COMPLETE HISTOLOGY POINTS (FROM FINAL GUIDE

SERIES)
-You need to do all the Histology past-paper questions (2009-2016) and these points
only along with the diagrams from your practical copy and you are done.
-These points are extremely important to cover the 6-7 mcqs from the histology portion
that you normally skip .

- CHAPTERS FROM LAIQ HUSSAIN INCLUDED :

CHAPTER = 12,16,18,19,20,21,22,23. (MOST IMPORTANT 18,19,20,21).
Do read or memorize these important points assembled chapter wise. (ENOUGH FOR
ATTEMTPING THE PROFF UHS EXAM).

CHAPTER 12: CEREBRUM + CEREBELLUM

.Old type of cortex is known as ‘’allocortex’’
.New cortex is called ‘’neocortex’’
.In the internal pyramidal layer of primary motor area giant pyramidal cells, called Betz
cells are found.
. There are six layers of cerebral cortex :
1) Molecular layer
2) External Granular layer
3) External pyramidal layer
4) Internal Granular area
5) Internal Pyrimidal layer
6) Multiform layer
.The cerebellum consists of two hemispheres and a central vermis.
.Cerebellar cortex has three layers :
1) Molecular layer – Basket & stellate cells.
2) Purkinjee cell layer : Purkinjee cells
3) Granular layer - Granule cells.
.Afferent fibers of cerebellum include 1) climbing fibers that originate from inferior
olivary nucleus & 2) Mossy fibers that originate in spinal cord or brain stem .
. Spinal cord has a ‘H-shaped’ appearance of the grey matter with anterior , posterior &
lateral horns.
.Outer to the grey matter there is white matter of the spinal cord divided into dorsal &
ventrolateral white columns.

CHAPTER 16 : ENDOCRINE SYSTEM .

. The hypophysis or the pituitary gland is the master endocrine gland producing several
hormones .
.Hypophysis divided into (i) adenohypophysis (ii) neurohypophysis.
.Neurohypophysis derived from the neuroectoderm (diencephelon) forms posterior
pituitary .
.Adenohypophysis derived from the Rathke’s pouch (oral ectoderm) forms anterior
pituitary .
.The adenophypophysis divided into : pars distalis & pars intermedia .
. An extension of pars distalis is known as pars tuberalis .
.The neurohypophysis is divided into two parts : pars nervosa and infundibulum .
. Chromophobes and chromophils are the cells of pars distalis based upon the old
classification .
.On basis of their hormonal secretory activity there are five cell types :
1) Somatotropes (acidophilic)
2) Mammotropes (acidophilic)
3) Corticotropes (basophilic)
4) Gonadotropes ( basophilic)
5) Thryotropes (basophilic) .
.The adrenal gland is divided into outer cortex and inner medulla . The cortex further
divided into three zones :
1) zona glomerulosa
2) zona fasiculata consists of cells known as spongiocytes .
3) zona reticularis
.The adrenal medulla consists of mainly chromaffin cells on their strong ability to
chromium salts .
.The medullary cells contain a variety of soluble proteins called chromogranins.
.The parenchyma of thyroid gland consists of thyroid follicles surrounding a colloid.
. There are two types of cells in thyroid gland called : (1) follicular cells (2) parafollicular
cells.
.The follicular cells in inactive state are low cuboidal but in hyperactive state assume
columnar shape .
.Parafollicular cells also called ‘’C-cells’’ secrete hormone calcitonin which lowers the
plasma calcium level acting as an antagonist to Parathyroid hormone .
.The parathyroid gland consists of (1) chief cells (2) oxyphill cells .
.Pineal gland consists of (1) pinealocytes (2) interstitial cells .
.Pinealocytes secrete melatonin.
. Calcified concretions appear in pineal ECM, these mulberry shaped structures are titled
as ‘’CORPORA ARENACEA’’.

