8 Steps to Change 

Your DNA – and Your  Destiny – Now 
By: Al Sears,  M.D. 
   Wellness Research & Consulting                                                                                        © Copyright 2010 All Rights Reserved | Al Sears, MD   

Al Sears, M.D.  Wellness Research & Consulting   

researchers wanted to figure out why one twin had an autoimmune disease like lupus. As it turns out. Express the Genes That Fight Disease… The impact of this study is far reaching. If you think there’s nothing you can do to prevent getting a disease that runs in your family. The evidence is startling: A study I read in Genome Research shows how one twin avoided disease while the other didn’t. . You have some control over whether or not a disease catches up with you. It’s putting to rest the long-held belief that you’re stuck with what you got at birth. You don’t have to sit and wait to get sick.”1 How was this possible? The choices each twin made had literally reprogrammed their DNA. Much to the surprise of the old way of thinking. think again. and the other one didn’t. you can literally reprogram your DNA – telling your body to slow aging. The twin that didn’t get lupus had genes that were programmed to keep the disease at bay. despite sharing identical genes. The one that did have it had that particular gene expression turned “on. your fate isn’t sealed by your DNA. Identical twins share 100% of the same DNA. Not only do they share the same looks. For the study. live longer. 2010. issue of TIME magazine? The cover story presents some exciting new research.You’re Not Stuck With Your Family’s Genes Have you seen the January 18th. Just because a disease like cancer runs in your family doesn’t mean you’re helpless. Emerging New Science Puts You in the Driver’s Seat This new branch of science is called epigenetics. The answer was found in their DNA. they also usually share the same disorders and ailments. and prevent diseases.

Everything from the detergent you use to clean your clothes to the plastic bottles you drink from are to blame. That’s because your body is constantly absorbing toxins like heavy metals and harmful chemicals. Did you know that any changes in your genetic expression made during your lifetime may get passed on to your children? A study in the Proceedings of the National Academy of Sciences studied two groups of genetically identical pregnant mice. like grass-fed beef or free-range chicken. The actions you take today will most likely affect them and their own children. healthier. and poor diets also interact with the epigenome. Here are 8 steps to change your DNA – and your destiny – now… Step 1: Eat whole. Avoid bad habits like smoking. The good news is. All these negatively affect your genes and predispose you to disease. the epigenome is a complex network of chemical switches. Both groups of mice gave birth to female mice. this is huge. unprocessed foods. taking control of your genetic code is simpler that you might think. Live Longer. folate. Smoking.” But here’s where it gets interesting. telling it to switch on the “disease” genes. Both groups were fed a normal diet. . One of the easiest ways to affect your gene expression in this lifetime is to live in a healthy environment. disease-free life. excess alcohol. Simply put. These switches surround your DNA and turn genes “on” and “off. That means eating a similar diet to that of our ancestors. That means everything you come into contact with and everything you put into your body has the power to turn genes on or off via different chemical pathways. By doing so. you’ll boost your chances of living a longer. 2 If you’re planning on having kids. Step 2: Choose healthy proteins. The end result? The original “grandparent” group that received supplements passed on the changes in gene expression to the children and grandchildren. and choline). Your epigenome interacts every day with your environment. The only exception was that the second group received supplements that positively affect gene expression (B12. zinc. It’s just a matter of developing good habits that promote positive gene expression. The end result is the ability to change the way your body expresses your genetic coding.Change Your Children’s Genes The “epigenome” makes this possible. Those mice then gave birth as well. Take personal responsibility and eat right and exercise. Beat Disease Today’s modern world is already predisposing your genes toward negative “expressions” that include disease. Wild-caught fish is good as well. excess drinking. and eating chemical-laden junk foods.

000 to 2. Marcus Pembrey. emeritus professor. Institute of Child Health. References:    1. Otherwise you can supplement. M. this keeps you vibrant and healthy. Javierre BM. They contain critical methyl-precursors. Oakland.Step 3: Eat plenty of vegetables and some fruits (preferably berries. Found To Keep  Hearts Young. pages 415‐424. the participants in the study had experienced a positive change in 1. David I. Substance In Red Wine. Martin. K. the telomeres become shorter.  3. “Fish‐oil supplementation induces anti‐inflammatory gene expression profiles in  human blood mononuclear cells” American Journal of Clinical Nutrition. Take anywhere from 100 to 500 mcg every day. Bouwens. The best way to get your omega-3s is with a quality fish oil supplement. 13‐18. Resveratrol. It also prevents harmful substances in the environment from blocking vital chemical processes your DNA goes through to stay healthy and intact. as they’re high in protective antioxidants).  Nov. Step 4: Take omega-3 fatty acids daily. One of the best food sources are egg yolks and grass-fed beef. M. SAMe is a power methyl-donor. Step 6: Take SAMe (s-adenosylmethionine). Step 8: Keep your heart and lungs in good shape.D. I suggest 200 mg per day.3 After just six months.4 That means it prevents your DNA strands from deteriorating.” Genome Res.. One study in the American Journal of Clinical Nutrition found that taking omega-3 daily tells your genes to prevent inflammation and hardening of the arteries.. Simply put. Think of them as the biological countdown clock that tells your cells how long they have to live. Children's Hospital Oakland Research Institute.K. Ultimately. 2006. Volume 90. June 8).D. University of Wisconsin‐Madison (2008.   . As your cells divide. Richter J. the cell dies. letting them live longer. June  2009   4.040 of their genes. University College London. You can find resveratrol as a supplement at your local health-food store. Step 5: Take a red wine extract supplement. ScienceDaily. Once there’s no more telomere left. Not only will this prevent a slew of diseases on its own. These are compounds that play an important role in the chemical process that actually changes gene expression. This natural and inexpensive vitamin affects how long your DNA strands live. [Epub ahead of print]  2. 2009 Dec 22. Calif. It has recently been found to counteract age-related genetic change 92 percent of the time.  M.000 mg per day. Step 7: Get plenty of vitamin B12. Resveratrol is a powerful antioxidant found in red wine. Telomeres are a “tail” end to all your strands of DNA. it’ll also make your body better able to respond to negative environmental factors. et al.. et al. Fernandez AF. Take 200 mg of SAMe per day for maximum benefit. it provides your epigenome with the critical building blocks it needs to switch your “good” genes on. pediatric genetics. U. “Changes in the pattern of DNA methylation associate with  twin discordance in systemic lupus erythematosus. O. Proceedings of the National Academy of Sciences. It does this by lengthening your DNA’s telomeres. Aim for 1. Exercise as I describe in my PACE program.