templates mode="label" select="(DrugItem|Product|
GenericItem|SpecificItem|GGPI|ActiveComposition|ActiveCompositionGroup)
[CautionaryLabels]"/>
</div>
</div>
</xsl:if>
</div>
</xsl:when>
<xsl:otherwise>
<h3 class="ui-state-default ui-widget-content ui-widget-header"
style="height:30px;text-align:center;padding-top: 10px">No results found. Absence
of interaction result should in no way be interpreted as safe. Clinical judgment
should be
exercised</h3>
</xsl:otherwise>
</xsl:choose>
</xsl:template>
<xsl:template match="DrugItem|Product|GenericItem|SpecificItem|GGPI|
ActiveComposition|ActiveCompositionGroup">
<xsl:param name="Mode"/>
<xsl:variable name="IntType1" select="name()"/>
<xsl:variable name="IntProd1" select="@name"/>
<xsl:variable name="IntRef1" select="@reference"/>
<xsl:choose>
<xsl:when test="$Mode='allergy' and Allergy">
<xsl:element name="div">
<xsl:variable name="DivId">a_
<xsl:value-of select="translate(@name, 'ABCDEFGHIJKLMNOPQRSTUVWXYZ

','abcdefghijklmnopqrstuvwxyz_')"/>
</xsl:variable>
<xsl:attribute name="id">
<xsl:value-of select="$DivId"/>
</xsl:attribute>
<h3>
<a href="#">Patient may be allergic to the prescribing item,
<xsl:value-of select="$IntProd1"/>
</a>
</h3>
<div>

<xsl:apply-templates select="Allergy">
<xsl:with-param name="IntProd1" select="$IntProd1"/>

</div>
</xsl:element>
</xsl:when>
<xsl:otherwise>
<xsl:for-each select="Route">
<xsl:variable name="IntRoute1" select="@name"/>
<xsl:if test="$Mode='pregnancy' and Pregnancy|WOCBA">
<xsl:variable name="DivId">pc_
<xsl:value-of select="translate($IntProd1,
'ABCDEFGHIJKLMNOPQRSTUVWXYZ ','abcdefghijklmnopqrstuvwxyz_')"/>
</xsl:variable>
<xsl:for-each select="WOCBA|Pregnancy">


<xsl:sort order="descending"
select="concat(Category[@Source='FDA']/@name,'-',InteractionClass/Molecule/@name)"/
>
<xsl:if test="position()=1">

</xsl:attribute>
<h3>
<a href="#">
<xsl:text> (</xsl:text>
<xsl:value-of select="InteractionClass/Molecule/@name"/>
<xsl:text>/</xsl:text>
<xsl:value-of select="../@name"/>
<xsl:text>) [</xsl:text>
<xsl:choose>
<xsl:when test="name()='WOCBA'">
<xsl:text>Women of Childbearing Age</xsl:text>
</xsl:when>
<xsl:when test="name()='Pregnancy'">
<xsl:value-of
select="../Pregnancy[position()=1]/Category/@Trimester"/>
<xsl:text> Trimester</xsl:text>
</xsl:when>
</xsl:choose>
<xsl:text>]</xsl:text>
</a>
</h3>
<div>
<xsl:apply-templates select="."/>
</div>
</xsl:element>
</xsl:if>
</xsl:for-each>
</xsl:if>
<xsl:if test="$Mode='lactation'">
<xsl:for-each select="Lactation">
<xsl:apply-templates select=".">
<xsl:with-param name="IntProd" select="$IntProd1"/>
<xsl:with-param name="Route" select="../@name"/>
</xsl:for-each>
</xsl:if>
<xsl:if test="$Mode='drug'">
<xsl:for-each select="(DrugItem|Product|GenericItem|SpecificItem|GGPI|
ActiveComposition|ActiveCompositionGroup)[not(@Mirror='true' or @Mirror='True')]">
<xsl:apply-templates select="Route">
<xsl:with-param name="IntProd2" select="@name"/>
<xsl:with-param name="IntRoute1" select="$IntRoute1"/>
</xsl:for-each>
</xsl:if>
<xsl:if test="$Mode='health'">
<xsl:apply-templates select="HealthIssueCode">
<xsl:apply-templates select="HealthIssue">
</xsl:if>
</xsl:for-each>
</xsl:otherwise>
</xsl:choose>
</xsl:template>
<xsl:template match="Route">
<xsl:param name="IntProd1"/>
<xsl:param name="IntRoute1"/>
<xsl:param name="Mode"/>
<xsl:variable name="IntRoute2" select="@name"/>
<xsl:for-each select="ClassInteraction[contains($D2DSeverityFilter,
concat('^',Documentation/@name, '^'))]">
<xsl:variable name="IntMol1"
select="PrescribingInteractionClass/PrescribingMolecule/@name"/>
<xsl:variable name="IntMol2" select="InteractionClass/Molecule/@name"/>
<xsl:variable name="DivId">i_
<xsl:value-of select="Severity/@ranking"/>
<xsl:value-of select="translate($IntMol1,
'ABCDEFGHIJKLMNOPQRSTUVWXYZ .','abcdefghijklmnopqrstuvwxyz__')"/>
'ABCDEFGHIJKLMNOPQRSTUVWXYZ
.','abcdefghijklmnopqrstuvwxyz__')"/>
</xsl:variable>
</xsl:attribute>
<h3>
<a href="#">
<xsl:call-template name="SeverityColor">
<xsl:with-param name="SeverityLevel" select="Severity/@ranking"/>
</xsl:call-template>

