Endo Final

Endo2007_KCC COVER 2/16/07 3:04 PM Page 1
THE ENDOCRINE SOCIETY’S 89th Annual Meeting
ENDO O7
June 2 – 5
FINAL REGISTRATION & PROGRAM INFORMATION

Endo2007_KCC COVER 2/19/07 3:38 PM Page 2
REGISTER EARLY
AND SAVE 20% ON
ENDO 07 REGISTRATION.
ENDO 07 is designed to deliver the networking of smaller meeting formats while
covering the breadth and scope that only the world's largest gathering of endocrinologists
can provide. The 2007 scientific program, presented by over 350 speakers, includes
16 plenary lectures, 77 symposia, 180 Meet-the-Professor sessions and greater networking
and professional development opportunities than ever before. All of this in Toronto,
one of the most diverse, modern and accessible cities in the
world. Don’t miss out on this huge opportunity to save.
REGISTER NOW.
To register now or for more information about ENDO 07,

visit www.endo-society.org/endo. The early registration offer ends April 7th.
Endo2007_KCC TEXT 2/16/07 1:53 PM Page 3
AN OPPORTUNITY THIS GOOD

Only Comes Around Once A Year.
E N D O 07 , June 2–5, 2 007
Meet the Chairs of the TABLE OF CONTENTS

Annual Meeting Steering Committee
“From my earliest days as an ENDO attendee, the Scientific Program

meeting has always impressed me with the melding
Program-at-a-Glance 4
of basic science, clinical science, and clinical
practice. The opportunities for networking and Highlights 6
collaborating with some of the best endocrinologists Pre-Conference Workshops & Events 10
in the world are what make ENDO so unique.”
Basic Science Sessions 12
Clinical Science & Practice Sessions 17
William F Young, Jr, MSc, MD Oral & Poster Sessions 24
Chair
Continuing Medical Education 25
“From a research perspective, ENDO is all- Professional Development Opportunities 26

encompassing. Only at ENDO can you find the most
exciting advances in your individual field as well as
expand your perspective into other areas that could Conference Events 28
potentially impact your own research. Nowhere else
can you find more ground-breaking research.” Registration, Hotel, Travel Information 30
Toronto Guide & Tours 36

Andrea C Gore, PhD
Basic Science Chair
Attendee Resources 38
“As clinical endocrinologists, we need to be Annual Meeting Contributors 41

knowledgeable about a wide array of conditions
and their respective treatment options beyond our Contact Information 43
specialization. I believe The Endocrine Society’s
Annual Meeting is the ideal place to find all the
latest information you need to better your Registration Forms 45
practice.”
Peter J Trainer, MD, FRCP

Clinical Science & Practice Chair
3
Endo2007_KCC TEXT 2/19/07 10:05 AM Page 4
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HIGHLIGHTS
Plenary Lectures 5:3 0 – 6:3 0 P M
Scientific Program
Does Breast Cancer Start in the Womb?

Saturday, June 2 Ana M Soto, MD, Tufts Univ Sch of Med
8:00 – 9:15 A M Recent data have suggested that perturbations
Presidential Plenary Session in the fetal environment may predispose
(Supported by Novo Nordisk Inc.) individuals to disease and/or organ dysfunction,
Clinical Investigator Award Lecture which become apparent in adulthood. This
Human Obesity & Insulin Resistance: Lessons from new emphasis on the fetal origins of adult
Extreme Phenotypes diseases has prompted scientists to hypothesize
Stephen O’Rahilly, MD, Univ of Cambridge/Addenbrooke’s Hosp that fetal exposure to environmental estrogens
may be an underlying cause of the increased
We have developed unique cohorts of patients incidence of uterine leiomyoma, testicular cancer, and breast cancer
with either severe early-onset obesity or observed in European and US populations over the last 50 years.
extreme insulin resistance. I will describe how Humans are routinely exposed to bisphenol-A (BPA), an estrogenic
we have used these cohorts to discover novel compound that leaches from dental materials, food and beverage
monogenic and oligogenic disorders of energy containers, and other plastic consumer products. Does prenatal
balance and/or insulin sensitivity. These exposure to BPA induce mammary gland neoplasia? I will discuss
discoveries have shed light on important our work with a rat model where fetal exposure to BPA induces
control points for human energy balance and the development of ductal hyperplasias and carcinoma in situ that
insulin sensitivity and have identified some genetic defects manifest during early adulthood. Exposure to xenoestrogens during
sufficiently common to have implications for clinical diagnostic early development may be an underlying cause of the increased
approaches to obesity. Finally, we have identified one genetic incidence of breast cancer observed over the last 50 years.
defect of energy balance, which can be dramatically corrected
by mechanism-based therapy. Nuclear Receptors on Chromatin:
Multiple Enzymes at Work
Presidential Plenary Session Trevor Archer, PhD, NIEHS/NIH
Variations in Cortisol Sensitivity: The Clinical Implications
of Polymorphisms in the Glucocorticoid Receptor Gene The temporal and spatial extraction of
Steven W Lamberts, MD, PhD, Erasmus Med Ctr (Netherlands) information from the genome is critical for
normal growth and development. Higher
In normal individuals, there is a marked organisms encapsulate this genetic and epigenetic
variability in the sensitivity to cortisol. This information into a specialized structure called
is clinically evident in the variable occurrence chromatin. We will show that steroid hormone-
of adverse effects during treatment with activated transcription, highlighting recent
glucocorticoids. This variability in cortisol studies with the glucocorticoid receptor, requires
sensitivity is in part related to functional changes in this chromatin architecture. For this task, steroid
polymorphisms in the glucocorticoid receptor receptors require two distinct classes of chromatin-modifying
gene. In population studies, these polymorphisms enzymes, one that disrupts chromatin structure using ATP-dependent
are associated with variations in body composition, insulin chromatin remodeling, and another whose actions regulate the
sensitivity, and longevity. We will discuss whether knowledge covalent modification of histone proteins.
concerning these polymorphisms in an individual patient can help
to predict “a safe dose” of glucocorticoids in pharmacotherapy.
CUSTOMIZE YOUR ENDO 07 EXPERIENCE.

Look for these symbols throughout the program.
These symbols signify the core content of each session.
B C T E
Basic Clinical Translational Ethics
HIGHLIGHTS
Sunday, June 3 New Perspectives in Endometriosis
Scientific Program
8:00 – 9:15 A M Linda C Giudice, MD, PhD, Univ of California-San Francisco
Advances in the Understanding of the Genetic Basis of Endometriosis is a common gynecologic disorder
Bone & Mineral Disorders associated with pelvic pain, infertility, and
Rajesh V Thakker, MD, Univ of Oxford (UK) increased risk of ovarian cancer. Diagnosis may
be delayed by years, and medical and surgical
Disorders of bone and calcium homeostasis,
therapies are less than satisfactory in most
which include osteoporosis and kidney stones,
women. Recent advances demonstrate that there
are common. The parathyroid glands play a
is a genetic component to endometriosis and
central role in these homeostatic pathways and
that endometriosis lesions make estrogen and
dysfunction of these glands, which may lead to
are resistant to progesterone, complicating the therapeutic paradigm,
hyper- or hypo-calcemia, is often associated
but also providing opportunities for innovation. This plenary
with genetic abnormalities. Investigation of
lecture will focus on current approaches to diagnosis and treatment
these genetic abnormalities has identified novel
of this disorder and how recent advances in molecular medicine
receptors, channels, and signaling pathways. Translation of these
are leading to novel diagnostics and therapeutics.
advances to the clinical setting has facilitated the diagnosis and
treatments of bone and mineral disorders. These advances and the
manner in which they have increased our understanding of the Monday, June 4
underlying molecular mechanisms will be reviewed. 8:00 – 9:15 A M
Regulation of Beta-Cell Mass in Humans: A Potential
Roy O Greep Award Lecture Therapeutic Target in Type 1 & 2 Diabetes?
Pituitary Development & Disease: Roles of Transcription Peter C Butler, MD, Univ of California-Los Angeles
Factors & Signaling Pathways Both type 1 and 2 diabetes are characterized by
Sally A Camper, PhD, Univ of Michigan deficits in beta-cell mass. The likely underlying
Pituitary hormone deficiency and pituitary mechanisms leading to these deficits will be
adenomas are common problems. Studies in discussed, including potential increased beta-cell
genetically engineered and mutant mice have loss and/or decreased beta-cell formation.
advanced understanding of the mechanisms Replacement of beta-cell mass by pancreas
underlying these disease processes. In most transplantation has been shown to reverse
cases, genes discovered in the mouse have metabolic defects in both type 1 and 2 diabetes.
quickly led to the discovery of lesions in human Organ donor pancreases are limited in supply, and this strategy
patients and have revealed the genetic requires long-term immunosuppression. What are the opportunities
hierarchy of control of pituitary cell specification and growth. for beta-cell regeneration in humans with type 1 and 2 diabetes?
What obstacles must be overcome to meet these objectives? These
questions will be addressed with the state-of-the-art information
5:3 0 – 6:3 0 P M at the time of presentation.
Tissue-Engineered Follicles
Teresa K Woodruff, PhD, Northwestern Univ
Edwin B Astwood Award Lecture
Few options currently exist for young women Lipid Metabolism & Diabetes Research
who face a life-preserving but fertility-threatening Lawrence C Chan, DSc, MBBS, Baylor Coll of Med
chemo- or radiation therapy for cancer.
Emergency in vitro fertilization may be an option I will discuss areas of lipid metabolism and
for those who can delay cancer-directed treatment diabetes research that have produced new concepts
and have a partner or sperm bank material for and paradigms that are applicable to broad areas
the generation of embryos. Ovarian tissue of cell biology and medicine. The first area deals
cryopreservation and autotransplantation is an with the elucidation of the structure and
option to restore fertility; however, it may increase the risk of metabolism of apoB and the soluble
reintroduction of hematologic or disseminated neoplastic cells. apolipoproteins, which led to new concepts
Methods to grow immature follicles in vitro eliminate the potential and pathways years ago, but whose relevance is
reintroduction of nascent cancer cells, provide autonomous genetic increasingly applicable, not only to lipid metabolism, but also to
material for women wishing to begin their own family, and eliminate other biomedical disciplines. Next, I will review how lipid droplet
the need to cryopreserve embryos. New 3-D culture systems simulate proteins regulate lipid homeostasis and the role of bone
physiological conditions using alginate hydrogels to mimic the marrow-derived cells in chronic diabetic complications. Finally, I
ovarian environment. I will provide an update on the progress in will discuss recent research on diabetes gene therapy, which may
understanding ovarian follicle growth and oocyte maturation lead to a new treatment, but which also changes our thinking on how
in vitro and the birth of healthy fertile mice from follicle cultures. transcription factors regulate gene expression and cell differentiation.
Page content as of January 20, 2007 – for up-to-date information, visit

www.endo-society.org/endo/program/index.cfm?view=highlights
B C T E
7
HIGHLIGHTS
Plenary Lectures Continued Maternal Programming of Neuroendocrine Systems
Scientific Program
through DNA Methylation

5:3 0 – 6:3 0 P M Michael Meaney, PhD, McGill Univ (Canada)
Molecular & Cellular Controls on the Development of
This presentation will focus on the importance
Type 1 Diabetes of alterations in the methylation of specific
Diane J Mathis, PhD, Joslin Diab Ctr/Harvard Med Sch DNA sites as a mechanism for the effects of
The development of type 1 diabetes has multiple variations in postnatal maternal care on the
checkpoints, encompassing emergence of the hypothalamic pituitary adrenal and gonadal
autoreactive T-cell repertoire, initiation of axes, with a focus on the promoter regions of
insulitis, and conversion of insulitis to diabetes. the glucocorticoid receptor and estrogen receptor
The focus of this presentation will be molecules alpha genes in specific brain regions. The
and cells that control these different checkpoints working hypothesis is that environmental
and genetic influences on them. events can alter DNA methylation marks even in post-mitotic
cells and may therefore program stable individual differences in
reproductive and
Predicting Endocrine Autoimmunity defensive ‘strategies’ that are predictive of health outcomes over
the lifespan.
Anthony Weetman, MD, Univ of Sheffield (UK)
Autoimmune endocrine diseases frequently 5:3 0 – 6:3 0 P M
coexist in patients and are also associated with
other non-endocrine autoimmune conditions. Social Regulation of the Brain: Status, Sex & Size
Recent developments, especially in genetic Russell D Fernald, PhD, Stanford Univ
analysis, which have shed light on these Social species respond to social context by
associations and illuminated the pathogenesis modifying their behavior. Animals also
of these common disorders, will be outlined.
modulate physiological systems, adjusting
Whilst genetic predictors for the development
expression of ligands and receptors to keep
of autoimmune endocrinopathies in unaffected
their physiological state synchronized with their
individuals remain elusive, serological and clinical parameters can
social state. I will present data to show that
be applied to target those most at risk.
social encounters can change the brain,
particularly as it regulates the reproductive axis.
Tuesday, June 5 In response to social cues, genes, receptors, and neural circuits
8:00 – 9:15 A M change, and with this rewiring comes altered function.
Gerald D Aurbach Award Lecture
Sleep Loss as a Risk Factor for Obesity & Diabetes Nanotechnology in the Characterization, Prevention &
Eve Van Cauter, PhD, Univ of Chicago Treatment of Disease
James R Baker, Jr, MD, Univ of Michigan
During the past few decades, sleep curtailment
has become a very common behavior in The relevance of nanotechnology as it pertains
industrialized countries. The aging of the to biology and medicine will be reviewed. The
population is associated with an increased relationship of nanoscale dimensions and tools
prevalence of sleep disturbances. These trends for understanding biological structures and the
for shorter sleep duration and poorer sleep quality application of this understanding to therapeutic
have developed over the same time period as development will be examined. Specific
the dramatic increase in the prevalence of obesity examples of nanoscale materials that have
and diabetes. There is rapidly accumulating unique functional activities in biological
evidence from laboratory and epidemiologic studies to indicate that systems due to their size will be presented.
chronic partial sleep loss and decreased sleep quality could increase
the risk of obesity and diabetes. Laboratory studies in healthy young
volunteers have shown that experimental sleep restriction is
associated with an adverse impact on glucose homeostasis and with
a dysregulation of the neuroendocrine control of appetite, with
decreased leptin and increased ghrelin levels, consistent with a risk
of overeating and weight gain. Insulin sensitivity decreases rapidly
and markedly when either sleep duration or sleep quality is reduced
experimentally without adequate compensation in beta-cell
function, resulting in an elevated risk of diabetes. Prospective
epidemiologic studies in both children and adults are consistent
with a causative role of sleep disturbances in the increased risk
of obesity and diabetes.

8 B C T E
HIGHLIGHTS
Out-of-the-Box Workshops Clark T Sawin Memorial Lecture new
Scientific Program
The Out-of-the-Box Workshops invite (Supported by Novo Nordisk Inc.)
participants to step outside of their In the First Annual Clark T Sawin Memorial History of
professional roles and examine how the Endocrinology Lecture, Professor Bliss, author of the first biography
field of endocrinology touches the larger of Harvey Cushing to appear in five decades, will discuss some
world around us. These presentations unique perspectives on Harvey Cushing and the formative years
are designed to highlight issues of of endocrinology and The Endocrine Society. Following his
critical importance at the intersection presentation, Professor Bliss will be available for book signings of
of science, medicine, and public policy. his biographies on Cushing and Osler and his new edition of
“The Discovery of Insulin.”
Saturday, June 2
12:15 – 1:00 P M Sunday, June 3
Public Policy & Obesity E 12:3 0 – 1:15 P M
Michelle Mello, Harvard Sch of Public Hlth Harvey Cushing & the Early Years of “Endo-Criminology”
Michael Bliss, Univ of Toronto
There has been a lot of effort, particularly at the state government
level, to try to use public policy to prevent obesity, with a lot of
those efforts focusing on children and youth in the public schools.
What is the appropriate role for the government in influencing Clinical Practice Guideline Sessions new
an individual’s personal decisions about activity level and At the Clinical Practice Guideline Sessions, you will receive an
consumption? My position tends to be that there is a role for in-depth look at three of the Society’s guidelines. The Guideline
government in trying to lead people to healthier lifestyles, but Chairs will review the highlights, key recommendations, and
there is a significant backlash toward such moves. challenges, followed by a moderated 30-minute open discussion
with the Guideline Chair and Guideline Task Force members.
Sunday, June 3
12:15 – 1:00 P M Sunday, June 3
Endocrinology & Industry – Selling Sickness? E
8:3 0 – 9:15 A M
Pediatric Obesity
Alan Cassels, Univ of Victoria (Canada)
Moderator: Michael Freemark, Duke Univ Med Ctr
I think menopause stands as an example of a very successful Panel: Gil August (Chair), Ilene Fennoy, Francine R Kaufman,
medicalization of a normal passage of life. If you are female and Robert H Lustig, Janet H Silverstein, Phyllis W Speiser,
you live long enough, you will go through menopause, and if you Dennis M Styne
can produce products that treat this condition, you can be
guaranteed a large market. That whole term “hormone replacement” Monday, June 4
has really been developed and created largely by the 8:3 0 – 9:15 A M
manufacturers of estrogen replacement.
Thyroid Disease in Pregnancy
Moderator: Wilmar Wiersinga, Univ of Amsterdam
Monday, June 4 Panel: Les DeGroot (Chair), Marcos S Abalovich, Nobuyuki Amino,
12:15 – 1:00 P M Linda A Barbour, Rhoda H Cobin, Daniel Glinoer, Susan J Mandel,
The NIH Clinical & Translational Science Awards: Creating Alex Stagnaro-Green
Synergies between Basic & Clinical Investigators
Barbara Alving, Natl Ctr for Res Resources/NIH Tuesday, June 5
It is time to work together, time to be more than just the 8:3 0-9:15 A M
isolated researcher doing one-off clinical trials. It’s time to find Androgen Therapy in Women
out how we can synergize all of the tools and all of the intellect Moderator: Glenn D Braunstein, Cedars-Sinai Med Ctr/Univ of
that we have and make sure that we utilize all the discoveries that California-Los Angeles Sch of Med
have been made. Panel: Margaret E Wierman (Chair), Rosemary Basson, Susan R
Davis, Sundeep Khosla, Karen K Miller, William Rosner, Nanette
Santoro

B C T E
9
PRE-CONFERENCE WORKSHOPS & EVENTS ( Friday, June 1 )

Thyroid Sonography Hands-On Workshop 4:4 5 – 5:3 0 P M
Scientific Program
11:3 0 A M – 7:00 P M Closing the Loop

