See discussions, stats, and author profiles for this publication at: https://www.researchgate.

net/publication/248398594

Skeletal Muscle Physiology

Article  in  The Scientific World Journal · June 2013

DOI: 10.1155/2013/782352 · Source: PubMed

CITATIONS READS

3 1,153

4 authors:

Lucas Guimarães-Ferreira Humberto Nicastro

Universidade Federal do Espírito Santo Body 4 Life Institute
56 PUBLICATIONS   544 CITATIONS    49 PUBLICATIONS   544 CITATIONS   

SEE PROFILE SEE PROFILE

Jacob M Wilson Nelo Eidy Zanchi

Applied Science and Performance Institute Universidade Federal do Maranhão
158 PUBLICATIONS   3,567 CITATIONS    72 PUBLICATIONS   1,240 CITATIONS   

SEE PROFILE SEE PROFILE

Some of the authors of this publication are also working on these related projects:

Hmb position stand View project

EFEITO DO TREINAMENTO RESISTIDO SOBRE A CINÉTICA DE CÁLCIO INTRACELULAR MIOCÁRDICA DE RATOS OBESOS View project

All content following this page was uploaded by Lucas Guimarães-Ferreira on 28 May 2014.

The user has requested enhancement of the downloaded file.

Hindawi Publishing Corporation
The Scientific World Journal
Volume 2013, Article ID 782352, 2 pages
http://dx.doi.org/10.1155/2013/782352

Editorial
Skeletal Muscle Physiology

Lucas Guimarães-Ferreira,1 Humberto Nicastro,2 Jacob Wilson,3

and Nelo Eidy Zanchi4
1
Exercise Metabolism Research Group, Center of Physical Education and Sports, Federal University of Espirito Santo,
29075810 Vitória, ES, Brazil
2
Laboratory of Applied Nutrition and Metabolism, School of Sports and Physical Education, University of São Paulo,
05508-030 São Paulo, SP, Brazil
3
Human Performance and Sports Nutrition Laboratory, The University of Tampa, Tampa, FL 33606, USA
4
Department of Physiology and Biophysics, University of São Paulo, 05508-900 São Paulo, SP, Brazil

Correspondence should be addressed to Nelo Eidy Zanchi; neloz@ig.com.br

Received 18 April 2013; Accepted 18 April 2013

Copyright © 2013 Lucas Guimarães-Ferreira et al. This is an open access article distributed under the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is
properly cited.

In the beginning of the last century, muscle proteins
were viewed as static structural molecules not capable of
being utilized by other tissues or organs. This concept
was accepted until the 30s, where Rudolf Schoenheimer
presented strong evidences about the “Dynamic State of
Body Constituents,” which means that skeletal muscle is
not only capable of contracting but also capable of releas-
ing nitrogen derived molecules to be utilized by other
organs and tissues (Guggenheim, 1991) [1]. Such concept
established that skeletal muscle is a highly plastic tissue,
adapting its structure and metabolism in response to diverse
conditions such as contractile activity, mechanical overload,
and nutrients. From this point of view several questions
arise, specifically, how form follows function of skeletal
muscles, as well as the synergistic role of nutrients. A
large number of research groups around the world are
helping to clarify this and many other questions. In par-
ticular in the last four decades, the growth in the number
of publications on skeletal muscle subject is noteworthy
(Figure 1).
In this special issue, the reader will be brought directly
to a wide spectrum of articles regarding the skeletal muscle
tissue. From France, a new hypothesis concerning how to
consume amino acids and deal with catabolic conditions also
is put in debate, focusing on the anabolic threshold concept
(D. Dardevet et al., 2012). From the University of Tokyo,
Japan, A. Wagatsuma and K. Sakuma (2013) summarize
the current knowledge about the role of mitochondria as
a regulator of myogenesis. From Brazil, C. O. Assumpção
et al. (2013) present an extensive review on the effects of
exercise-induced muscle damage on running economy in
humans. Also, W. S. Dantas et al. (2013) discuss the impact
of polycystic ovary syndrome on skeletal muscle tissue. A.
Carsana (2013), from Italy, reviewed the documented cases
of exertional rhabdomyolysis or stress-induced malignant
hyperthermia and reported a possible association with RYR1
gene polymorphism. This special issue also presents original
articles focusing on the cytokine response of skeletal muscle
cells according its differentiation stage (M. Podbregar et al.,
2013), the effects of tissue culture conditions on in vitro
myogenesis (S. Hinds et al., 2013) and the differences in
spontaneous physical activity between mice substrains (D.
Coletti et al., 2013). All these discussions are being provided in
order to generate new benefits and from athletes to debilitated
populations; from basic to applied sciences. In this issue, our
focus was not to restrict but, on the contrary, to be capable
of proposing new hypotheses and ideas based on the current
knowledge.
2 The Scientific World Journal

