WHAT IS IN THIS treatment of signs of physical • any of the ingredients listed at
male characteristics as described the end of this leaflet. LEAFLET above. Diane-35 ED contains a Some of the symptoms of an This leaflet answers some common progestogen and an oestrogen allergic reaction may include: questions about Diane-35 ED. It hormone, and therefore works • shortness of breath does not contain all the available similarly to the combined oral • wheezing or difficulty in information. It does not take the contraceptive birth control pill, breathing place of talking to your doctor or also known as ‘the Pill’. It should • swelling of the face, lips, pharmacist. not be used in combination with tongue or other parts of the another hormonal contraceptive. body All medicines have risks and • rash, itching or hives on the benefits. Your doctor While taking Diane-35 ED you skin. has weighed the risks of you taking may also experience the Diane-35 ED against the benefits following benefits: Diane-35 ED is not for use in they expect it will have for you. • more regular and lighter men. periods – potentially resulting Do not take Diane-35 ED if you If you have any concerns, or are in a decreased risk in anaemia are taking antiviral medicines unsure about taking this (iron deficiency) which contain ombitasvir, medicine, ask your doctor or • a decrease in period pain paritaprevir, or dasabuvir, and pharmacist for more advice. • reduction of greasiness in skin combinations of these. These and hair. antiviral medicines are used to Keep this leaflet with the Some conditions such as pelvic treat chronic (long-term) hepatitis medicine. You may need to read it inflammatory disease, ovarian C (an infectious disease that again. cysts, ectopic pregnancy (where affects the liver, caused by the the foetus is carried outside of hepatitis C virus). WHAT DIANE-35 ED IS your womb), lumpy breasts and USED FOR cancer of the uterus (womb) and Do not take Diane-35 ED if you ovaries may be less common in Diane-35 ED is used for the women taking Diane-35 ED. have, or have had, a blood clot treatment of signs of physical in: Ask your doctor if you have male characteristics caused by the any questions about why this • the blood vessels of the legs male sex hormone, androgen, (deep vein thrombosis - DVT) medicine has been prescribed produced by in women in small for you. • the lungs (pulmonary amounts (androgenisation), such Your doctor may have prescribed embolism - PE) as: it for another reason. • the heart (heart attack) • severe acne where other • the brain (stroke) treatments have not been BEFORE YOU TAKE • other parts of the body. successful DIANE-35 ED • for excessive growth of facial Do not take Diane-35 ED if you or body hair (known as When you must not take are concerned about or have an hirsutism) of a mild to it increased risk of blood clots. moderate degree, where no Do not take Diane-35 ED if you underlying cause has been Blood clots are rare. Very have an allergy to: found. occasionally blood clots may • cyproterone acetate and/or Diane-35 ED can also be used as a cause serious permanent ethinyloestradiol (the active contraceptive to prevent pregnancy disability and may even be fatal. ingredients in Diane-35 ED) in women who are taking it for the
1801 DIANE-35® ED CMI 1
All combined oral contraceptive • high risk of blood clots due to pills, including Diane-35 ED, conditions such as diabetes Do not take this medicine if the increase the risk of having a blood with blood vessel damage, packaging is torn or shows clot. However, the risk of having a severe high blood pressure or signs of tampering. blood clot when taking Diane-35 severe high or low level of fats If the packaging is damaged, ED is less than the risk of having a in your blood return it to your pharmacist for blood clot during pregnancy. • pancreatitis (an inflammation disposal. of the pancreas) associated Do not take Diane-35 ED if you with high levels of fatty If you are not sure whether you are concerned about an substances in your blood should start taking this increased risk of blood clots • severe liver disease and your medicine, talk to your doctor. because of age or smoking. liver function has not returned to normal Before you start to take it The risk of having a heart attack or • cancer that may grow under the Tell your doctor if you have stroke increases as you get older. It influence of sex hormones (e.g. allergies to any other also increases if you smoke. of the breast or the genital medicines, foods, preservatives You should stop smoking when organs) or dyes. taking Diane-35 ED, especially if • a benign or malignant liver you are older than 35 years of age. tumour Tell your doctor if: • unexplained vaginal bleeding. • you smoke Do not take Diane-35 ED if you • you, or anyone in your have, or have had: If any of these conditions immediate family has had • blood clots in your legs appear for the first time while blood clots in the legs (DVT), • any blood clotting disorders using Diane-35 ED, stop taking or lungs (PE), a heart attack, such as Protein C deficiency, it at once and tell your doctor. a stroke, breast cancer or high Protein S deficiency, Leiden In the meantime use non- cholesterol. Factor V mutation, hormonal (barrier) methods of Antithrombin III deficiency contraception (such as Tell your doctor if you have or or other inherited blood condoms or a diaphragm). have had any of the following clotting conditions. medical conditions: A confirmed blood test Do not take Diane-35 ED if you • diabetes showing: are using another hormonal • high blood pressure o increased levels of contraceptive. • heart valve disorders or certain homocysteine heart rhythm disorders o antiphospholipid Do not take this medicine if you • migraine antibodies (APLAs) e.g. are pregnant or think you anticardiolipin-antibodies • cancer might be pregnant. • polycystic ovary syndrome, a and lupus anticoagulant. These may increase your hormonal condition which can Do not breast-feed if you are cause menstrual irregularity risk for blood clots or taking this medicine. pregnancy losses and excess hair growth (miscarriage). • hyperhomocysteinaemia, a Do not give this medicine to a • major surgery after which you condition characterised by high child. have not been able to move levels of the amino acid around for a period of time homocysteine in the blood Do not take this medicine after • angina (chest pain) • severe high or low levels of the expiry date printed on the • a mini-stroke (also known as fats in the blood. pack and blister. The expiry TIA or transient ischaemic date is printed on the carton and attack) Ask your doctor to check if on each blister after “EXP” (e.g. you: • migraine, where you have also 11 18 refers to November 2018). had problems with seeing, The expiry date refers to the last • are overweight speaking or had weakness or day of that month. If it has • have any hereditary or acquired numbness in any part of your expired return it to your conditions that may make it body pharmacist for disposal. more likely for you to get blood clots
1801 DIANE-35® ED CMI 2
• have high cholesterol or If you have an intolerance to medicines used to relax the triglycerides some sugars, tell your doctor body • have liver disease before you start taking Diane-35 • theophylline, a medicine that • have jaundice (yellowing of the ED. helps with breathing skin) and/or pruritus (itching of • herbal medicines containing St the skin) related to cholestasis If you have not told your John’s Wort (condition in which the flow of doctor about any of the above, • grapefruit juice. bile from the liver stops or tell him/her before you start slows) taking Diane-35 ED. These medicines may be affected • have gall bladder disease by Diane-35 ED, or may affect • have Crohn’s disease or Taking other medicines how well it works. Your doctor ulcerative colitis Tell your doctor or pharmacist may need to alter the dose of (chronic inflammatory bowel if you are taking any other your medicine or prescribe a disease) medicines, including any that different medicine. • have systemic lupus you get without a prescription erythematosus (SLE – a disease from your pharmacy, Some medicines affecting the skin all over the supermarket or health food • can have an influence on the body) shop. blood levels of Diane-35 ED • have haemolytic uraemic • can make it less effective in syndrome (HUS – a disorder of Some medicines and Diane-35 preventing pregnancy or blood coagulation causing failure ED may interfere with each • can cause unexpected bleeding. of the kidneys) other. These include: • have sickle cell disease • medicines used to treat You may need to use additional • have a condition that occurred tuberculosis such as rifampicin, barrier methods of for the first time, or worsened rifabutin contraception (such as during pregnancy or previous • medicines used to treat condoms or a diaphragm) use of sex hormones (e.g. epilepsy such as phenytoin, while you are taking any of hearing loss, a metabolic disease primidone, barbiturates (e.g. these medicines with Diane-35 called porphyria, a skin disease phenobarbitone), ED and for some time after called herpes gestationis, a carbamazepine, oxcarbazepine, stopping them. neurological disease called topiramate, felbamate, Sydenham’s chorea) lamotrigine Your doctor will be able to tell • have chloasma (yellowish-brown • medicines used to treat HIV, you how long you will need to pigmentation patches on the such as ritonavir or nevirapine use additional contraceptive skin, particularly of the face) – if • some medicines used to treat methods. so, avoid exposure to the sun or Hepatitis C Virus (HCV) such ultraviolet radiation as boceprevir, telaprevir Your doctor and pharmacist have • have hereditary angio-oedema – • macrolide antibiotics (e.g. more information on medicines you should see your doctor clarithromycin, erythromycin) that you need to be careful with immediately if you experience • medicines used to treat fungal or avoid while taking this symptoms of angio-oedema, infections, such medicine. such as swollen face, tongue as ketoconazole and and/or pharynx and/or difficulty griseofulvin swallowing, or hives together • cyclosporin, an HOW TO TAKE with difficulty in breathing. immunosuppressant medicine DIANE-35 ED • medicines used to treat high If any of the above conditions blood pressure, chest pain appear for the first time, recur, and/or irregular heartbeats such Follow all directions given to or worsen while taking Diane-35 as diltiazem, verapamil you by your doctor or pharmacist carefully. ED, you should tell your doctor. • etoricoxib, an anti- They may differ from the inflammatory medicine used to Diane-35 ED contains lactose. information contained in this treat pain leaflet. • tizanidine, melatonin or midazolam which are
