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CHEMISTRY DEPARTMENT
JANUARY, 2005.
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1.0 INTRODUCTION
1.1 BACKGROUND
The Chemistry Department at UDSM was established in 1965 under the Faculty of
Science and teaching, research and consultancy. It is the only unit which provides
full time tertiary education in chemistry in Tanzania. In addition, the Department
plays a major role in all chemistry related training activities in the country. Chemistry
graduates of UDSM are employed in:
(1) the education sector, as teachers in secondary and high schools as well as in
teacher training and technical colleges,
(2) research in analytical and processing laboratories of various industries and
government institutions, and
(3) the private sector especially in the fields of food processing, petroleum
processing, textile manufacture, agriculture, mining and mineral processing,
pulp and paper industries and in the pharmaceutical industries.
Chemically related industries in Tanzania are mostly concerned with, among others,
the processing of agricultural products and agricultural pest control agents, food,
textiles, plastics; as well as oil refining and formulation, mining, construction, fertiliser
manufacture, brewing and bottling, pharmaceuticals, confectionery, pulp and paper,
paints manufacture, fermentation, metal works, and environmental management and
impact assessment. Institutes in Tanzania dealing with various chemical activities,
include biomedical research (The National Institute for Medical Research), agriculture
and livestock (Ministry of Agriculture and Livestock Development), pest control
(Tropical Pesticides Research Institute), forensic chemistry (the Government Chemist
Laboratory Agency) and industrial research (Tanzania Industrial Research and
Development Organisation). Other organisations dealing with chemistry related
activities include the Tanzania Bureau of Standards, Tanzania Industrial Studies and
Consultancy Organisation and the National Environmental Management Council. All
these industries and research institutions require appropriately trained chemists.
The recent liberalisation of the Tanzanian economy has stimulated industrial and
social investments by the private sector, and this has increased the demand for
chemistry graduates with B.Sc., M.Sc. and Ph.D. qualifications.
The aforementioned coincides with the expressed desire of the mission and vision of
the University of Dar es Salaam (UDSM) as stipulated in its Corporate Strategic
Plan. The plan ascertains that the University of Dar es Salaam has the following
basic inter-related purposes:
• To be directly engaged in the creation, transmission and evaluation of
knowledge in the pursuit of excellence in academic scholarship and intellectual
inquiry through teaching, research and provision of advisory and public service.
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All the undergraduate courses offered by the Department have recently been reviewed
to improve their relevance to Tanzania's needs and to include current scientific
advancements. However, the subject has remained as a single major, a situation,
which has, in recent years limited the effectiveness of the current Chemistry graduates
outside the education sector. In order to cope with this current and projected demand,
the Chemistry Department is proposing a new BSc (Chemistry) degree program.
The Tanzania Development Vision 2025 (Vision 2025) paper and the Poverty
Reduction Strategy Paper (PRSP) documents highlight the government's
commitment towards the provision of relevant education to Tanzanians at all levels.
Thus, technical training, tertiary education and science and technology are expected
to play a leading role in the attainment of the development of the country. Vision
2025 and the PRSP have, as their targets, the creation of a well-educated nation
and the development and improvement of science and technology education at all
levels. The BSc (Chem.) programme is expected to contribute towards this goal by
increasing the number and quality of chemistry human resources in Tanzania.
The main objective of the establishment of the Department of Chemistry since its
inception has been to train the work force of teachers for our secondary schools.
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The Faculty of Science is running a BSc (General) programme in which, during the
three years of study students major in two science subjects. Those majoring in
chemistry follow the same courses as BSc (Education) students. While the drive to
serve the education sector is still valid to date, new areas have evolved into which
chemistry graduates can be absorbed. These include the chemical based industries
as well as research institutions now scattered across the country. The liberalisation
of the Tanzanian economy, stimulated by the high industrial and social investments
by the private sector, has put a new need for chemistry University graduates to be
more knowledgeable, capable of self-employment as well as become managers of
their own entrepreneurs. There is also an increasing need for various private and
public institutions to produce competitive products and therefore an increasing
demand for appropriately trained chemists and laboratory managers. The proposed
BSc in chemistry curriculum, therefore, will address the shortcomings that are
inherent in the current curriculum.
