DRUG STUDY
Name of Drug Dosage Mechanism of action Indication
Frequency
Route
1. Paracetamol 500mg, Thought to produce
(Alvedon) 1 tab q4h analgesia by blocking pain
P.O impulses by inhibiting
CLASSIFICATION: synthesis of prostaglandin in
Analgesics (Non- the CNS or of other
Opioid) & Antipyretics substances that sensitize
pain receptors to
stimulation. The drug may
relieve fever through central
action in the hypothalamic
heat-regulating center.
2. Acetylcysteine 600mg, Reduces the viscosity of
(Fluimucil) 1effervescent purulent and non purulent
tab OD, hs pulmonary secretions and
CLASSIFICATION: To be dil in ½ facilitates their removal by
Mucolytic/ cough & glass of H2O splitting disulfide bonds.
cold preparation Action increases with
increasing pH. Time to peak
effect: 5-10 min. Also
reduces liver injury due to
acetaminophen overdosage
by maintaining or restoring
glutathione levels or by
acting as an alternate
substrate for the reactive
metabolite of
acetaminophen.
3. KCL (kalium durule) 750mg Replaces potassium and
1 tab bid maintains potassium level
CLASSIFICATION: P.O Prophylaxis during
Electrolytes treatment w/ diuretics.
Contraindication Adverse reaction Nursing considerations
> Mild pain or fever > Contraindicated to Hematologic: hemolytic > Many OTC and prescription
-Headache, toothache, patients anemia, neutropenia, products contain acetaminophen;
fever associated w/ hypersensitivity to leucopenia, pancytopenia. be aware of this when
colds, menstrual pain, drugs. Hepatic: jaundice. calculating total daily dose.
muscle pain, as an Metabolic: hypoglycemia > Use liquid form for children
analgesic in rheumatic > Use cautiously in Skin: rash, urticaria. and patients who have difficulty
pain, hyperpyrexia. patients with long term swallowing.
alcohol use because > In children, don’t exceed five
therapeutic doses cause doses in 24hrs.
hepatotoxicity in these
patients
> Adjunct in the > Contraindicated to Respiratory: rhonchi, > Use plastic, glass, stainless
treatment of chronic patients bronchospasm, cough, steel, or another nonreactive
emphysema, hypersensitivity to dyspnea. metal when giving by
emphysema with drugs. CV: tachycardia, nebulization. Hand-bulb
bronchitis, chronic hypotension, hypertension, nebulizers aren’t recommended
asthmatic bronchitis, >Use cautiously in flushing, chest tightness. because output is too small and
tuberculosis, elderly or debilitated CNS: fever, drowsiness, particle size too large.
bronchiectasis, primary patients with severe abnormal thinking, giat >Drug is physically or
amyloidosis of lung, respiratory disturbances. chemically incompatible with
acute insufficiency. Use IV GI: N&V, stomatitis. tetracyclines, erythromycin
bronchopulmonary formulation cautiously Other: Rashes, drowsiness, lactobionate, amphotericin B,
disease (bronchitis, in patients with asthma rhinorrhea. and ampicillin sodium. If given
pneumonia, or a history of DRUG INTERACTION: by aerosol inhalation, nebulize
tracheobronchitis). bronchospasm. Acetylcysteine is incompatible these drugs separately.
with antibiotics and should be
administered separately.
> To prevent > Contraindicated in CNS: paresthesia of limbs, > Potassium preparations aren’t
hypokalemia patients with severe listlessness, confusion, flaccid interchangeable; verify
> Severe hypokalemia renal impairment with paralysis. preparation before use.
> Acute MI oliguria, anuria, or CV: arrhythmias, heart block, > Make sure powders are
azotemia; or with acute hypotension ECG changes. completely dissolved before
dehydration or other GI: nausea, vomiting, diarrhea giving.
conditions linked to Metabolic: hyperkalemia >Enteric-coated tablets aren’t
extensive tissue Respiratory: respiratory recommended because of
breakdown. paralysis. increased risk of GI bleeding and
small-bowel ulcerations.
- JESSE JAMES EDJEC BN2O