(
<xsl:value-of select="$IntMol1"/>
<xsl:value-of select="$IntRoute1"/>
<xsl:text> vs </xsl:text>
<xsl:value-of select="$IntRoute2"/>
<xsl:call-template name="ShowCriticalPrecaution">
<xsl:with-param name="PrecautionText"
select="./Precaution[contains($CriticalPrecautionFilter,concat('^',Professional/tex
t(),'^'))]/Professional"/>
</a>
</h3>
<div>
<h4 class="subheading">Interaction Effect</h4>
<p>
<xsl:text> </xsl:text>
<xsl:choose>
<xsl:when test="normalize-space(Observation/Abbreviated)">
<xsl:value-of select="Observation/Abbreviated"/>
</xsl:when>
<xsl:when test="normalize-space(Observation/Professional)">
<xsl:value-of select="Observation/Professional"/>
</xsl:when>
</xsl:choose>
</p>
<xsl:call-template name="d2dSeverity">
<xsl:with-param name="Severity" select="Severity/@name"/>
<xsl:call-template name="docLevel">
<xsl:with-param name="DocLevel" select="Documentation/@name"/>


<xsl:element name="button">
<xsl:attribute name="name">_ref</xsl:attribute>
<xsl:attribute name="id">_br_
</xsl:attribute>
<xsl:attribute name="class">read-more</xsl:attribute>
<xsl:text>Read more </xsl:text>
</xsl:element>
<xsl:attribute name="id">r_
</xsl:attribute>
<xsl:attribute name="style">display: none</xsl:attribute>
<h4 class="subheading">Probable Mechanism</h4>

<xsl:choose>
<xsl:when test="normalize-space(Interaction/Abbreviated)">
<xsl:value-of select="Interaction/Abbreviated"/>
</xsl:when>
<xsl:when test="normalize-space(Interaction/Professional)">
<xsl:value-of select="Interaction/Professional"/>
</xsl:when>
</xsl:choose>
<h4 class="subheading">Actions to be taken</h4>
<ol>
<xsl:apply-templates select="Precaution"/>
</ol>
<xsl:apply-templates select="References">
<xsl:with-param name="DivId" select="$DivId"/>
</xsl:element>
</div>
</xsl:element>
</xsl:for-each>
</xsl:template>
<xsl:template name="ShowCriticalPrecaution">
<xsl:param name="PrecautionText"/>
<xsl:if test="normalize-space($PrecautionText)">
<xsl:text> [</xsl:text>
<xsl:value-of select="$PrecautionText"/>
<xsl:text>]</xsl:text>
</xsl:if>
</xsl:template>
<xsl:template match="WOCBA|Pregnancy">
<xsl:variable name="PCAT" select="Category[@Source='FDA']/@name"/>
<xsl:if test="normalize-space($PCAT)">
<h4 class="subheading">FDA Category
<xsl:element name="img">
<xsl:attribute name="src">
<xsl:apply-templates select="$preg_pic-top">
<xsl:with-param name="Source" select="'FDA'"/>
<xsl:with-param name="Cat" select="$PCAT"/>
</xsl:attribute>
</xsl:element>
</h4>
<p>
<xsl:apply-templates select="$preg_cat-top">
<xsl:with-param name="Source" select="'FDA'"/>
<xsl:with-param name="Cat" select="$PCAT"/>
</p>
</xsl:if>
<xsl:if test="count(Category[@Source='MIMS']) > 0">
<h4 class="subheading">MIMS Notes</h4>
<p>
<xsl:value-of select="Category[@Source='MIMS']/Comment"/>
</p>
</xsl:if>
</xsl:template>
<xsl:template match="Lactation">
<xsl:param name="IntProd"/>
<xsl:param name="Route"/>
<xsl:variable name="DivId">la_
<xsl:value-of select="translate($IntProd, 'ABCDEFGHIJKLMNOPQRSTUVWXYZ

