Synthetic peptide with Botox-like activity —] [MIMIC FACIAL WRINKLES PRESSURE ON THE SKIN the ing al sles of the Botox alternative Painless (BoNT) Non-invasive treatment. Cost No side effets Efectve (canker wines) Pesta lateral Tne fold (cow's ed al Maysmal ols “turey ne WH Blorer rose Upper ip wrnkes — Grabellar frown lines of the formation SNARE complex BoNT-L PEPTIDE (Botox like) DECONTRACTOR mechanism of action The SNARE proteins are: syaptobrevinVAMP, SNAP 25 (Synaptosomal Associated Protein) and Syntaxin (STNX) They form a complex with the ATPase NSF (SNARE complex) The SNARE comple is involve in the teatfcking ofthe synaptic sic containingneurotransritters tothe presynaptic membrane. Fusion and exocytosis of the neurotransmi mechanism of action BoNT-L-peptide inactivates SNAP-25 from the SNARE complex. Prevents the fusion ofthe acetycholine fle vesicle with the plasmatie membrane The consequence isthe prevention of the release of acetychotine Into the synaptic ele f= of human skin ‘Acream containing 5% BoNT-L Peptide was tested during 28 days fon 15 volunteers. Results: an average reduction of 38% 107 > PB Sd. MICO BON Pepe — Ponder SSAACOD in tL of uate ox Ae BNL Pepin os slaon 25% www.infinitecces