Stuart Weinzimer, Yale Univ
This interactive hands-on workshop is taught by leading
thyroidologists using ultrasound for thyroid disorders. Presenters 5:3 0 – 6:00 P M
will teach the use of ultrasound in the diagnostic and therapeutic Closing Remarks & Refreshments
evaluation of thyroid nodules, as well as in patients with thyroid
cancer and hyperparathyroidism. Attendees will have an opportunity
to utilize ultrasound equipment and learn the procedures of American Board of Internal Medicine new
diagnostic thyroid ultrasound and ultrasound-guided fine-needle Self-Evaluation Process (ABIM SEP)
aspiration. Registration fees: Endocrine Society Members $350;
nonmembers $400; fellows/students $250. Limited to 65 registrants.
5:00 – 9:00 P M
In conjunction with ENDO 07, The Endocrine Society will con-
duct an interactive Recertification Prep Course designed around
Using Continuous Glucose Monitors to the ABIM SEP Endocrinology, Diabetes and Metabolism
Endocrinology Recent Advances Module 23-R. This comprehensive
Improve Diabetes Care: A Review of the session focuses on preparation for the ABIM recertification exam
Latest Research & Clinical Practice and also serves as an excellent update and overview for review
Strategies new purposes.
1:3 0 – 6:00 P M Three expert faculties will lead you through an in-depth coverage
(Cosponsored by The Endocrine Society & The Juvenile Diabetes of content areas with 60 case-based questions using an audience
Research Foundation; Supported by Abbott Diabetes Care & response system (ARS). Submit your answer sheets (located in
the purchased module) to ABIM to obtain CME credits for the
Medtronic Minimed, Inc.) Maintenance of Certification (MOC) Program.
Learn the latest information on continuous glucose monitoring,
including an overview of the technology, research on its effective- Learning Objectives:
ness in both pediatric and adult patients with type 1 and type 2 • Learn and receive feedback on new diagnostic testing options
diabetes, and guidance on its clinical application. Eligible for • Learn and receive feedback on new therapeutic options
4.0 AMA PRA Category 1 CreditsTM. The registration form will be
• Receive feedback on clinical decisions regarding diagnosis and
available in March.
treatment of patient problems
1:3 0 – 1:4 0 P M • Learn the similarities and differences in diagnostic and treatment
Introduction options for common and unusual problems in the discipline
Aaron Kowalski, Juvenile Diabetes Res Fdn & Jennifer Larsen, Target audience: Clinical Practitioners, Clinical Researchers,
Univ of Nebraska and Diplomates of the ABIM who hold time-limited (current or
lapsed) or non-time limited certificates in internal medicine
1:4 0 – 2:2 0 P M and/or subspecialties and added qualifications of internal medicine
Overview of Continuous Glucose Monitoring (CGM) are eligible to apply.
Steve Edelman, Univ of California-San Diego
Advance purchase of the module is encouraged; bring your module
2:2 0 – 2:5 0 P M to the session. The answer sheet needed for MOC is located in
Accuracy of CGM the purchased module. Diplomates may seek MOC only in
William Clarke, Univ of Virginia disciplines in which they have been certified. The session fee is
separate from registration fees. For advance purchase of the
2:5 0 – 4:00 P M module, or for additional information about the MOC program,
Clinical Use of Continuous Glucose Monitoring visit www.abim.org or call 800.441.2246, extension 3593.
Irl Hirsch, Univ of Washington
Satish Garg, Barbara Davis, Univ of Colorado
Francine Kaufman, Univ of Southern California
William Tamborlane, Yale Univ
4:00 – 4:15 P M
Break
4:15 – 4:4 5 P M
Incorporating CGM in a Health Care Practice
Dan Mendelson, Avalere Hlth

www.endo-society.org/endo/events/preconference.cfm
10 B C T E
PRE-CONFERENCE WORKSHOPS & EVENTS ( Friday, June 1 )

Fellows & Students Day Workshop
Scientific Program
new Basic Fellows & Students Track
8:00 A M – 6:00 P M 9:3 0 A M – 6:00 P M
(Supported by Abbott Laboratories, AstraZeneca, Berlex Laboratories, The Rewards of a Career in Science Transcription & Novel
Novo Nordisk Inc., Pfizer, Inc. & Sanofi-Aventis) Mechanisms of Gene Regulation
This workshop provides valuable trainee education in both basic Transcription in Live Cells
and clinical tracks. The Basic Track will include leading
researchers presenting exciting new technologies, personal Dispelling the Myths: Research experiences in Academia,
experiences, tips on choosing a postdoc, job opportunities, and Industry, & Government
much more. The Clinical Track will include thought leaders Break-Out Sessions:
presenting perspectives on the diagnosis and treatment of Basic Science Outside the US: Is the Grass Greener?
endocrine disorders, advice on setting up a private practice, and Networking Mentoring & Self-promotion Basics for
strategies for achieving a healthy balance between career and Basic Scientists
personal life. Selected applicants will receive travel reimbursement, Finding the Right Flavor of Job for You
one night of housing, and complimentary registration to ENDO 07.
For application details, visit www.endo-society.org/endo/development. Finding the Right Postdoc
Careers in Industry
8:00 – 8:2 0 A M Career/Life Balance Panel Discussion
Welcome & Overview
Leonard Wartofsky, President, The Endocrine Society
Fellow & Student Reception
8:2 0 – 8:3 0 A M 6:3 0 – 7:3 0 P M
Finding Your Niche at ENDO All fellows and students attending ENDO 07 are invited to this
The ENDO 07 Program Chairs popular event. Catch up with colleagues and friends, enjoy light
refreshments, and join The Endocrine Society in honoring all
8:3 0 – 9:3 0 A M ENDO travel grant recipients. Please indicate your interest in
Plenary Lectures attending this reception by marking the appropriate box on the
ENDO 07 Registration Form (see page 45).
Clinical Fellows Track Contact: Danielle Jordan at djordan@endo-society.org
9:3 0 A M – 6:00 P M or 301.951.2616.
Insights into Thyroid Cancer
Thyroid Disorders & Pregnancy
Bone & Mineral Update
Break-Out Sessions:
Male Reproduction
PCOS
Pituitary Disorders
Diabetes & Lipids
Osteoporosis
Obesity Management
Endocrine Hypertension
Update in Diabetes Management
Pediatric Endocrinology
Obesity Pathophysiology: Adipose Tissue as an Endocrine Organ
Pituitary
Private Practice
Career/Life Balance Panel Discussion

www.endo-society.org/endo/events/preconference.cfm
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11
BASIC SCIENCE SESSIONS

Scientific Program
Symposia New Insights into Phosphate

Regulation in Health & Disease T
Novel Genes in Thyroid Cancer T
Chair: Ronald Koenig, Univ of Michigan
Chair: Suzanne Jan De Beur, Johns Hopkins Med Ctr
Saturday, June 2 Univ Sch of Med MCIP-1 & Thyroid Cancer Metastases
9:3 0 – 11:00 A M Regulation of Phosphate Metabolism: Matthew Ringel, Ohio State Univ
Central & Peripheral Actions of Normal Physiology & Pathophysiology of Role of microRNAs in Follicular Thyroid
Ghrelin T Disease Carcinogenesis
Chair: Ezio Ghigo, Univ of Turin/Osped Sherri-Ann Burnett, Massachusetts Charis Eng, Cleveland Clin
Molinette (Italy) Gen Hosp PTTG Promotes Thyroid Cancer
Central & Peripheral Effects of Ghrelin: Role of FGF23 & Other Phosphatonins in Progression
Interaction with AMPK Disorders of Phosphate Metabolism Christopher McCabe, Univ of Birmingham
Marta Korbonits, St Bartholomew’s Hosp (UK) Anthony Portale, Univ of California-San
Regulation of GH Secretion Francisco Prolactin Action in Normal &
Michael Thorner, Univ of Virginia Hlth Syst Neoplastic Tissue B
Insights into the Regulation of Phosphate
Gastrokinetic Effects Chair: Nelson D Horseman, Univ of
Metabolism Using Transgenic &
Theo Peeters, Katholieke Univ Leuven Cincinnati Coll of Med
Knockout Mice
(Belgium) Regulation of Mammary Cell Proliferation
Rajiv Kumar, Mayo Clin
Linda A Schuler, Univ of Wisconsin
CRH: 25 Years Later T Sex Steroids & Energy Balance B Prolactin in Mammary Carcinoma
Chair: Wylie Vale, Salk Inst Chair: Sharon Wardlaw, Columbia Univ Christopher J Ormandy, Garvan Inst of Med
CRH in Early-Life Stress & H-P-A Axis Coll of Phys & Surg Res (Australia)
Neuroplasticity Estrogen & Energy Balance In Vivo Vasoinhibins: A Family of N-terminal
Tallie Baram, Univ of California-Irvine Deborah Clegg, Univ of Cincinnati Prolactin Fragments that Inhibits
Physiological Functions of Urocortin 2 Neural Basis for Sex Differences in Angiogenesis & Vascular Function
Alon Chen, Weizmann Inst of Sci (Israel) Feeding Behavior Carmen Clapp, Univ Natl Autonoma de
Urocortins in Cardiovascular Health & Toshiya Funabashi, Yokohama City Univ Sch Mexico
Disease of Med (Japan)
A Mark Richards, Univ of Otago (New Estrogen & Energy-Relevant Regulation of Metabolism by the
Zealand) Neuropeptide Expression Brainstem B
Denise Belsham, Univ of Toronto/Univ Hlth Chair: Karen Briski, Univ of Louisiana Sch
Endocrine Lessons from Evolution B Network of Pharm
Chair: Michel Sanders, Univ of Minnesota Sites of Action of Circulating Ghrelin
Med Sch 3:4 5 – 5:15 P M Yukari Date, Miyazaki Med Coll (Japan)
Olfactory Control of Reproduction Mediators of PTH Action B Peripheral Signals onto Brainstem &
Catherine Dulac, Harvard Univ Chair: Sundeep Khosla, Mayo Clinic POMC Neurons
Roles of Leptin in Cold-Blooded Animals PTH & Wnt Interaction Suzanne Appleyard, Oregon Hlth & Sci
Robert Denver, Univ of Michigan Matthew Gillespie, St Vincent’s Inst of Med Univ
Sexual Differentiation of the Female Res (Australia) Hindbrain Glucose Sensing Controls
Spotted Hyena: Reproductive Costs of Growth Factors as Mediators of PTH Multiple Glucoregulatory Responses
Natural Androgenization In Utero Action in Bone Sue Ritter, Washington State Univ
Stephen Glickman, Univ of California- Hiroshi Kawaguchi, Univ of Tokyo
Berkeley PTH Modulation of the Bone Marrow Regulation of Puberty T
Microenvironment: Bone Stem Cells Chair: Selma Feldman Witchel, Children’s
Genomic Actions of Nuclear Laura M Calvi, Univ of Rochester Hosp of Pittsburgh
Receptors B The Impact of Endocrine-Disrupting
Chair: Steven K Nordeen, Univ of Colorado Mouse Models of Nuclear Receptor- Chemicals on Female Puberty
Hlth Sci Ctr Related Diseases T Jean Bourguignon, Univ of Liege (Belgium)
Nuclear Recepor Activity & Chromatin Chair: Kathleen Ann Mahon, Baylor Coll Evolution of Puberty
Jiemin Wong, Baylor Coll of Med of Med Mark Hanson, Univ of
Genomic Analysis of Estrogen Action Oncogenic AR Mutation Southampton/Princess Anne Hosp (UK)
Henk Stunnenberg, Nijmegen Ctr for Molec Wayne Tilley, Univ of Adelaide/Hanson Inst Role of GPR54 Mutations in Pubertal
Life Sci (Netherlands) Xenobiotic Receptors & Immune Disorders
Nuclear Receptor & Cofactor Dynamics Dysfunction Ana Latronico, Hosp das Clinicas da Fac de
in the Nucleus Bruce Blumberg, Univ of California-Irvine Medicina da USP (Brazil)
Michael Mancini, Baylor Coll of Med Kennedy Disease: Mouse Models, Molecular
Mechanisms & Therapeutic Strategies
Andrew Lieberman, Univ of Michigan
Med Sch

www.endo-society.org/endo/program/index.cfm?view=basic
12 B C T E

Signaling Processes of the Embryonic Oxytocin, Estradiol & Neuroplasticity in Phosphorylation of Estrogen Receptors
Scientific Program
& Adult Pituitary B Lactation Didier Picard, Univ of Geneva
Chair: Sally Camper, Univ of Michigan Dionysia Theodosis, Univ de Bordeaux Acetylation of Nuclear Receptors
Med Sch (France) Richard Pestell, Kimmel Cancer Ctr
Developmental Signals during Pituitary Estrogen & Hippocampal Neural (Philadelphia, PA)
Organogenesis Plasticity
Jacques Drouin, Inst de Recherches Clin de Catherine Woolley, Northwestern Univ 3:4 5 – 5:15 P M
Montreal
Adiponectin, Obestatin & Ghrelin
The Pituitary Side Population: An Hormone Disruption & Early Origins Signaling Surprises B
Embryonic Compartment in the Adult of Disease B Chair: Gary Sweeney, York Univ (Canada)
Gland? Chair: Christine L Clarke, Westmead Inst Obestatin
Hugo Vankelecom, Katholieke Univ Leuven for Cancer Res (Australia) Aaron Hsueh, Stanford Univ Sch of Med
(Belgium) Fibroids & Early Development Adiponectin
Molecular Targets in Pituitary Tumors Cheryl Walker, Univ of Texas MD Anderson Lily Dong, Univ of Texas Hlth Sci Ctr-San
Anthony Heaney, Cedars-Sinai Med Ctr Cancer Ctr Antonio
Developmental Origin of PCOS: Is Ghrelin Receptor Mutations
Sunday, June 3 Maternal Hyperandrogenism the Culprit? Birgitte Holst, Univ of Copenhagen
9:3 0 – 11:00 A M Vasantha Padmanabhan, Univ of Michigan
Structural Determinants of Ligand- Growth Hormone in Aging T
Control of GnRH: The Role of Genetic
Studies in Expanding Our Dependent Specificity in the Chair: Barbara C Hansen, Univ of South
Understanding of Neuroendocrine Mineralocorticoid Receptor Florida-Tampa
Mechanisms T Paul M Foster, NIEHS/NIH Maintenance of Cognitive Function in
Chair: Kathleen Whitlock, Cornell Univ the Aging Brain by GH
Insulin, Calories & Longevity B
Lessons from GPR54 Mutations in William Sonntag, Wake Forest Univ Sch of
Chair: Joan Lakoski, Univ of Pittsburgh Sch
Idiopathic Hypogonadotropic Med
of Hlth Sci
Hypogonadism GH-Regulated Genes as Markers of Aging
Insulin/IGF Regulation of Drosophila Aging
Nicolas de Roux, Hosp Robert Debra (France) John Kopchick, Ohio Univ/Edison Biotech
Marc Tatar, Brown Univ
Novel Genes Causing Kallmann’s Inst
lnsulin, Caloric Restriction & Lifespan in
Syndrome GH & Lifespan in Mammals
Mice
Nelly Pitteloud, Massachusetts Gen Hosp Holly Brown-Borg, Univ of North Dakota
Kevin Flurkey, Jackson Lab
Analysis of Kallmann’s Syndrome through
Sirtuins & Beta Cells
the Prism of Structural Biology Life Cycle of the GnRH Neuron B
Shin Imai, Washington Univ Sch of Med
Moosa Mohammadi, New York Univ (Supported by Abbott Diagnostics)
Med Ctr Isoform-Specific Functions of T3 Chair: Ei Terasawa, Univ of Wisconsin
Receptors B Fetal Development of GnRH Neuronal
Growth Hormone Signaling B Chair: Ann Marie Zavacki, Brigham & Systems
(Supported by Novo Nordisk Inc.) Women’s Hosp Stuart Tobet, Colorado State Univ
Chair: Ilene Fennoy, Columbia Univ Role of TR Isoforms in Signaling Pathway Kisspeptin, GnRH & Puberty
Med Ctr during Intestine Development Robert Steiner, Univ of Washington
Complexity of GH Actions at the Jacques Samarut, Ecole Normale Superieure Neuroendocrine Regulation in Menopause
Growth Plate de Lyons (France) Naomi Rance, Univ of Arizona
Jeffrey Baron, NICHD/NIH Thyroid Hormone Receptor- (TR- )Plays
GH, Neuronal Stem Cells & SOCS-2 a Critical Role in Skeletal Development Normal & Oncogenic Roles of Activin,
Michael Waters, Univ of Queensland Inhibin & Other TGF Beta-Related
& the Establishment & Maintenance of
GH Signaling Overview Ligands B
Adult Bone
Christin Carter-Su, Univ of Michigan Chair: Alan Schneyer, Massachusetts
John D Bassett, Imperial Coll (UK)
Med Sch Gen Hosp
TR Isoform-Specific Functions in the Heart
Myostatin & Muscle Growth
Onno Bakker, Univ of Amsterdam
Hormonal Control of Neuroplasticity B Se-Jin Lee, Johns Hopkins Univ Sch of Med
(Netherlands)
Chair: Darrell Brann, Inst of Molec Med & BMP Actions on Cartilage & Bone
Genet (Augusta, GA) Karen M Lyons, Univ of California-Los
Regulatory Modifications of Nuclear
Androgen Modulation of Synaptic Receptors B Angeles David Geffen Sch of Med
Plasticity Chair: Susan Logan, New York Univ Activin/TGF-Beta Signaling & the
Neil MacLusky, Helen Hayes Hosp (West Sch of Med Control of Cellular
Haverstraw, NY) Sumoylation of Androgen Receptors Proliferation/Apoptosis
Jorma Palvimo, Univ of Kuopio (Finland) Jean-Jacques Lebrun, Royal Victoria
Hosp/McGill Univ (Canada)

B C T E
13

Scientific Program
Receptor Signaling Cross-Talk B Extension of Human Lifespan & 3:4 5 – 5:15 P M

