Correlation between Allergic Rhinitis and Otitis Media with Effusion

Mohammad Reza Sharifian1,MD; Mahmoud Mahmoudi2,MD; *Babak

Pourmomenarabi1,MD; Mohammad Reza Keramati3,MD

Iranian Journal of Otorhinolaryngology, Vol.31(4), Serial No.105, July 2019

CRITICAL APPRAISAL

General Description
1. Design : Case control study
2. Subject : 37 OME children as the case group and 52 children were
randomly chosen as the control group. These two groups were
enrolled between November 2015 – December 2016
3. Title : Interesting and straightforward
4. Authors : Clearly written constitution and there is a
correspondence address.
5. Abstract : Clear and appropriate rules.
6. Introduction : Clearly explain the background, research objectives and
the importance of research.

Level of Evidence
Level 4 (Case control studies)

P-I-C-O Analysis
1. Population : A case control study that include 11.283 participants consist
of 18 years old and older who had undergone laryngoscopic and nasal
endoscopic examination from 2010 to 2012, the data is taken from fifth
edition of the Korean National Health and Nutrition Examintaion Survey
2. Intervention : Quistionnaires and physical examination (laryngoscopic and
nasal endoscopic)

1
 3. Comparison : No comparison.

4. Outcome : Chronic laryngitis diagnosed by laryngoscopic eamination

and allergic cause of laryngitis determined by specific serum
immunoglobulin E tests

V-I-A Analysis
1. Validity :
Recruitment and randomize method has been explained in this study, include
the details of questionnaire and result of laryngoscopic and endoscopic
examination

2. Importance :
This study aims to estimate association between prevalence of chronic
laryngitis with sinonasal symptoms and endoscopic findings
3. Applicability :
The research may be valuable to give some informations about diagnosing
chronic laryngitis by its sinonasal symptoms and endoscopic findings and
also laryngoscopic findings

2
Cross sectional study worksheet

Appraisal questions Yes Can’t tell No

✔
1. Did the study address a clearly focused
question / issue?
2. Is the research method (study design) ✔
appropriate for answering the research
question?
✔
3. Is the method of selection of the subjects
(employees, teams, divisions, organizations)
clearly described?
✔
4. Could the way the sample was obtained
introduce (selection) bias?
✔
5. Was the sample of subjects representative
with regard to the population to which the
findings will be referred?
✔
6. Was the sample size based on pre-study
considerations of statistical power?
✔
7. Was a satisfactory response rate achieved?
✔
8. Are the measurements (questionnaires) likely
to be valid and reliable?
✔
9. Was the statistical significance assessed?
✔
10. Are confidence intervals given for the main
results?
11. Could there be confounding factors that ✔
haven’t been accounted for?
✔
12. Can the results be applied to your
organization?