CHAPTER 18 (DIGESTIVE SYSTEM) V.IMP

- TONGUE
.The epithelium is of stratified squamous type, being non-keratinized on the ventral
(lower surface) and partially keratinized on the dorsal (upper) surface of the tongue .
.The dorsal surface of tongue divided into anterior 2/3rd & posterior 1/3rd by a V-
shaped sulcus terminalis .
.There are lingual papillae on the dorsal surface of tongue & of four types :
(a) Filiform
(b) Fungiform
(c) Circumvallate
(d) Foliate
.Filform papillae are the most numerous of lingual papillae .
.Fungiform papillae are the most abundant at the tip of the tongue .
.Numerous taste buds are present on circumvallate papillae .
.There are Von Ebner’s glands , anterior lingual glands & mucous glands present in the
tongue .
.Foliate papillae are less in number and present on the sides of the tongue .
.Tubular digestive tract wall has the following four concentric layers or coats :
(a) Mucosa
(b) Submucosa
(c) Muscularis externa
(d) Serosa
-ESOPHAGUS :
.Mucosa further divided into :
1) Epithelium : Stratified squamous non-keratinized epithelium .
2) Lamina Propria : CT and lymphatic nodules.
3) Muscularis mucosa :Smooth muscles running mainly in longitudinal direction.
- Submucosa : Has esophageal glands proper.
-Muscularis externa (V.IMP) : esophagus consists of inner circular & outer longitudinal
layers but differ in the way that it has both skeletal and smooth muscles in following
arrangement .
UPPER 1/3RD : ONLY SKELETAL
MIDDLE 1/3RD : MIXTURE OF SMOOTH & SKELETAL
LOWER 1/3RD : ONLY SMOOTH .
-Abdominal part of esophagus is serosa , whereas thoracic & cervical part is adventitia.
STOMACH : (IMP)
.Mucosa of empty stomach thrown into longitudinal folds called ‘rugae’
.No glands present in the submucosa of the stomach .
.Mucularis externa composed of three layers of smooth muscle :
(1) inner oblique
(2) middle circular (thickened at pylorus to form the pyloric sphincter)
(3) outer longitudinal .
Lamina propria consists of three types of glands :
-Fundic glands
-Cardiac glands
-Pyloric glands .
.Cells of the fundic gland :
(1) Mucous neck cells
(2) Parietal cells (most imp)
(3) Chief cells a.k.a (zymogenic cells or peptic cells) secretes pepsinogen.
(4) Endocrine cells
(5) Stem cells.
Parietal cells :
.Secrete HCL & intrinsic factor and are also called oxyntic cells .
.Large round to pyramidal cells.
.Centrally located nucleus, large Golgi apparatus , eosinophilic stain .
.EM study reveals presence of intracellular canaliculus .
.There are microtubules and vesicles .
SMALL INTESTINE :
-Several features that increase the surface area for absorption includes :
(1) Plicae Circularis (a.k.a) Valves of Kerckering .
.Most pronounced in jejunum and absent in the proximal part of duodenum and distal
half of ileum .
(2) Villi
.Ten-fold increase in surface area .
.Difference in the shape of villi in different parts of small intestine : mixture of leaf-
shaped & finger like villi in duodenum . Ileum entirely has finger shaped villi .
(3) Microvilli
. Enterocytes have microvilli on their apical surfaces .
.Increase surface area by a factor of 20 (MOST) .
(4) Crypts of leiberkuhn

-The mucosa of the small intestine is lined by simple columnar epithelium .