</xsl:variable>
</xsl:attribute>
<h3>
<a href="#">
<xsl:value-of select="$IntProd"/>
</a>
</h3>
<div>
<xsl:call-template name="d2lSeverity">
<xsl:value-of select="Comment"/>
</div>
</xsl:element>
</xsl:template>
<xsl:template match="HealthIssueCode">
<xsl:variable name="IntHealthCode" select="@code"/>
<xsl:variable name="IntHealthCodeType" select="@codeType"/>
<xsl:variable name="IntHealthCodeDesc" select="@name"/>
<xsl:for-each select="ClassInteraction[contains($D2HSeverityFilter,
<xsl:value-of
select="translate($IntHealthCode,
'ABCDEFGHIJKLMNOPQRSTUVWXYZ .','abcdefghijklm
nopqrstuvwxyz__')"/>
</xsl:variable>
</xsl:attribute>
<h3>
<a href="#">

<xsl:with-param name="SeverityLevel"
select="translate(Severity/@ranking, '123', '135')"/>
<xsl:value-of select="$IntHealthCode"/>
<xsl:value-of select="$IntHealthCodeDesc"/>
</a>
</h3>
<div>
<xsl:call-template name="d2hSeverity">

</xsl:attribute>
<xsl:text>Read more</xsl:text>
</xsl:element>
</xsl:attribute>

<xsl:choose>
</xsl:when>
</xsl:when>
</xsl:choose>
</xsl:element>
</div>
</xsl:element>
</xsl:for-each>
</xsl:template>
<xsl:template match="HealthIssue">
<xsl:variable name="IntHealthIssueName" select="@name"/>
<xsl:variable name="IntHealthCodeType" select="@codeType"/>
<xsl:for-each select="ClassInteraction[contains($D2HSeverityFilter,
_
<xsl:value-of
select="translate($IntHealthIssueName,
'ABCDEFGHIJKLMNOPQRSTUVWXYZ .','abcdefgh
ijklmnopqrstuvwxyz__')"/>
</xsl:variable>
</xsl:attribute>
<h3>
<a href="#">
<xsl:with-param name="SeverityLevel"
select="translate(Severity/@ranking, '123', '135')"/>
<xsl:value-of select="$IntHealthIssueName"/>
</a>
</h3>
<div>
<xsl:call-template name="d2hSeverity">
</xsl:attribute>
<xsl:text>Read more</xsl:text>
</xsl:element>
</xsl:attribute>

<xsl:choose>
</xsl:when>
</xsl:when>
</xsl:choose>
</xsl:element>
</div>
</xsl:element>
</xsl:for-each>
</xsl:template>
<xsl:template match="Allergy">
<div>
<h4 class="subheading">Allergy history:</h4>
<ol class="allergy-list">
<xsl:for-each select="*">
<xsl:choose>
<xsl:when test="name()='CrossSensitive'">
<xsl:apply-templates select=".">
</xsl:when>
<xsl:when test="CrossSensitive">
<xsl:apply-templates select="CrossSensitive">
</xsl:when>
<xsl:otherwise>
<li>The patient has a known history of allergic reaction to
<xsl:value-of select="name()"/>
<xsl:value-of select="@name"/>
.
<ul class="no-bullet-no-indent">
<xsl:choose>
<xsl:when test="name()='Molecule' and
.//PrescribingMolecule/@name!=@name">
<li>
contains
<xsl:value-of select=".//PrescribingMolecule/@name"/>
, which belongs to the same substance class as
</li>
</xsl:when>
<xsl:when test="name()='Molecule' and
.//PrescribingMolecule/@name=@name">
<li>
contains
</li>
</xsl:when>
<xsl:when test="name()='SubstanceClass'">
<li>
contains
, which belongs to that same substance class.
</li>
</xsl:when>
</xsl:choose>
</ul>
</li>
</xsl:otherwise>
</xsl:choose>
</xsl:for-each>
</ol>
</div>
</xsl:template>
<xsl:template match="CrossSensitive">
<xsl:variable name="DivId">c_
<xsl:value-of select="translate($IntProd1, 'ABCDEFGHIJKLMNOPQRSTUVWXYZ

