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22 Respiration
(1) ______________ (呼吸作用) is the process by which organisms release (2) ______________
from food through the controlled (3) _______________ breakdown of food.
(4) _______________ is the most common substrate for respiration.
During respiration, glucose is broken down into (5) _______________ _______________ and
(6) _______________ through a series of chemical reactions in a gradual manner. The
reactions are controlled by (7) _______________.
In each reaction, chemical energy is released. About 45% is stored in the energy carrier
(8) _______________, while the remaining 55% is lost as (9) ______________.
Overall equation of respiration:
enzymes
glucose + oxygen (10) ____________ ____________ + water + energy (ATP)
During respiration, some of the energy released is used to form (11) _______________ by
combining a phosphate (P) with ADP. This process is called (12) _______________ (磷酸化).
ATP acts as an (13) _______________ _______________ in the cell in which it is made. It can
be readily broken down into ADP and phosphate with the release of a (14) _______________
(small / large) amount of energy. The ADP and phosphate released can be (15) ______________
to form more ATP during respiration.
ATP
ADP + P
Both types of respiration start with the same step which occurs in the (1) _______________ of
a cell. For aerobic respiration, the remaining steps occur in the (2) _______________.
Structure of a mitochondrion:
(3) _______________
membrane
intermembrane
space
(7) _______________ cells such as muscle cells, fat cells, liver cells and sperms contain a lot
of mitochondria.
Aerobic respiration takes place in the presence of (1) _______________. It occurs in three
main stages: (2) _______________ (糖酵解), (3) _______________ _______________
(克雷伯氏循環) and (4) _______________ _______________ (氧化磷酸化).
Glycolysis occurs in the (5) _______________. It does not require (6) _______________. It
involves two main steps catalysed by enzymes in the (7) _______________.
4 ADP + 4 P 4 ATP
Breakdown of glucose Oxidation of triose
to triose phosphate phosphate to pyruvate
▲ An overview of glycolysis
NAD NADH
CO2 coenzyme A
For each molecule of glucose that undergoes glycolysis, (29) _______________ molecules of
acetyl-CoA are formed. Coenzyme A acts as a (30) _______________ molecule which carries
the acetyl group into the Krebs cycle.
The Krebs cycle occurs in the (31) _______________ _______________. It involves two main
steps catalysed by specific (32) _______________ in the matrix.
coenzyme A
Combination of
acetyl-CoA with
4-C compound
Regeneration of
4-C compound
FADH
2 CO2
FAD
3 NAD
3 NADH
ATP ADP + P
The final stage of aerobic respiration occurs on the (43) _______________ (outer / inner)
membrane of the mitochondrion. It is called oxidative phosphorylation because the energy
for forming ATP by (44) _______________ comes from (45) _______________ of NADH and
FADH.
oxidation + –
NADH NAD + H + e
oxidation + –
FADH FAD + H + e
accepted by O2 H2O
▲ Oxidation of NADH and FADH and the fate of hydrogen ions and
electrons released
NADH and FADH formed in glycolysis and the Krebs cycle lose their (46) _______________
and are (47) _______________ to NAD and FAD respectively. NAD and FAD are
regenerated. They can accept (48) _______________ in glycolysis and the Krebs cycle again.
The hydrogen atoms split into (49) _______________ ions and (50) _______________.
The electrons take part in a series of (51) _______________ reactions catalysed by enzymes
embedded in the (52) _______________ (outer / inner) membrane of mitochondria. Energy is
released to form (53) _______________ in the reactions.
The hydrogen ions and electrons are eventually transferred to the final electron acceptor,
(54) _______________, to form (55) _______________.
Note: Oxidation of each NADH forms 3 ATP. Oxidation of each FADH forms 2 ATP.