-This epithelium consists of 5 types of cells :
(1) Enterocytes
(2) Goblet cells
(3) Enteroendocrine cells
(4) Paneth cells
(5) M cells.
Features of cells
ENTEROCYTES :
-Tall columnar cells , oval nucleus .
-apical surface has thousands of microvilli.
-Hence a striated brush border .
-EM reveals a glycocalyx coat on tip of microvilli.
-Bind to each other by junctional complexes .
GOBLET CELLS :
-Mucus secreting , unicellular .
-few microvilli.
ENTEROENDOCRINE CELLS : (remember just the name) .
PANETH CELLS :
-exculsively in the bottom of crypts of Leiberkuhn .
-Secretory product has the ability to kill certain bacteria and protozoa , hence regulate
intestinal flora .
M-cells :
-These are antigen-transporting cells .
-Play a very important role in the immunological surveillance of the intestinal luminal
regions .
-The submucosa of the small intestine there are glands called Brunners gland of the
duodenum .
-The muscularis externa consists of inner circular & outer longitudinal layers of smooth
muscles in between which they consist of Myenteric plexus .
-Only the posterior surface of duodenum has adventitia , the rest of small intestine has
serosa .
COLON :
-The muscularis externa of colon consists of inner circular & outer longitudinal layer of
smooth muscle .
-The outer longitudinal are gathered into three, flat bands called teniae coli .
-The serosa of colon is characterized by presence of numerous small protuberances
called appendices epiploicae composed of adipose tissue .
APPENDIX :
-The lamina propria of the appendix is heavily infiltrated with lymphocytes and contains
numerous lymphoid nodules .
-Teniae coli are absent .
RECTUM & ANAL CANAL : (IMP)
-Rectum is mostly like the colon .
-The anal canal mucosa shows a number of longitudinal folds called anal columns .
-The depressions between anal columns are called anal sinuses .
-The lower ends of the columns are joined to one another by mucosal folds known as
anal valves .
- Above the level of anal valves , mucosa is lined by simple columnar epithelium .
- Below the level of anal valves, mucosa is lined by stratified squamous non keratinized
type .
-There are anal glands in the submucosa .
-The muscularis externa consists of inner circular & outer longitudinal layers of smooth
muscle .
-At level of anal columns the inner circular layer becomes thickened to form the internal
anal sphincter .
-The external anal sphincter consists of skeletal muscle belongs to pelvic floor
musculature .
SALIVARY GLANDS :
-The salivary glands are compounds having a highly branched duct system .
-Ducts classified into generally three types : (1) intercalated (2) striated (3) excretory .
INTERCALATED DUCTS : SIMPLE CUBOID EPITHELIUM
STRIATED DUCTS :LOW COLUMNAR EPITHELIUM .
INTRALOBULAR DUCTS = INTERCALATED + STRIATED DUCTS .
EXCRETORY DUCTS = INTERLOBULAR + INTRALOBULAR + MAIN DUCTS .
-The main duct is lined by stratified columnar epithelium that changes to stratified
squamous non keratinized near its opening to oral cavity .
PAROTID = SEROUS IN NATURE .
SUBMANDIBULAR = MIXED .
SUBLINGUAL = MUCOUS IN NATURE .
PANCREAS :
-Major part of the organ is made up of exocrine portion .
-The endocrine consists of islets of Langherans .
-There are serous cells in the pancreatic acini , apical region contains acidophilic
zymogen granules .
-Some secretions of the pancreatic acini also exhibit low cuboidal epithelial cells known
as ‘’centro-acinar cells’’
-A cells secrete – glucagon .
-B cells secrete – insulin .
-D cells secrete- somatostatin .
LIVER : (VERY IMPORTANT)
-The liver is covered by a thin connective tissue capsule called ‘’Glisson’s capsule’’.
- FIG 18-15 OF LAIQ HUSSAIN HISTOLOGY IS A MUST!!
-The parenchyma consists of epithelial cells called hepatocytes arranged as anastomotic
plates .
-Between the plates are present blood sinosoids called hepatic sinusoids .
-Three types of lobules in liver structure :
(a) Classic Hepatic Lobule .
(b) Portal Lobule .
( c ) Hepatic acinus .
-There’s a relatively large venule called ‘central vein ‘ in the classic lobule .
-At the angles of the hexagonal hepatic lobules are present roughly triangle areas called
portal areas .
-Bile flows in narrow channels called Bile canaliculi .
Features of hepatocytes : (imp)
1) polygonal cells with six or more surfaces .
2) packed closely , arranged as anastomotic plates arranged radially around the central
vein .
3) most have single spherical nucleus .
4) Have the usual cell organelles e.g Golgi , mitochondria.
5) Presence of intracellular channels called bile canaliculi .
6) The surface of the hepatocyte is separated from the wall of the sinusoid by a narrow
space that contains type III collaged called the ‘’perisinusoidal space’’ or space of DISSE .
-The perisinusoidal space consists of star shaped cells called hepatic stellate cells (or Ito
cells) .
-Hepatic sinusoids have two types of cells :
.(1) ENDOTHELIAL CELLS
(2) KUPFFER CELLS .
CHAPTER -19 (URINARY SYSTEM)**
- The human kidney has two main regions called – ‘’medulla’’ & ‘’cortex.’’