Chair: Kerry Burnstein, Univ of Miami Sch Prevention of Aging T
Glial Regulation of Neuroendocrine
of Med Chair: Reubin Andres, NIA/NIH
Function B
Progesterone Receptor Cross-Talk with The GH-IGF Axis in Aging: Lessons from
Chair: To Be Announced
Growth Factors Individuals with Exceptional Longevity
Neuroglia & Thyroid Hormone Action
Carol Lange, Univ of Minnesota Cancer Ctr Pinchas (Hassy) Cohen, Univ of California-
Sabrina Diano, Yale Univ Sch of Med
GH Receptor Signaling to Growth Factor Los Angeles
Glial Cells in Reproductive Function
Receptors Aging & Longevity Genes
Sergio Ojeda, Oregon Natl Primate Res Ctr
Stuart Frank, Univ of Alabama-Birmingham Rudi Westendorp, Leiden Univ Med Ctr
Hypothalamic Glial Role in Glucose
RSK Activation of Estrogen Receptors (Netherlands)
Sensing
Deborah Lannigan, Univ of Virginia Aggressive Dietary & Lifestyle
Nicole Sanders, VA Puget Sound Hlth
Approaches to Longevity
Care Syst (Seattle, WA)
The Genetics of Complex Endocrine Samuel Klein, Washington Univ Sch of Med
Disorders T
New Concepts in Bone Biology B
Chair: William Crowley, Harvard Med Modeling Hormone-Dependent (Supported by Quest Diagnostics)
Sch/Massachusetts Gen Hosp Cancers T
Chair: Dana Gaddy, Univ of Arkansas for
Genetics of Type 1 Diabetes Chair: Wayne D Tilley, Univ of
Med Sci
Andrew Paterson, Univ of Toronto/Hosp for Adelaide/Hanson Inst (Australia)
FSH Regulation of Bone Mass
Sick Children Modeling Progesterone Receptor-
Mone Zaidi, Mt Sinai Sch of Med
Whole Genome Association Study of Dependent Cancers
Osteoclast Regulation of Osteoblast
Type 2 Diabetes Eva Lee, Univ of California-Irvine
Function
David Altshuler, Massachusetts Gen Hosp PSA Induces Epithelial-to-Mesenchymal
Steven Teitelbaum, Washington Univ Sch
Genetic Studies in PCOS Transition (EMT) in Prostate Cancer
of Med
Margrit Urbanek, Northwestern Univ Judith Clements, Queensland Univ of Tech
FGF23, Vitamin D3 & Bone
Feinberg Sch of Med (Australia)
Beate Lanske, Harvard Sch of Dental Med
IGF-1 in Prostate & Breast Cancers
Monday, June 4 Shoshana Yakar, Mt Sinai Sch of Med Novel Mechanisms of Hormone
9:3 0 – 11:00 A M Action in Cancer T
Neurosteroid Biosynthesis & Actions Chair: Irma Russo, Fox Chase Cancer Ctr
Compartmentalization of Receptor in the Brain T
Signaling B (Philadelphia, PA)
Chair: Synthia Mellon, Univ of California-
Chair: Mark S Roberson, Cornell Univ Coll Endocrine Resistance in Breast Cancer
San Francisco
of Vet Med Rakesh Kumar, Univ of Texas MD Anderson
Neurosteroid Regulation of Neurogenesis
Caveoli & Signal Transduction Cancer Ctr
in an Animal Model of Alzheimer’s
Michael Lisanti, Thomas Jefferson Univ Epigenetics in Prostate Cancer
Disease
IP3 Receptors & Calcium Signaling Gail Prins, Univ of Illinois-Chicago
Roberta Brinton, Univ of Southern California
Colin W Taylor, Univ of Cambridge (UK) Estrogen Receptors in Lung Cancer
Neurosteroids & Alcohol Interactions in
APS: The First To Arrive Jill M Siegfried, Univ of Pittsburgh
the Brain
Tahir S Pillay, Univ of Cape Town (South
A Leslie Morrow, Univ of North Carolina- Recent Advances in the Regulation of
Africa)
Chapel Hill Beta-Cell Mass B
Neurosteroids & Feeding Chair: Lydia Aguilar-Bryan, Baylor Coll
Emerging Concepts in Testicular
Klaus Ossenkopp, Univ of Western Ontario of Med
Development & Descent T
(Canada) NFATs & Beta-Cell Replication
Chair: Jorma Toppari, Univ of Turku
(Finland) Seung K Kim, Stanford Univ
Tissue Specific Actions of IGF-1 B Sex Steroids & Beta-Cell Survival
Gubernacular Development
Chair: Charles Roberts, Oregon Hlth & Franck Mauvais-Jarvis, Northwestern Univ
John Hutson, Royal Children’s Hosp Res Inst
Sci Univ Feinberg Sch of Med
(Australia)
IGF in the Brain MLK3 & Akt Cross-Talk in Beta-Cell
Developmental Origin of Human
Luis Garcia-Segura, Inst Cajal (Spain) Survival
Testicular Cancer: Environmental &
IGF in the Gastrointestinal Tract Ulupi Jhala, Univ of California-San Diego
Genetic Aspects
Pauline Lund, Univ of North Carolina-
Ewa Rajpert-De Meyts, Univ Hosp of
Chapel Hill RNA & Disease B
Copenhagen
IGF & BMP Cross-Talk in Skeleton Chair: Niketa A Patel, Univ of South
Preservation of Spermatogenesis in
Michael Centrella, Yale Univ Sch of Med Florida Coll of Med
Cryptorchidism
Kolja Kvist, Univ Hosp of Copenhagen Prader-Willi Syndrome: Defects in
Pre-mRNA Processing
Stefan Stamm, Univ of Erlangen (Germany)

14 B C T E
Scientific Program
miRNA & Pancreatic Beta-Cell Function Regulation of Gametogenesis by PIWI- Nuclear Receptor Coregulators B
Markus Stoffel, Rockefeller Univ Interacting RNA/Male Sterility by Miwi Chair: Karen Knudsen, Univ of Cincinnati
Nature’s Own Regulatory Genes Affecting Mutations Coll of Med
Metabolism: miRNA Speaker To Be Announced Roles of Protein-Protein Interactions &
Peter J Leedman, Western Australia Inst Protein Methylation in Nuclear Receptor
Med Res Nongenomic Actions of Steroid Coregulator Function
Hormones B Michael Stallcup, Univ of South
Tuesday, June 5 Chair: Teresita Bellido, Univ of Arkansas for Carolina/Norris Comp Cancer Ctr
9:3 0 – 11:00 A M Med Sci ART-27: A Novel Coactivator for the
Novel Functions of Thyroid Hormone Androgen Receptor
Advances in Thyroid Hormone
Receptors: Beyond Nucleus-Initiated Michael Garabedian, New York Univ
Metabolism B
Transcription Sch of Med
Chair: Valerie Galton, Dartmouth Med Sch
Sheue-Yann Cheng, NCI/NIH Steroid Receptors, Chaperones & the
Deiodinase Knockout Mouse Models
Src Signaling & Progesterone Receptor Development of the Female Reproductive
Donald St Germain, Dartmouth Med Sch
Action Tract
Regulation of Deiodinase by
Dean Edwards, Baylor Coll of Med Edwin Sanchez, Med Univ of Ohio
Ubiquitination
Estrogen Signaling in Vascular Cells
Antonio Bianco, Brigham & Women’s Hosp
Tommaso Simoncini, Univ of Pisa (Italy) Signal Transduction in the
Control of Deiodinase by Selenium
Gonadotrope B
Josef Koehrle, Inst Exp Endo/Charite
Novel Disorders of Water Metabolism: Chair: Ursula Kaiser, Brigham & Women’s
(Germany) There’s Something New in the Hosp/Harvard Med Sch
Water T GnRH Signaling Genomics in
Genetics of Adipocyte Substrate Chair: Chris Thompson, Beaumont Gonadotropes
Metabolism B
Hosp/Royal Coll of Surg in Ireland Med Sch Stuart Sealfon, Mt Sinai Sch of Med
Chair: Rexford Ahima, Univ of
Aquaporin-1 Full Contact Origami: Cellular Trafficking
Pennsylvania Sch of Med
Soren Nielsen, Aarhus Univ Hosp of the GnRH Receptor in Health & Disease
Triglyceride Synthesis & Insulin
(Denmark) P Michael Conn, Oregon Hlth & Sci Univ
Resistance
Syndrome of Inappropriate Antidiuresis Transcriptional Regulation of
Robert V Farese, Jr, J David Gladstone Inst
Stephen Gitelman, Univ of California-San Gonadotropin Genes
(San Francisco, CA)
Francisco Pamela Mellon, Univ of California-
Genetic Defects in Fat Metabolism
Vasopressin Antagonists San Diego
James Ntambi, Univ of Wisconsin-Madison
Florence Wong, Univ of Toronto
Fatty Acid Oxidation in the Periphery &
The Renin-Angiotensin-Aldosterone
Insulin Resistance in Humans
Melanie Gillingham, Oregon Hlth &
3:4 5 – 5:15 P M System T
Mechanisms of Ovarian Function B Chair: Morag Young, Prince Henry’s
Sci Univ
Chair: Raymond J Rodgers, Univ of Inst/Monash Med Ctr (Australia)
Adelaide Med Sch Structural Determinants of Ligand-
IGFs & Cancer T
Intrinsic Mechanisms of Ovarian Dependent Specificity in the
Chair: Terri Wood, New Jersey Med
Function Mineralocorticoid Receptor
Sch/Univ of Med & Dent of New Jersey
JoAnne S Richards, Baylor Coll of Med Peter Fuller, Prince Henry’s Inst/Monash
Inhibition of Oncogenic Actions of IGF-
Ovarian Development & Sex Reversal Med Ctr (Australia)
IR with PPP
Richard Behringer, Univ of Texas MD Interaction of Gonadal Steroids & the
Olle Larsson, Karolinska Inst (Sweden)
Anderson Cancer Ctr RAAS
IGF & IGFBP in Epithelial Tumors
Germ Cell Tumors in the Intersex Gonad Ellen Seely, Brigham & Women’s
Michael Pollack, Lady Davis Res Inst,
Leendert HJ Looijenga, Erasmus Med Ctr Hosp/Harvard Univ
McGill Univ (Canada)
(Netherlands) Mineralocorticoid Actions in Nonclassic
Estrogen, IGF-1 & Cancer
Target Tissues
Eva Surmacz, Temple Univ
Mitochondria in Metabolic Disease T Martin Wehling, Univ of Heidelberg-
Chair: Gerald Shulman, Yale Univ Sch of Mannheim
New Concepts in Male
Reproduction B Med/HHMI
Chair: Philippa T Saunders, Queen’s Med Mitochondrial Genetics & Metabolic
Res Inst (Scotland) Syndrome
Retinoid Signaling & Germ Cell Fate Douglas Wallace, Univ of California-Irvine
Peter Koopman, Univ of Queensland Insulin Regulation & Mitochondrial
The Spermatogonial Stem Cells Niche Metabolism
Paul Cooke, Univ of Illinois-Urbana Kitt F Petersen, Yale Univ Sch of Med
Improving Metabolism in Mitochondria
Ulrik Wisloff, Norwegian Univ Sci & Tech

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15

New Technology Lectures Conversations with Basic Researchers
Scientific Program
new
Incorporate a new technique in the research plan of your next Ask a thought leader about his or her personal experiences in
grant. The New Technology Lecture series provides endocrine science. Targeted specifically to graduate students, fellows, and
investigators with an opportunity to hear from thought leaders in junior faculty, these sessions are intended to be informal, 45-
new, emerging, or evolving fields of scientific discovery. See and minute discussions with leading endocrine investigators.
hear first-hand what an expert has to say about the power and
limitations of a new technology. These sessions will take place on Saturday, June 2 and Sunday,
June 3, or Monday, June 4 and Tuesday, June 5, 1:15 – 2:00 PM.
Check the ENDO Web site for updates on the dates and times
Saturday, June 2 of these sessions.
12:15 - 1:00 P M
Epigenetics Meets Endocrinology
Conversations about the HPA Axis
Shuk-mei Ho, Univ of Cincinnati
Mary Dallman, Univ of California-San Francisco
Sunday, June 3 Conversations with the Editor-in-Chief of Molecular
12:15 - 1:00 P M Endocrinology
Comparative Oncogenomics for Gene Discovery (Second- John A Cidlowski, NIEHS/NIH
Generation Microarrays) Conversations about Cell Signaling
Arul Chinnaiyan, Univ of Michigan Med Sch Anthony R Means, Duke Univ Med Ctr
Monday, June 4 Conversations about Prolactin & Growth Hormone
12:15 - 1:00 P M Paul A Kelly, Fac Med Necker (France)
Bioinformatics & Cancer: An Essential Alliance Conversations about Thyroid & Nuclear Hormone Action
Joaquin Dopazo, Centro de Investigacion Gregory A Brent, VA Greater LA Hlthcare
Principe Felipe (Spain)
Conversations about Diabetes
Derek LeRoith, Mt Sinai Sch of Med
Conversations about Calcium & Bone
Henry M (Hank) Kronenberg, Massachusetts Gen Hosp
Conversations about Nuclear Receptor Biology
Keith Yamamoto, Univ of California-San Francisco
Conversations on Steroidogenesis
Carole R Mendelson, Univ Texas SW Med Ctr-Dallas
Conversations with the Editor-in-Chief of Endocrinology
Jeffrey Pessin, State Univ of New York
Conservations about the HPG Axis & Neuroendocrinology
Robert Steiner, Univ of Washington

16 B C T E
CLINICAL SCIENCE & PRACTICE SESSIONS
Scientific Program
Symposia Thyroid Autoimmunity & Pregnancy C
Chair: Rosalind Brown, Children’s Hosp
Hypopituitarism in Long-Term
Survivors of Childhood Cancer C
(Boston, MA) (Supported by Pfizer, Inc.)
Saturday, June 2 Thyroid Autoimmunity & Pregnancy Loss Chair: Charles Sklar, Memorial Sloan-
9:3 0 – 11:00 A M Alex Stagnaro-Green, Univ of Med & Dent Kettering Cancer Ctr
Central & Peripheral Actions of of New Jersey Who & How To Test for Hypopituitarism
Ghrelin T Fetal Microchimerism & Thyroid Helena Gleeson, Christie Hosp (UK)
Chair: Ezio Ghigo, Univ of Turin/Osped Autoimmunity Risks & Benefits of GH Therapy
Molinette (Italy) Klaus Badenhoop, Univ Hosp Frankfurt am Anders Juul, Rigshospitalet (Denmark)
Central & Peripheral Effects of Ghrelin: Main (Germany) Pituitary-Gonadal Function
Interaction with AMPK Maternal Thyroid Function & Outcome W Hamish Wallace, Royal Hosp for Sick
Marta Korbonits, St Bartholomew’s Hosp (UK) of Pregnancy Children (Scotland)
Regulation of GH Secretion John Lazarus, Cardiff Univ Sch of Med (UK)
Michael Thorner, Univ of Virginia Hlth Syst Mouse Models of Nuclear Receptor-
Gastrokinetic Effects Update on Bariatric Surgery C Related Diseases T
Theo Peeters, Katholieke Univ Leuven (Supported by Sanofi-Aventis) Chair: Kathleen Ann Mahon, Baylor Coll
(Belgium) Chair: Diva De Leon, Children’s Hosp of of Med
Philadelphia Oncogenic AR Mutation
CRH: 25 Years Later T Clinical Approaches to the Bariatric Wayne Tilley Univ of Adelaide/Hanson Inst
Chair: WylieVale, Salk Inst Surgical Patient Xenobiotic Receptors & Immune
CRH in Early-Life Stress & H-P-A Axis George Bray, Louisiana State Univ Dysfunction
Neuroplasticity Pennington Biomed Ctr Bruce Blumberg, Univ of California-Irvine
Tallie Baram, Univ of California-Irvine Bariatric Surgery: Eligibility & Methods Kennedy’s Disease: Mouse Models,
Physiological Functions of Urocortin 2 Bruce Wolfe, Oregon Hlth Sci Univ Molecular Mechanisms & Therapeutic
Alon Chen, Weizmann Inst of Sci (Israel) Metabolic Consequences of Bariatric Strategies
Urocortins in Cardiovascular Health & Surgery Andrew Lieberman, Univ of Michigan
Disease Karen Foster-Schubert, VA Puget Sound Med Sch
A Mark Richards, Univ of Otago (New Hlth Care Syst (Seattle, WA)
Zealand) Novel Genes in Thyroid Cancer T
What’s New in Turner’s Syndrome? C (Supported by Genzyme Corporation)
New Insights into Phosphate (Supported by Eli Lilly & Company) Chair: Ronald Koenig, Univ of Michigan
Regulation in Health & Disease T Chair: Josephine Kasa-Vubu, Univ of Med Ctr
Chair: Suzanne Jan De Beur, Johns Hopkins Michigan Hlth Sys MCIP-1 & Thyroid Cancer Metastases
Univ Sch of Med Genetic Basis of Anomalies Matthew Ringel, Ohio State Univ
Regulation of Phosphate Metabolism: Judith Ross, Jefferson Med Coll Role of microRNAs in Follicular Thyroid
Normal Physiology & Pathophysiology of (Philidelphia, PA) Carcinogenesis
Disease Controversies in Therapy Charis Eng, Cleveland Clin
Sherri-Ann Burnett, Massachusetts Gen Hosp Cheri Deal, St Justine Hosp (Canada) Pituitary Tumor Transforming Gene
Role of FGF23 & Other Phosphatonins in Morbidity & Mortality (PTTG) Promotes Thyroid Cancer
Disorders of Phosphate Metabolism Claus Gravholt, Aarhus Univ Hosp Progression
Anthony Portale, Univ of California-San (Denmark) Christopher McCabe, Univ of Birmingham
Francisco (UK)
Insights into the Regulation of Phosphate 3:4 5 – 5:15 P M
Metabolism Using Transgenic & Ovarian Failure C
Knockout Mice Disparities in Endocrine Health of
Chair: Corrine K Welt, Massachusetts Gen
Rajiv Kumar, Mayo Clin Minorities C
Hosp
Chair: James Gavin III, MicroIslet, Inc
MIS/AMH as a Marker of Ovarian
Polycystic Ovary Syndrome & (San Diego, CA)
Function
Infertility C Disparities in the Pathophysiology &
Axel P Themmen, Erasmus Med Ctr
Chair: Sabrina Gill, St Paul’s Hosp (Canada) Management of Hypertension: Focus on
(Netherlands)
Metformin/No Metformin: PPCOS African Americans
Autoimmune Mechanisms in Premature
Results Crystal Gadegbeku, Univ of
Ovarian Failure
Evan R Myers, Duke Univ Med Ctr Michigan/Simpson Mem Inst
Alberto Falorni, Univ of Perugia (Italy)
Use of Aromatase Inhibitors in PCOS Treatment of Obesity: Does Culture Matter?
The Fragile X Premutation & Premature
Robert F Casper, Toronto Ctr for Advanced Shiriki Kumanyika, Univ of Pennsylvania
Ovarian “Failure”
Sch of Med
Repro Tech (Canada) Lawrence M Nelson, NICHD/NIH
Health of Minority Children in the US in
Oocyte Development in Women with
2007 & Beyond
PCOS
Renee Jenkins, Howard Univ Coll of Med
Daniel A Dumesic, Reprod Med & Infertility (Washington, DC)
Assoc (Woodbury, MN)
Page content as of January 20, 2007 – for up-to-date information, visit www.endo-society.org/endo/program/index.cfm?view=clinical