</xsl:variable>
<xsl:variable name="AllergenType">
<xsl:choose>
<xsl:when test="name(..) = 'Allergy'">SubstanceClass</xsl:when>
<xsl:otherwise>
<xsl:value-of select="name(..)"/>
</xsl:otherwise>
</xsl:choose>
</xsl:variable>
<xsl:variable name="AllergenName">
<xsl:choose>
<xsl:when test="name(..) = 'Allergy'">
<xsl:value-of select=".//AllergySubstanceClass/@name"/>
</xsl:when>
<xsl:otherwise>
</xsl:otherwise>
</xsl:choose>
</xsl:variable>
<li>The patient has a known history of allergic reaction to
<xsl:value-of select="$AllergenType"/>
,
<em>
<xsl:value-of select="$AllergenName"/>
</em>
<ul class="no-bullet-no-indent">
<li>
<em>
</em>
contains
<em>
</em>
, which is cross-sensitive to
<em>
<xsl:value-of select="$AllergenName"/>
</em>
</li>
</ul>
</li>
</xsl:template>
<xsl:template match="DoseCheck|CombinedDoseCheck">
<xsl:for-each select="*[count(Warnings) > 0]">
<xsl:variable name="IntProd" select="@name"/>
<xsl:variable name="DivId">dc_
<xsl:value-of select="translate($IntProd, 'ABCDEFGHIJKLMNOPQRSTUVWXYZ

</xsl:variable>
</xsl:attribute>
<h3>
<a href="#">
<xsl:if test="name(..)='CombinedDoseCheck'">
<xsl:text>[Combined Dose Check] </xsl:text>
</xsl:if>
<xsl:value-of select="$IntProd"/>
</a>
</h3>
<div>
<xsl:for-each select="Warnings/Warning">
<div class="ui-widget">
<div class="ui-state-default ui-corner-all warning-bar">
<p>
<span class="ui-icon ui-icon-alert"/>
<xsl:choose>
<xsl:when test="normalize-space(text())">
<xsl:value-of select="text()"/>
</xsl:when>
<xsl:otherwise>
<xsl:value-of select="Message"/>
</xsl:otherwise>
</xsl:choose>
<xsl:if test="ValidRoutes|ValidForms|ValidIndications">
<ul>
<xsl:for-each select="*/*">
<li>
<xsl:choose>
<xsl:when test="@name">
</xsl:when>
<xsl:otherwise>
<xsl:value-of select="text()"/>
</xsl:otherwise>
</xsl:choose>
</li>
</xsl:for-each>
</ul>
</xsl:if>
</p>
</div>
</div>
</xsl:for-each>
</div>
</xsl:element>
</xsl:for-each>
<xsl:apply-templates select="CombinedDoseCheck"/>
</xsl:template>
<xsl:template match="Precaution">
<li>
<xsl:choose>
<xsl:when test="normalize-space(./Abbreviated)">
<xsl:value-of select="./Abbreviated"/>
</xsl:when>
<xsl:when test="normalize-space(./Professional)">
<xsl:value-of select="./Professional"/>
</xsl:when>
</xsl:choose>
</li>
</xsl:template>
<xsl:template match="DuplicateTherapy">
<xsl:for-each select="./Warning[contains($DuplicateTherapyFilter,
concat('^',@Level, '^'))]">
<xsl:variable name="DuplicateLevel" select="translate(@Level, '123',
'531')"/>
<xsl:for-each select="./Duplicate">

<xsl:variable name="ATCCode"
select="translate(@ATCCode,'abcdefghijklmnopqrstuvwxyz','ABCDEFGHIJKLMNOPQRSTUVWXYZ
')"/>
<xsl:variable name="DupPair">
<xsl:for-each select="./*">
<xsl:variable name="type" select="name()"/>
<xsl:variable name="ref" select="@reference"/>

<em>
<xsl:value-of select="/Result/Interaction/*[@reference=$ref]/@name"/>
</em>
<xsl:text> and </xsl:text>
</xsl:if>
</xsl:for-each>
</xsl:variable>
<xsl:attribute name="id">d_
<xsl:value-of select="$DuplicateLevel"/>
<xsl:value-of select="translate($DupPair, 'ABCDEFGHIJKLMNOPQRSTUVWXYZ

