Heptaobiliary System The space of Disse is in the liver.

The space of Disse is also

called the perisinosoidal space. It is the space between the
1. Which of the following is the exocrine portion of the liver sinusoids and the hepatocytes.
pancreas?
a. Islets of Langerhans The space of Mall is also in the liver. The space of Mall is
located at the portal canal and is the region between the
b. Alpha cells
connective tissue and the liver parenchymal cells. It is the
c. Beta cells site where lymph is formed within the liver.
d. Delta cells
e. Acini A vacuole is a small clear space within an individual cell.

The pancreas is both an endocrine and exocrine organ.
The endocrine portion of the pancreas is housed in the islets
of Langerhans. Within the islets, there are several cell types.
The alpha cells secrete glucagon. The beta cells secrete
insulin. The delta cells secrete somatostain. The gamma cells
secrete pancreatic polypeptide.
The acini is the exocrine portion of the pancreas.
2. What are divertiuclae of the mucosa of the
gallbladder called?
a. Rokitansky-Aschoff sinuses
b. Ducts of Luschka
c. Duct of Wirsung
d. Ampulla of Vater
e. Sphincter of Oddi
Rokitansky-Aschoff sinuses are divertiuclae of the mucosa
of the gallbladder. The small bile ducts which connec
between the cystic duct and liver are the ducts of Luschka
The duct of Wirsung is the pancreatic duct. The opening of
the pancreatic duct into the duodenum is at the ampulla of
Vater. The valves which regulates the flow of bile into the
small intestine is the sphincter of Oddi.
3. What structure is in the middle of the hepatic
lobule?
a. Hepatic artery
b. Portal triad
c. Central vein
d. Portal vein
e. Sinusoids
Hepatocytes are the liver cells. They are arranged to form a
liver lobule, which is the functional unit of the liver. The
liver lobule is a hexagonal shaped structure. At the angles of
the liver lobule are portal triads. The portal triad is
composed of a branch of the hepatic artery, portal vein, and
bile duct. In the middle of the liver lobule is a central vein.
Hepatic sinusoids run between the hepatocytes.
4.What is the space between the liver sinusoids and the
hepatocytes called?
a. Space of Disse
b. Space of Mall
c. Vacuole
d. Lacuna
e. Howship's lacuna
A lacuna is a small space or depression. The space that the
chondrocyte rests in is a lacuna.
Howship's lacuna is seen in bone. Howship's lacuna is a
space seen underneath an osteoclast.
5. What is the name of the cellular mass for the
endocrine portion of the pancreas?
a. Islets of Langerhans
b. Alpha cells
c. Beta cells
d. Delta cells
e. Acini
The pancreas is both an endocrine and exocrine organ.
The endocrine portion of the pancreas is housed in the islets
of Langerhans. Within the islets, there are several cell types.
The alpha cells secrete glucagon. The beta cells secrete
insulin. The delta cells secrete somatostain. The gamma cells
secrete pancreatic polypeptide.
The acini is the exocrine portion of the pancreas.
6. Which structures are part of the portal triad?
a. Portal vein
b. Hepatic artery
c. Central vein
d. Sinusoids
e. Both a and b
Hepatocytes are the liver cells. They are arranged to form a
liver lobule, which is the functional unit of the liver. The
liver lobule is a hexagonal shaped structure. At the angles of
the liver lobule are portal triads. The portal triad is
composed of a branch of the hepatic artery, portal vein, and
bile duct. In the middle of the liver lobule is a central vein.
Hepatic sinusoids run between the hepatocytes.
7. Which of the following is NOT a function of the
liver?
a. Metabolism of bilirubin
b. Deamination of amino acids
c. Storage of iron
d. Storage of copper
e. Storage of calcium
The liver performs many, many functions. Estimates range The acini is the exocrine portion of the pancreas.
at over 500 different functions for the liver.
1. What is the opening of the pancreatic duct into the
Bilirubin is metabolized in the liver. The conversion of duodenum?
amino acids to carbohydrates through the process of a. Rokitansky-Aschoff sinuses
deamination occurs in the liver. Iron is stored in the liver as
b. Ducts of Luschka
ferritin. Copper is stored in the liver.
c. Duct of Wirsung
d. Ampulla of Vater
The storage site for calcium is in the bones.
e. Sphincter of Oddi
Histology hint from Sarah Bellham: If ever asked where a
process occurs, and you absolutely have no idea, make an Rokitansky-Aschoff sinuses are divertiuclae of the mucosa
educated guess of the liver. of the gallbladder. The small bile ducts which connect
between the cystic duct and liver are the ducts of Luschka
The duct of Wirsung is the pancreatic duct. The opening of
8. What is the functional unit of the liver? the pancreatic duct into the duodenum is at the ampulla of
a. Lobule Vater. The valves which regulates the flow of bile into the
b. Portal triad small intestine is the sphincter of Oddi.
c. Central vein
d. Hepatocyte 2. Which of the following is the exocrine portion of the
e. Sinusoids pancreas?
a. Islets of Langerhans
Hepatocytes are the liver cells. They are arranged to form a b. Alpha cells
liver lobule, which is the functional unit of the liver. The c. Beta cells
liver lobule is a hexagonal shaped structure. At the angles of d. Delta cells
the liver lobule are portal triads. The portal triad is
e. Acini
composed of a branch of the hepatic artery, portal vein, and
bile duct. In the middle of the liver lobule is a central vein.
Hepatic sinusoids run between the hepatocytes. The pancreas is both an endocrine and exocrine organ.