Regulation of Puberty T Therapy of Carcinoid Tumors & the American Thyroid Association
Scientific Program
Chair: Selma Feldman Witchel, Children’s Carcinoid Syndrome Management Guidelines for Thyroid
Hosp of Pittsburgh Larry Kvols, Univ of South Florida Nodules & Thyroid Cancer
The Impact of Endocrine-Disrupting GEP Neuroendocrine Tumors in MEN-I Ernest Mazzaferri, Univ of Florida
Chemicals on Female Puberty & Non–MEN-I Patients Molecular Approaches to New Treatment
Jean Bourguignon, Univ of Liege (Belgium) Geoffrey B Thompson, Mayo Clin Modalities
Evolution of Puberty James Fagin, Memorial Sloan-Kettering
Mark Hanson, Univ of Southampton/ The Clinical Future for Vitamin D & Its Cancer Ctr (NY)
Princess Anne Hosp (UK) Analogy C Thyroid Cancer Clinical Trials:
Role of GPR54 Mutations in Pubertal Chair: Roger Bouillon, Katholieke Univ An Update
Disorders Leuven (Belgium) Manisha Shah, Ohio State Univ
Ana Latronico, Hosp das Clinicas da Fac de Regulation of Innate Immune Function by
Medicina da USP (Brazil) Vitamin D & Its Analogues New Directions in Male
John White, McGill Univ (Canada) Hypogonadism C
Sunday, June 3 The Potential Role for Vitamin D & Its (Supported by Solvay)
9:3 0 – 11:00 A M Analogues in Diabetes Management Chair: John K Amory, Univ of Washington
Anastassios Pittas, New England Med Ctr Med Ctr
Clinical Topics in Cardiovascular
(Boston, MA) Sex Steroid Actions in Male Skeleton
Endocrinology C
Role of Vitamin D & Its Analogues in Dirk Vanderschueren, Katholieke Univ
(Supported by Abbott Diagnostics)
Cancer Prevention & Treatment Leuven (Belgium)
Chair: Gail Adler, Brigham & Women’s
David Feldman, Stanford Univ Med Ctr Therapeutic Promise of Selective
Hosp/Harvard Univ
Androgen Receptor Modulators
Clinical Uses of Aldosterone Antagonists
Riccardo Rocha, Novartis Pharmaceuticals 3:4 5 – 5:15 P M (SARMs): Preclinical & Clinical Proof-
Effect of Diet on Diabetes & of-Concept Studies
Corp (East Hanover, NJ)
Metabolism C James Dalton, GTx, Inc (Memphis, TN)
Cardiovascular Pathogenesis of Pre-
(Supported by Sanofi-Aventis) Gonadal Steroids & Cognition in Elderly
Eclampsia
Chair: Kwame Osei, Ohio State Univ Men
S Ananth Karumanchi, Beth Israel
Med Ctr Lenore Launer, NIA/NIH
Deaconess Med Ctr/Harvard Med Sch
New Clinical Considerations in Renin- Is There a Case for the Glycemic Index?
David Jenkins, Univ of Toronto Pathophysiology & Treatment of
Angiotensin Blockade
Does Trans Fat Intake Contribute to Secondary Osteoporosis C
Robert Carey, Univ of Virginia Hlth Syst
Heart Disease & Diabetes? Chair: Ghada El-Hajj Fulheihan, Amer
Martijn Katan,Virje Univ Amsterdam Univ of Beirut Med Ctr
Control of GnRH: The Role of
Genetic Studies in Expanding Our Carbohydrate, Protein & Fat: Getting the Bone Loss Associated with Breast Cancer
Understanding of Neuroendocrine Proportions Right Therapies & Its Management
Mechanisms T Bonnie J Brehm, Univ of Cincinnati Richard Eastell, N Gen Hosp/Univ of
Chair: Kathleen Whitlock, Cornell Univ Sheffield (UK)
Lessons from GPR54 Mutations in Growth Hormone in Aging T Osteoporosis after Organ Transplantation
Idiopathic Hypogonadotropic Chair: Barbara C Hansen, Univ of South Elizabeth Shane, Columbia Univ Coll of
Hypogonadism Florida-Tampa Phys & Surg
Nicolas de Roux, Hosp Robert Debra Maintenance of Cognitive Function in Bone Loss Associated with Inflammatory
(France) Disease & Its Therapies
the Aging Brain by GH
Novel Genes Causing Kallmann’s Steven Goldring, Hosp for Special Surg (NY)
William Sonntag, Wake Forest Univ Sch
Syndrome of Med
Nelly Pitteloud, Massachusetts Gen Hosp The Genetics of Complex Endocrine
GH-Regulated Genes as Markers of Aging Disorders T
Analysis of Kallmann’s Syndrome through John Kopchick, Ohio Univ/Edison Biotech
the Prism of Structural Biology Chair: William Crowley, Harvard Med
Inst Sch/Massachusetts Gen Hosp
Moosa Mohammadi, New York Univ GH & Lifespan in Mammals
Med Ctr Genetics of Type 1 Diabetes
Holly Brown-Borg, Univ of North Dakota Andrew Paterson, Univ of Toronto/Hosp for
Neuroendocrine Tumors of the Sick Children
Gastroenteropancreatic (GEP) Tract C Whole Genome Association Study of
Management of Differentiated Thyroid
Chair: Wouter de Herder, Erasmus Med Ctr Type 2 Diabetes
Cancer C
(Netherlands) David Altshuler, Massachusetts Gen Hosp
Chair: Johannes Smit, Leiden Univ Med Ctr
Pathology of GEP Neuroendocrine Genetic Studies in PCOS
(Netherlands)
Tumors Margrit Urbanek, Northwestern Univ
Guido Rindi, Univ Degli Studi Di Parma Feinberg Sch of Med
(Italy)

www.endo-society.org/endo/program/index.cfm?view=clinical
18 B C T E

Monday, June 4 Neurosteroid Regulation of Neurogenesis Estrogen Receptors in Lung Cancer
Scientific Program
9:3 0 – 11:00 A M in an Animal Model of Alzheimer’s Disease Jill M Siegfried, Univ of Pittsburgh
Roberta Brinton, Univ of Southern California
Controversies in the Management of
Neurosteroids & Alcohol Interactions in Optimal Treatment for Lipid Disorders C
Pituitary Disease C
the Brain (Supported by Pfizer, Inc.)
Chair: Anne Klibanski, Massachusetts
A Leslie Morrow, Univ of North Carolina- Chair: Paulos Berhanu, Wayne State Univ
Gen Hosp
Chapel Hill Sch of Med
Sellar Cysts
Neurosteroids & Feeding Optimal Goals for LDL: What Is the
Edward Laws, Univ of Virginia
Klaus Ossenkopp, Univ of Western Ontario Evidence?
Pituitary Stalk Lesions
(Canada) Alan Chait, Univ of Washington
Mark Molitch, Northwestern Univ Feinberg
Should Triglyceride Be Targeted To
Sch of Med
Polycystic Ovary Syndrome Is Not Reduce Cardiovascular Disease Risk?
Prolactin: Not Just for Lactation
Just a Reproductive Disorder C Helen M Calhoun, Conway Inst (Ireland)
Annice Mukherjee, Christie Hosp (UK)
Chair: Andrea E Dunaif, Northwestern Strategies for Raising HDL levels
Univ Feinberg Sch of Med H Bryan Brewer, Jr, MedStar Res
Emerging Concepts in Testicular
Development & Descent T Cardiovascular Risks in PCOS Inst/Washington Hosp Ctr (Washington, DC)
Chair: Jorma Toppari, Univ of Turku David S Guzick, Univ of Rochester Med Ctr
(Finland) Sleep Apnea in PCOS Perimenopausal Symptoms C
Gubernacular Development David A Ehrmann, Univ of Chicago Chair: Rogerio Lobo, Columbia Univ
John Hutson, Royal Children’s Hosp Res Inst PCOS & Seizure Disorders Med Ctr
(Australia) Martha J Morrell, Stanford Univ Pathophysiology of Menopausal Hot
Developmental Origin of Human Flashes
Weight Loss Maintenance: Preventing Robert Freedman, Wayne State Univ
Testicular Cancer: Environmental &
Weight Regain C Cognitive Changes in Menopause & the
Genetic Aspects
(Supported by Sanofi-Aventis) Effects of Treatment
Ewa Rajpert-De Meyts, Univ Hosp of
Chair: Karen Foster-Schubert, VA Puget Pauline Maki, Univ of Chicago-Illinois
Copenhagen
Sound Hlth Care Sys/Univ of Washington The Perimenopause: Interrelated
Preservation of Spermatogenesis in
Behavioral Aspects of Weight Regain Symptoms & Responses to Treatment
Cryptorchidism
Suzanne Phelan, Brown Univ/The Miriam Hadine Joffe, Massachusetts Gen Hosp
Kolja Kvist, Univ Hosp of Copenhagen
Hosp
Physiology of the Reduced Obese State Pheochromocytoma & Paraganglioma C
Extension of Human Lifespan &
Holly Wyatt, Univ of Colorado Hlth Sci Ctr Chair: Shern Chew, St Bartholomew’s Hosp
Prevention of Aging T
Pharmacotherapy to Avoid Weight Regain (UK)
Chair: Reubin Andres, NIA/NIH
Robert Lustig, Univ of California-San Hereditary Paraganglioma: An Emerging
The GH-IGF Axis in Aging: Lessons from
Francisco Link between Krebs Cycle & Hypoxic
Individuals with Exceptional Longevity
Signaling
Pinchas (Hassy) Cohen, Univ of California-
Los Angeles
3:4 5 – 5:15 P M Bora Baysal, Univ of Pittsburgh
Long-Term Consequences of Early Genetic Regulation of Succinate
Aging & Longevity Genes
Glucocorticoid Exposure C Dehydrogenase & Paraganglioma
Rudi Westendorp, Leiden Univ Med Ctr
Chair: Sharon Oberfield, Columbia Univ Susceptibility
(Netherlands)
Coll of Phys & Surg Patricia Dahia, Univ of Texas Hlth Sci Ctr
Aggressive Dietary & Lifestyle
Early Cortisol Biosynthesis by the Human Novel Approaches to Imaging & Therapy
Approaches to Longevity
Fetal Adrenal Cortex During Sexual for Pheochromocytoma & Paraganglioma
Samuel Klein, Washington Univ Sch of Med
Differentiation Wouter de Herder, Erasmus Med Ctr
Neil Hanley, Univ of Southampton (UK) (Netherlands)
Modeling Hormone-Dependent
High-Dose Glucocorticoid Administration
Cancers T
in Late Gestation Tuesday, June 5
Chair: Wayne D Tilley, Univ of
Keith J Barrington, Royal Victoria Hosp 9:3 0 – 11:00 A M
Adelaide/Hanson Inst (Australia)
(Canada)
Modeling Progesterone Receptor- Cushing’s Syndrome C
Long-Term Follow-Up of Fetuses
Dependent Cancers Chair: Beverly MK Biller, Massachusetts
Prenatally Treated for CAH
Eva Lee, Univ of California-Irvine Gen Hosp
Svetlana Lajic, Imperial Coll (UK)
PSA Induces Epithelial-to-Mesenchymal Endogenous Hypercortisolism: Not your
Transition (EMT) in Prostate Cancer Mentor’s Cushing’s Syndrome
Novel Mechanisms of Hormone
Judith Clements, Queensland Univ of Tech Action in Cancer T James Findling, St Luke’s Med Ctr
(Australia) Chair: Irma Russo, Fox Chase Cancer Ctr (Milwaukee, WI)
IGF-1 in Prostate & Breast Cancers (Philadelphia, PA) Role of cAMP/PKA Signaling Pathway in
Shoshana Yakar, Mt Sinai Sch of Med Endocrine Resistance in Breast Cancer Cushing’s Syndrome
Rakesh Kumar, Univ of Texas MD Anderson Constantine Stratakis, NICHD/NIH
Neurosteroid Biosynthesis & Actions Molecular Genetics of Adrenal Cortical
Cancer Ctr
in the Brain T Page content as of January 20, 2007 – for up-to-date information visit
Carcinoma
Epigenetics in Prostate Cancer
Chair: Synthia Mellon, Univ of California-
www.endo-society.org/endo06/Program/clinical.php Jerome Bertherat, CHU Cochin (France)
Gail Prins, Univ of Illinois-Chicago
San Francisco

Scientific Program
IGFs & Cancer T Steroid Treatment & What To Do If Endocrine Updates

Chair: Terri Wood, New Jersey Med Steroids Fail
Sch/Univ of Med & Dent of New Jersey Claudio Marcocci, Univ of Pisa (Italy) “The Year In” Series new
Inhibition of Oncogenic Actions of IGF- “The Year In” series of lectures calls upon
IR with PPP Mitochondria in Metabolic Disease T thought leaders in endocrine clinical
Olle Larsson, Karolinska Inst (Sweden) Chair: Gerald Shulman, Yale Univ Sch of research to present a review of the most
IGF & IGFBP in Epithelial Tumors Med/HHMI important published discoveries of the year.
Michael Pollack, Lady Davis Res Inst, Mitochondrial Genetics & Metabolic
McGill Univ (Canada) Syndrome Saturday, June 2
Estrogen, IGF-1 & Cancer Douglas Wallace, Univ of California-Irvine 12:3 0 – 1:15 P M
Eva Surmacz, Temple Univ Insulin Regulation & Mitochondrial
The Year in Thyroidology
Metabolism
(Supported by Abbott Laboratories)
Incretin-Based Therapies in Diabetes Kitt F Petersen, Yale Univ Sch of Med
E Chester (Chip) Ridgway, Univ of
Mellitus: Effects & Controversies C Improving Metabolism in Mitochondria
Colorado Hlth Sci Ctr
(Supported by Merck & Co., Inc.) Ulrik Wisloff, Norwegian Univ Sci & Tech
Chair: Daniel Drucker, Univ of Toronto
Gen Hosp New Diabetes Technologies C Monday, June 4
The Role of Incretins in Glucose Control (Supported by Novo Nordisk Inc.) 12:3 0 – 1:15 P M
Jens J Holst, Univ of Copenhagen Chair: Bernard Zinman, Mt Sinai Hosp (NY) The Year in Pituitary
GLP-1 & Its Analogs Combined Insulin Pump/Glucose-Sensing (Supported by Altus Pharmaceuticals)
Edward Horton, Joslin Diab Ctr Meters: Role in Diabetes Management Shlomo Melmed, Cedars-Sinai Med Ctr
DPP-IV Inhibitors Christopher Saudek, Johns Hopkins Univ
Julio Rosenstock, Dallas Diab Ctr Inhaled Insulin: When, Where & How? Tuesday, June 5
Jay Skyler, Univ of Miami Diab Res Inst 12:3 0 – 1:15 P M
New & Emerging Therapies for Current Indications for Islet vs Whole
The Year in Male Reproduction
Osteoporosis C Pancreas Transplantation
David Handelsman, ANZAC Res Inst/Univ
(Supported by Eli Lilly & Company) Michael Rickels, Univ of Pennsylvania
of Sydney
Chair: Carlos Isales, Med Coll of Georgia
Targeting the Wnt Pathway Sex Determination & Differentiation C
Jennifer Westendorf, Univ of Minnesota Chair: Maria New, Mt Sinai Sch of Med
Effectiveness of Strontium Ranelate on Legacy of the Late John Money:
Endocrine Debates
The practice of endocrinology often
Skeletal Metabolism Controversies in Sexual Assignment
involves providing clinical care in areas
Pierre Marie, Hopital Lariboisiere (France) Melvin Grumbach, Univ of California-San
where there is not yet consensus on the
PTH/PTHrP Receptor Targeted Therapies Francisco
ideal diagnosis or treatment protocol. The
Speaker To Be Announced Sex Determination, Differentiation &
Annual Meeting Steering Committee has
Identity
included four of these exciting Endocrine
Novel Disorders of Water Metabolism: Amy Wisniewski, Johns Hopkins Univ
There’s Something New in the Water T Debates to address such areas in this year’s
Testicular Anti-Mullerian Hormone:
Chair: Chris Thompson, Beaumont annual meeting.
History, Genetics, Regulation & Clinical
Hosp/Royal Coll of Surg in Ireland Med Sch Applications
Aquaporin-1 Nathalie Josso, INSERM U493, Inst Saturday, June 2
Soren Nielsen, Aarhus Univ Hosp Cytokines (France) 11:15 A M – 12:15 P M
(Denmark) What To Do with the Patient with Type
Syndrome of Inappropriate Antidiuresis The Renin-Angiotensin-Aldosterone 2 DM Failing on Metformin (HbA1C =
Stephen Gitelman, Univ of California-San System T 7.2%)?
Francisco Chair: Morag Young, Prince Henry’s Moderator: Robert Rizza, Mayo Clin
Vasopressin Antagonists Inst/Monash Med Ctr (Australia) Treatment Strategy 1: Add an Insulin
Florence Wong, Univ of Toronto Structural Determinants of Ligand- Sensitizer
Dependent Specificity in the Robert Ratner, MedStar Res Inst
3:4 5 – 5:15 P M Mineralocorticoid Receptor (Washington, DC)
Graves’ Ophthalmopathy C Peter Fuller, Prince Henry’s Inst/Monash Treatment Strategy 2: Add Insulin
Chair: Elsie Allen, Bristol-Myer Squibb Co Med Ctr (Australia) David Nathan, Massachusetts Gen Hosp
(Princeton, NJ) Interaction of Gonadal Steroids & the
Antoimmunity Against Orbital Antigens: RAAS
Is It the TSH Receptor or the IGF-1 Ellen Seely, Brigham & Women’s
Receptor? Hosp/Harvard Univ
Rebecca Bahn, Mayo Clin Mineralocorticoid Actions in Nonclassic
Is Steroid Prophylaxis Useful in the Target Tissues
Prevention of Eye Changes after I131 Martin Wehling, Univ of Heidelberg-
Therapy? Mannheim
Luigi Bartalena, Univ of Insubria (Italy)

