Clinical practice guidelines (CPGs) are evidence-based documents which encourage the
implementation of current evidence to day-to-day emergency nursing practices. CPGs provide
guidelines focused on a comprehensive evaluation and literature relevant study on a therapeutic topic. Helps nurses determine effective best practices and improve patient care. Also helps nursing respond to changes in the healthcare environment, patient populations and government regulations. Research evidence and clinical practice are important for the secure, open, reliable and productive delivery of healthcare and for meeting patient, family and social standards. Nurses are inquisitive, think deeply about the quality of their patients, and want to learn their patients' alternative treatments—all of which render them ideally appropriate for study. Research provides the foundation for high-quality, evidence-based nursing care. Guideline development has 4 stages. First, guidelines will be focused on the latest existing scientific data and a systematic literature review is then carried out to find findings from empirical trials on the appropriateness and efficacy of various therapeutic approaches. “Evidence-based care” comes from researchers. The inconsistent application of the research evidence into action reflects health science and clinical experience. Since, the first studies in this review were conducted and the increasing emphasis in the past 15 years on evidence-based practice. Despite the extensive advocacy of evidence-based clinical practice, the emergence of new translational study positions for nurses in major medical centers and payment programs for Medicare throughout the United States related to particular evidence-based activities, studies continue to suggest much room for improvement. Then, using the study data, recommendations are created, typically by some sort of small group work, with participation from as many stakeholders as possible. Despite the methodological problems present in the majority of experiments, nurses utilize study in their work. There is a strong need to implement consistent data use metrics and detailed well-designed studies investigating the usage of testing by nurses and their effect on patient results. Next, the Guideline is assessed by asking for transparency, internal accuracy and acceptability from experts not involved in the Guideline creation. The rule will then be checked to see whether it is practical for usage in daily practice in specified health care settings. As such, work undertaken by nurses is widely regarded as a vital avenue for realistic and efficient approaches to enhance patient care. However, well-established obstacles remain to undertaking and turning results of work into action. Finally, the guideline will be revised over a given period of time, and updated to take new information into account.