The department is currently offering courses that are part of the BSc (Ed), BEd (Sc),
BEd (PESC), BSc (Gen) BSc (Geol), BSc. (MPE) and BSc. (CPE) degree
programmes. Apart from the undergraduate degree programmes the department
also offers advanced studies leading to awards of Master of Science and Doctor of
Philosophy in various fields of specialisation, including, natural products, materials
science, pesticides, environmental chemistry and theoretical chemistry.
Thermal Analysis
Natural Products
From the survey results (APPENDIX III) the following observation are apparent:
(i) The status of chemistry graduates nation-wide:
• 76% of the institutions surveyed have employed UDSM chemistry graduates.
• 80% of the institutions that have not employed UDSM chemistry graduates
anticipate employing them in the near future. The average demand is 3
chemists per institution.
(ii) The major deficiencies of our chemistry graduates are:
• insufficient basic research skills,
• insufficient skills in modern equipment and computers,
• lack of environmental protection awareness , and
• insufficient exposure to analytical methods.
(iii) Respondents showed a bias towards Chemistry courses related to industries and
chemical research institutions.
(iv) Business management skills would give additional credit to our graduates in the
job market.
(v) Only about 10% of the questionnaire respondents were female, an indication of
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The recent tracer study conducted by the FoS (2002) has indicated that:
(i) Most of the chemistry and biology graduates are not self-employed and this
may be attributed to the nature of the programmes they pursued.
(ii) Departments should strive to develop programmes, which prepare graduates to
fit and serve in the labour market, particularly in the liberalized economy.
(iii) Employers and graduates are of the opinion that courses studied at the
University play an important role in securing employment.
The proposed program, therefore, has been conceived with the following in mind:
(i.) To include chemical concepts and skills which have been requested by
various chemical and allied industries and chemical research institutions,
(ii.) To include other contents that have been suggested by stakeholders in the
chemical and allied industries, including mathematics, information and
communication technology and business management and
(iii.) To prepare graduates with the skills to cope with the current and projected
demands.
1999/2000 164 40 42
2000/2001 140 46 40
2001/2002 142 45 60
2002/2003 146 54 64
2003/2004 138 82 48
2004/2005 155 116 82
Five year enrolment projections for the proposed BSc. (Chem.) programme
YEAR III - - 30 40 50
TOTAL 30 70 120 145 165
The launching of this programme will increase the total undergraduate course units
offered by the Department to the following level:
Core courses = 96 units (Theory = 78 and Practicals = 18 units)
Service courses = 21 units (Practicals = 5.5 units)
Total teaching Load = 117 units
Therefore, using the 1998 academic audit recommendations, the average teaching
load per academic staff will be as follows:
Therefore, Teaching load = 5977.5 hours/(30 weeks x 20 staff) = 9.96 hours per
week which is similar to the recommended teaching load (11 hours per week) by
the 1998 Academic audit report.
However, it should be noted that the Chemistry Department has three major areas
of specialization, namely, Inorganic/Analytical, Physical and Organic
Chemistry. Each academic staff member is qualified to teach in only one of these
areas.
FIRST YEAR
FACULTY COURSES
CODE TITLE UNITS
DS 101 Development Perspectives I 2
DS 102 Development Perspectives II 2
IS 131 Introduction to Informatics and 2
Microcomputers
TOTAL 6
CHEMISTRY COURSES
CODE TITLE UNITS
CH 100 Introduction to Physical Chemistry 2
CH 111 Basic Analytical Chemistry 2
CH 116 Basic Organic Chemistry 2
CH 121 Chemistry Practicals I 2
CH 122 Chemistry Practicals II 2
CH 170 Introduction to Electronic Structure 2
and Spectroscopy
CH 171 Methods of Chemical Separation 2
CH 175 Basic Inorganic Chemistry 2
CH 191 Theoretical Methods for Chemists 2
TOTAL 18
PRACTICAL TRAINING
CH 199 Practical Training 2
OPTIONAL COURSES
SECOND YEAR
PRACTICAL TRAINING
CH 299 Practical Training 2
OPTIONAL COURSES
THIRD YEAR
THIRD YEAR
OPTIONAL COURSES
SECOND YEAR
SEMESTER CODE COURSE TITLE UNITS TOTAL
CH 200 Chemical Thermodynamics 2