Sunday, June 3 Adrenal Osteogenesis Imperfecta: New
Scientific Program
11:15 A M – 12:15 P M Congenital Adrenal Hyperplasia Genetic & Clinical Insights
Deborah Merke, NICHD/NIH Alan Burshell, Ochsner Clin Fdn (New
What Should Be the Target for
Glycemic Control in the ICU? E Orleans, LA)
Cushing’s Syndrome
Moderator: John Buse, Univ of North John Newell-Price, Sheffield Univ (UK) Osteoporosis Management in Men
Carolina Sch of Med (Supported by Eli Lilly & Company)
Treatment Strategy 1: To Less than 110 Cushing’s Syndrome in Children & Benjamin Leder, Massachusetts Gen Hosp
mg/dL Adults
Greet Van den Berghe, Katholieke Univ Ashley Grossman, St Bartholomew’s Hosp (UK) Screening for & Treating Vitamin D
Leuven (Belgium) Deficiency: What’s the Target?
Treatment Strategy 2: To 120–150 mg/dL Disorders of Steroidogenesis, Other (Supported by Quest Diagnostics)
John Miles, Mayo Clin than 21-Hydroxylase Daniel Bikle, Univ of California-San
Kenji Fujieda, Asahikawa Med Coll (Japan) Francisco VA Med Ctr
Monday, June 4 Evaluation of Adrenal Function in Use of Bone Markers in Osteoporosis
11:15 A M – 12:15 P M the ICU (Supported by Eli Lilly & Company)
What Is the Role of FNA in the Mark Cooper, Univ of Birmingham (UK) Richard Eastell, Northern Gen Hosp/Univ of
Management of the Thyroid Nodule: Sheffield (UK)
Case 1— Incidentally Discovered Inherited Adrenal Disease
Solitary Thyroid Nodule; Case 2— John Achermann, Inst of Child Hlth/Univ Diabetes
Euthyroid Multinodular Goiter E Coll London (UK) Diabetes & Pregnancy
Moderator: David Cooper, Sinai Hosp of Boyd Metzger, Northwestern Univ Med Sch
Baltimore Management of the Adrenal
Treatment Strategy 1: Selective Use of Incidentaloma Diabetes Mellitus in African-American
FNA John Connell, Univ of Glasgow (Scotland) Children & Adolescents
Susan Mandel, Univ of Pennsylvania (Supported by Eli Lilly & Company)
Metastatic Pheochromocytoma
Treatment Strategy 2: FNA for All Gabriel Uwaifo, MedStar Res Inst
Karel Pacak, NICHD/NIH
Nodules (Washington, DC)
Bryan McIver, Mayo Clin Mineralocorticoid Hypertension
Diabetes: When & How To Use Insulin
Paul Stewart, Univ of Birmingham (UK)
(Supported by Eli Lilly & Company)
Tuesday, June 5
Nelson’s Syndrome & Cushing’s David Nathan, Harvard Med
11:15 A M – 12:15 P M Sch/Massachusetts General Hosp
Disease
Is There a Role for DHEA Xavier Bertagna, Hopital Cochin (France)
Replacement Therapy? E Diabetic Neuropathy
Moderator: D Lynn Loriaux, Oregon Hlth Nonclassical Congenital Adrenal Eva Feldman, Univ of Michigan
Sci Univ Hyperplasia in Adults
Yes, There Is a Role for DHEA Ricardo Azziz, Cedars-Sinai Med Ctr Effect of Diabetes Treatments on
Replacement Therapy Pancreatic Function
Wiebke Arlt, Univ of Birmingham Pheochromocytoma Robert Zimmerman, Cleveland Clin
No, There Is No Role for DHEA Shern Chew, St Bartholomew’s Hosp (UK)
Hypoglycemia: Challenging Cases
Replacement Therapy Primary Aldosteronism F John Service, Mayo Clin
Richard Auchus, Univ of Texas SW Med Ctr
Michael Stowasser, Princess Alexandra Hosp
Incretins & DPP-IV Inhibitors: Uses &
(Australia)
Pitfalls in Treating Diabetics
Meet-the-Professor Bone/ Calcium Daniel Drucker, Mt Sinai Hosp
Bone Loss in Transplantation Patients
Sessions Elizabeth Shane, Columbia Univ Coll of New Drugs & Diabetes Risk:
Hear first hand from recognized thought Antipsychotic & Antiretroviral Agents
Phys & Surg
leaders in endocrine practice. The Meet- Samuel Dagogo-Jack, Univ of Tennessee-
the-Professor Sessions will include expert Hyperparathyroidism Memphis
speakers in all of these endocrine practice (Supported by Quest Diagnostics)
areas: adrenal, bone/calcium, diabetes, Novel Approaches to Treatment of
John Bilezikian, Columbia Univ Coll of Phys
female & male reproduction, obesity/lipids, Diabetes Complications
& Surg
pediatrics, pituitary, thyroid, and miscella- (Supported by Takeda Pharmacueticals North
neous categories. Hypocalcemia America, Inc.)
Bart Clarke, Mayo Clin Byron Hoogwerf, Cleveland Clin Fdn

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21

Transplant-Induced Diabetes Controversies in the Metabolic Pituitary
Scientific Program
Elias Siraj, Temple Univ Hosp Syndrome Acromegaly

(Philadelphia, PA) Adi Mehta, Cleveland Clinic Fdn William Drake, St Bartholomew’s Hosp (UK)
Use & Pitfalls of Continuous Glucose Pediatric Obesity Adult Growth Hormone Replacement
Monitoring Robert Lustig, Univ of California- (Supported by Novo Nordisk Inc.)
(Supported by Medtronic Minimed, Inc.) San Francisco Andrew Hoffman, VA Palo Alto Hlth Care
Irl Hirsch, Univ of Washington Med Ctr Syst (Palo Alto, CA)
The Surgical Problems with Bariatric
Young Adults with Diabetes Surgery Adult Growth Hormone Deficiency
James Lane, Univ of Nebraska Med Ctr Geoffrey Thompson, Mayo Clinic (Supported by Novo Nordisk Inc.)
Female Reproduction Jens S Christiansen, Aarhus Sygehus
Treatment of Lipid Disorders
Amenorrhea (Denmark)
Molly Carr, Northwestern Univ Feinberg
Shala Nader-Eftekhari, Univ of Texas Med Sch of Med & Lisa Tannock, Univ of Growth Hormone in Transition
Sch (Houston, TX) Kentucky (Supported by Eli Lilly & Company)
Evaluation of Adrenarche Jens O Jorgensen, Aarhus Kommunehospital
Treatment of Obesity
Sharon Oberfield, Columbia Univ Coll of (Denmark)
Jonathan Purnell, Oregon Hlth & Sci Univ
Phys & Surg Pituitary Surgery
Work-Up & Treatment of the Morbidly
Brooke Swearingen, Massachusetts Gen Hosp
How To Diagnose PCOS Obese Patient
Janet Hall, Massachusetts Gen Hosp Holly Wyatt, Univ of Colorado Hlth Sci Ctr Postoperative Pituitary Assessment
A Brew Atkinson, Royal Victoria Hosp-
Hypertension in Pregnancy Pediatrics
Belfast (Ireland)
Ellen Seely, Brigham & Women’s Hosp Ambiguous Genitalia
Marco Rivarola, Garrahan Pediat Hosp Prolactinoma in Pregnancy
Management of Primary Ovarian (Argentina)
Failure Marcelo Bronstein, Hosp das Clin/Univ of
Corrine Welt, Massachusetts Gen Hosp Sao Paulo (Brazil)
Aromatase Inhibitors in Pediatric
Endocrinology SIADH
Menstrual Disorders in Adolescents Nelly Mauras, Nemours Children’s Clin
Catherine Gordon, Children’s Hosp Chris Thompson, Beaumont Hosp/Royal
(Jacksonville, FL) Coll of Surg in Ireland
(Boston, MA)
Congenital Adrenal Hyperplasia in Thyroid
Postmenopausal ERT: Issues & Newborns Aggressive & Metastatic Thyroid Cancer
Strategies Perrin White, Univ of Texas SW Med Ctr Kenneth Ain, Univ of Kentucky Med Ctr
(Supported by Solvay)
Speaker To Be Announced Controversies in the Management of Amiodarone-Induced Thyrotoxicosis
Hyperthyroidism in Children Wilmar Wiersinga, Univ of Amsterdam
Male Reproduction Donald Zimmerman, Children’s Mem Hosp
Diagnosis of Male Hypogonadism (Chicago, IL) Drug-Induced Thyroid Disorders
(Supported by Solvay) (Supported by Abbott Laboratories)
Bradley Anawalt, VA Puget Sound Hlth Evaluation of Short Stature Mary Samuels, Oregon Hlth & Sci Univ
Sci Ctr (Seattle, WA) Peter Clayton, Royal Manchester Children’s
Hosp Medullary Thyroid Carcinoma
Testosterone Therapy of Older Men: (Supported by AstraZeneca)
When Is It Justified (If Ever)? Precocious Puberty Douglas Ball, Johns Hopkins Univ
Shalender Bhasin, Boston Univ Sch of Med Berenice Mendonca, Univ Sao Paulo Fac Sch of Med
Med (Brazil)
Treatment of Male Hypogonadism New Treatments for Thyroid Cancer
(Supported by Solvay) Turner’s Syndrome: From Childhood (Supported by Genzyme Corporation)
Ebo Nieschlag, Univ of Muenster (Germany) to Adulthood Steven Sherman, Univ of Texas MD
(Supported by Eli Lilly & Company) Anderson Cancer Ctr
Obesity/ Lipids Claus Gravholt, Aarhus Univ Hosp
African-American Women, Metabolic (Denmark) Perplexing Thyroid Function Tests
Syndrome & the National Cholesterol Krishna Chatterjee, Univ of Cambridge/
Education Program Type 2 Diabetes in Children Addenbrooke’s Hosp (UK)
Ferenando Ovalle, Univ of Alabama- Silva Arslanian, Children’s Hosp of Pittsburgh Mark Gurnell, Univ of Cambridge (UK)
Birmingham
What To Do with the Small-for- Surgical Management of Thyroid Cancer
Cases from an Obesity Clinic Gestational-Age Child Quan-Yang Duh, San Francisco VA Med Ctr
Rexford Ahima, Univ of Pennsylvania Sch Maria V Mericq, Hosp San Borja-Arriaran
of Med (Chile) Thyroid Cancer
(Supported by Abbott Laboratories)
Kenneth Burman, Washington Hosp Ctr

Thyroid Disease in Pregnancy & Continuing Medical Friday, June 1
Scientific Program
Postpartum 1:3 0 – 5:3 0 P M
(Supported by Abbott Laboratories) Education Services Using CGM to Improve Diabetes Care:
Alex Stagnaro-Green, Univ of Med & Dent Continuing Medical Education Services A Review of the Latest Research &
of New Jersey (CMES), a division of The Endocrine Clinical Practice Strategies
Society, develops a variety of superior (Cosponsored by The Endocrine Society &
Thyroid Hormone Therapy: Why Some continuing medical education activities The Juvenile Diabetes Research Foundation;
Patients Are Unhappy that are presented as ancillary symposia to Supported by Abbott Diabetes Care &
(Supported by Abbott Laboratories) the ENDO Meeting. Medtronic Minimed, Inc.)
David Cooper, Sinai Hosp of Baltimore Program Directors: Jennifer Larsen, MD &
The Endocrine Society is accredited by
Thyroid Nodules the Accreditation Council for Continuing Aaron Kowalski, PhD
Stephanie Fish, Univ of Pennsylvania Medical Education (ACCME) to provide
continuing medical education for 6:3 0 – 9:3 0 P M
Thyroiditis: Unusual Causes/Unusual physicians. Endocrine Sequelae in Post-Traumatic
Cases Brain Injury
Robert Smallridge, Mayo Clin-Jacksonville CMES programs are developed by The (Supported by Novo Nordisk Inc.)
Endocrine Society’s Special Programs and Program Director: Anne Klibanski, MD
Unusual Causes of Hypothyroidism CME Advisory Committees, ensuring
Paolo Beck-Peccoz, Inst of Endo Scis (Italy) that content is balanced, free from Saturday, June 2
commercial bias, and maintains the 6:00 – 8:00 A M
Miscellaneous Society’s standard of scientific integrity.
Endocrine Evaluation of the Patient The Role of Inhaled Insulin in Current
These programs are supported by Therapeutic Practice
with Fatigue educational grants from industry. The
Simon Aylwin, King’s Coll Hosp (UK) (Supported by Pfizer, Inc.)
Society ensures that all are in strict Program Director: To Be Announced
John Miell, Univ Hosp Lewisham (UK) compliance with ACCME and American
Endocrinopathies of Sickle Cell Disease Medical Association (AMA) guidelines. Thyroid Disease & Pregnancy
Guillermo Umpierrez, Emory Univ Sch of Med These continuing medical education (Supported by Abbott Laboratories)
activities have been planned and Program Director: To Be Announced
Ethical Dilemmas in Hormone implemented in accordance with the
Clinical Outcome of Hyponatremia
Replacement Therapy E Essential Areas and Policies of the ACCME.
(Supported by Otsuka America
Paul Komesaroff, Monash Univ (Australia) For Disclosure Policy and Policy on
Pharmaceutical, Inc.)
Unlabeled/Off-Label Usage, refer to
Flushing & Sweating Continuing Medical Education (CME) Program Director: To Be Announced
Pierre-Marc Bouloux, Royal Free Hosp (UK) Accreditation on page 25 of this program.
6:3 0 – 9:00 P M
Meet the Editor-In-Chief of The Journal This event is approved by the Canadian Minority Involvement Clinical
of Clinical Endocrinology & Metabolism Society of Endocrinology and Metabolism Research Symposium & Dinner
Paul Ladenson, John Hopkins Univ Sch of Med as an Accredited Group Learning Activity (Supported by the Robert Wood Johnson
MEN 1 (Section 1) as defined by the Maintenance Foundation)
Stephen Marx, NIDDK/NIH of Certification program of The Royal Program Director: Maria Alexander-
College of Physicians and Surgeons Bridges, MD
MEN 2 of Canada.
Robert Gagel, Univ of Texas MD Anderson 6:3 0 – 9:3 0 P M
Cancer Ctr Managing Multiple Cardiovascular
C M E S Ancillary Symposia
Programs are subject to change. Space is Risk Factors: Focus on Obesity,
Molecular Biology for the Clinician
Overweight & Type 2 Diabetes
John Kopchick, Ohio Univ/Edison Biotech Inst available on a first-come, first-served basis
(Supported by Sanofi-Aventis)
for registered physicians and allied health
Pearls from an Endocrine Surgeon Program Director: To Be Announced
professionals. There is no cost to attend.
Cord Sturgeon, Northwestern Univ Feinberg All programs will be held at the Fairmont Novel Targets for Diagnosis &
Sch of Med Royal York or the Westin Harbour Castle Treatment of Endocrine Neoplasia
Transsexualism: The Endocrinologist’s except for the CGM Workshop, which (Supported by The Endocrine Society
Role will be held at the Metro Toronto Corporate Liaison Board)
Thomas Murphy, Metrohealth Med Ctr Convention Centre. Program Director: Campbell P Howard, MD
(Cleveland, OH)
What To Do with the Patient with
Idiopathic Edema
John Monson, London Clin Ctr for Endo

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23
CLINICAL SCIENCE & PRACTICE SESSIONS ORAL & POSTER SESSIONS

Sunday, June 3 At ENDO 07, there will be approximately 50 five-speaker oral
Scientific Program
6:00 – 8:00 A M sessions during the four-day meeting. New this year, there will be
Growth Hormone Related Disorders: Molecular Genomics
& Clinical Implications four days of poster presentations. Sessions will be assembled from
(Supported by GATE Pharmaceuticals) the more than 2,600 abstracts received for consideration. The
Program Director: David R Brown, MD Annual Meeting Steering Committee reviews and schedules the
best abstracts in these sessions in early February. Check the
Stressing Glycemic Constancy: The New Paradigm in ENDO 07 Web site for the oral and poster session schedule.
Diabetes Care
(Supported by Eli Lilly & Company) Oral & Poster Session Categories
Program Director: Jerry Palmer, MD
Adipokines, Appetite & Obesity
Management of Metabolic Bone Disease in Patients with Adrenal Axis
Chronic Kidney Disease Aging
(Supported by Abbott Renal) Bone & Mineral Homeostasis
Program Director: Paul Miller, MD Cardiovascular Endocrinology
Case Reports
6:3 0 – 9:3 0 P M Diabetes & Glucose Metabolism
Incretin Agonists & DPP-IV Inhibitors: Novel Approaches Effects of Hormones on Cancer
in the Treatment of Type 2 Diabetes Endocrine Disruption
(Supported by Merck & Co., Inc.) Endocrine Genetics
Program Director: Bernard Zinman, MD, FACP, FRCP Endocrine Neoplasia & Tumors
Endocrine Nursing
Prolactinomas, Cushing’s & Acromegaly: An Update in Evolutionary & Developmental Endocrinology
Medical Therapy for Pituitary Adenomas Female Reproductive Endocrinology
(Supported by Novartis Pharmaceuticals) Fetal Placental Physiology
Program Director: Beverly Biller, MD Gene Expression
Co-Chair: Marco Boscaro, MD Growth Hormone & Prolactin Biology
Health Care Delivery
Aggressive Non-iodine Avid Thyroid Cancer Hormones & Immunity
(Supported by Amgen) Inhibins-Activins-TGF-Beta Superfamily
Program Director: Ernest Mazzaferri, MD Insulin-Like Growth Factors
Male Reproductive Endocrinology
Monday, June 4 Neuroendocrinology
6:00 – 8:00 A M Pediatric Endocrinology
Hyponatremia: State of the Art Clinical Pituitary
(Supported by Astellas Pharma US, Inc.) Signaling
Program Director: Gary Robertson, MD Steroid Superfamily: Hormones, Receptors & Actions
Thyroid
Treatment of Hypogonadism
(Supported by Indevus Pharmaceuticals, Inc.)
Program Director: To Be Announced
6:3 0 – 9:3 0 P M
Beyond Surgery: The Role of Medical Therapy in
Acromegaly
(Supported by Tercica, Inc.)
Program Director: Pamela Freda, MD
Medullary Thyroid Cancer

