Republic of the Philippines

Department of Education
Region VII, Central Visayas
DIVISION OF LAPU-LAPU CITY
B.M. Dimataga St., Lapu-Lapu City

LESSON PLAN IN SCIENCE

Name Beverly S. Baguio Date:

Section & Time Day:

Learning Level 10
Competency Explain how mutations may cause changes in the structure and function of a
protein. (S10LT- IIIe-38) Quarter 3rd

Learning Knowledge: Differentiate the kinds of chromosomal mutations. Week 6

Objectives Skills: Illustrate the kinds of chromosomal mutations. No.
Attitudes: Visualize positively the chromosomal mutations
Day 2
TOPIC Mutation: Changes in the Genetic Code Duration:

Resources Grade 10 Science Teacher’s Guide and Science Textbooks

Needed

PROCEDURE:
Element of
Suggested Activities
the Plan
Engagement 1. Prayer
( Awareness) 2. Checking of attendance
3. Recapitulation.
4. Review of the classroom house rules.
5. Distribution of the activity sheets
Exploration Students perform Activity 6: Chromie Change
(Activity) ( localized) teacher can use modeling clay of different color or gelatin of varied colors
Explanation 1. What is mutation?
( Analysis & Ans. Mutation is any change in the DNA sequence.
Abstraction) 2. What are the two types of mutation?
Ans. These are the gene mutation and chromosomal mutation.
3. How does gene mutation differ from chromosomal mutation?
Ans: Gene mutation is a permanent change in the DNA sequence that makes up a gene while chromosomal
mutation occurs at the chromosome level resulting in gene deletion, duplication or rearrangement that may
occur during the cell cycle and meiosis.
4. What are some genetic disorders in humans?
Ans: Cri du chat, Down’s syndrome, Edward’s syndrome, Jacobsen syndrome, Klinefelter’s syndrome
and Turner’s syndrome.
5. It is a genetic disorder due to extra copy of chromosome 21.
Ans. Down syndrome
6. A genetic disorder due to trisomy of chromosome 18.
Ans: Edward’s syndrome

Elaboration 1. Mutation is any change in the DNA sequence.

(Application) 2. Gene mutation is a permanent change in the DNA sequence that makes up a gene while chromosomal
mutation occurs at the chromosome level resulting in gene deletion, duplication or rearrangement that may
occur during the cell cycle and meiosis.
Evaluation 1. What is mutation?
(Assessment) Ans. Mutation is any change in the DNA sequence.
2. What are the two types of mutation?
Ans. These are the gene mutation and chromosomal mutation.
3. How does gene mutation differ from chromosomal mutation?
Ans: Gene mutation is a permanent change in the DNA sequence that makes up a gene while chromosomal
mutation occurs at the chromosome level resulting in gene deletion, duplication or rearrangement that may
occur during the cell cycle and meiosis.
 4. What are some genetic disorders in humans?
Ans: Cri du chat, Down’s syndrome, Edward’s syndrome, Jacobsen syndrome, Klinefelter’s syndrome
and Turner’s syndrome.
5. It is a genetic disorder due to extra copy of chromosome 21.
Ans. Down syndrome
6. A genetic disorder due to trisomy of chromosome 18.
Ans: Edward’s syndrome

Assignment What is the significance of knowing the effects of mutation in the genes and chromosomes?
Answers may vary
The students answer this question:
Is mutation bad? Why? Why not?
Remarks