CH 241 Chemistry Practicals III 2
CH 243 Organic Chemistry II 3
I CH 244 Chemistry Practicals VII 2
13
CH 271 Structural Inorganic Chemistry 2
EV 200 Environmental Science I 2
CH 242 Chemistry Practicals IV 2
CH 245 Chemistry Practicals VIII 2
CH 248 Instrumental Methods in Analytical 2
Chemistry
II CH 261 Environmental Analytical Chemistry 2
12
CH 281 Organic Structure, Reactions and 2
Mechanisms
CH 292 Chemical Kinetics and Catalysis 2
TOTAL CORE UNITS SECOND YEAR 25
CHEMISTRY COURSES
CODE TITLE UNITS
CH 100 Introduction to Physical Chemistry 2
CH 111 Basic Analytical Chemistry 2
CH 116 Basic Organic Chemistry 2
CH 121 Chemistry Practicals I 2
CH 122 Chemistry Practicals II 2
CH 200 Chemical Thermodynamics 2
CH 241 Chemistry Practicals III 2
CH 242 Chemistry Practicals IV 2
CH 243 Organic Chemistry II 3
CH 248 Instrumental Methods in Analytical 2
Chemistry
CH 314 Project Work 3
CH 315 Surface and Colloid Chemistry 2
CH 323 Organic Spectroscopy 2
CH 341 Chemistry Practicals V 2
CH 342 Chemistry Practicals VI 2
CH 345 Quantum Chemistry 2
CH 353 Biochemistry 2
CH 357 Fuel Chemistry and Technology 2
OPTIONAL COURSES
FIRST YEAR
Course content
Electrons in atoms, the shape and energy of s, p and d atomic orbitals. Electronic
configurations of atoms, the periodic table and periodic trends. Ionization energy,
electron affinity and Hund’s rule. Isotopes.
Electrons in molecules;. Types of bonds: metallic, ionic, polar, covalent and
hydrogen bonds, bond strength. Valence Shell Electron repulsion theory. Molecular
Orbital theory, bonding and antibonding orbitals, first and second row homonuclear
diatomics, hybrid orbitals.
Overview of the electromagnetic spectrum and illustration of the basic information
derivable from different spectroscopic techniques. Absorption and emission spectra,
with particular emphasis on IR, UV and 1H n.m.r. spectroscopy of simple organic
molecules.
Text books:
1. C Lawrence, A Rodger and R Compton, Foundations of Physical Chemistry, OUP,
1996.
2. Any Organic text book with basic spectroscopy.
Course content
Sedimentation, centrifugation, filtration, crystallization, distillation, extraction,
precipitation, ion exchange, membrane, separation by gas absorption,
chromatography and electrophoresis.
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Textbooks:
1. C. E. Meloan. Chemical Separations: Principles, Techniques and Experiments.
John Wiley & Sons Inc. London, 1999.
2. R. Noble and P. Terry. Principles of Chemical Separations with Environmental
Applications. Cambridge University Press, 2003.
Course content:
Periodic properties of the elements. The representative elements: Groups I -VII and
O. Group characteristics, Trends and comparative study of the groups. Introduction
to transition metal chemistry.
Textbooks:
1. G. Rayner-Canham. Descriptive Inorganic Chemistry. W. H. Freeman and Company.
New York 1995.
2. D. F. Shriver, P. W. Atkins and C. H. Langford. Inorganic Chemistry.. 2nd Ed. ELSB, 1994.
Course contents
Differentiation: Limits and continuity of functions. Definition of the derivative of a
function. Derivation of the rules for differentiation of sums, products and quotients of
functions. Derivation of circular, exponential and logarithmic functions. Relative and
absolute maxima and minima. Graphical differentiation.
Differential equations: First order equations with separable variables. Linear first
order equations and the use of an integrating factor. Euler-Cauchy method. Second
order linear equations with constant coefficients.
Textbooks:
1. Jeffrey, A. Mathematics for Engineers and Scientists. Thomas Nelson and Sons Ltd.,
1979, UK.
2. Kreyszig, E. Advanced Engineering Mathematics, 1998.
Course content:
SI units and dimensional analysis. The treatment of experimental data focussing on
error analysis, error propagation, and the t-test. Comparison of data with theory
including linearization of equations, least squares regression and graphical methods.
Properties of matrices and their use in solving simultaneous equations in chemistry.
Review of basic calculus: the physical meaning of infinitesimal (d) and finite changes
(∆ ), and the setting up and solving of common first and second order differential
equations in chemistry. Locating and characterization of stationary points.
Eigenvalue problems in Chemistry and the meaning of eigenvalues, eigenfunctions
and eigenvectors. Complex numbers and their role in describing the atomic orbitals.
