COURSE TITLE: PRINCIPLES OF GENETICS

COURSE DESCRIPTION: Mechanisms of heredity and variation, cytogenetics, mutation, nature of

genes, population genetics and evolutionary genetics, biometrical procedures
COURSE CODE: CC7-BIO1
CREDIT UNITS: 3 units (2 hours lecture and 3 hour laboratory)
PREREQUISITIES: CC2
LINK TO PROGRAM OUTCOMES: Course Program Outcomes
h. Apply the scientific methods in knowledge generation and Outcomes
knowledge application; h i j k l
i. Understand and apply the concepts of agricultural productivity
and sustainability in the context the national, regional, and global 1 I I I I I
developments;
j. Engage in agricultural production and post-production activities; 2 I P I P P
k. Promote sound agricultural technologies to various clients and
in the manpower 3 P P P P P
development for agriculture;
4 P P P P P
l. Employ relevant tools in information technology in solving
agriculture-related problems; Legend (for program outcomes):
I- Introduced concepts/ principle
P- Practiced with supervision
D- Demonstrated across different
settings with minimal supervision
COURSE OUTCOMES: At the end of the semester, the students should be able to:
1. The nature, expression, and regulation of genes in the individual.
2. The mechanisms of genetic transmissions.
3. The sources of variation in individuals and populations.
4. The behavior of genes in populations.
COURSE OUTLINES:
Week Learning outcomes Topics Teaching/Learning Assessment
Activities
Week Enumerate and I. Genetics: The Science of Quizzes
1, discuss the scientist Heredity and Variation Lecture discussion Term exam
contributed in the A. Definition of Genetics Power point Graded
field of genetics and B. The Beginnings of Genetics presentation
application of C. The Scope of Genetics
genetics in plants D. Applications of Genetics
and animals
Week Explain II. The Chromosomal Basis of Quizzes
3 chromosome Heredity Lecture discussion Term exam
behavior and A. The Cell Power point Graded
changes in B. The Chromosome Structure presentation
chromosome C. Cell Division: Mitosis, Meiosis
structure and D. Life cycles: Germinal or
number as a cell Gametic Meiosis, Intermediary or
progresses through sporic Meiosis, Initial or Zygotic
a cell cycle, meiosis Meiosis
I and meiosis
Week Identify and discuss III. Gene Segregation and Lecture discussion Quizzes
4, 5, 6 Mendel’s principles Interaction Power point Term exam
of inheritance and A. Law of Segregation presentation Graded
apply these to B. Law of Independent
problems of Assortment
inheritance C. Segregation and Assortment
in Haploid Organisms
D. Dominance Relationships:
Complete Dominance, Incomplete
Dominance, Overdominance, Co-
dominance
E. Multiple Alleles
F. Lethal Genes: Recessive
Lethal, Dominant Lethal
Modifier Genes
G. Gene Interactions: Novel
Phenotypes, Recessive Epistasis,
 Dominant Epistasis,
Complementary Genes, Duplicate
Genes
H. Pseudoalleles
I. Environmental Influence on
Gene Expression: Definition of
Terms, External Environment,
Internal Environment
J. Twin Studies: Concordance
and Discordance
K. Probability and Statistical
Testing: Level of Significance, Chi-
Square Test, Binomial Distribution
Week Identify and discuss IV. Linkage and Recombination Quizzes
7, effect of linkage and A. Definition of Linkage Lecture discussion Term exam
independent B. Determination of Linkage Power point Graded
assortment on C. Chromosome Mapping presentation
genetic outcomes D. Factors Affecting
and assess data to Recombination Frequencies
determine if genes E. Sex Determination
are linked or on F. Sex Linkage
separate
chromosome
Week Describe how gene V. Chemical Basis of Heredity Lecture discussion Quizzes
8,9 expression and A. The Concept of the Gene Power point Term exam
protein expression B. Chemical Composition of the presentation Graded
produce a Chromosome
phenotype and C. DNA as the Genetic Material
discuss the benefits D. Chemical Composition of the
associated with a DNA
better understanding E. Molecular Structure of DNA
of genes F. Organization of DNA in
andgenomes Chromosomes: Prokaryotic
Chromosome, Eukaryotic
Chromosome
G. Replication or Synthesis of
DNA: Mode of Replication, Process
of Replication, Conformation of
DNA Replication
H. Error Correction in DNA
Replication
I. RNA as the genetic Material
Week Identify and discuss VI. Gene Function: Proteins and Lecture discussion Quizzes
10, 11 the function of gene Enzymes Power point Term exam
as a protein and A. Genetic Control of Proteins: presentation Graded
enzymes Gene-Enzyme Relationship: Inborn
Error of Metabolism One-Gene
Enzyme Hypothesis, Protein
Structure, Colinearity of DNA
Proteins
B. Protein Synthesis: Central
Dogma of Molecular Biology,
General Information Transfers,
Interrupted Genes
C. The Genetic Code: The
Triplet Code, Universality of the
Genetic Code
D. Regulation of Gene Action: in
Prokaryotes
Week Explain how VII. Mutation Lecture discussion Quiz
12 mutations occur in A. Variation in Genome Power point Group
the genome and the Structure or Numerical Changes of presentation discussion
differences between the Chromosome Laboratory
spontaneous and B. Changes in Chromosome
induced mutations Structure or Chromosomal
and germline and Abberations
somatic mutations C. Gene Mutations
D. Reverse Mutations
 E. Mutagenic Agents
F. Evolutionary Significance of
Mutations
Week Explain and VIII. Delayed Chromosomal and Lecture discussion Quiz
13 describe how ties Extrachromosomal Inheritance Power point Group
between maternal A. Delayed Chromosomal presentation discussion
parent and offspring Inheritance Laboratory
play a big role in B. Extrachromosomal
delayed Inheritance: Cytoplasmic
chromosomal Inheritance, Cytoplasmic Particles,
inheritance Chloroplast, Mitochondria
C. Plasmids of Extracellular
Origin: Infective Heredity Episomes
D. Criteria for
Extrachromosomal Inheritance