1500

1250
Number of publications

1000

750

500

250

0
1972
1973
1974
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
Year

Figure 1: Number of publications in Medline database with “skeletal muscle” present on title. Data from the US National Library of Medicine
National Institutes of Health (http://www.ncbi.nlm.nih.gov/pubmed?term=skeletal%20muscle [Title]).

Acknowledgment
We are pretty sure that our objective was successfully
achieved. The reader will be surprised with the quality of the
manuscripts as well as the diversity of skeletal muscle physiol-
ogy research around the globe.
Lucas Guimarães-Ferreira
Humberto Nicastro
Jacob Wilson
Nelo Eidy Zanchi

References
[1] K. Y. Guggenheim, “Rudolf Schoenheimer and the concept of
the dynamic state of body constituents,” Journal of Nutrition,
vol. 121, no. 11, pp. 1701–1704, 1991.
 Journal of
Complex Analysis Algebra Journal of
Applied Mathematics
 Advances in

Decision
Abstract and
Applied Analysis
Sciences

Hindawi Publishing Corporation
Hindawi Publishing Corporation Hindawi Publishing Corporation Hindawi Publishing Corporation http://www.hindawi.com Volume 2013 Hindawi Publishing Corporation
http://www.hindawi.com Volume 2013 http://www.hindawi.com Volume 2013 http://www.hindawi.com Volume 2013 http://www.hindawi.com Volume 2013

Journal of
Complex Journal of
Systems Mathematics
Hindawi Publishing Corporation Hindawi Publishing Corporation
http://www.hindawi.com Volume 2013 http://www.hindawi.com Volume 2013

Submit your manuscripts at

http://www.hindawi.com

Mathematical Problems Journal of

in Engineering Industrial Mathematics
Hindawi Publishing Corporation Hindawi Publishing Corporation
http://www.hindawi.com Volume 2013 http://www.hindawi.com Volume 2013

International Journal of

Journal of Journal of
Optimization
Mathematics and
Mathematical
Discrete Mathematics
Sciences

Hindawi Publishing Corporation

http://www.hindawi.com
Volume 2013
Game Theory
Hindawi Publishing Corporation
http://www.hindawi.com
Volume 2013
Hindawi Publishing Corporation
http://www.hindawi.com
Volume 2013
Geometry
Hindawi Publishing Corporation
http://www.hindawi.com Volume 2013
Hindawi Publishing Corporation
http://www.hindawi.com Volume 2013

ISRN ISRN ISRN ISRN

Applied Mathematical ISRN Operations Computational
Mathematics Physics Combinatorics Research Mathematics
Hindawi Publishing Corporation Hindawi Publishing Corporation Hindawi Publishing Corporation Hindawi Publishing Corporation Hindawi Publishing Corporation
http://www.hindawi.com Volume 2013 http://www.hindawi.com Volume 2013 http://www.hindawi.com Volume 2013 http://www.hindawi.com Volume 2013 http://www.hindawi.com Volume 2013

View publication stats