Textbooks:
1. Departmental manual.
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2. Lipschutz, S. Theory and problems of Linear Algebra. Mc Graw Hill, NY, 1974.
3. Spiegel, M. R. Theory and problems of omplex Variables, Mc Graw Hill, NY, 1974.
SECOND YEAR
CH 244 CHEMISTRY PRACTICALS VII 2 Units
Objectives
At the end of he course, students are expected to be able to:
1. apply basic chemical techniques and methods in applied chemical
experiments, and
to illustrate some aspects of chemistry as given in the lectures.
Course content
A set of experiments based on the following topics: Common laboratory techniques in
applied chemistry, calibration of basic equipment, Visible and UV spectroscopy,
potentiometry, thermodynamics, statistical analysis of data and chemical separations .
Textbooks:
1. Departmental Laboratory manuals.
2. D.T. Sawyer, W.R. Heinemann and J.M. Beebe, Chemistry Experiments for
Instrumental Methods, John Wiley and Sons Inc, N.Y. 1984.
Objectives
At the end of he course, students are expected to be able to:
1. apply basic chemical techniques and methods in applied chemical
experiments, and
2. illustrate some aspects of chemistry as given in the lectures.
Course content
Textbooks:
1. Departmental Laboratory manuals.
2. D.T. Sawyer, W.R. Heinemann and J.M. Beebe, Chemistry Experiments for
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Course content:
A theoretical discussion of the various stages in an analytical procedure: Problem
formulation and planning, Sampling strategies, Sample manipulation, conservation,
storage and work-up, (Extraction, clean-up, preconcentration, derivatization).
Instrumental analysis, Data evaluation and method validation. Methods for the
determination of ultra-trace concentrations of inorganic, organometallic and organic
compounds in air, soil, water, sediment and biota. Groupwise mini-projects (where
practical experience of problem formulation, experimental design, sampling and data
evaluation is obtained) will be done and reports assessed.
Textbooks:
1. F. W. Fifield and P. J. Haines. Environmental Analytical Chemistry, 2nd ed.
Blackwell Science, 2000.
2. M. Radojeric and V. Bashkin. Practical Environmental Analysis, Royal Society of
Chemistry, London,1999.
Objectives
At the end of the course, students are expected to be able to
1. Understand the basic concepts of coordination chemistry and
2. Relate the structure and bonding of coordination compounds with their respective
reactions.
Course content
Introduction to coordination chemistry. Constitution and stereochemistry of
coordination compounds. Hybridization and coordination numbers. Bonding in
coordination compounds. Thermodynamic and kinetic stabilities of coordination
compounds and their properties related to bonding. Chemical reaction of
coordination compounds.
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Textbook:
D. Nicholls. Complexes and First row Transition metals, MacMillan London, 1995.
Objective:
At the end of the course, students are expected to be able to understand the driving
forces and mechanistic principles of organic reactions and mechanism.
Course content:
Structure of organic compounds (molecular connectivity and molecular geometry),
Electrophilic and nucleophilic substitutions, molecular rearrangement, elimination
and addition reactions, oxidation and reduction reactions; Specificic organic
reactions: Carbanion I (Acidity of hydrogens, Aldol, Claisen and Crossed Claisen
condensation.Tautomerism, Dieckmann and Reformatsky reactions. Carbanion II
(Malonic ester and aceto-acetic ester synthesis, polyfunctional compounds;
Polynuclear aromatics, Michael addition reactions.
Text Books
1. F.A. Carey and R.J. Sundberg, Advanced Organic Chemistry Part A & B, 3th ed.
Plenum Press, N. Y. (1991).
2. J. March, Advanced Organic Chemistry, 4th ed. John Wiley &Sons, N. Y. (1992).
3. R.O.C. Norman and J.M. Coxon, Principles of Organic Synthesis, 3rd ed. Blackie
Academic & Professional, London, (1995).
Objectives
At the end of the course, students are expected to be able to:
1. Understand the basic concepts of chemical kinetics and catalysis,
2. Apply chemical kinetics in chemical reactions and reactor designs, and
3. Formulate intrinsic rate equations at the catalyst sites and in solutions
Course Content:
Kinetics theory of gases, Distribution of velocities, Collision cross section. Collision
frequency, Mean free Path. Rate laws and their determination, Temperature
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Textbooks:
1. P. Atkins and J. de Paula, Physical Chemistry, Oxford University Press, 7th
Ed., London, 2002.