_
<xsl:value-of select="translate($DupPair,
'ABCDEFGHIJKLMNOPQRSTUVWXYZ
</xsl:attribute>
<h3>
<a>
<xsl:with-param name="SeverityLevel" select="$DuplicateLevel"/>
<xsl:value-of select="$DupPair"/>
[ATC Code:
<xsl:value-of select="$ATCCode"/>
</a>
</h3>
</xsl:element>
</xsl:for-each>
</xsl:for-each>
</xsl:template>
<xsl:template match="DuplicateIngredient">
<xsl:for-each select="./Warning[contains($DuplicateIngredientFilter,
concat('^',@Level, '^'))]">
<xsl:variable name="DuplicateLevel" select="translate(@Level, '123',
'531')"/>
<xsl:for-each select="./Molecule">
<xsl:variable name="DupPair">
<xsl:for-each select="./*">
<xsl:variable name="type" select="name()"/>
<xsl:variable name="ref" select="@reference"/>

<em>
<xsl:value-of select="/Result/Interaction/*[@reference=$ref]/@name"/>
</em>
<xsl:text> and </xsl:text>
</xsl:if>
</xsl:for-each>
</xsl:variable>
<xsl:attribute name="id">d_
<xsl:value-of select="$DuplicateLevel"/>


</xsl:attribute>
<h3>
<a>
<xsl:with-param name="SeverityLevel" select="$DuplicateLevel"/>
<xsl:value-of select="$DupPair"/>
</a>
</h3>
</xsl:element>
</xsl:for-each>
</xsl:for-each>
</xsl:template>
<xsl:template match="References">
<xsl:param name="DivId"/>
<h4 class="subheading">References</h4>
<ul>
<xsl:apply-templates select="JournalReference"/>
<xsl:apply-templates select="ElectronicReference"/>
<xsl:apply-templates select="BookReference"/>
<xsl:apply-templates select="WebReference"/>
</ul>
</xsl:template>

<xsl:template match="JournalReference">
<li>
<xsl:value-of disable-output-escaping="yes" select="Author"/>
<xsl:text>. </xsl:text>
<xsl:value-of select="Title"/>
<i>
<xsl:value-of select="Journal"/>
</i>
<xsl:value-of select="Year"/>
<xsl:text>; </xsl:text>
<xsl:value-of select="Volume"/>
<xsl:if test="string-length(Part) > 0">
<xsl:text>(</xsl:text>
<xsl:value-of select="Part"/>
<xsl:text>)</xsl:text>
</xsl:if>
<xsl:text>:</xsl:text>
<xsl:value-of select="Page"/>
</li>
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<xsl:template match="ElectronicReference">
<li>
<xsl:value-of select="RefTitle"/>
<xsl:value-of select="SystemName"/>
<xsl:value-of disable-output-escaping="yes" select="SystemAuthor"/>
<xsl:value-of select="SystemManf"/>
<xsl:value-of select="SystemManfLoc"/>
<xsl:value-of select="SystemManfCountry"/>
<xsl:text> Available from URL: </xsl:text>
<a>
<xsl:attribute name="href">
<xsl:value-of select="URL"/>
</xsl:attribute>
</a>
<xsl:text>. (Accessed on </xsl:text>
<xsl:value-of select="Date"/>
</li>
</xsl:template>
<xsl:template match="BookReference">
<li>
<xsl:value-of disable-output-escaping="yes" select="Author"/>
<xsl:value-of select="ChapterTitle"/>
<xsl:text>. In: </xsl:text>
<xsl:value-of select="Edition"/>
<xsl:text> ed. </xsl:text>
<xsl:if test="string-length(Volume) > 0">
<xsl:value-of select="Volume"/>
</xsl:if>
<xsl:value-of select="PublishLoc"/>
<xsl:text>: </xsl:text>
<xsl:value-of select="Publisher"/>
<xsl:value-of select="Year"/>
<xsl:value-of select="Page"/>
</li>
</xsl:template>
<xsl:template match="WebReference">
<li>
<i>
<xsl:value-of select="Site"/>
</i>
<xsl:text> URL: </xsl:text>
<a>
</xsl:attribute>
</a>
<xsl:text>. (Accessed on </xsl:text>
<xsl:value-of select="Date"/>
</li>
</xsl:template>
<xsl:template name="SeverityColor">
<xsl:param name="SeverityLevel"/>
<table class="severity">
<tr>
<xsl:element name="td">
<xsl:attribute name="class">
<xsl:value-of select="concat('severity', $SeverityLevel)"/>
</xsl:attribute>
</xsl:element>
</tr>
</table>
</xsl:template>
<xsl:template name="d2dSeverity">
<xsl:param name="Severity"/>
<h4 class="subheading">Severity Level</h4>
<p>
<em>
<xsl:value-of select="$Severity"/>
</em>
<xsl:text> - </xsl:text>
<xsl:apply-templates select="$d2d_sev_level-top">
<xsl:with-param name="SeverityLevel" select="$Severity"/>
</p>
</xsl:template>
<xsl:template match="mims:d2d_sev_levels">
<xsl:value-of select="key('d2d_sev_level-lookup', $SeverityLevel)/text()"/>
</xsl:template>
<xsl:template name="d2hSeverity">
<p>
<em>
</em>
<xsl:apply-templates select="$d2h_sev_level-top">
</p>
</xsl:template>
<xsl:template match="mims:d2l_sev_levels">
<xsl:value-of select="key('d2l_sev_level-lookup', $SeverityLevel)/text()"/>
</xsl:template>
<xsl:template name="d2lSeverity">
<em>
</em>
<xsl:apply-templates select="$d2l_sev_level-top">
</xsl:template>
<xsl:template match="mims:d2h_sev_levels">
<xsl:value-of select="key('d2h_sev_level-lookup', $SeverityLevel)/text()"/>
</xsl:template>
<xsl:template name="docLevel">
<xsl:param name="DocLevel"/>
<h4 class="subheading">Documentation Level</h4>
<p>
<em>
<xsl:value-of select="$DocLevel"/>
</em>
<xsl:apply-templates select="$doc_level-top">
<xsl:with-param name="DocLevel" select="$DocLevel"/>
</p>
</xsl:template>
<xsl:template match="mims:doc_levels">
<xsl:param name="DocLevel"/>
<xsl:value-of select="key('doc_level-lookup', $DocLevel)/text()"/>
</xsl:template>
<xsl:template match="mims:preg_cats">
<xsl:param name="Source"/>
<xsl:param name="Cat"/>
<xsl:value-of select="key('preg_cat-lookup', concat($Source, '!',
$Cat))/text()"/>
</xsl:template>
<xsl:template match="mims:preg_pics">
<xsl:param name="Source"/>
<xsl:param name="Cat"/>
<xsl:value-of select="key('preg_pic-lookup', concat($Source, '!',
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</xsl:template>