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If you do not understand the of tablet-taking when having the day that your implant or IUS instructions on the pack ask intercourse. is removed. your doctor or pharmacist for help. Your doctor will advise you You must also use additional when to start if you: barrier contraceptive How to take it • are taking Diane-35 ED after precautions (e.g. condoms or a Take one tablet daily at about the having a baby diaphragm) for the first same time every day. You must • have had a miscarriage or an 14 days of tablet-taking take Diane-35 ED every day abortion. when having intercourse. regardless of how often you have sex. This will also help you Changing from another How long to take Diane- remember when to take it. contraceptive 35 ED Changing from a combined You may have to take Diane-35 Swallow the tablet whole with a oral contraceptive: ED for at least 6 months before full glass of water. It does not you see an improvement in your Start taking Diane-35 ED on the matter if you take it before or after condition. The length of day after taking the last active food. treatment depends on the severity tablet in your previous Pill pack. Bleeding may not occur until the of the condition and how well it Each blister pack is marked with responds to treatment. end of the first pack of Diane- the day of the week. 35ED. You may be advised by your Take your first tablet from the doctor to stop Diane-35 ED 3 to If you are not sure which were red area on the blister pack 4 months after your symptoms the active/inactive tablets in corresponding to the day of the have completely resolved. your previous Pill pack, ask week. your doctor or pharmacist. Your previous Pill pack may You should have regular check- Follow the direction of the ups with your doctor to have different colour tablets to arrows on the blister pack until determine how long to keep those of Diane-35 ED. all the tablets have been taken. taking Diane-35 ED. Changing from a vaginal ring: A period should begin 2-3 days Stopping Diane-35 ED after starting to take the white Start taking Diane-35 ED on the day of removal of the last vaginal You can stop taking Diane-35 inactive tablets (last row) and may ED at any time. not have finished before the next ring. pack is started. It is possible that the original Changing from a progestogen- only pill (‘minipill’): condition may recur once Diane- Always start a new blister pack 35 ED is stopped. Do not start on the same day of the week as Stop taking the minipill on any taking Diane-35 ED again your previous pack. day and start taking Diane-35 ED without seeing your doctor first. at the same time the day after you Taking Diane-35 ED for the took your last minipill. If you do not wish to fall first time pregnant, you should use You must also use additional If you are starting Diane-35 ED additional barrier contraceptive barrier contraceptive after a natural cycle, and you have precautions (e.g. condoms or a precautions (e.g. condoms or a not used a hormonal contraceptive diaphragm) when you stop taking diaphragm) for the first 14 in the past month, start on the first Diane-35 ED. days of tablet-taking day of your period, i.e. on the first when having intercourse. If you are considering becoming day of your menstrual bleeding. pregnant, it is recommended that Changing from a progestogen You must also use additional you begin taking a vitamin only injection, implant or barrier contraceptive supplement containing folic acid. intrauterine system (IUS): precautions (e.g. condoms or a It is best that you start taking cap or diaphragm plus Start taking Diane-35 ED when folic acid tablets before you stop spermicide) for the first 14 days your next injection is due, or on taking Diane-35 ED and not stop
1801 DIANE-35® ED CMI 4
until your doctor advises this. Ask you may not have a period until “Summary of advice if you your doctor or pharmacist about the end of the beige active tablets missed an active tablet more suitable supplements. It is both of the second pack. You may than 12 hours ago”. safe and recommended that you have spotting or breakthrough take folic acid during pregnancy. bleeding on tablet-taking days. Ask your doctor or pharmacist to answer any questions you If you forget to take Diane- If you have been taking the may have. 35 ED beige active tablets for less than 7 days and miss a beige active If you take too much If you miss a tablet and take the tablet, take the missed tablet as (overdose) missing tablet within 12 hours of soon as you remember, then go Immediately telephone your missing it, you should still be back to taking your medicine doctor or the Poisons protected against pregnancy. as you would normally, even if Information Centre (Australia: this means taking two tablets in 13 11 26 or New Zealand: 0800 If you are more than 12 hours late one day at the same time. In poison or 0800 764 766) follow these detailed instructions: addition, you must also use for advice, or go to the additional barrier Accident and Emergency For Diane-35 ED to be most contraceptive precautions (e.g. Department