2. S. R Logan, Fundamentals of Chemical Kinetics, Longman, Harlow, 1996.
Reference books:
1. M. Boudart. Kinetics of Chemical processes, Butterworth, London, 1991.
2. M.R. Wright, Introduction to chemical kinetics, John Wiley and Sons Inc, NY
2004.
3. Any introductory book on chemical kinetics and reaction dynamics.
Objective
At the end of the course, students are expected to be able to understand the
structure and properties of crystalline materials.
Course Content
Introduction to Group theory of molecules and ions. Basic crystal structures of the
elements and simple ionic compounds. Packing. Crystal planes. Structural defects.
Intermolecular forces: Nature and properties of metals (conductors), semiconductors
and insulators (non conducting solids). Structure of clays and some simple minerals.
Key books:
1. A.R. West. Solid State Chemistry and its Applications, Wiley & sons 1984.
2. J. E. Huheey, J. E. Inorganic Chemistry: Principles of Structure and Reactivity, 4 th
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Ed.
Objective
At the end of the course, students are expected to be able to
1. Understand the synthesis and processes of technologically important materials,
2. design structures of potentially new molecules, and
3. use techniques obtained from the lectures to interpret spectra from AFM,
SEM, FT-IR and EQCM spectrometers.
Course content
Chemical and physical properties of technical materials (polymers, zeolites, silica,
alumina, activated carbons, clays, ceramics, dense microcrystalline oxides);
Reaction mechanisms of inorganic and organic polymerisation; Molecular design
and synthesis of functional materials, electrochromic devices, smart windows,
biosensing materials, amphiphilic polymers, optical devices and nanomaterials.
Polymer degradation, conducting polymers and semiconductors ferrous and
nonferrous metallurgy. Characterisation of materials: surface area of porous
materials, pour size distribution analysis, porosity analysis, AFM, SEM, FT-IR
EQCM, Auger spectroscopy and thermal analysis.
Text books:
1. I.M. Campbell. Introduction to synthetic polymers, Oxford Science Publishers
Van vlack Materials science for Engineers, Addison Wesley Publishing
Company, 1982.
2. M. E. Brown; Introduction to thermal analysis Techniques and applications;
Chapman and Hall, 1988.
Reference books:
1. C. R. Brundle, C. A. Evans Jr. and S. Wilson. Encyclopedia of materials
characterization; Butterworth –Heinemenn, Boston, 1992.
2. I. Rubinstein. Physical Electrochemistry principles, methods and applications.
Marcel Dekker Inc., New York, 1995.
3. Southampton Electrochemistry group. Instrumental methods in
electrochemistry. Ellis Horwood, New York 1990.
Course Content
Experimental design. Multivariate data analysis, including Principal component
analysis (PCA). Building Linear Predictive models, including Principal Component
Regression (PCR) and Projection to Latent Structures by means of Partial Least
Squares (PLS).
Text books:
1. J.N. Miller and J.C. Miller, Statistics and chemometrics for analytical chemistry 4 th
ed. Prince Hall, London, 2000.
2. Umetrics AB. Introduction to Designs of Experiments. 1998
3. Umetrics AB. Introduction to Multi- and Mega-variate data analysis. 1998
Course content
Analytical method development, sampling and sample collection, sample
preparation, dissolution methods, measurement techniques to include ICP-AES,
ICP-MS, flow injection, X-ray fluorescence and stripping voltammetry, sensitivity and
detection limit, calibration, data quality, results and presentation and an overview of
EPA and other standard methods applied in analytical chemistry.
Textbooks:
1. D. A. Skoog, F.J. Holler and T. A. Nieman. Principles of Instrumental
Analysis. Harcourt Brace & Co., 1998.
2. J. R. Dean. Extraction Methods for Environmental Analysis. John Wiley;
NY, 1998.
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Objectives
At the end of he course, students are expected to be able to:
1. Understand the wide-ranging applications of chemical speciation in a modern
society, and
2. Use techniques of chemical speciation in the analysis aqueous systems.
Course content:
Introduction to chemical speciation analysis, strategies for the analysis of labile
equilibrium systems including sampling, electrochemical methods in speciation
studies, equilibrium dialysis, ultra-filtration and size exclusion chromatography
coupled with AAS as detection methods for speciation, the scope and application of
chemical speciation analysis, analysis of speciation forms of metal ions species as
essential and contaminating species in different aquatic systems, speciation for
optimisation of aqueous based chemical processes, potential future application of
chemical speciation analysis especially in integrated pollution control.