<mims:d2d_sev_levels>
<mims:d2d_sev_level name="Caution">
The interaction may occur based on the mechanism of action of the co-administered
medicines. Be alert for increased or decreased effect, depending on the combination
of medicines.
</mims:d2d_sev_level>
<mims:d2d_sev_level name="Minor">
Clinical effects of the interaction are limited and may be bothersome but would not
usually require a major change to therapy. The patient
should be monitored for the possible manifestations of the interaction.
<mims:d2d_sev_level name="Moderate">
These medications may interact resulting in the potential deterioration of the
patient's condition. The patient should be monitored for the possible
manifestations of the interaction. Medical intervention or a change in therapy may
be required.
<mims:d2d_sev_level name="Severe">
The interaction between these medications may be life-threatening or may cause
permanent damage. These medications are not usually used concurrently; medical
intervention may be required.
</mims:d2d_sev_levels>
<mims:d2h_sev_levels>
<mims:d2h_sev_level name="Contraindicated">
Absolute contraindication; the use of the drug is completely inadvisable and should
be avoided.</mims:d2h_sev_level>
<mims:d2h_sev_level name="Contraindication">
Absolute contraindication; the use of the drug is completely inadvisable and should
be avoided.</mims:d2h_sev_level>
<mims:d2h_sev_level name="Extreme Caution">
Use of the drug is not recommended and the patient has a higher risk of developing
adverse effects or exacerbation of their existing health condition, however, use is
still possible and the risk may be outweighed by other
considerations.</mims:d2h_sev_level>
</mims:d2h_sev_levels>
<mims:d2l_sev_levels>
<mims:d2l_sev_level name="Contraindicated">
Human experience may or may not be available but these drugs can have severe
toxicity to a nursing infant. The drug should not be given to a nursing mother.
These drugs also include those that are indicated in conditions where lactation is
a
contraindication.</mims:d2l_sev_level>
<mims:d2l_sev_level name="Contraindication">
Human experience may or may not be available but these drugs can have severe
toxicity to a nursing infant. The drug should not be given to a nursing mother.
These drugs also include those that are indicated in conditions where lactation is
a
contraindication.</mims:d2l_sev_level>
<mims:d2l_sev_level name="Avoid if possible">
These drugs have been reported to cause clinically significant side effects to a
nursing infant, and/or existing animal data suggest significant risks to a nursing
infant. These agents may also inhibit lactation or may harm the mother. If use
during
breastfeeding is unavoidable, monitoring is needed for possible toxicity to either
mother or infant.
</mims:d2l_sev_level>
<mims:d2l_sev_level name="Caution">
These drugs may theoretically cause side effects to a nursing infant but have
either not been observed to do so or have only occasionally caused mild side
effects. These agents may be given to a lactating mother but monitoring is needed
for possible
toxicity to either mother or infant.</mims:d2l_sev_level>
</mims:d2l_sev_levels>
<mims:doc_levels>
<mims:doc_level name="Well Established">
There have been several published reports of this interaction. The pharmacological
explanation of why the interaction occurs is well documented and understood.There
are usually controlled studies that have established that the interaction exists.
</mims:doc_level>
<mims:doc_level name="Good">
Although controlled studies may not have been performed, several case reports have
been documented and other data strongly suggests this interaction exists.
</mims:doc_level>
<mims:doc_level name="Limited">
Few reports of this interaction exist. These few reports usually consist of limited
case reports where clinically sound justification of the interaction is found.
</mims:doc_level>
<mims:doc_level name="Not Established">
The interaction may have occurred with other medicines within the same class, or
there is a theoretical possibility that the interaction exists.
</mims:doc_level>
</mims:doc_levels>
<mims:preg_cats>
<mims:preg_cat cat="FDA!A">Adequate and well-controlled human studies have
failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and
there is no evidence of risk in later trimesters).</mims:preg_cat>
<mims:preg_cat cat="FDA!B">Animal reproduction studies have failed to
demonstrate a risk to the fetus and there are no adequate and well-controlled
studies in pregnant women OR Animal studies have shown an adverse effect, but
adequate and
well-controlled studies in pregnant women have failed to demonstrate a risk to the
fetus in any trimester.</mims:preg_cat>
<mims:preg_cat cat="FDA!C">Animal reproduction studies have shown an adverse
effect on the fetus and there are no adequate and well-controlled studies in
humans, but potential benefits may warrant use of the drug in pregnant women
despite potential
risks.</mims:preg_cat>
<mims:preg_cat cat="FDA!D">There is positive evidence of human fetal risk based
on adverse reaction data from investigational or marketing experience or studies in
humans, but potential benefits may warrant use of the drug in pregnant women
despite
potential risks.</mims:preg_cat>
<mims:preg_cat cat="FDA!X">Studies in animals or humans have demonstrated fetal
abnormalities and/or there is positive evidence of human fetal risk based on
adverse reaction data from investigational or marketing experience, and the risks
involved in
use of the drug in pregnant women clearly outweigh potential
benefits.</mims:preg_cat>
<mims:preg_cat cat="ADEC!A">Drugs which have been taken by a large number of