at your effective, beige active tablets condoms or a diaphragm) for nearest hospital, if you think need to be taken uninterrupted the next 7 days. that you or anyone else may for 7 days. have taken too much Diane-35 If you have had sexual ED. Do this even if there are no If you have been taking the beige intercourse in the preceding 7 signs of discomfort or active tablets for 7 uninterrupted days, there is a possibility of poisoning. You may need days and miss a beige active pregnancy and you may need medical attention. tablet, take the missed tablet as emergency contraception. You soon as you remember, then go should discuss this with your If you take several beige active back to taking your medicine as doctor or pharmacist. tablets at once, you may feel sick you would normally, even if this or vomit or may bleed from the means taking two tablets in one If you forget to take more than vagina. Even girls who have not day at the same time. You will one beige active tablet, seek yet started to menstruate but have not need to use additional barrier advice from your doctor or accidentally taken this medicine contraceptive precautions. pharmacist about what to do. may experience such bleeding.
The chance of pregnancy after If you have had sexual
missing a beige active tablet intercourse in the week before missing your tablets, there is a WHILE YOU ARE depends on when you missed the tablet. There is a higher risk of possibility of becoming pregnant. TAKING DIANE-35 ED becoming pregnant if you miss a You should discuss this with beige tablet at the beginning or your doctor or pharmacist. Things you must do end of a pack. Tell any other doctors, dentists, If you miss a white inactive and pharmacists who treat you If after taking your missed tablet tablet, you do not need to take that you are taking this you have less than 7 days of them later because they do not medicine. beige active tablets left in a row, contain any active ingredients. you should finish the active However, it is important that you If you are about to have any tablets in your pack but skip the discard the missed white tablet(s) blood tests, tell your doctor white inactive tablets and start a to make sure that the number of that you are taking this new pack with the beige active days between taking active medicine. It may interfere with tablets corresponding to the tablets is not increased as this the results of some tests. correct day of the week. would increase the risk of pregnancy. Continue with the Have regular check-ups with This is the best way to maintain next tablet at the usual time. your doctor. When you are contraceptive protection. However, Please see the diagram at the taking Diane-35ED, your doctor end of this leaflet entitled
1801 DIANE-35® ED CMI 5
will tell you to return for regular vision which can progress to particularly in women with check-ups, including getting a loss of vision other risk factors. Consult your Cervical Screening Test. Your • sudden, severe or prolonged doctor if you plan to air travel for doctor will advise how often you headache with no known cause greater than 4 hours. need a Cervical Screening Test. A • loss of consciousness or Cervical Screening Test can detect fainting with or without Consult your doctor if you abnormal cells lining the cervix. seizure. develop high blood pressure Sometimes abnormal cells can • pain, discomfort, pressure, while taking Diane-35 ED – you progress to cancer. heaviness, sensation of may be told to stop taking it. squeezing or fullness in the If you are about to start on any chest arm, or below the If you become pregnant while new medicine, remind your breastbone taking this medicine, tell your doctor and pharmacist that you • discomfort radiating to the doctor immediately. are taking Diane-35 ED. back, jaw, throat, arm, stomach • feeling of being full, having If you vomit within 3-4 hours Stop taking Diane-35 ED and see indigestion or choking or have severe diarrhoea after your doctor immediately or go to • sweating, nausea, vomiting taking a beige active tablet, the the Emergency Department at • extreme weakness and anxiety active ingredients may not have your nearest hospital if you been completely absorbed. This notice the following signs: is like missing a tablet. Follow If you are going to have • one-sided swelling of the leg surgery, tell the surgeon or the advice for missed tablets. and/or foot or along a vein in the anaesthetist beforehand that leg If you have unexpected you are taking Diane-35 ED. • pain or tenderness in the leg The risk of having blood clots is bleeding and it continues, which may be felt only when temporarily increased as a result becomes heavy, or occurs standing or walking again, tell your doctor. When of major surgery, any surgery to • increased warmth in the affected the legs or pelvis, neurosurgery taking these tablets for the first leg; red or discoloured skin on few months, you can have or major trauma. In women who the leg irregular vaginal bleeding take Diane-35 ED, the risk may • sudden onset of unexplained be higher. (spotting or breakthrough shortness of breath or rapid bleeding) between your periods. breathing You may need to use sanitary In women at risk of prolonged • sudden coughing or coughing up products, but continue to take immobilisation (including