Textbooks:
1. J. A C Broekart, S Gucer and F Adams (eds). Metal
Speciation in the Environment. Springer-Verlag, Berlin, 1990.
2. Chemical Speciation in the Environment. A M Ure and C
M Davidson (Eds), Blackie, Glasgow, 1995.
3. A G Howard. Aquatic Environmental Chemistry, Oxford
Chemistry Primers (57), Oxford University Press. 1998.
4. P Quevauviller. Method Performance Studies for
Speciation Analysis, Royal Society of Chemistry. 1999.
Objective
At the end of he course, students are expected to be able to describe in detail the
analytical techniques associated with drug, food, poisons and explosives.
Course content
Introduction to forensic science and analysis, methods for drug identification,
methods for toxicology determination, quality control in forensic analysis, drug
screening by Immunoassay, TLC, GC-NPD and HPLC, spot testing for illicit
substances and anabolic steroids, sample preparation of biological
specimens/evidence, serological evidence and its analysis, DNA Analysis, Gunshot
residue analysis, trace evidence analysis, hair and fiber analysis, paint evidence
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Textbooks:
1. G. Davis. Forensic Science, American Chemical Society, Washington, DC, 1986.
2. M. H. Ho. Analytical Methods in Forensic Chemistry, Ellis Horwood, Ltd., London,
1990.
Objectives
At the end of he course, students are expected to be able to:
1. Understand the basic concepts of food chemistry and technology, and
2. Understand the processes involved in the manufacture of various beverages
including wines, liquors etc.
Course content
Food components: carbohydrates, lipids, proteins and vitamins. Food coloring and
aroma. Food and milk processing. Food by-products processing. Sugar industry.
Starch and related polysaccharides. Fermentation industries: wine, liquors. Quality
preservation and hygiene in food processing.
Textbooks
1. H.D. Belitz and W. Grosch. Food Chemistry, Springer Berlin, 1987.
2. T.P. Coultate. Food: The Chemistry of its components, 2 nd ed. The Royal Society
of Chemistry, London, 1988.
Course content.
Basics of Fourier Transform NMR and its advantages. 1D NMR applications such as
double resonance, nOe difference spectroscopy, 2D NMR applications such as
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Textbooks:
1. Structure Elucidation by NMR in Organic Chemistry. E. Breitmaier. John Wiley and
Sons, New York, 1995.
2. R. M. Silverstein, G. C. Bassler and T. C. Morill. Spectroscopic identification of
organic compounds. 5th Ed. John Wiley and Sons, NY, 1991.
Objectives:
At the end of he course, students are expected to be able to
1. Understand the principles of quality, good laboratory practices and good
manufacturing practices and how these may be attained, monitored and
controlled.
2. Describe wastes and waste management strategies in pollution prevention.
Course content
Principles of quality systems, elements of quality manuals, quality control and quality
assurance activities that provide confidence that a product or a service. Good
laboratory practices (GLP) and Good Manufacturing Practices (GMP). Control charts
in monitoring quality. Sampling, records, personnel requirements and the
management of equipment, supplies and chemicals in achieving quality output.
Methods of analyses, instrument performance, method validation, proficiency testing,
audit procedures, accreditation and International Standards Organisation (ISO)
documents, ISO 17025 and 9001, as quality assurance requirements. Types of
wastes, waste analysis and waste management strategies to include waste
minimisation, recycling, onsite/offsite treatment, disposal, ‘green’ chemistry in waste
prevention and ISO 14001.
Textbooks:
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1. P. T. Williams, Waste Treatment and Disposal, John Wiley and Sons Ltd, NY,
1998.
2. H. Tammemagi. The Waste Crisis: Landfills, Incinerators and the Search for a
Sustainable Future, Oxford University Press Inc, USA, 2000.
3. O. P. Kharbanda, Waste Management: Towards a Sustainable Society E.A.
Stallworthy Greenwood Press, 2000.
Objectives
At the end of he course, students are expected to be able to
• Understand how molecular symmetry influences measurable properties of
systems, especially the IR and Raman spectra of simple molecules, and
• Understand the principles of equilibrium statistical mechanics.