2 ATP 2
Glycolysis
2 NADH 2×3= 6
Conversion of pyruvate
2 NADH 2×3= 6
to acetyl-CoA
2 ATP 2
Krebs cycle 6 NADH 6 × 3 = 18
2 FADH 2×2= 4
2 ATP 2 NADH
2 pyruvate
2 ATP
4 CO2 2 FADH
inner
membrane of 34 Oxidative phosphorylation H2O
mitochondria ATP
O2
Go to
Practical 22.1 Investigation of carbon dioxide production in germinating seeds
(Book 3, p. 22-17; Practical Workbook for SBA 3 • 4, p. 22-1)
Practical 22.2 Investigation of carbon dioxide production in a living mouse
(Book 3, p. 22-18; Practical Workbook for SBA 3 • 4, p. 22-4)
Anaerobic respiration does not require (1) _______________. The reactions of anaerobic
respiration occur in the (2) _______________ only.
Like aerobic respiration, it starts with (3) _______________ in which glucose is oxidized to
pyruvate. Without oxygen, pyruvate cannot proceed to the Krebs cycle and oxidative
phosphorylation. Instead, it follows different pathways and different products are formed.
Yeast is a unicellular (4) _______________. It respires anaerobically when the oxygen supply
is insufficient. In the process, pyruvate is reduced to an alcohol called (5) _______________.
(6) _______________ _______________ is released and (7) _______________ is regenerated
to pick up hydrogen in glycolysis again.
glycolysis
The breakdown of glucose into ethanol and carbon dioxide through anaerobic pathway is
called (8) _______________ _______________ (酒精發酵).
During alcoholic fermentation, glucose is partially broken down to form (9) _____________
and (10) _______________ _______________.
Compared with aerobic respiration, alcoholic fermentation of one glucose molecule produces
only (11) _______________ molecules of ATP through glycolysis. A large amount of
(12) _______________ energy is still trapped inside the ethanol formed. Therefore, much
(13) _______________ (more / less) energy is released from anaerobic respiration.
Cells of certain plants can also carry out alcoholic fermentation if oxygen is in short supply.
For example, seeds and the root cells of some plants carry out alcoholic fermentation in
(14) _______________-_______________ soil.
Skeletal muscle cells normally obtain energy through aerobic respiration. However, they also
carry out anaerobic respiration when there is a sudden increase in (15) _______________
need. This happens during strenuous exercise.
When a skeletal muscle cell respires anaerobically, glucose is first oxidized to
(16) _______________ in glycolysis. In the absence of oxygen, pyruvate accepts hydrogen
from NADH and is reduced to (17) _______________ _______________ (乳酸).
In this way, NAD is regenerated and can be used in glycolysis again. The lactic acid is released
into the (18) _______________.
2 ADP + 2 P 2 ATP
glycolysis
The breakdown of glucose into lactic acid through anaerobic pathway is called
(19) _______________ _______________ _______________ (乳酸發酵).
▲ Bicycle sprinting is
mainly an anaerobic
event
oxygen debt
time
rest exercise recovery rest
Go to
Practical 22.5 Design an investigation of alcoholic fermentation in yeast
(Book 3, p. 22-23; Practical Workbook for SBA 3 • 4, p. 22-13)
Similarities Transfer energy to the energy carrier (2) _______________, and some energy
is lost as (3) _______________
Consist of a number of reactions controlled by (4) _______________
2 Flow of energy
The exchange of molecules between photosynthesis and respiration bridges the flow of
(4) _______________ from the surroundings to organisms. This also allows the flow of
energy in (5) _______________.
oxygen
glucose
sun
energy
photosynthesis
Photosynthetic
organisms convert Through respiration,
respiration organisms break down
(6) _______________
organic food to release
energy to carbon dioxide water
the stored energy as
(7) _______________ (8) _______________.
energy stored in organic
food.
▲ How photosynthesis and respiration bridge the flow of energy from the surroundings to organisms
in photosynthesis
ATP ATP
ADP + P ADP + P
in respiration
s Respiration Photosynthesis
transformation
and heat organic food
22.1
22.2
22.3
22.5
22.6
1 organic 2 respiration 3 ATP 4 energy 5 ecosystems
6 light 7 chemical 8 ATP 9 energy 10 photosynthesis
11 Calvin 12 respiration 13 Chloroplast 14 Catabolism 15 Anabolism
16 Chemical 17 Light 18 glycolysis 19 chlorophyll 20 pyruvate
21 5-C 22 triose phosphate 23 ATP 24 oxygen 25 phosphorylation
26 NADP 27 photophosphorylation