9. What are the valves which regulates the flow of bile The endocrine portion of the pancreas is housed in the islets
of Langerhans. Within the islets, there are several cell types.
into the intestine?
The alpha cells secrete glucagon. The beta cells secrete
a. Rokitansky-Aschoff sinuses insulin. The delta cells secrete somatostain. The gamma cells
b. Ducts of Luschka secrete pancreatic polypeptide.
c. Duct of Wirsung
d. Ampulla of Vater The acini is the exocrine portion of the pancreas
e. Sphincter of Oddi
3. Which of the following clotting factors is NOT
Rokitansky-Aschoff sinuses are divertiuclae of the mucosa produced in the liver?
of the gallbladder. The small bile ducts which connec
a. Factor I
between the cystic duct and liver are the ducts of Luschka
The duct of Wirsung is the pancreatic duct. The opening of b. Factor II
the pancreatic duct into the duodenum is at the ampulla of c. Factor IV
Vater. The valves which regulates the flow of bile into the d. Factor IX
small intestine is the sphincter of Oddi. e. Factor X

10. What cells of the pancreas secrete somatostatin? The liver performs many, many functions. Estimates range
a. Islets of Langerhans at over 500 different functions for the liver.
b. Alpha cells
c. Beta cells The liver makes clotting Factors I, II, VII, IX, and X.
d. Delta cells Fibrinogen is Factor I. Prothrombin is Factor II. Factor IV is
calcium, which is not produced in the liver.
e. Gamma cells
Histology hint: If ever asked where a process occurs, and
The pancreas is both an endocrine and exocrine organ.
you absolutely have no idea, make an educated guess of the
liver.---Sarah Bellham
The endocrine portion of the pancreas is housed in the islets
of Langerhans. Within the islets, there are several cell types.
The alpha cells secrete glucagon. The beta cells secrete
insulin. The delta cells secrete somatostain. The gamma cells
secrete pancreatic polypeptide.
4. In what structure does blood run through between 7. What cell type makes up the mucosa of the
the hepatocytes? gallbladder?
a. Hepatic artery a. Simple squamous epithelium
b. Portal triad b. Simple cuboidal epithelium
c. Central vein c. Simple columnar epithelium
d. Portal vein d. Stratified squamous epithelium
e. Sinusoids e. Transitional epithelium