(Supported by AstraZeneca)
Program Director: Martin Jean Schlumberger, MD
Tuesday, June 5
6:00 – 8:00 A M
Changing Paradigms in the Treatment of Type 2
Diabetes: Results From Recent Pivotal Trials
(Supported by Takeda Pharmaceuticals North America, Inc.)
Program Director: Edward Horton, MD

www.endo-society.org/endo/development
24 B C T E
Continuing Medical
EDUCATION
Scientific Program
Accreditation The Endocrine Society has reviewed this activity’s speaker
The Endocrine Society is accredited by the Accreditation disclosures and resolved or managed all identified conflicts of
Council for Continuing Medical Education (ACCME) to provide interest, if applicable.
Continuing Medical Education (CME) for physicians.
Faculty disclosures will be printed in the ENDO 07 Program &
The Endocrine Society designates this educational activity for a Abstracts Book and in the Meeting & Exhibit Guide.
maximum of 37.0 AMA PRA Category 1 CreditsTM. Physicians
should only claim credit commensurate with the extent of their Policy on Unlabeled/ Off-Label Usage
participation in the activity. The Endocrine Society has determined that disclosure of unlabeled/
off-label or investigational use of commercial products is informative
Statement of Need for audiences and therefore requires that this information be dis-
Endocrinologists need a thorough knowledge of the most recent closed to the learners at the beginning of the presentation.
developments and techniques in endocrinology to ensure the
standard of patient care. Specific medicines discussed in this program may not yet be
approved and/or may not be specified to be used as indicated by
Learning Objectives the speaker. Before prescribing any medication, review the complete
Upon completion of this educational activity, participants should prescribing information, including indications, contradictions,
be able to: warnings, precautions, and adverse effects.
• Discuss state-of-the-art research in endocrinology
• Demonstrate updated knowledge of the diagnosis and Commercial Support
treatment of diabetes, osteoporosis, pediatric, thyroid and This activity is being supported by various commercial entities.
reproductive endocrine disorders The supporters will be acknowledged in the ENDO 07 Program &
• Employ enhanced skills and practice management techniques Abstracts Book and Meeting & Exhibit Guide. The Endocrine
to improve patient care Society gratefully acknowledges their generous support for this
educational activity.
Target Audience
The continuing medical education activity should be of The Endocrine Society takes responsibility for the content, quality,
substantial interest to: and scientific integrity of this CME activity. This activity has
been planned and implemented in accordance with the Essential
• Endocrinologists
Areas and Policies of the ACCME. The ENDO 07 scientific program
• Pediatric endocrinologists
was developed by the Annual Meeting Steering Committee prior
• Internists
to and independently of educational grant support. The commer-
• Clinical researchers
cial supporters of this meeting have no influence over topics or
• Other endocrine professionals
speakers. Educational grants support the overall meeting and are
not used to compensate speakers in supported sessions.
Disclosure Policy
As a provider of continuing medical education accredited by the
Accreditation Council for Continuing Medical Education
Getting Your C M E Credits or Certificate of
(ACCME), it is The Endocrine Society’s policy to ensure that the
Attendance
Registrants are to visit the designated CME and Evaluation stations
content and quality of this educational activity are balanced,
and complete their post-program evaluation form online. Once
independent, objective, and scientifically rigorous. All faculty
you have completed the evaluation, you may print your CME
participating in the CME activity are expected to disclose to the
Certificate and/or your Certificate of Attendance directly from
learners any significant financial interest or relevant financial
the computer in use. The ENDO 07 CME Certificate and
relationship(s) with the commercial supporters of the activity that
Evaluation service will also be available online after the meeting.
have occurred within the last 12 months. Such relationships may
include grants, research support or participation in industry-
This event is approved by the Canadian Society of Endocrinology
sponsored research, stock ownership, employment, consultation
and Metabolism as an Accredited Group Learning Activity
or participation in speakers bureaus and boards of directors. The
(Section 1) as defined by the Maintenance of Certification program
intent of this disclosure is not to prevent a speaker with significant
of The Royal College of Physicians and Surgeons of Canada.
financial or other relevant relationships from making a presentation
but rather to provide learners with information on which they
can maketheir own judgments. It remains for the learners to
determine whether the speaker’s interests or relationships may
influence the presentation with regard to exposition or conclusion.

www.endo-society.org/endo/cme/
25
Professional Development
OPPORTUNITIES
Fellow & Student Reception Career Development Workshops
Friday, June 1 Saturday, June 2 – Tuesday, June 5
6:00 – 7:30 PM The 9th Annual Career Development Workshop, developed
All fellows and students attending ENDO 07 are invited to this by the Trainee Development Committee, has evolved to further
popular event. Catch up with colleagues and friends, enjoy light meet the needs of trainees. Rather than a single event that
refreshments, and join The Endocrine Society in honoring all precedes ENDO, this year’s workshop will feature sessions on
ENDO travel grant recipients. Indicate your interest in attending career development topics scheduled throughout the entire meeting,
this reception by marking the appropriate box on the ENDO 07 with two or three sessions each day. Each session will target
Registration Form (see page 45). specific constituencies as well as provide networking and
Contact: Danielle Jordan at djordan@endo-society.org or professional development opportunities in an intimate environment.
301.951.2616. ENDO Registrants can attend any of the following sessions:
Career Opportunities in Industry: A panel discussion with

Job Fair industry speakers from each constituency (physician-in-practice,
Friday, June 1 clinical scientist, basic scientist) will discuss past work experiences
1:00 – 7:00 PM and how to succeed in industry.
Saturday, June 2 – Monday, June 4
7:30 AM – 6:30 PM Challenges for the International Trainee: This presentation
The Job Fair provides a special service to help employers fill vacant will address issues specific to endocrine trainees in a non-US-
positions and to help candidates find a new professional setting. based training program.
Employers: Fill a vacant position Ethics in Publishing: The information in this lecture will help
• Post an unlimited number of job descriptions at ENDO 07 you navigate the process of ethically publishing your endocrine
• Receive CVs of every candidate registered with the Job Fair research.
(over 100 expected)
• Post your job descriptions on The Endocrine Society Web site Interviewing Skills: This informative session will assist you in
• Interview candidates of your choice successfully interviewing for each advancement in your career.
(Employers not attending ENDO 07 can benefit from all of the Meet the Editors-in-Chief: Network with the Editors-in-Chief
above, except interviews.) of The Endocrine Society’s peer-reviewed journals.
Candidates: Find a new professional setting Meet the President & President-Elect: Network with
• Receive copies of all job descriptions posted at ENDO 07 Endocrine Society President Leonard Wartofsky and President-
• Post your CV on The Endocrine Society Web site Elect Margaret Shupnik.
• Attend on-site interviews.
(Candidates not attending ENDO 07 can benefit from all of the Meet the Trainee Development Committee: Find out what it
above except interviews.) takes to participate in Society leadership. Meet past, present, and
incoming members of the Trainee Development Committee,
which is comprised of and chaired by trainees.
Registration Fees (All rates in USD)
Employer Attending $400 Mock Study Section: A panel will go through the step-by-step
Employer Not Attending $340 process of study section.
Candidate In-Training $ 15
Setting Up a Lab: Learn the necessary skills to set up your first
Candidate Members $ 25 lab, including the unique challenges and common pitfalls to
Candidate Nonmember $ 50 avoid.
Contact: Colleen Gorman at cgorman@endo-society.org or
To register, visit www.endo-society.org/placementservices. On-site 301.951.2611.
registration will also be available.
Contact: Christine Whorton at placement@endo-society.org or
800.361.3906 or 520.544.2760.

26 www.endo-society.org/endo/development
All programs will be held in The Metro Toronto Convention Centre unless otherwise noted.
PROFESSIONAL DEVELOPMENT OPPORTUNITIES

Fellow & Student Lounge notes
Saturday, June 2 – Tuesday, June 5
8:00 AM – 6:00 PM
In addition to the Career Development Workshops Sessions,
trainees attending ENDO are encouraged to stop by the Fellow &
Student Lounge — created just for them. As the hub of activity
for endocrine trainees, the Fellow & Student Lounge will provide
you with the opportunity to network, learn, and just plain relax.
At least two programs per day will be scheduled in the lounge
and will include career development topics and networking
opportunities with the leaders in endocrinology.
Contact: Colleen Gorman at cgorman@endo-society.org or
301.951.2611.
Minority Mentoring Reception

Sunday, June 3
6:30 – 8:30 PM
Westin Harbor Castle
The Minority Affairs Committee is hosting the Minority
Mentoring Reception during ENDO 07, where advisors at topic
tables are available to address the career challenges facing minority
students, postdocs, fellows, and faculty. This event presents a
great networking opportunity for mentors from The Endocrine
Society, industry, and government to share their career experiences.
Its success very much depends on mentor support and participation.
You can register to become a mentor in spring 2007.
Contact: Kirsta Suggs at mac@endo-society.org or 301.941.0244.

www.endo-society.org/endo/development
27
Conference
EVENTS
Satellite Meetings Increasing Minority Involvement in
Friday, June 1
7:30 AM – 7:00 PM
Clinical Research Dinner
Saturday, June 2
Westin Harbour Castle
6:30 – 9:00 PM
5th Annual Meeting of the Androgen Excess Society (AES)
Fairmont Royal York
The Androgen Excess Society Annual Meeting is held in
conjunction with ENDO 07. The 2007 AES meeting format is A lively, wide-ranging, and informative panel-led discussion
designed to deliver cutting-edge research while serving as an on issues related to minority involvement in clinical research.
Speakers include Kenneth A Getz, Alfonso Alanis, MD, James R
international forum for physicians and scientists interested in
Gavin III, MD, PhD, representatives of funding/regulatory
disorders of androgen excess, such as polycystic ovary syndrome,
agencies, and members of the Society’s task force on eliminating
congenital adrenal hyperplasia, idiopathic hirsutism, and disparities in clinical trials.
premature adrenarche.
For registration, program information, and abstract submissions Corporate Liaison Board Forum
and deadlines, visit www.ae-society.org or contact Faye Byrd at Saturday, June 2
faye.byrd@cshs.org. Registration fees: AES Members $100; 6:30 – 9:30 PM
nonmembers $150. Fairmont Royal York
The Forum, hosted by the Corporate Liaison Board, will focus on
novel targets for diagnosis and treatment of endocrine neoplasia,
Exploring Strategies to Increase Minority with speakers from industry, academia, and government discussing
new technologies, biomarkers, and targeted molecular therapies.
Involvement in Clinical Research
Symposium Novel Targets for Diagnosis and Treatment of
Endocrine Neoplasia
(Supported by the Robert Wood Johnson Foundation)
Saturday, June 2 Introductory Remarks: Campbell P Howard, MD, Program Director
9:30 – 11:00 AM Therapeutic Utility of Somatostatin Analogs in Endocrine Neoplasia
Mounting evidence of ethnicity-specific differences in response Michael Culler, MS, PhD, Ipsen, Dept of Endo Research
to therapeutics, as well as expression of risk markers that inform Multiple Endocrine Neoplasia Type 1: Targeting the Humors &
treatment, demands that more be done to determine the scope Tumors
and basis of such differences. Achieving statistically powerful Stephen Marx, MD, Metabolic Dis Branch, NIDDK/NIH
subpopulation analysis requires that we eliminate disparities in Nuclear Hormone Receptors as Targeted Thereapy in
clinical trial participation. Best practices for increasing involvement Thyroid Cancer
of minority groups — developed by stakeholders in the community, Bryan Haugen, MD, Univ of Colorado Hlth Sci Ctr
academia, industry, and government — will be presented with a Contact: Nancy Chill at nchill@endo-society.org.
focus on increasing participation of minority physicians in
clinical research as an efficient means of reaching the minority
research volunteer.
Women in Endocrinology Dinner
Saturday, June 2
6:30 – 10:00 PM
This project began with a session during ENDO 06 in which Westin Harbour Castle
several speakers shared their experiences with recruitment in the More details to come; see the ENDO 07 Web site for updates and
academic and corporate settings. Speakers for ENDO 07 include more information. Contact Julie Sharpless for more information
Kenneth A Getz, MBA, chairman of CISCRP, and Dr Alfonso or special dietary requests at 919.966.1254 or
Alanis, CEO of Anaclim, who will discuss efforts to document julie_sharpless@cceb.med.upenn.edu.
and dispel impediments to participation of minority physicians
in clinical research. The Society’s recommendations will be
presented for subsequent discussion at the Clinical Research
Dinner to be held the same evening.

28 www.endo-society.org/endo/events/
CONFERENCE EVENTS
Endocrine Nurses Symposium 5th Annual Cardiovascular Endocrinology

(Supported by Genzyme Corporation)
Sunday, June 3
Dinner Symposium
Monday, June 4
7:00 AM – 5:00 PM
7:00 – 9:00 PM
Fairmont Royal York
7:00 – 8:00 AM
Cardiovascular Endocrinology: New Therapeutic
What Is Evidence-Based Endocrine Nursing Practice?
Approaches to Cardiovascular Disease Prevention
Margaret Eckert-Norton, MS, RN, CDE, State Univ of New York
(Supported by GlaxoSmithKline Pharmaceuticals, Inc.)
8:05 – 9:00 AM The Cardiovascular Endocrinology Dinner Symposium will be
Growth Hormone: Transition from Pediatrics to Adult hosted by Dr Ellen Seely and Dr Robert Carey. All ENDO 07
Peter Tebben, MD, Mayo Clin registrants with an interest in cardiovascular endocrinology are
encouraged to attend. To register, check the appropriate box on
9:05 – 10:00 AM the Registration Form (see page 45). Limited to 200 registrants;
The Diabetes Gap: The Translation of Benefits to the Patients registration fee $50 USD.
Jose F Caro, MD, Eli Lilly Res Labs (Indianapolis, IN)
10:30 AM – 12:00 PM Hormone Foundation 5K Run/Walk

Thyroid Grand Rounds (Title Sponsor 5K Run/Walk: Takeda Pharmaceuticals North
(Supported by Abbott Laboratories) America, Inc.; Presenting Sponsor: Abbott Laboratories)
David Cooper, MD, Sinai Hosp of Baltimore Sunday, June 3
Naomi Walpert, RN, Sinai Hosp of Baltimore 6:00 AM
Bryan Haugen, MD, Univ of Colorado Hlth Sci Ctr All ENDO 07 attendees, families, and friends are encouraged to
Beverly McLaughlin, RMA, Univ of Colorado Hosp come out for The Hormone Foundation’s fifth Annual 5K
Run/Walk. The Run/Walk will take you around the beautiful
1:35 – 2:30 PM Toronto waterfront. To register, complete the Registration Form
Hormone Abuse in Sports on page 50 or visit https://secure.hostdmc.com/endocrine/.
Alan Rogol, MD, PhD, Univ of Virginia
Established by The Endocrine Society in 1997, The Hormone
2:30 – 2:45 PM Foundation’s mission is to serve as a resource for the public by
Break promoting the prevention, treatment and cure of hormone-related
conditions through outreach and education. All proceeds will
2:50 – 3:45 PM benefit the Foundation.
Improved Diabetes Management: Only a Breath Away?
Jose Cara, MD, Pfizer Global Pharm (NY) Networking Breaks
Special networking breaks in the program will not only give
3:50 – 4:45 PM you the opportunity to relax, but also to interact with speakers,
Type 1 Diabetes: Transition from Adolescents to Adults introduce your trainees to colleagues, and catch up with old
Mark Sperling, MBBS, MD, FRACP, Children’s Hosp-Pittsburgh friends. We hope this format will give you a chance to enjoy a
more intimate setting within the larger meeting formats. Light
4:45 – 5:00 PM refreshments will be served.
Evaluation & Raffle
Closing Reception
Tuesday, June 5
6:30 – 8:00 PM
All attendees and their registered guests are invited for an
evening filled with dancing complemented by elegant hors d’oeu-
vres and cocktails. To register, check the appropriate box
on the Registration Form (see page 45).

29 www.endo-society.org/endo/events/
29
Registration,
HOTEL, TRAVEL
Registration, Hotel, Travel
REGISTRATION INFORMATION
Key Dates & Deadlines Registration Fees (all rates in U S D)
Early Registration April 7 Early Registration: April 7
Advance Registration May 11
Receipt of Cancellation to Receive Refund May 11 Member Nonmember Member Savings
Last Day to Apply for Membership to Professional $375 $780 $405
Receive Discounted Meeting Rates May 14 In-Training $190 $325 $135
On-site Registration Opens June 1
Emeritus $0 n/a n/a
ENS Nurse $375 $780 $405
Methods of Registration One Day Only $215 $275 $60
Early Registration: Register early and save 20%. In
Guest/Spouse $90 $90 n/a
addition, you will receive the ENDO 07 abstracts on CD-
ROM (Abstracts2ViewTM) prior to the meeting. Use any Advance Registration: May 11
of the following registration methods by April 7 to take
Member Nonmember Member Savings
advantage of this offer:
Professional $515 $990 $475
Mail: ENDO 2007 Registrar
c/o Laser Registration In-Training $275 $415 $140
1200 G Street, NW, Suite 800 Emeritus $0 n/a n/a
Washington, DC 20005-3967 ENS Nurse $515 $990 $475
Fax: 888.695.5498 (domestic) One Day Only $280 $335 $55
514.228.3202 (international) Guest/Spouse $90 $90 n/a
Web: www.one-stop-registration.com/endo/ Registration Categories

Advance Registration: Register by May 11 by using one Member Non Member
of the three registration methods listed above. Professional An Active Member, Affiliate Anyone who is not a member of
Associate, Healthcare Associate or The Endocrine Society and is
On-Site Registration: Metro Toronto Convention Research Associate of The not applying for membership.
Centre – Hall C Endocrine Society who has paid
2007 membership dues.
Friday, June 1 1:00 PM – 7:00 PM
Saturday, June 2 6:00 AM – 5:30 PM A Fellow/Student Associate of Anyone who is currently a fellow
In-Training
Sunday, June 3 6:00 AM – 5:30 PM The Endocrine Society who has or student, is not a member of
Monday, June 4 7:30 AM – 5:30 PM paid 2007 membership dues. The Endocrine Society, and is
Tuesday, June 5 7:30 AM – 5:30 PM not applying for membership.
Emeritus An Emeritus Member of The n/a

Payment Endocrine Society.
A completed Registration Form, along with full payment,
your credit card number, or check, must accompany your ENS Nurse A member in good standing of A nurse who is neither a member
The Endocrine Nurses Society. of The Endocrine Nurses Society
registration in order to be processed. Registrations nor The Endocrine Society.
without full payment will not be processed. If you are
faxing your reservation, do not mail, as you may be One Day Only Anyone from the categories listed Anyone from the categories
double charged. To confirm your faxed registration was above who will attend only one listed above who will attend
received, email ENDO@Laser-Registration.com. day of the meeting. Separate one- only one day of the meeting.
day registrations will not be Separate one-day registrations
accepted for multiple days. will not be accepted for
Only US currency will be accepted for registration multiple days.
payment on-site in Toronto.
Other
Guest/Spouse A nonscientific family member/guest of the registrant. Guest
registration provides admission to the guest breakfast, exhibits, poster
sessions and closing reception. Guest name must be included on the
registration form. Guests cannot attend sessions and are not eligible
for credits. Children under age 16 may not enter the Exhibit Hall.
Complimentary Those contacted and identified as “complimentary” by The

Endocrine Society.
Page content as of January 20, 2007 – for up-to-date information, visit www.endo-society.org/endo/registration
Discounted Registration Rates Letter of Invitation