- The uriniferous tubule has two parts – ‘’a nephron’’ & ‘’a collecting tubule.’’
- There are three types of nephrons –(1) ‘’superficial’’ cortical (2) midcortical or
intermediate cortical , (3) juxtamedullary nephrons.
- Differences among these three nephrons include. (1) having their renal corpuscles in
outer part of renal cortex & consist short loop of Henle.
- (2) having their corpuscles in midregion of cortex and loop of Henle of intermediate
length.
- (3) having their corpuscles in deepest part of cortex and long loop of Henle’s.
- Renal corpuscle has a Bowmann’s capsul & glomerulus.
- The podocytes are large , irregularly star-shaped cells which share a common basal
lamina with the endothelial cells of the glomerular capillaries .
- Numerous secondary processes, known as PEDICELS make direct contact with the
capsular surface of the common basal lamina .
- The Foot processes (pedicels) of each podocytes interdigitate with those of the
neighbouring podocytes. The elongated spaces between the interdigitating pedicels are
called ‘’filtration slits.’’
- The filtration barrier constituted by structures that intervene between the blood in the
glomerular capillaries & the filtrate in the capsular space .
- Barrier consists of 3 components :
.The fenestrated capillary endothelium .
.The glomerular basement membrane .
. The filtration slits with slits diaphragms .
-The PCT (proximal convulated tubule) is the tortuous and the longest part of nephron .
-Examination of a cross section of the proximal convulated tubule under LM reveals that
this part of the nephron is lined by a simple cuboidal epithelium .
-Each lining cell contains a centrally located spherical nucleus, luminal surface of cells
shows a ‘’brush-border.’’
-The neighbouring cells of PCT are bound to each other by junctional complexes
consisting of tight junctions & zonulae adherentes.
- Principal function of PCT is to actively absorb sodium from the glomerular filtrate & to
pump it into the intercellular space .
-The Loop of Henle consists of four parts : (i) a thick descending segment . (ii) a thin
descending segment (iii) thin ascending segment (iv) thick ascending segment .
-The distal tubule of the nephron comprises of two parts – pars recta (distal straight
tubule) & pars convulata (distal convulated tubule) .
-Distal straight tubule lined by cuboidal cells .
-Distal convulated tubule have no brush border unlike PCT and have very small microvilli
unlike PCT aswell .
-In other differences from PCT, the Distal Convulated tubule has is smaller in diameter &
begins at the vascular pole .
-Principal function of DCT is the resorption of sodium from the glomerular filtrate .
-Collecting tubules & collecting ducts :
. Collecting tubules have an average diameter of 40 micrometers and have simple
cuboidal epithelium .
.Collecting ducts are lined by simple columnar epithelium .
. Collecting ducts contain two types of cells called the light cells & the dark cells .
.The light cells are also called the principal cells pale staining , oval , centrally placed
nuclei .
.The dark cells are also called intercalated cells , are fewer and contain central round
nuclei .
-JG APPARATUS :
.comprises of three components (i) Macula Densa (ii) JG cells (iii) Extraglomerular
mesangial cells .
Features of Macula Densa cells :
. Simple cuboidal epithelium.
. Cells are tall columnar in shape , Golgi apparatus is located in subnuclear position .
Darker , denser appearance .
JG CELLS Features :
. Large size and their nuclei are spherical. Cytoplasm full of granules , which do not stain
. secrete rennin .
-Extraglomerular mesangial cells are also called lacis cells .
URETER :
.THREE COATS (i) Mucosa (ii) Muscularis (iii) Adventitia .
.Mucosa . into folds, star shaped lumen . transitional epithelium with 3-5 cell layers
.lamina propria has CT .
.Muscularis thick with two layers of smooth muscle not clearly demarcated . Inner
longitudinal , outer circular layer whereas a third layer of longitudinally running muscle
fibers is added outer to the circular layer .
.The adventita outermost layer , with loose CT , blood vessls , lymphatics .
URINARY BLADDER :
MUCOSA numerous folds that disappear when bladder is distended with urine .
Epithelium Transitional epithelium , layers change with state of distention . In empty
transitional epithelium shows 6-8 layers whereas in distended it shows 2-3 layers .
PLAQUES region present on the epithelium of the urinary bladder .
MUSCULARIS Consists of interlacing bundles of smooth muscle fibers and distinction
into layers is not possible except in the neck region of the bladder .
In this region , thin inner longitudinal , thick middle circular, thin outer longitudinal .
Adventitia/Serosa Most covered by adventita , superior surface covered by serosa .
URETHRA :
FEMALE URETHRA Initial part of urethra lined by transitional epithelium whereas
remaining part lined by stratified squamous non keratinized epithelium . Numerous
mucous secreting simple acinar glands called urethral glands or glands of Littre.
MALE URETHRA Prostatic urethra = Transitional epithelium .