Course content
Molecular energy level thermodynamics (M.E.L.T.) and its relationships to classical
thermodynamics: the canonical ensemble and molecular partition functions for non-
interacting particles. Derivation of the Boltzmann distribution. Distinguishable and
non-distinguishable particles. Calculation of equilibrium constants and rate constants
for simple reactions from molecular energy levels. Nuclear statistics in terms of
bosons and fermions.
Group theory and its application to the vibrational spectra of simple polyatomic
molecules. Symmetry adapted orbitals and bonding in simple polyatomic molecules.
Hűckel theory.
Textbooks
1. F. A. Cotton: Chemistry Applications of Group Theory, 2nd ed., Wiley Eastern
Ltd. 1992
2. A. K. Chandra: Introductory Quantum Chemistry, 3rd ed., Tata MaGraw Hill,
1988.
3. P. W. Atkins, Physical Chemistry. 6th ed. ELBS/Oxford Univ. press, London,
1998
Objectives
At the end of he course, students are expected to be able to
37
Course content
Nature of organometallic compounds. Nomenclature Behavior of metals toward
organic systems. Nature of the carbon-metal bond. Transition metal compounds with
bonds to hydrogen and carbon, and hydrogen to boron. Chemical behaviour of
carbon-metal bonds. Transition metal to carbon bonds in synthesis and catalysis.
Transition metal complexes. . Industrial applications of organometallic compounds.
Text books:
1. M. Bochmann. Organometallics 1 & 2, (Zeneca series no. 12 & 13) Oxford
Science Publications. 1994.
2. P. Powell. Principles of Organometallic Chemistry, Second Edition. Kluwer
Academic Publishers, 1998.
Objectives
At the end of the course, students are expected to be able to
1. Understand the important roles of metal ions in biological systems, and
2. describe the structure and function of metal ion sites in biomolecules.
Course content
Metal coordination environments in biology. Iron transport and storage, oxygen
binding in mammals and lower organisms, the use of model compounds as probes
of biological structures. Electron transfer, the toxicity of inorganic species, the use of
metal complexes as drugs. Platinum anticancer drugs, discovery of cis-platin. Metal
toxicity, electron transfer in biology, Redox activation of N2. Alkali metals ions and
nitric oxide in communication.
Text books:
1. W. Kaim and B. Schwederski, Bio-inorganic Chemistry: Inorganic Elements in
the Chemistry of Life, Wiley, N.Y., 1994.
Objectives:
At the end of the course, students are expected to be able to:
• understand the organic chemistry of biological molecules.
• understand the structure and reactivity of the small organic building block of
polymeric bio-molecules of life and appreciate their function in living cells, and
• pursue careers in the pharmaceutical, biotechnological, biochemical and
medical sciences.
Course content
Enzymology: Basic Kinetics and Michaelis-Menten Equation, equilibrium and steady
state assumptions; Enzyme inhibition; Serine proteases: structure, selectivity and
kinetics; Transition state theory as applied to enzymes: Entropy effects on enzyme
reactions, transition state stabilization, transition state analogues as inhibitors; Ion
channels, receptors, and blockers; Chemical biology: Ca sensors and caged
compounds; Cofactor Chemistry: NADPH, Pyridoxal, Flavins, folate, biotin, thiamine;
Nucleic acid chemistry: DNA and RNA structures, design of specific DNA binding
and cleaving agents, catalysis of RNA, Amino acids and proteins; Sugars and
carbohydrates; Lipids.
Textbooks:
1. C.M. Dobson, J.A. Gerrard and AJ Pratt. Foundations of Chemical Biology, Oxford
University Press, Oxford, 2002.
2. H. Hermann. Bio-organic Chemistry, 3rd ed. Springer-Verlag, New York, 1999,
Reference book:
1. J. McMurry. Organic Chemistry, 5th Ed., Brooks/Cole Publishing Co., Belmont,
1999.
Objectives
At the end of he course, students are expected to be able to
1. Apply advanced experimental methods of analytical and inorganic chemistry
in various experiments, and
2. Analyse trace compounds in the environment.
Course content
A set of experiments based on the following topics: instrumental chemical
separations and analysis, chemical kinetics, environmental analytical chemistry,
metallurgy, industrial inorganic chemistry, electrochemistry, industrial organic
39
Textbooks:
1. Departmental Laboratory manuals.
2. D.T. Sawyer, W.R. Heinemann and J.M. Beebe. Chemistry Experiments for
Instrumental Methods, John Wiley and Sons, Inc. NY, 1984.