Week Explain why IX. Quantitative Inheritance Lecture discussion Quiz

14 inheritance patterns A. Inheritance of Quantitative Power point Group
are often more Characters: Multiple Genes presentation discussion
complex than B. Analysis of Quantitative Laboratory
expected under Characteristics
simple Mendelian C. Components of Phenotypic
genetics Variance
D. Heritability: Heritability in the
Narrow Sense, Heritability in the
Broad Sense
Week Explain and X. Genes in Populations Lecture discussion Quiz
15, 16, describe the A. Population Genetics Power point Group
relationship between B. Gene Frequencies and presentation discussion
genotype frequency Equilibrium: Gene Frequencies, Laboratory
and allele frequency, Gene Pool, Model-system for
as described by the Population Stability (Hardy-
Hardy-Weinberg Weinberg Law)
equation C. Changes in Gene
Frequencies: Mutation Selection
D. Race and Species
Formation: The Concept of Races,
The Concept of Species
Week Describe the nature XI. Genetics and Man Lecture discussion Quiz
17 of chromosomal A. Cytogenetics Power point Group
abnormalities in B. Inborn Error Metabolism presentation discussion
clinical syndromes C. Behavioral Genetics Laboratory
associated with
cytogenetic
disorders and the
nature of
chromosomal
Week Describe the XII. Genetic Engineering and Lecture discussion Quiz
18 concept of Biotechnology Power point Final
recombinant DNA A. Recombinant DNA/Genetic presentation examination
technology orEngineering Laboratory
genetic engineering
B. Applications of Genetic
Engineering
SUGGESTED LEARNING RESOURCE

LCD/ or TV, monitor, laptop, lecture, manual/ or syllabus