Membranous urethra = Stratified columnar epithelium interspersed with patches of
pseudostratified columnar epithelium .
Penile Urethra = Psuedostratified epithelium except at its distal part where it is lined by
stratified squamous non keratinized epithelium .
CHAPTER – 20 ( MALE REPRODUCTIVE SYSTEM) .
- Each testes is covered by a thick capsule of dense irregular CT called tunica albuginea .
- Thin and incomplete CT septa called septula testis radiate from the mediastinum testis
to the capsule and divide further the interior of organ to 250 pyrimadal
intercommunicating compartments called testicular lobules .
- Beneath tunica albuginea a layer called tunica vasculosa lining septula testis .
- Each testicular lobes contains one to four highly convulated seminferous tubules .
- Seminferous tubules are 0.2 mm in diameter .
- Tubuli recti constitute the initial part of the male genital duct system .
- The tubuli recti pass into mediastinum testis to join a network of anastomosing
channels called rete testis .
- SEMINIFEROUS TUBULES ARE LINED BY A COMPLEX SEMINIFEROUS EPITHELIUM
WHICH IS MODIFIED STRATIFIED CUBOIDAL EPITHELIUM .
- Spermatogonia are the cells of seminiferous epithelium and are divided into TYPE A
DARK & TYPE A PALE spermatogonia along with TYPE B spermatogonia depending on
the nuclear structure .
- Sertoli cells also called the sustenacular cells , tall columnar cells extend from basal
lamina to the lumen of seminiferous tubules .
- Sertoli cell has nucleus that exhibits distinctive features like (foldings in nuclear
envelope ) or ( nucleolus being prominent) .
- Has lipid droplets, glycogen granules, spindle shaped crystalloid . ER , GOLGI,
mitochondria under EM .
- Cells of lateral wall bound by occluding junctiond .
- Basal compartment has spermatogonia and primary spermatocytes .
- Adluminal compartment has secondary spermatocytes, spermatids , spermatozoa.
- FUNCTIONS ** physical and nutritional support to developing germ cells , important
blood-testis barrier formation , phagocytosis , secretion of AMH (antimullerian
hormone) , antigen binding protein production , secretion of inhibin .
- Occluding junctions between the adjacent sertoli cells establish a blood-testis barrier
between the basal and adluminal compartments of seminiferous tubules .
- Role in isolating the haploid germ cells in a compartment to prevent any kind of
immune response against the cells .
- Interstitial cells of leydig arranged as groups in close association to blood capillaries
have following features large ovoid cells , central dark staining nucleus , eosinophilic
cytoplasm rich in lipid droplets . Rod shaped crystalloids of Reinke are commonly seen in
the cytoplasm of interstitial cells . They secrete the male sex hormone testosterone .
-Tubuli recti or vasa recta proximal part lined by sertoli cells whereas distal part lined by
simple cuboidal epithelium .
- Rete testis have simple cuboidal epithelium .
- Ductuli efferentes has columnar epithelium .
-EPIDIDYMIS :
.Coma shaped body that overlies the posterior superior surface of tests
.Cross section reveals that the duct of epididymis is lined by a pseudostratified columnar
epithelium .
Functions include the storage of spermatozoa, its transport to the ductus deferens ,
reabsorption of most of the fluid leaving testes .
-DUCTUS DEFERENS (VAS DEFERENS) .
.Three coats (Mucosa, Muscularis , Adventita ) .
-Mucosa lumen star shaped , pseudostratified columnar epithelium in which tall
columnar cells bear stereocilia .
-Muscularis Composed of three layers of smooth muscle thin inner longitudinal,
thick middle circular , thick outer longitudinal .
- Adventita
-The distal end of the ductus deferens is dilated to form the ampulla .
SEMINAL VESICLES :
Mucosa thrown into longitudinal folds. Lining epithelium of pseudostratified columnar
variety .
Principal cells tall columnar and bear short microvilli on apical surface . Short basal cells
rest on basal lamina .
-Muscularis Consists of inner circular & outer longitudinal layers of smooth muscle .
- Seminal vesicles functions as glands which secrete a yellow viscous fluid that
constitutes about 70 % of the volume of semen .
- The secretion also contains the yellowish pigment called ‘’FLAVIN’’.
PROSTRATE GLAND (IMP) .
.Largest accessory sex gland of male .
. Covered by a thin capsule of dense irregular CT.
. Stroma of the prostrate is fibromuscular consisting of collagen , elastic & smooth
muscle fibers.
.Parenchyma has 30-50 tubuloacinar glands .
-Mucosal glands , submucosal glands & main prostratic glands .
- Small spherical bodies known as prostratic concentrations or CORPORA AMYLACEA are
observed in the lumina of some of the prostatic alveoli .
- The parenchyma of the gland is divided into three zones :
- (i) peripheral zone = contains the main prostatic glands about 70% of glandular mass .
major site of prostatic cancer.
- (ii) transitional zone = contains the submucosal glands , site of BPH ( BENIGN
PROSTATIC HYPERPLASIA) .
- Central Zone = mucosal glands , resistant to hyperplasia as well as malignancy .