Become A Member and Save If you require a letter of invitation to participate in ENDO 07,
Endocrine Society members save up to 60% on ENDO registration. check the appropriate box on the Registration Form (see page 45)
If you would like to become a member and receive the discounted and one will be forwarded to you with your confirmation
registration rates, be sure to do so before registering for ENDO 07. letter. Pre-registration is required.
To apply for or reinstate your membership, visit
www.endo-society.org/Join/. For Italian Registrants, contact the Italian Congress Agency
(as imposed by the Italian Health Ministry) using one of the
*The 60% savings applies to members who register for ENDO by following methods:
the early registration deadline (April 7) and does not include annual
membership dues. Mail: Maurizio Pieri
Direttore Convention & Congressi
Student/Fellow Member Discount Promoviaggi Spa
Register two in-training members and get the third registration V.le Gian Galeazzo, 3 – 20136 Milano
free (maximum of 4 free registrants). A Student/Fellow Group Italy
Registration Form is available at www.endo-society.org/endo. To
receive this discount, you will need to: Phone: 39 02 581891
• Register group by May 11
• Book hotel accommodations through the ENDO 07 Fax: 39 02 8373448
Housing Block
• Everyone in group must be from the same organization, Email: mpieri@promoviaggi.it
department, and city
• Provide group registration payment in one transaction Cancellations & Refunds
Requests for refunds must be received in writing by May 11.
Early Registration Discount No refunds will be issued for cancellations received after this date
Register early for ENDO 07 and save 20% on your registration. or for no-shows. All refunds will be processed after the Annual
To receive this discount, you will need to register for ENDO prior Meeting, minus a $50 USD administrative fee. Send requests for
to the April 7 deadline. refunds to:
Registration Extras Mail: ENDO 2007 Registrar

Direct Access to 160 Hours of ENDO Content new c/o Laser Registration
The ENDO 07 Session Library is a new product developed by 1200 G Street, NW, Suite 800
The Endocrine Society to provide access to ENDO 07 scientific Washington, DC 20005-3967
content on your personal computer. This state-of the-art product
will not only provide the session content that you missed at Fax: 888.695.5498 (domestic)
ENDO, but also will provide the science so critical in keeping 514.228.3202 (international)
your research cutting edge and your practice up-to-date.
• Review 160 hours of session material at your own pace Email: ENDO@Laser-Registration.com
• Available in both online and DVD-ROM formats
• Includes all participating plenary, symposia, debates, updates,
and other special sessions
• Opt to receive all session content or receive the Clinical
Track or Basic Track separately
Reserve your copy today at www.endo-society.org/endo. Offer
valid for ENDO 07 attendees.
Food Service – Grab-n-Go Lunches

Don’t waste time waiting in lines for lunch. Grab-n-Go lunches
are affordable, freshly made and will consist of either a sandwich,
snack, and beverage or a salad, snack, and beverage. The lunches
will be offered for $12 USD per day. To order, check the
appropriate box on the Registration Form (page 45).

www.endo-society.org/endo/registration/ 31
HOTEL INFORMATION
HOTEL INFORMATION
Hotel List & Rates

ALL RATES IN CANADIAN DOLLARS
Hotel Number of Single/ Shuttle Room Wi-Fi® HighSpeed Distance from

Number Hotel/Address Rooms Double Service Service Internet InternetAccess Convention Centre
1 Fairmont Royal York 1000 $260/$260 Y Y Lobby $13.95 0.3 mi/0.5 km

(Co-Headquarters)
100 Front Street West
2 Westin Harbour Castle 700 $263/$263 Y Y N $10.95 0.8 mi/1.4 km

(Co-Headquarters)
1 Harbour Square
3 Courtyard by Marriott 400 $175/$175 Y Y Y Free 1.7 mi/2.7 km

Downtown Toronto
475 Yonge Street
4 Delta Chelsea Hotel 350 $189/$189 Y Y N $11.95 1.4 mi/2.2 km

33 Gerrard Street $159/$159
(student)
5 Holiday Inn On King 250 $202/$202 Y Y N Free 0.6 mi/0.9 km

370 King Street West
6 Hilton Toronto 300 $247/$247 Y Y Lobby $12.95 0.6 mi/0.9 km

145 Richmond Street West
7 InterContinental 400 $279/$279 N Y Lobby $9.95 Connected

Toronto Centre $349/$349
225 Front Street West (club)
8 Renaissance Hotel Toronto 180 $233/$233 N Y Lobby $12.95 0.4 mi/0.6 km

Downtown
1 Blue Jays Way
9 Sheraton Centre Hotel 300 $253/$253 Y Y Lobby $14.95 0.9 mi/1.5 km

123 Queen Street West
s i n g B l ock – a r t e r H otels –
r o u g h the Hou fits: a t t h
u
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B o o k T R e a p t h e Bnevennetion center Boo k Eve
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Benefit tion cen
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s
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• Free s es available tion of a in walk nding
at nc entra • With ience in atte
• Best r king—high co en
N etw or • Conv
•

www.endo-society.org/endo/housing/
33
HOTEL INFORMATION
Key Dates & Deadlines Group Housing Reservations
Group Housing Request April 7 Group Housing reservations must be made through the ENDO
Housing Request May 4 2007 Registrar. Call 888.695.5481 or 202.347.6659 or email
ENDO@Laser-Registration.com and state that you are requesting
a group (10 or more registrants required). The Group Housing
E N D O 07 Housing Block
Request Form, deposit payment, and signed Group Housing
Reap the Benefits
Agreement must be received by the Housing Bureau prior to
Book your hotel reservation through the ENDO 07 Housing Block
April 7.
and reap the benefits. You will receive the best rates, free shuttle
service to/from convention center, and optimal networking
opportunities due to the high concentration of attendees staying Reservation Confirmation
within the block. You will receive an email, fax, or letter confirming your
accommodation within 15 days of receipt of complete reservations.
When you book at the Headquarter Hotels, you will benefit even Confirmations will not be given over the telephone. If you have
more because they are not only within walking distance to the submitted a Housing Request Form and registered for ENDO 07,
convention center, but also are convenient for attending CMES but have not received a confirmation within 15 days, email the
Ancillary Symposia, which are located within these hotels. Housing Bureau at ENDO@Laser-Registration.com.
Super Discounted Rates for Students Please do not call your hotel until after May 11, as processing
All rates are discounted through the ENDO 07 Housing Block, your reservations from the Housing Bureau into the Hotel System
but we have negotiated super discounted rates for students that will take a few days. If you have received a confirmation number
book within the Delta Chelsea Hotel. This not only provides an from the Housing Bureau, the hotel will honor your booking.
opportunity to save, but also opens the doors for four full days
of networking with your peers.
Methods of Housing Reservation

You must be registered for ENDO 07 to obtain housing. Complete
a Housing Request Form (see page 47) and return with credit card
information or full payment to the ENDO 2007 Registrar by May
4 using one of the following methods:
Mail: ENDO 2007 Registrar
c/o Laser Registration
1200 G Street, NW, Suite 800
Washington, DC 20005-3967
Fax: 888.695.5498 (domestic)

514.228.3202 (international)
Web: https://www.-stop-registration.com/endo/
Housing reservations will not be accepted by telephone. If you are

faxing your reservation, do not mail, as you may be double
charged. Housing Request Forms without a credit card guarantee
will not be processed. Conference rates cannot be guaranteed past Changes & Cancellations
the deadline date of May 4. All cancellations will be charged a fee of $25 USD. Cancellations
received within 72 hours of check-in will be charged one night’s
If you wish to extend your stay beyond June 5, we will attempt to room and tax. All changes and cancellations prior to May 11 must
secure a room for you at your choice of hotel; however, room be referred in writing to the ENDO 2007 Registrar – Housing
occupancy and conference rates may not be available. Bureau. Any changes after May 11 must be made directly with
the hotel.
34 Page content as of January 20, 2007 – for up-to-date information, visit

www.endo-society.org/endo/housing/
TRAVEL INFORMATION
Getting to Toronto ATC Online Travel Center

You’ll feel like a million miles away, but you’re not—Toronto’s The ATC Online Travel Center provides online booking tools
probably closer and easier to get to than you may think. and live agents to make your travel planning a cinch. You will
receive exclusive travel specials. You can book city tours and
Air: Toronto Pearson International Airport is Canada’s principal events online, including restaurants, theatrics, and concerts. To
airport, and ranks among the top 30 world airports. There are over start planning your trip, visit www.atcmeetings.com/endocrine.
76 scheduled and charter airlines currently serving the airport. Air
carriers provide nonstop service to 26 Canadian and 42 US The above discounts apply for travel May 30 – June 8, 2007.
(transborder) destinations and same-plane service to 56 other Some restrictions may apply. Service fees apply. ATC is available
International cities. for reservations from 9:00 AM – 7:30 PM EST, Monday – Friday.
Rail: VIA Rail and AMTRAK bring visitors into the heart of the Customs – Travel Made Easy
city each day. Toronto’s Union Station is located centrally We have assembled some of the frequently asked questions about
downtown, one block from the Metro Toronto Convention Centre travel to/from Canada and the resources you should rely on to
within easy walking distance from most ENDO 07 hotels. make your travel a snap.
Road: Several major highways link the surrounding cities to Do I need a passport and/or visa to travel to/from
Toronto. ENDO 07 is just a day’s drive from the following US cities: Canada?
Buffalo, Cleveland, Detroit, Pittsburgh, Rochester, and Syracuse.
US Citizens: Beginning January 23, 2007, the US government will
be requiring that each US citizen and permanent resident traveling
Discount Travel Reservations outside of the US by air must carry a valid US passport or other
Association Travel Concepts (ATC) is the official travel agency secure travel document such as a NEXUS Air card. All children,
for ENDO 07. ATC provides personalized service, advance seat regardless of age, must have their own passport to enter the US.
assignments, special meal requests, frequent flier program updates, Info: www.travel.state.gov/travel/cbpmc/cbpmc_2223.html
electronic ticketing, email access for convenient booking of your
tickets, and more. Non-US Citizens: Must carry a valid passport and visa. Citizens
from the United Kingdom, France, Germany, Mexico, Japan, the
Airline Discounts Republic of Korea, Australia, and others do not require a visa to
• Up to 15% off applicable classes of service for tickets purchased enter Canada. Contact a Canadian embassy, high commission, or
more than 30 days prior to the meeting. Restrictions apply consulate for information on what you will need before coming to
and not all classes of service receive the 15% discount Canada.
(United) Info: www.canadainternational.gc.ca/SBPage.aspx?pageid
• 5% off applicable classes of service for tickets purchased prior =665&lang=en#2
to the meeting (American Airlines)
• Multiple discounts available (Air Canada) What are the Canadian entry requirements for children?
• ATC will also search for the lowest available fare on any
airline If you are traveling with children under 18 years, you should carry
• You may also call your own agency or the vendors directly identification for each child, such as a birth certificate or green
and refer to the following ID numbers: card. Children traveling without their parents, with one parent,
United 510CK 800.521.4041 or with guardians should carry written permission. Divorced
American Airlines A2557AE 800.433.1790 parents with shared custody rights should carry legal documents
Air Canada 3EG3A7D1 800.361.7585 establishing their status.
Info: www.cbsa.gc.ca/E/pub/cp/rc4161/rc4161-e.html#P004
Car Discounts
• Avis & Enterprise What can delay or prohibit my entry into Canada?
• You may also call your own agency or the vendors directly You may not be permitted to enter Canada if you have a criminal
and refer to the following ID numbers: conviction, including a conviction for driving while impaired.
Enterprise 32H7476 800.593.0505 Info: www.cic.gc.ca/english/visit/inadmissibility.html
Avis J952801 800.331.1600
What are the US re-entry requirements for non-US citizens
Methods of Travel Reservation studying/working in the US?
Email: reservations@atcmeetings.com Make sure that your visa allows for multiple re-entries into the
US. If your return trip also involves a connection in the US, you
Fax: 858.362.3153 may need a visa for the trip to Toronto and another for the
return. Each stop may be counted as one entry and exit.
Web: www.atcmeetings.com/endocrine Info: www.cbp.gov/xp/cgov/travel/id_visa/

www.endo-society.org/endo/travel/ 35
TRAVEL INFORMATION
Where can US Citizens get a US passport? Hail a Taxi
First-time passport applicants need to apply for their passport in • Fares are standard, metered, and non-negotiable
person. Passport renewals can be done by mail if your most recent • The driver should start the meter at the beginning of your
passport is available to submit and is not damaged; you received ride and stop it when you reach your destination
the passport within the past 15 years; you were over age 16 when • Refuse to ride in a taxi without an operational meter
it was issued; you still have the same name, or can legally • If your service was acceptable, a 10% – 15% tip is customary
document your name change.
The Underground City
Info: http://travel.state.gov/passport/passport_1738.html PATH is Toronto’s underground walkway linking 27 kms (16
miles) of subterranean shopping, services, and entertainment.
Online Travel Resources Follow the brightly colored PATH signs and you’ll reach your
US Department of State: downtown destination easily in weatherproof comfort.
www.state.gov/travelandbusiness/ What to See & Do
Canada International: With Toronto’s bounty of theatres, attractions, museums, art
www.canadainternational.gc.ca/gtc/Going_To_Canada-en.aspx galleries, theme parks, markets, and even its very own islands,
there’s plenty of inspiration for your personal Toronto itinerary—
whether you like to preplan or discover as you go. Whatever you
Toronto Guide do, don’t forget to send postcards home. To search for more things
Toronto is an “intimate metropolis” with world-class dining, to see and do in Toronto, visit
shopping, innovation, architecture, and entertainment. From the www.mytorontomeeting.com/Visitor/WhatToSeeAndDo.
awe-inspiring CN Tower to the distinct, personality-rife
neighborhoods, Toronto caters to a vast array of interests, cultures,
and palates. Toronto Tours
To register for any of the Toronto Tours, complete the Tour
Sample a few of the more than 7,000 restaurants reflecting Registration Form on page 49.
cuisines from around the world or delight in shopping at the
trendy Queen Street West. Unwind as you traverse the lovely Daily Wake-Up Walks
waterfront or immerse yourself in a live theatre show. Venture Saturday, June 2 – Monday, June 4
outside of the city limits, and experience the wonder of Niagara 6:30 – 7:30 AM
Falls, a renowned wine region, and many intriguing outdoor
adventures. Complimentary
Join us each morning for a one-hour walking tour of Toronto’s
No matter what you choose to do during your visit, Toronto downtown. See sights such as the Financial District, Chinatown,
engages your imagination with an experience unlike any the or even the PATH. The PATH is downtown Toronto’s
world over. underground walkway linking 27 kilometers of shopping,
services, and entertainment.
Languages Spoken
There are two official Canadian languages—English and French.
Worlds within Toronto Neighborhood Tour, Including the
In addition to these, the top five languages spoken in Toronto are
CN Tower
Chinese, Italian, Tamil, Portuguese, and Spanish.
Saturday, June 2
Getting Around 9:00 AM – 1:00 PM
Public Transit Cost per participant: $55 CAD (+6% GST)
Explore Toronto on one of North America’s finest transportation Toronto is one of the most culturally diverse cities in the world.
systems—the Toronto Transit Commission (TTC)—as easy-to- Five ethnic communities (Chinese, Greek, Portuguese, Italian,
navigate subways, buses, and streetcars make getting around the Indian) all have cultural hubs spread throughout the downtown
city a snap. When using the TTC, a single fare will take you core. Toronto provides an ethnic flavor and variety that is simply
anywhere in the city on a one-way trip. You can freely transfer unmatched anywhere. In this tour, we explore three of the most
between subway, streetcar, and bus. popular communities: Chinatown on Spadina Street (including
Kensington Market), Greek Town on the Danforth, and Little
Driving Around Town Italy along College Street West. Next, we will travel to the CN
Toronto’s streets follow a basic grid pattern and are easy to navigate. Tower—the world’s tallest freestanding structure! We will take a
The city’s “rush hour” is more than an hour long—count on 58-second ride in a glass-faced elevator up the tower that will
heavy traffic from 7:00 – 9:00 AM and again from 4:00 – 6:00 PM. take you to the first of two lookout levels. Guests can also visit
the Observation Deck for spectacular views of the city, and, for a
unique view, guests can visit the Glass Floor, a mere 113 stories
(342 meters) above the streets below.

www.endo-society.org/endo/tourism.cfm
TRAVEL INFORMATION
Toronto Tours Continued walk through one of Toronto’s finest restored historic gardens that

features more than 300 varieties of plants in an original setting.
Toronto by Land & Sea: Harbour & City Tour
Saturday, June 2 Casa Loma: The final stop on this spectacular tour will be Casa
1:00 – 5:00 PM Loma. Sir Henry Mill Pellatt, the self-made millionaire, engaged
Cost per participant: $55 CAD (+6% GST) the noted architect E. J. Lennox to help him realize a lifelong
This activity-packed tour begins with a fully narrated harbour dream: the creation of a ‘medieval’ castle on the brow of a hill.
cruise on an elegant paddle boat. This entire vessel has been Intricately carved fireplaces, stately towers, beautiful windows,
refurbished with the perfect blend of varnished woods, wrought and exquisite doorways contribute to the complexity of Casa
iron, polished brass, and upholstery for your comfort. As the group Loma’s design. With its soaring battlements, sweeping grounds,
cruises among the natural beauty and serenity of the Toronto and secret passageways, it pays homage to the castles and knights
Islands, they will discover a preserved oasis. Sights from this of days gone by.
floating vantage point will include Toronto’s rebuilt harbour front,
the CN Tower, the Island Airport, Rogers Centre, and the stunning
Toronto Skyline. Once back on the ground, the group will embark
on an orientation tour of the city that will include all the
highlights of Toronto. They will explore the financial district,
the trendy fashion district, the world-class theatre district, and
some of Toronto’s many diverse cultural neighborhoods.
St Jacob’s Excursion (Lunch Included)