Course content
Various aspects of physical organic chemistry are treated. These include basic
principles such as the preparation, stability and reactions of reactive intermediates
eg. carbonium ions, carbanion, radicals and carbenes. Various factors which
influence reaction rates, reaction sites and direction of incoming groups, as well as
the stereochemical outcome of products will be discussed in the course.
Text Books
1. F.A. Carey and R.J. Sundberg, Advanced Organic Chemistry Part A & B, 3th ed.
Plenum Press, N. Y. (1991).
2. J. March, Advanced Organic Chemistry, 4th ed. John Wiley &Sons, N. Y. (1992).
3. R.O.C. Norman and J.M. Coxon, Principles of Organic Synthesis, 3rd ed. Blackie
Academic & Professional, London, (1995).
wide, and
2. Understand how the principles of organic synthesis are applied in the
manufacture of commercially important natural and artificial (complex and
simple) molecules/compounds.
Course content:
An overview of organic chemistry and industry, raw materials for organic chemical
industries, principles of organic synthesis (C-C bond forming strategies, FGIs,
chemo- and stereo-selectivity), planning of organic synthesis (retrosynthetic
analysis), syntheses of some commercially important organic compounds: dyes,
pharmaceuticals, pesticides, fragrances, flavourings, soaps, detergents, adhesives,
sealants, coatings, food additives, etc.
Text Books
1. B.G. Reuben, Industrial Organic Chemicals in Perspective. Vol. I & II, Wiley &
Sons, London, 1980.
2. S. Warren. Organic Synthesis: The Disconnection Approach. Wiley & Sons,
London, 1997.
3. R.O.C. Norman and J.M. Coxon, Principles of Organic Synthesis, 3rd ed. Blackie
Academic & Professional, London, (1995).
4. M. B. Smith, Organic Synthesis. McGraw-Hill, (1994)
Objectives
At the end of he course, students are expected to be able to understand electrode
kinetics, mechanisms, electrochemical processes and measurements.
Course Content
Electrode kinetics and Mass transport; Electrode-Solution interface: over potential,
ohmic, activation and concentration polarization Nernst diffusion layer; Tafel
equation, i-V polarization principles; Principles, mechanisms and control of
corrosion; Industrial applications: fuel cells, batteries and electroplating;
Electrochemical techniques: impedance spectroscopy, cylic voltametry,
potetiodynamic polarization etc.
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Text books:
1. E. Gileadi: Electrode Kinetics for Chemists, Chemical Engineers and Material
Scientists, VCH 1993.
2. J.S.Newman. Electrochemical Systems. 2nd ed. Prentice Hall 1991.
3. A. C. Fisher; Electrode Dynamics; Oxford University Press, Oxford, 1998
Reference books:
4. I. Rubinstein. Physical Electrochemistry principles, methods and applications.
Marcel Dekker Inc., New York, 1995.
5. Southampton Electrochemistry group. Instrumental methods in
electrochemistry. Ellis Horwood, New York 1990.
6. Trethewey, K.R. and Chamberlain J.: Corrosion for students of Science and
Engineering, Longman, 1988.
7. I. Rubinstein. Physical Electrochemistry principles, methods and applications.
Marcel Dekker Inc., New York, 1995.
8. Southampton Electrochemistry group. Instrumental methods in
electrochemistry. Ellis Horwood, New York 1990.
Course content
Molecular mechanics with empirical force fields, modeling conformational changes in
organic molecules. Molecular simulation using Monte Carlo and Molecular Dynamics
techniques. Quantum molecular modeling of structure and properties of molecules.
Application of these techniques in areas such as solid state chemistry, surface
chemistry, industrial chemistry, drug design and understanding liquids, gels and
liquid crystals.
Text books:
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15.0 REFERENCES
16.0 APPENDICES
APPENDIX II
35 X-ray crystallography 14 37
36 Statistical thermodynamics 13 34
37 Asymmetric synthesis 11 29
38 Quantum chemistry 10 26
39 Radio chemistry 10 26
40 Symmetry and group theory 9 24
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APPENDIX IV
Sources:
1. COPE. Laboratory Equipment and Scientific Instruments, 2002.
2. Mettler Toledo. 2000.
3. Brinkmann Laboratory Products, 1999.
4. Scan Tanzania Limited, 2004
50
APPENDIX V
ESTIMATED BUDGET (BASED ON 2004/05 FIGURES) FOR PRACTICAL
TRAINING