pregnant women and women of childbearing age without an increase in the frequency
of malformations or other direct or indirect harmful effects on the fetus having
been
observed.</mims:preg_cat>
<mims:preg_cat cat="ADEC!B1">Drugs which have been taken by only a limited
number of pregnant women and women of childbearing age, without an increase in the
frequency of malformation or other direct or indirect harmful effects on the human
fetus
having been observed.
Studies in animals have not shown evidence of an increased occurrence of fetal
damage.</mims:preg_cat>
fetus
Studies in animals are inadequate or may be lacking, but available data show no
evidence of an increased occurrence of fetal damage.</mims:preg_cat>
fetus
Studies in animals have shown evidence of an increased occurrence of fetal damage,
the significance of which is considered uncertain in humans.</mims:preg_cat>
<mims:preg_cat cat="ADEC!C">Drugs which, owing to their pharmaceutical effects,
have caused or may be suspected of causing, harmful effects on the human fetus or
neonate without causing malformations. These effects may be
reversible.</mims:preg_cat>
<mims:preg_cat cat="ADEC!D">Drugs which have caused, are suspected to have
caused or may be expected to cause, an increased incidence of human fetal
malformations or irreversible damage. These drugs may also have adverse
pharmacological
effects.</mims:preg_cat>
<mims:preg_cat cat="ADEC!X">Drugs that have such a high risk of causing
permanent damage to the fetus that they should NOT be used in pregnancy or when
there is a possibility of pregnancy.</mims:preg_cat>
</mims:preg_cats>
<mims:preg_pics>
<mims:preg_pic cat="FDA!A">images/cata.gif</mims:preg_pic>
<mims:preg_pic cat="FDA!B">images/catb.gif</mims:preg_pic>
<mims:preg_pic cat="FDA!C">images/catc.gif</mims:preg_pic>
<mims:preg_pic cat="FDA!D">images/catd.gif</mims:preg_pic>
<mims:preg_pic cat="FDA!X">images/catx.gif</mims:preg_pic>
</mims:preg_pics>
<xsl:template match="Content">
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<xsl:when test="count(*)=0">
<div class="ui-widget">
<div class="ui-state-default ui-corner-all warning-bar">
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No prescribing information available.
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<xsl:with-param name="SectionData" select="ATCDET"/>
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<xsl:with-param name="SectionData" select="FSTO"/>
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<xsl:with-param name="SectionData" select="FPP"/>
</table>
</xsl:template>
<xsl:template match="MONOGRAPH">
</h4>
<xsl:with-param name="SectionData" select="GENMONO"/>
<xsl:with-param name="SectionData" select="BI"/>
<xsl:with-param name="SectionData" select="GDOSE"/>
<xsl:with-param name="SectionName">Administration</xsl:with-param>
<xsl:with-param name="SectionData" select="GPPPA"/>
<xsl:with-param name="SectionData" select="GCI"/>
<xsl:with-param name="SectionName">Special precautions</xsl:with-param>
<xsl:with-param name="SectionData" select="GSP"/>
<xsl:with-param name="SectionName">Adverse reactions</xsl:with-param>
<xsl:with-param name="SectionData" select="GAR"/>
<xsl:with-param name="SectionName">Drug interactions</xsl:with-param>
<xsl:with-param name="SectionData" select="GDI"/>
<xsl:with-param name="SectionName">Mechanism of action</xsl:with-param>
<xsl:with-param name="SectionData" select="GACTION"/>
<xsl:with-param name="SectionName">Lab Interference</xsl:with-param>
<xsl:with-param name="SectionData" select="GLAB"/>
<xsl:with-param name="SectionName">Food Interaction</xsl:with-param>
<xsl:with-param name="SectionData" select="GFOOD"/>
<xsl:with-param name="SectionName">MIMS Class</xsl:with-param>
<xsl:with-param name="SectionData" select="translate(GCLS, '*', '')"/>
<xsl:with-param name="SectionData" select="GATC2"/>
<xsl:with-param name="SectionData" select="BPOI"/>
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<xsl:with-param name="SectionData" select="BPCAT"/>
</table>
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<xsl:param name="SectionName"/>
<xsl:param name="SectionData"/>
<xsl:if test="normalize-space($SectionData)">
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<xsl:value-of select="$SectionName"/>
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<xsl:value-of disable-output-escaping="yes" select="$SectionData"/>
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<xsl:template match="DrugItem|Product|GenericItem|SpecificItem|GGPI|
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<xsl:variable name="IntProd1" select="@name"/>
<xsl:variable name="IntRef1" select="@reference"/>
<div>
<h3>
<a href="#">
</a>
</h3>
<div>
<div class="drug-label">
<h4>
</h4>
<xsl:apply-templates select=".//CautionaryLabel"/>
</div>
<xsl:apply-templates mode="cals-details" select=".//CautionaryLabel"/>
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<xsl:template match="CautionaryLabel">
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<xsl:value-of select="Warning"/>
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<xsl:template match="CautionaryLabel" mode="cals-details">

