CHAPTER 5: CELLULAR RESPIRATION

1. The overall reaction for the aerobic respiration of glucose is summarized as ......
A. C6H12O6 + 6 O2 + 6 H2O → 6 CO2 + 12 H2O + Energy
B. C6H12O6 + 12 H2O + 6 CO2 → 6 O2 + ATP + Energy
C. C4H12O4 + 6 O2 + 6 H2O → 6 CO2 + ATP + Energy
D. C4H12O2 + 6 O2 + ATP → 6 CO2 + 12 H2O + Energy

2. Which of the following is NOT TRUE of the Krebs cycle?

A. Three molecules of NADH are produced per molecule of glucose
B. Two molecules of FADH2 are produced per molecule of glucose
C. Addition of Acetyl CoA to oxaloacetic acid starts the cycle
D. GTP is produced and converted to ATP

3. Which of the following processes makes direct use of oxygen?

A. Glycolysis
B. Fermentation
C. Krebs cycle
D. Electron transport chain

4. How many carbon dioxide are released as the result of the oxidation of one
molecule of pyruvate?
A. 3
B. 4
C. 6
D. 8

5. What is the name of the process that generate ATP molecule using the flow of
hydrogen ions?
A. Substrate-level phosphorylation
B. Fermentation
C. Reduction
D. Chemiosmosis

6. Which are possible products of fermentation?

A. Lactic acid
B. Alcohol
C. CO2
D. All of these are possible

7. Which of these is NOT TRUE of the electron transport system?

A. Located in the inner membrane of mitochondria
B. Produces more NADH than any metabolic pathway
C. Contains cytochrome molecules
D. Ends when oxygen accepts electrons

8. Which of the following does NOT occur during the Krebs cycle reactions within
the matrix of the mitochondrion?
A. CO2 production
B. NADH production
C. ATP production

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D. Acetyl CoA production

9. What happens to most of the NADH molecules in cell metabolism?

A. They act as oxidizing agent in glycolysis
B. Oxidized in inner membrane of mitochondria in ETC
C. Oxidized in the Calvin cycle
D. Combine with malate as part of the Krebs cycle

10. A small amount of ATP is made in glycolysis by which of the following

processes?
A. Transfer of a phosphate group from a fragment of glucose to ADP by
substrate-level phosphorylation
B. Phosphorylation of glucose
C. Phosphorylation of fructose 6-phosphate
D. Attachment of a free inorganic phosphate (Pi) group to ADP to make ATP

11. How many molecules of oxygen gas (O2) are used during the glycolysis of one
glucose molecule?
A. 0
B. 1
C. 16
D. 38

12. Which of the following sequences CORRECTLY describes the synthesis of ATP
associated with electron transport in mitochondria?
A. NADH, electron transport, proton gradient, chemiosmosis
B. NADH, electron transport, chemiosmosis, proton gradient
C. NADH, electron transport, proton gradient, substrate-level phosphorylation
D. NADH, electron transport, substrate-level phosphorylation, ATP

13. Which of the following substances, if any, is NOT directly involved in oxidative
phosphorylation?
A. Glucose
B. Proton
C. ADP
D. Oxygen

14. Which of the following best describes the electron transport chain?
A. Electrons are pumped across a membrane by active transport
B. Electrons are passed from one carrier to another, releasing a little energy at
each step
C. Acetyl CoA is fully oxidized to CO2
D. Hydrogen atoms are added to CO2 to make an energy-rich compound

15. What are the products of alcohol fermentation?

A. ATP, CO2 and lactate
B. ATP, NADH and pyruvate
C. ATP, CO2 and ethanol
D. ATP, pyruvate and Acetyl CoA

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16. Which statement best describe about decarboxylation?