major of blood your tablets as normal. Irregular surgery, any surgery to the legs • sharp chest pain or sudden vaginal bleeding usually stops or pelvis, neurosurgery, or major severe pain in the chest which once your body has adjusted to trauma), your doctor may tell you may increase with deep Diane-35 ED, usually after about to stop taking (in the case of breathing 3 months. elective surgery at least four • severe light headedness or weeks in advance) and not dizziness resume until two weeks after If you have missed a period, but you have taken all your • rapid or irregular heartbeat complete remobilisation. Another tablets, it is unlikely that • sudden pain, swelling and slight method of contraception should be used to avoid unintentional you are pregnant, as long as: blue discoloration of an pregnancy. Your doctor may • you have taken the beige active extremity tablets at the right time • sudden numbness or weakness of prescribe other treatment (e.g. treatment for blood clots) if • you have not been taking the face, arm or leg, especially Diane-35ED has not been medicine(s) that may interfere on one side of the body with Diane-35 ED. • sudden trouble walking, discontinued in advance. • you have not vomited or had dizziness, loss of balance or Other risk factors for blood severe diarrhoea during this coordination clotting include temporary cycle. • sudden confusion, slurred speech or aphasia; sudden partial or immobilisation including air travel of greater than 4 hours, If this is so, continue to take complete loss of vision, double Diane-35 ED as usual. If you vision, painless blurring of
1801 DIANE-35® ED CMI 6
have any concerns consult your All medicines can have side face, arm or leg, especially on doctor or pharmacist. effects. Sometimes they are one side of the body serious, most of the time they are • sudden trouble walking, If you miss your period twice in not. You may need medical dizziness, loss of balance or a row, you may be pregnant even attention if you get some of the coordination if you have taken Diane-35 ED side effects. • severe, sudden stomach pains correctly. Stop taking Diane-35 • a fainting attack or you ED and seek advice from your Do not be alarmed by the collapse doctor. You must use a non- following lists of side effects. • unusual headaches or hormonal method of You may not experience any of migraines that are worse than contraception, (such as condoms them. usual or a diaphragm) until your • sudden problems with doctor rules out pregnancy. Ask your doctor or pharmacist speaking, seeing or to answer any questions you understanding what people are Diane-35 ED will not protect you may have. saying to you. from HIV-AIDS or any other The side effects listed above are sexually transmitted infections The following list includes the possible signs of a blood clot (STIs), such as chlamydia, genital more common side effects of (thrombosis). herpes, genital warts, gonorrhoea, Diane-35 ED. These are usually • jaundice (yellowing skin or hepatitis B, human papilloma virus mild and lessen with time. yellowing eyes) and syphilis. • you cough up blood If you notice any of the • breast lumps To protect yourself from STIs, following side effects and they • unexplained vaginal bleeding. you will need to use additional worry you, tell your doctor or barrier contraceptives pharmacist: Tell your doctor or pharmacist (e.g. condoms). • nausea if you notice anything that is • stomach pain or discomfort making you feel unwell. Things you must not do • changes in weight Other side effects not listed Do not take Diane-35 ED to treat • headache, including migraines above may also occur in some any other conditions, unless your • mood changes, including people. doctor tells you to. depression • breast tenderness or pain. Blood clots and Diane-35 Do not give your medicine to ED anyone else. The following list includes very Blood clots may block blood serious but rare side effects. You Do not stop taking your vessels in your body. This type of may need urgent medical medicine or change the dosage blood clot is also called attention or hospitalisation. without checking with your thrombosis. doctor. You may become pregnant If you experience any of the if you are not using any other Blood clots sometimes occur in following, tell your doctor contraceptive and you stop taking the deep veins of the legs. If a immediately, or go to the Diane-35 ED, or do not take a blood clot breaks away from the Emergency Department at tablet every day. veins where it has formed, it may your nearest hospital: reach and block the blood vessels • pain in the chest, arm, or below of the lungs, causing pulmonary SIDE EFFECTS the breastbone embolism. • pain or discomfort that goes to Tell your doctor or pharmacist your back as soon as possible if you do not Blood clots can also occur in the • breathlessness and/or difficulty blood vessels of the heart feel well while you are taking Diane-35 ED. breathing (causing a heart attack) or the • swelling, pain or tenderness of brain (causing a stroke). This medicine helps most women, one leg or along a vein in the but it may have unwanted side leg Blood clots are a rare occurrence effects in some women. • sudden weakness, numbness or and can develop whether or not bad ‘pins and needles’ of the you are taking Diane-35 ED.