Hepatocytes are the liver cells. They are arranged to form a
liver lobule, which is the functional unit of the liver. The
liver lobule is a hexagonal shaped structure. At the angles of
the liver lobule are portal triads. The portal triad is
composed of a branch of the hepatic artery, portal vein, and
bile duct. In the middle of the liver lobule is a central vein.
Hepatic sinusoids run between the hepatocytes.
5. What is the space called that is located at the portal
canal between the hepatocytes and connective tissue?
a. Space of Disse
b. Space of Mall
c. Vacuole
d. Lacuna
e. Howship's lacuna
The space of Disse is in the liver. The space of Disse is also
called the perisinosoidal space. It is the space between the
liver sinusoids and the hepatocytes.
The mucosa of the gallbladder is made of simple columnar
epithelium.
8. What is the classification of the pancreas?
a. Mixed
b. Endocrine
c. Exocrine
d. Both endocrine and exocrine
e. None of the above
The pancreas is both an endocrine and exocrine organ.
The endocrine portion of the pancreas is housed in the islets
of Langerhans. Within the islets, there are several cell types.
The alpha cells secrete glucagon. The beta cells secrete
insulin. The delta cells secrete somatostain. The gamma cells
secrete pancreatic polypeptide.
The acini is the exocrine portion of the pancreas.