CHAPTER 21 ( FEMALE REPRODUCTIVE SYSTEM)

- The surface of ovary is covered by a simple cuboidal epithelium ( also called germinal
epithelium) .
- Ovary consists of two zones (central deep zone of medulla & outer zone of cortex) .
-The ovarian cortex has scattered spherical bodies called ovarian follicles .
- A layer of dense CT , known as tunica albuginea lies between germinal epithelium &
underlying cortex .
- The ovaries of a female child contain only one type of ovarian follicles called primordial
follicles .
- Ovary of an adult female has three varieties of ovarian follicles .
- Primordial follicle under the influence of gonadotropic hormones secreted by
adenohyophyisis is called the growing follicles .
- Only one growing follicles mature while others undergo atresia .
- Remains of the ovulated follicle are converted into temperory glandular structure
called corpus luteum .
- Primordial follicle has an immature ovum arrested in prophase of meiosis I .
- The oocyte of primordial follicle contains a large , eccentric situarted, vesicular nucleus
with prominent nucleolus .
- The follicular cells also called granulose cells are squamous epithelial cells that
surround the oocyte and attached to each other by desmosomes.
- Primordial follicle grows into Unilaminar primary follicle Multilaminar primary
follicle Secondar follicle Mature Graafian follicle .
- At Unilaminar primary follicle stage , a layer of amorphous , homogeneous material
appears between the oocyte and the granulose cells called ‘’zona pellucida.’’
- Layers of theca interna & theca externa are formed during the Multilaminar follicle
stage .
- The inner layer theca interna consists mainly of cuboidal secretory cells . Synthesize
and secrete the androgen androstenedione, which passes to the granulose cells where it
is converted into estrogen called estradiol .
- Theca externa outer layer of theca folliculi consist of fibroblasts,collagen fibers &
smooth muscle fibers.
- Secondary follicle stage is characterized by the presence of a cavity called the antrum
folliculi .
- The liquor folliculi is an exudate of plasma that appear in the clefts between the
stratum granalosum .
- Most secondary follicles undergo atresia , one of them matures and becomes a
Graafian follicle or a tertiary follicle .
- Ruptured follicle does not disintegrate but once is transformed into a temperory
endocrine organ called corpus luteum .
- The granulose lutein cells are pale staining , large cells, cytoplasm yellowish with the
lutein pigment , principal function to secrete progesterone .
- The theca lutein cells have fat droplets in cytoplasm , mitochondria with tubular
cristae, SER. Secretes estrogens as well as progesterones .
- Degeneration of the corpus luteum results in autolysis of the lutein cells and increase
in CT, finally the whole mass is transformed into a whitish scar called corpus albicans .
UTERINE TUBES .
-Mucosa longitudinal folds throughout the length , epithelium lining the oviducts is of
simple columnar variety and contains either ciliated or non ciliated cells . Lamina propria
of uterine tubes has loose CT, reticular & collagen fibers .
-Muscularis thick inner circular & a thin outer longitudinal layer of smooth muscle
fibers .
-Outermost covering of the uterine tube is called ‘’serosa.’’
UTERUS .
-OUTER LAYER = PERIMETRIUM
-MIDDLE LAYER = MYOMETRIUM
-INNER LAYER = ENDOMETRIUM .
-Perimetrium is either serosa or adventitia depending on the surface of uterus being
examined .
-Myometrium is the thickest coat with three layers of smooth muscles. (i) thin outer
layer of longitudinally arranged muscles. (ii) middle layer of circularly disposed muscle
fibers. (iii) inner layer of longitudinal muscles .
- Endometrium = lining epithelium is of simple columnar variety with two types of cells
(i) ciliated (ii) secretory .
-The functionalis also called the stratum functonale is the thick superficial zone which is
sloughed off at the beginning of each menstrual cycle .
-The basalis or stratum basale is the deeper, narrower zone of the endometrium .
-4 phases of menstrual cycle (i) proliferative (ii) secretory (iii) premenstrual (iv)
menstrual .
VAGINA :
-THREE COATS ( MUCOSA, MUSCULARIS, ADVENTITIA) .
-MUCOSA transverse folds or rugae, two layers = epithelium & lamina propria.
Epithelium of the stratified squamous non keratinized variety although some of the
superficial cells of the epithelium contains keratohyalin granules.
Lamina propria with layer of loose CT, containing a number of elastic fibers .
Muscularis Consists of smooth muscle fibers which are arranged into two
intermingling layers , the inner layer is composed mainly of the circularly arranged
muscle fibers. The thick outer layer is composed of bundles of longitudinally running
smooth muscle fibers .
Adventita layer of dense CT that binds the vagina to the surrounding structures .
-The vaginal wall has no glands.