1801 DIANE-35® ED CMI 7
They can also happen during contact your doctor if you feel date has passed, ask your pregnancy. The risk of having any lumps. pharmacist what to do with any blood clots is higher in Diane-35 medicine that is left over. ED users than in non users, but not In rare cases benign liver as high as during pregnancy. tumours and, even more rarely, Return any unused medicine to malignant liver tumours have your pharmacist. The risk of a blood clot is highest been reported in users of the Pill. during the first year of taking These tumours may lead to PRODUCT Diane-35 ED for the first time, or internal bleeding. after having a break from Diane-35 Contact your doctor DESCRIPTION ED for 4 weeks or more. immediately if you have severe pain in your abdomen. What it looks like If you notice possible signs of a Diane-35 ED active tablets are blood clots, stop taking Diane-35 Cervical cancer has been beige and round. ED and consult your doctor reported to occur more often in immediately. To prevent women who have been taking the Diane-35 ED inactive tablets are pregnancy, you must also use Pill for a long time. This finding white and round. additional barrier contraceptive may not be caused by the Pill, precautions (e.g. condoms or a but may be related to sexual Diane-35 ED comes in a box diaphragm). behaviour and other factors. containing either 1 or 3 blister packs. Each blister pack contains If you are concerned about an AFTER TAKING 21 beige active tablets and 7 increased risk of blood clots white inactive tablets. while on Diane-35 ED, speak to DIANE-35 ED your doctor. Storage Ingredients Keep your tablets in the blister Each beige active tablet Cancer and Diane-35 ED pack until it is time to take contains: Diane-35 ED contains a them. If you take the tablets out Active ingredients: progestogen and an oestrogen of the pack they may not keep • 2 mg of cyproterone acetate hormone, and therefore works well. • 35 micrograms of similarly to the combined oral ethinyloestradiol contraceptive birth control pill, the Keep your tablets in a cool dry Inactive ingredients: Pill. place where the temperature • lactose stays below 25°C. • maize starch Breast cancer has been diagnosed • povidone slightly more often in women who Do not store your tablets or any other medicine in the • magnesium stearate take the Pill than in women of the bathroom, near a sink, or on a • sucrose same age who do not take the Pill. window-sill. Do not leave • macrogol 6000 This slight increase in the numbers medication in the car. • calcium carbonate of breast cancer diagnoses Heat and damp can destroy some • purified talc gradually disappears during the medicines. • glycerol course of the 10 years after women • titanium dioxide stop taking the Pill. Keep Diane-35 ED where • iron oxide yellow children cannot reach it. • glycol montanate It is not known whether the A locked cupboard at least one- • purified water difference is caused by the Pill. It and-a-half metres above the may be that these women were ground is a good place to store Each white inactive tablet examined more often, so that the medicines. contains: breast cancer was noticed earlier. • lactose Disposal • maize starch It is important that you check If your doctor tells you to stop • povidone your breasts regularly and taking this medicine or the expiry • magnesium stearate
Summary of advice if you missed an active tablet more than 12 hours ago.
No Did you No Take the tablet missed AND use extra
have sex in barrier precaution for 7 days. If there are the 7 days fewer than 7 beige active tablets left in before the pack, finish the beige active tablets Before missing missing the and go straight to the beige active tablets your tablet, did tablet? of the next pack. This means you skip the you take beige white inactive tablets. active tablets for the previous Yes See your Doctor or Pharmacist for advice. 7 days? No Take the tablet you missed AND complete Yes Does your taking the beige active tablets. Skip pack still the white inactive tablets. Start your next have 7 pack with beige active tablets. active beige tablets in a Yes Take the tablet you missed AND row to complete the pack as normal. follow?
Etiological Study of Autism and Assessment by ISAA (Indian Scale For Assessment of Autism) For Diagnosis of Autism Spectrum Disorder in Children at Hi Tech Medical College and Hospital, Bhubaneswar