The space of Mall is also in the liver. The space of Mall is 9. Which cell is a hepatic macrophage?
located at the portal canal and is the region between the
connective tissue and the liver parenchymal cells. It is the
a. Kupffer cells
site where lymph is formed within the liver. b. Histiocyte
c. Dust cell
A vacuole is a small clear space within an individual cell. d. Langerhans cell
e. Microglia
A lacuna is a small space or depression. The space that the
chondrocyte rests in is a lacuna. Macrophages are mononuclear phagocytes. Many tissues
have resident (fixed) macrophages. Fixed macrophages are
given a unique name, depending on the tissue that they are
Howship's lacuna is seen in bone. Howship's lacuna is a
located in. Kupffer cells are the hepatic macrophages.
space seen underneath an osteoclast.
Histiocytes are macrophages seen in connective tissue. Dust
cells are alveolar macrophage found in the respiratory tract.
6. What layer is NOT found in the gallbladder? Langerhans cells are macrophages seen in the skin.
a. Mucosa Microglia are the central nervous system macrophages.
b. Muscularis mucosa
c. Muscularis 10. Where in the pancreas are islets of Langerhans
d. Adventita most numerous?
e. Serosa a. Head
b. Body
The gallbladder is comprised of three layers: mucosa, c. Tail
muscularis, and adventita or serosa. Serosa is found on the d. Evenly distributed
free surface of the gallbladder. The mucosa is simple e. Depends on the individual
columnar epithelium and lamina propria. There is no
muscularis in the mucosa of the gallbladder.
Islets of Langerhans are most numerous in the tail of the
pancreas.
1. What cells of the pancreas secrete insulin?
a. Islets of Langerhans
b. Alpha cells
c. Beta cells
d. Delta cells
e. Gamma cells
The pancreas is both an endocrine and exocrine organ.
The endocrine portion of the pancreas is housed in the islets
of Langerhans. Within the islets, there are several cell types.
The alpha cells secrete glucagon. The beta cells secrete
insulin. The delta cells secrete somatostain. The gamma cells
secrete pancreatic polypeptide.
The acini is the exocrine portion of the pancreas.
2. What is the pancreatic duct?
a. Rokitansky-Aschoff sinuses
b. Ducts of Luschka
c. Duct of Wirsung
d. Ampulla of Vater
e. Sphincter of Oddi
Rokitansky-Aschoff sinuses are divertiuclae of the mucosa
of the gallbladder. The small bile ducts which connec
between the cystic duct and liver are the ducts of Luschka
The duct of Wirsung is the pancreatic duct. The opening of
the pancreatic duct into the duodenum is at the ampulla of
Vater. The valves which regulates the flow of bile into the
small intestine is the sphincter of Oddi.
3. What structure is at the angle of the liver lobule?
a. Lobule
b. Portal triad
c. Central vein
d. Hepatocyte
e. Sinusoids
Hepatocytes are the liver cells. They are arranged to form a
liver lobule, which is the functional unit of the liver. The
liver lobule is a hexagonal shaped structure. At the angles of
the liver lobule are portal triads. The portal triad is
composed of a branch of the hepatic artery, portal vein, and
bile duct. In the middle of the liver lobule is a central vein.
Hepatic sinusoids run between the hepatocytes.
4. Which of the following is NOT a function of the
liver?
a. Cholecystokinin production
b. Bile production
c. Detoxification
d. Albumin production
e. Synthesis of clotting factors
The liver performs many, many functions. Estimates range
at over 500 different functions for the liver.
Bile production occurs in the liver. The liver receives blood
from the hepatic artery and hepatic portal vein. The blood in
the hepatic portal vein is the "first stop" directly from the
intestines, giving the liver the prime opportunity to detoxify
substances. The liver synthesizes proteins such as albumin,
fibrinogen, and prothrombin. Fibrinogen (Factor I) and
prothrombin (Factor II) are clotting factors involved in
clotting. The liver also makes Factors VII, IX, and X.
Cholecystokinin is produced by the mucosa of the
gastrointestinal tract.
Histology hint from Sarah Bellham: If ever asked where a
process occurs, and you absolutely have no idea, make an
educated guess of the liver.
5. What cells of the pancreas secrete glucagon?
a. Islets of Langerhans
b. Alpha cells
c. Beta cells
d. Delta cells
e. Gamma cells
The pancreas is both an endocrine and exocrine organ.
The endocrine portion of the pancreas is housed in the islets
of Langerhans. Within the islets, there are several cell types.
The alpha cells secrete glucagon. The beta cells secrete
insulin. The delta cells secrete somatostain. The gamma cells
secrete pancreatic polypeptide.
The acini is the exocrine portion of the pancreas.
6. What are the connection between the cystic duct and
liver?
a. Rokitansky-Aschoff sinuses
b. Ducts of Luschka
c. Duct of Wirsung
d. Ampulla of Vater
e. Sphincter of Oddi
Rokitansky-Aschoff sinuses are divertiuclae of the mucosa
of the gallbladder. The small bile ducts which connec
between the cystic duct and liver are the ducts of Luschka
The duct of Wirsung is the pancreatic duct. The opening of
the pancreatic duct into the duodenum is at the ampulla of
Vater. The valves which regulates the flow of bile into the
small intestine is the sphincter of Oddi.
7. Which of the following is NOT a function of the
liver?
a. Conversion of glucose into glycogen
b. Storage of glycogen
c. Storage of bile
d. Storage of fat soluble vitamins
e. Cholesterol synthesis
The liver performs many, many functions. Estimates range
at over 500 different functions for the liver.
Glucose is converted to glycogen in the liver. Glycogen is
stored in the liver. The liver stores of fat soluble vitamins
(A, D, E, K). Cholesterol is synthesized in the liver.

Once bile is produced by the liver, it is stored in the

gallbladder.

Histology hint from Sarah Bellham: If ever asked where a

process occurs, and you absolutely have no idea, make an
educated guess of the liver.

8. What cells of the pancreas secrete pancreatic

polypeptide?
a. Islets of Langerhans
b. Alpha cells
c. Beta cells
d. Delta cells
e. Gamma cells

The pancreas is both an endocrine and exocrine organ.

The endocrine portion of the pancreas is housed in the islets

of Langerhans. Within the islets, there are several cell types.
The alpha cells secrete glucagon. The beta cells secrete
insulin. The delta cells secrete somatostain. The gamma cells
secrete pancreatic polypeptide.

The acini is the exocrine portion of the pancreas.