CHAPTER 22 (EAR)
- Auricle is composed of ‘’ELASTIC CARTILAGE.’’
- The cartilaginous part of meatus contains ‘’ceruminous glands.’’
- Secretory product of sebaceous & ceruminous glands mix to form the ear wax.
- Auditory tube is lined by pseudo-stratified columnar ciliated epithelium.
- Membranous labyrinth is filled with fluid called ‘’endolymph.’’
- Osseous labyrinth consist of central cavity called ‘’vestibule.’’
- Cristae ampullaris are 3 in number whereas macula are two in number.
- Stereocilia of Hair cells are embedded in a thick glycoprotein material called ‘’cupula.’’
- Otoliths are composed of calcium carbonate.
- Tectorial membrane overlies the organ of corti.

CHAPTER-23 (EYE)
-Middle layer of eyeball is also called ‘’uveal region.’’
- Corneoscleral junction is called corneal limbus .
-Corneal epithelium = Stratified squamous non-keratinized.
-Bowmann’s membrane of cornea contains type-1 collagen fibers.
-Retina develops as invagination of forebrain called the ‘’optic vesicle.’’
-Dilated fibers radiating from the ciliary processes are called ‘’zonular fibers.’’
-Contraction of longitudinal fibers of ciliary muscles Facilitates the drainage of
Aqueous Humor.
- Contraction of radial fibers of ciliary muscle cause the lens to flatten for the distant
vision .
- Retinal pigment epithelium is a single layer of low columnar cells.
- Lens capsule contain collagen type IV.