<div class="cal-details">
<p>
<strong>
<xsl:value-of select="@type"/>
Warning:
</strong>
<xsl:value-of select="Warning"/>
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<xsl:if test="Description">
<p>
<strong>Explanation:</strong>
<xsl:value-of select="Description"/>
</p>
</xsl:if>
<xsl:apply-templates mode="cals" select="References"/>
<hr/>
</div>
</xsl:template>
<xsl:template match="References" mode="cals">

<h4 class="subheading">References</h4>
<ul>
<xsl:apply-templates mode="cals" select="Journal"/>
<xsl:apply-templates mode="cals" select="Website"/>
</ul>
</xsl:template>
<xsl:template match="Website|Journal" mode="cals">

<li>
<xsl:choose>
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<xsl:element name="a">
</xsl:attribute>
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</li>
</xsl:template>
</xsl:transform>

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<xsl:transform xmlns:xsl="http://www.w3.

<xsl:output indent="no" method="html" omit-xml-declaration="yes"/>

<xsl:key match="mims:d2d_sev_level" name="d2d_sev_level-lookup" use="@name"/>

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<h4 class="subheading">Probable Mechanism</h4>

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<h4 class="subheading">Probable Mechanism</h4>

<h4 class="subheading">Probable Mechanism</h4>

, which belongs to the same substance class as

, which belongs to that same substance class.

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<mims:preg_cat cat="ADEC!A">Drugs which have been taken by a large number of

No prescribing information available.

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