A. Occurs as part of the Krebs cycle
B. Involves the removal of a carboxyl group from a substrate
C. Occurs during aerobic respiration and produces CO 2
D. All of the above

17. Which of the following statement is TRUE during Krebs cycle?

A. Acetyl CoA combines with malate to form citrate
B. Isocitrate is reduced to form α-ketoglutarate
C. Succinate is oxidized to fumarate
D. Malate is reduced to form oxaloacetate and NAD + is reduced to NADH

18. What ions are accumulated in the intermembrane space of the mitochondria
during the electron transport chain process?
A. Hydrogen
B. Phosphorus
C. Potassium
D. Sodium

19. Which of the followings happened in fermentation?

A. Oxygen is needed as a final electron acceptor
B. More ATP are produced
C. NADH is used to reduce pyruvate to lactate
D. ATP is used to convert pyruvate to ethanol and CO2

20. Sports physiologists at an Olympic training center wanted to monitor athletes to

determine at what point their muscles were functioning anaerobically. They
could do this by checking for a buildup of which of the following compounds?
A. ATP
B. Lactate
C. Carbon dioxide
D. ADP

21. Which of the following reactions produce ATP during glycolysis?

A Phosphoenolpyruvate pyruvate
B Glucose glucose-6-phosphate
C Fructose 6-phosphate fructose 1,6-bisphosphate
D Glyceraldehyde 3-phosphate 1,3-bisphosphoglycerate

22. Which of the following occur in cytosol of a cell during the catabolism of
glucose?
A. Chemiosmosis
B. Electron transport chain
C. Krebs cycle
D. Glycolysis

23. At which stages of aerobic respiration is ATP produced by substrate-level

phosphorylation?

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A Glycolysis and Krebs cycle

B Glycolysis and oxidative phosphorylation
C Glycolysis and link reaction
D Link reaction and oxidative phosphorylation

24. Which of the following explains why the pH in the intermembrane space is lower
than that of the mitochondrial matrix?
A Large amount of ATP is produced in the matrix.
B Lactic acid accumulates in the intermembrane space during anaerobic
respiration.
C There is a high concentration of pyruvate in the matrix.
D There is a high concentration of protons in the intermembrane space due to
chemiosmosis.

25. Which of the following substances are produced in the link reaction?
I ATP
II Acetyl CoA
III Carbon dioxide
IV FADH2

A I and II only
B I and III only
C II, and III only
D I, II, III and IV

26. How many molecules of carbon dioxide are produced for each molecules of
glucose that undergoes aerobic cellular respiration?
A 2
B 3
C 4
D 6

27. Which of the following is NOT the difference between aerobic and anaerobic
respiration?
I Aerobic respiration involve glycolysis and oxidative phosphorylation whlie
anaerobic respiration only involve glycolysis.
II Aerobic respiration occurs in cytosol and mitochondria while anaerobic
respiration occurs only in cytosol.
III Aerobic respiration produced 38 ATP while anaerobic respiration produced
2 ATP
IV In aerobic respiration, NADH and FADH2 enter electron transport chain
while in anaerobic respiration, only NADH will enter electron transport
chain.

A I and II only
B I and III only
C I and IV only
D I, II and III only

28 Which is the most CORRECT definition of Substrate Level Phosphorylation?

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A Formation of ADP by which an enzyme transfer a phosphate from an

intermediate substrate to ATP.
B Formation of ATP by which an enzyme transfer a phosphate from an
intermediate substrate to ADP.
C Formation of ATP by using energy derived from the redox reactions of
Elecron Transport Chain.
D Formation of ADP by using energy derived from the redox reactions of
Chemiosmosis.

29. Which of the following is an electron carrier?

A ATP synthase
B ATP
C Ubiquinone
D Coenzyme A

30. In lactic acid fermentation,

A Oxygen is needed as a final electron acceptor
B ATP is used to convert pyruvate to ethanol and CO2
C NADH is used to reduce pyruvate to lactate
D NADH is used to reduce pyruvate to acetaldehyde

31. What process in your cell that produce the CO2 that you exhale?
A Glycolysis and Krebs Cycle.
B Substrate-Level Phosphorylaion and Oxidative Phosphorylation.
C Glycolysis and Link Reaction.
D Oxidative Decarboxylation of Pyruvate and Citric Acid Cycle.

32. Which of the following are TRUE about phosphorylation?

I Phosphorylation is a process that produce ATP
II In Substrate level phosphorylation, a phosphate group is transferred
directly from a substrate to an ADP molecule
III Oxidative phosphorylation occurs in the inner membrane of
mitochondria which involve ETC only.
A I only
B I and II only
C II and III only
D I, II and III

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