Sunday, June 3
9:00 AM – 5:00 PM
Cost per participant: $75 CAD (+6% GST)
Aquaint yourself with a gentler time in St Jacobs Country. You
will have the chance to discover the historic village and spend
some time shopping. Visit a variety of cultural exhibits – including Niagara Region Adventure (Lunch Included)
an abundance of fresh produce from across Ontario and from local Monday, June 4
farm gardens. Plus, you will find meats, cheese, baking, crafts, 9:00 AM – 5:00 PM
home decor, and a presentation on the history, culture, and reli-
gion of the Mennonite people. Step back in time and explore one Cost per participant: $99 CAD (+6% GST)
of Canada’s largest year-round farmers markets featuring furniture, Niagara Falls is a wondrous thundering spectacle of nature, with
clothes, tools, and more. Local delicacies such as summer sausage an astounding 35 million gallons of water rushing over 185 feet of
and pure maple syrup are sold by Mennonite farmers who travel sheer rock every minute, leaving guests breathless. The day begins
to market by horse and buggy. Indoors and outdoors, on the east with a scenic, 1-hour journey via motor coach to Niagara Falls.
and west side of Weber Street, you will find more than 600 vendors! Next, the power of Niagara Falls will be encountered up close on
For lunch, enjoy home-style comfort food in the warmth of the an exhilarating trip to the base of the Horseshoe Falls on the
Stone Crock Restaurant. Savoury roasted meats, hearty soups, salad historic “Maid of the Mist.” Afterward, lunch will be set atop the
bar, and famous fresh-baked pies and breads will delight your senses. Sheraton on the Falls in the Penthouse Dining Room. With a
beautiful view and only steps from the “Maid of the Mist,” you
Toronto Historic Homes Tour will enjoy a tasty buffet and the spectacular panorama while
Sunday, June 3 relaxing and resting your feet. After lunch, we will visit one of
1:00 – 5:00 PM Niagara’s local wineries, Peller Estates, for a tour, and taste some
of their award-winning wines. Finally, you will have the opportu-
Cost per participant: $56 CAD (+6% GST) nity to experience the charm and relaxed atmosphere of Niagara-
Mackenzie House: Start your “Historic House” tour at the on-the-Lake’s Olde Towne. Here you will have some free time to
incredible Mackenzie House. This is the restored family home of discover the first capital of Upper Canada, and one of the pretti-
William Lyon Mackenzie, leader of the famed 1837 Upper Canada est towns in Ontario. The day ends with a 1-hour motor coach
Rebellion and the first mayor of the City of Toronto. The late- trip back to Toronto.
Georgian townhouse is restored, as it would have appeared in the
twilight of Mackenzie’s years. The house features period rooms Worlds Within Toronto Including the CN Tower Tour
decorated to reflect middle-class city life in Toronto and boasts a
Monday, June 4
recreated print shop and exhibit gallery that tell the story of
1:00 – 5:00 PM
political upheaval in 1830s Toronto.
Cost per participant: $55 CAD (+6% GST)
Spadina Historic House: Spadina Historic House extends a warm See description for Saturday, June 2.
invitation to explore the elegant world of Toronto high society at
Toronto by Land & Sea: Harbour & City Tour
the turn-of-the-century (1900). Built by James Austin in 1866 on
an 80-acre estate, Spadina was home to four generations of one of Tuesday, June 5
Toronto’s leading families. Museum guides will introduce you to the 10:30 AM – 2:30 PM
life of the Austins, their children, and servants, as it evolved from Cost per participant: $55 CAD (+6% GST)
a Victorian country estate to an Edwardian city mansion. We also See description for Saturday, June 2.
Attendee
RESOURCES
Meeting Location Abstracts2View TM C D-R O M

ENDO 07 will be held at The Metro Toronto Convention Centre (Supported by GlaxoSmithKline Pharmaceuticals, Inc.)
(MTCC). The MTCC is located in the heart of vibrant All early registrants to ENDO 07 will receive an Abstracts2ViewTM
downtown Toronto. It’s within walking distance of the waterfront, CD-ROM in advance of the meeting. This CD-ROM is a
10,000 hotel rooms, and fine shopping, restaurants, and attrac- compilation of all abstracts presented at ENDO 07 and will help
tions. The city’s business, financial, fashion, and cultural districts you plan ahead to view the posters and oral presentations of interest
are minutes from its doorstep. Plus, it’s only a 20-minute drive to you. The CDs are operable on both Windows and Macintosh
from Pearson International Airport. computer platforms.
Metro Toronto Convention Centre
255 Front Street West
Meeting & Exhibit Guide
Toronto, Ontario The Meeting & Exhibit Guide will be distributed on-site only.
M5V 2W6 The printed book contains a complete listing of all exhibitors, as
well as the scientific program.
Parking & Maps
The MTCC has 1,700 indoor parking spaces. There are 10,000
E N D O 07 Session Library
more spaces within a one-kilometer distance operated by various With the ENDO 07 Session Library, you can review 160 hours of
parking companies. You can download maps of alternate parking cutting-edge ENDO 07 session content on your personal computer.
locations at www.mtccc.com/parkingandmaps/download.cfm. The product is available in both online and DVD-ROM formats
and will include all participating plenary, symposia, debates, updates,
North Building Parking (255 Front Street West): The entrance to and more. You can receive all session content, or you can order
the North Building parking garage is on Simcoe St just south of the Clinical Track or Basic Track separately.
Front St West. There are twelve disabled parking spaces located
on Level 4A of the garage. Reserve your copy today at www.endo-society.org/endo. Offer
valid for ENDO 07 attendees.
South Building Parking (222 Bremner Boulevard): The entrance
to the South Building parking garage is on Lower Simcoe St just Children’s Program
north of Lakeshore Blvd and just south of Bremner Blvd There KiddieCorp children’s program will be providing daycare services
are nine disabled parking spaces located near the glass doors June 2 – 5 at the Metro Toronto Convention Centre during
leading into the South building. ENDO 07. The program provides activities appropriate for each
age group (6 months – 12 years) and guarantees high staff-to-
Shuttle Bus Service child ratios (1:2 infants; 1:3 toddlers; 1:5 school age). KiddieCorp
Shuttle bus service will be provided between the Metro Toronto will supply snacks and beverages. Meals are the responsibility of
Convention Centre and all hotels within the ENDO 07 Housing the parent. KiddieCorp team members are selected according to
Block, except for InterContinental Toronto Centre and their integrity, experience, education, and enthusiasm. Plus,
Renaissance Hotel Toronto Downtown (both hotels are within they’re wonderful with kids. The KiddieCorp team is bonded and
walking distance of the convention centre). carries ample liability insurance.
Itinerary Planner To register, complete the registration and consent form on page
(Supported by Merck & Co., Inc.) 48 or register online at www.kiddiecorp.com/endokids.htm.
The Endocrine Society’s Abstracts2ViewTM online Itinerary KiddieCorp must receive both the Childcare Registration Form
Planner will help you maximize your time at ENDO 07. The and full payment to hold reservations. The advance registration
itinerary planner will be available in April. deadline is May 11. Register early, as on-site registrations are not
guaranteed. Space is limited on a first-come, first-served basis.
• Search the abstract database by author, topic, or date.
For more information, contact KiddieCorp at 858.455.1718 or
• Decide what sessions you want to attend.
endokids@kiddiecorp.com.
• Create your personal ENDO 07 calendar.
• Add sessions quickly and easily to your calendar.
• Save your calendar and make updates regularly.
Program & Abstracts Book

The Program & Abstracts Book contains all abstracts for the
ENDO 07 meeting. It is an important planning tool for attendees.
A printed book will be distributed on-site only.

www.endo-society.org/endo/attendees
EXHIBIT HALL
The ENDO 07 Exhibit Hall will be open Saturday, June 2 –
Exhibit Sales
Monday, June 4, 10:30 AM – 4:00 PM.
For more information on exhibiting at ENDO 07, contact
Exhibit Planner Darrin Scherago or Steve Hamburger using one of the
The exhibit planner is a Web-based, searchable system you can following methods:
use to build an itinerary of exhibits you would like to visit. The
planner will be available in April. Mail: Scherago International
• Search exhibitors by product category, city, state, or company 525 Washington Blvd, Ste. 3310
• Find an exhibitor’s exact location in the Exhibit Hall Jersey City, NJ 07310
• Create a personalized planner to take to the Exhibit Hall
• Click through to exhibitor Web sites for more information Phone: 201.653.4777
• Email exhibitors directly
Web: www.scherago.com/endo
Research Park
Research Park is a special section in the Exhibit Hall to make it
easy for researchers to find high-interest products and services.
This special section features a collection of 40+ research-based
exhibitors.
The Endocrine Society Booth

Stop by The Endocrine Society Booth and pick up your free
copies of The Journal of Endocrinology & Metabolism,
Endocrinology, Endocrine Reviews, and Molecular Endocrinology.
Also, get the new issue of Endocrine News. Find out about the
latest advocacy efforts. Become a member. Get your free patient
fact sheets. Find out about Society updates, products, services,
and more.
Communications Central
(Supported by Genentech, Inc.)
Located throughout the convention center, attendees will find
computer terminals for internet accessibility. Access to these
computers will be available only during official Exhibit Hall
hours. You must use the terminals provided; there will be no
facilities for connecting your personal laptop in this area.
Poster Sessions
ENDO 07 will feature poster sessions on all four days of the
meeting. Saturday – Monday, you will find a new set of posters
interspersed throughout the Exhibit Hall, representing the most
current scientific information in the field of endocrinology.
Tuesday’s poster presentations will be in Hall C. Presenters will be
available for two hours each day at 11:00 AM and 2:30 PM.
Relaxation Station
Stop by the relaxation station for a 10-minute massage. The
relaxation station will be centrally located on the exhibit floor
and is open to all meeting attendees at no cost.
Book Store
The Endocrine Society’s Book Store will feature stylish
“endocrine” apparel for all ages, toys for your little ones, gifts for
friends and family, and even a little something for your pet.

www.endo-society.org/endo/attendees 39
EXHIBIT HALL
2 007 Exhibitors
Abbott Diagnostics Merck & Co., Inc.

Abbott Laboratories Merck / Schering-Plough Pharmaceuticals
ALPCO Diagnostics Merck Human Health
ALZET Osmotic Pumps/Durect Corporation National Center for Biotechnology Information, NCBI
American Association of Clinical Endocrinologists National Kidney Foundation
American Peptide Company Nature Publishing Group
American Thyroid Association New Balance Athletic Shoe
Auxilium Pharmaceuticals, Inc. NIDDK
Bachem Novartis Pharmaceuticals
Beckman Coulter Perspective Enterprises Inc.
BioVendor Laboratory Medicine, Inc. Pfizer, Inc.
Blackwell Publishing Phoenix Pharmaceuticals, Inc.
Cambrex Research Products Purina Mills TestDiet
Cayman Chemical Company Qualigen, Inc.
Cell Signaling Technology Quest Diagnostics
Congressionally Directed Medical Research Programs R&D Systems, Inc.
CPC Scientific Inc. Research Diets, Inc.
Cushing Support & Research Foundation Review of Endocrinology
D2 Market Research Salimetrics LLC
Echo Medical Systems Smiths Medical
Eli Lilly & Company Solvay
Elsevier Canada Takeda Pharmaceuticals North America, Inc.
Endo Today/SLACK Incorporated TAP Pharmaceuticals
FASEB, MARC Program Tercica, Inc.
Freund Publishing House Ltd. The Endocrine Society
GATE Pharmaceuticals The North American Menopause Society
Genentech, Inc. ThyCa: Thyroid Cancer Survivors’ Association
Genzyme Tocris Bioscience
GlaxoSmithKline Pharmaceuticals, Inc. Universal Ultrasound
GlycoMark, Inc. Valera Pharmaceuticals, Inc.
Humana Press
Human Growth Foundation
Immuno – Biological Laboratories, Inc. (IBL-America)
Immunodiagnostic Systems, Inc.
Insmed Incorporated
Juvenile Diabetes Research Foundation
Karger Publishers
Keryx Biopharmaceuticals
King Pharmaceuticals
KRONUS, Inc.
MAGIC Foundation
Medtronic Diabetes

www.endo-society.org/attendees
Annual Meeting
CONTRIBUTORS
Annual Meeting Steering Committee
William F Young, Jr, MSc, MD, Chair Janet E Hall, MS, MD Renato Pasquali, MD
Mayo Clin Massachusetts Gen Hosp Univ Alma Mater (Italy)
Andrea C Gore, PhD, Basic Science Chair Marja M Hurley, MD Merrily F Poth, MD
Univ of Texas-Austin Univ of Connecticut Hlth Ctr Uniformed Svcs Univ of Hlth Scis
Peter J Trainer, MD, FRCP, Clinical Science Jens Jorgensen, MD, PhD Gail P Risbridger, PhD
& Practice Chair Aarhus Kommunehosp (Denmark) Monash Med Ctr (Australia)
Christie Hospital (UK)
W Lee Kraus, PhD Diane M Robins, PhD
Joseph T Bass, MD, PhD Cornell Univ Univ of Michigan Med Sch
Northwestern Univ
Benjamin Zev Leder, MD Delores M Shoback, MD
Daniel D Bikle, MD, PhD Massachusetts Gen Hosp Univ of California-San Francisco/
Univ of California-San Francisco/ VA Med Ctr
VA Med Ctr Ellis R Levin, MD
Long Beach VA Med Ctr Robert C Smallridge, MD
Louise M Bilezikjian, PhD Mayo Clin-Jacksonville
Salk Inst Jon E Levine, PhD
Northwestern Univ Doris A Stoffers, MD, PhD
Molly C Carr, MD Univ of Pennsylvania Sch of Med
Northwestern Univ Peter E Lobie, MD, PhD
Univ of Auckland (New Zealand) Larry J Suva, PhD
David R Clemmons, MD Univ of Arkansas for Med Sci
Univ of North Carolina Christos Mantzoros, MD
Beth Israel Deaconess Med Ctr Theo J Visser, PhD
John M Connell, MD, FRCP Erasmus Univ Med Ctr (Netherlands)
Univ of Glasgow (Scotland) Berenice B Mendonca, MD
Univ Sao Paulo Fac Med (Brazil) Wilmar Wiersinga, MD, PhD
Denise R Cooper, MS, PhD Univ of Amsterdam
JA Haley VA Hospital Walter L Miller, MD
Univ of California-San Francisco Robert S Zimmerman, MD
Samuel E Dagogo-Jack, MD, FRCP Cleveland Clin
Univ of Tennessee-Memphis Jeffrey N Miner, PhD
Ligand Pharmaceuticals
Kevin L Grove, PhD
Oregon Natl Primate Res Ctr Charles V Mobbs, PhD
Mt Sinai Sch of Med
The Endocrine Society Officers

Leonard Wartofsky, MD, MPH Andrew Stewart, MD Lynnette Kaye Nieman, MD
President Secretary-Treasurer-Elect Vice President – Clinical Science
Margaret A Shupnik, PhD Andrea Elizabeth Dunaif, MD Henry M Kronenberg, MD
President-Elect Past President Vice President – Basic Science
Hershel Raff, PhD Carolyn Becker, MD
Secretary-Treasurer Vice President – Physician-in-Practice

www.endo-society.org/endo/contributors
41
Annual Meeting Contributors

2 007 Supporters (as of January 10, 2007)
The Endocrine Society would like to thank the following companies
for supporting ENDO 07. Their support enables the Society to provide
a relevant and superior program for all participants.
Abbott Diagnostics
Abbott Laboratories
Abbott Renal
Altus Pharmaceuticals
Amgen
Astellas Pharma US, Inc.
AstraZeneca
Berlex Laboratories
Eli Lilly & Company
GATE Pharmaceuticals
Genentech, Inc.
Genzyme Corporation
GlaxoSmithKline Pharmaceuticals, Inc.
Indevus Pharmaceuticals, Inc.
Medtronic Minimed, Inc.
Merck & Co., Inc.
Novartis Pharmaceuticals
Novo Nordisk Inc.
Otsuka America Pharmaceutical, Inc.
Pfizer, Inc.
Quest Diagnostics
Sanofi-Aventis
Solvay
Takeda Pharmaceuticals
North America, Inc.
Tercica, Inc.

www.endo-society.org/endo/contributors
Contact
INFORMATION
The Endocrine Society Registration & Housing Travel
Mail: 8401 Connecticut Ave., Suite 900 Mail: ENDO 2007 Registrar Email: reservations@atcmeetings.com
Chevy Chase, MD 20815 c/o Laser Registration
1200 G Street, NW, Suite 800 Fax: 858.362.3153
Phone: 888.363.6274 or 301.941.0200 Washington, DC 20005-3967
(main) Web: www.atcmeetings.com/endocrine
888.363.6762 or 301.941.0210 Phone: 888.695.5481 (toll free)
(Society Services) 202.347.6659 (main)
301.941.0220 (Meetings Services)
301.941.0231 (Membership) Fax: 888.695.5498 (domestic)
514.228.3202 (international)
Fax: 301.941.0259 (main)
301.941.0257 (Society Services) Email: ENDO@Laser-Registration.com
301.941.0259 (Membership)
Web: https://www.one-stop-
Web: www.endo-society.org (main) registration.com/endo
www.endo-society.org/endo
(ENDO 07)
JOB FAIR ENDO 07

June 1 - June 4, 2007 / Toronto, Ontario
Metro Toronto Convention Centre / Room 808
EMPLOYERS
• Postjobs in the online Employment
Opportunities Database
• Receive CV’s from all registered candidates
• Conduct interviews on-site
Participate. CANDIDATES
• Post your CV in the online CV Database
• Receive job descriptions from all registered
employers
• Participate in interviews on-site
Attendance at ENDO 07 is not required.
For more information, visit

www.endo-society.org/placementservices
or call 800.361.3906
Never miss another

ENDO Session.
I n t ro d u c i n g t h e E N D O 0 7 S e s s i o n L i b ra r y .
With the ENDO 07 Session Library, you can

review 160-hours of cutting-edge ENDO
07 session content on your personal
computer. The product is available
in both online and DVD-ROM
formats and will include
all participating plenary,
symposia, debates, updates
and more. You can receive
all session content or you
ar y can order the Clinical Track
Libr
s s i o n u rs o f or Basic Track separately.
0 Se
7 ss to 16 0 content. - ho
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E N D Direct ac0c7 scientifi
e c
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END
Reserve your copy today and save up to

*This special offer is available to
45%* at www.endo-society.org/endo. ENDO 07 attendees that register
for the meeting by May 11.
ENDO 07 REGISTRATION FORM F7CL
EARLY REGISTRATION DEADLINE: APRIL 7, 2007 • ADVANCE REGISTRATION DEADLINE: MAY 11, 2007
A. REGISTRATION INFORMATION (PLEASE PRINT ALL INFORMATION)
Prefix
° Dr. ° Mr. ° Ms. ° Prof.
LAST NAME FIRST NAME MIDDLE INITIAL
Check applicable degrees:
° MD ° PhD ° MD, PhD
° RN Ê° DO ÊÊ° RPh COMPANY/INSTITUTION
° Other:_____________
Which of the following best
describes your primary & DEPARTMENT/DIVISION
secondary professional role?
(“1” for primary; “2” for secondary)
_____ Administrator MAILING ADDRESS STREET
-
_____ Basic Researcher
_____ Clinical Researcher
_____ Clinical Practitioner CITY STATE COUNTRY ZIP/POSTAL CODE
_____ Fellow, Clinical
_____ Fellow, Postdoc/Research
_____ Industry/Corporate TELEPHONE (DAY): COUNTRY CODE/CITY CODE/NUMBER FAX: COUNTRY CODE/CITY CODE/NUMBER
_____ Nurse/Healthcare
_____ Retired
_____ Student E-MAIL
_____ Teacher/Educator
ALL INFORMATION IN SECTION A MUST BE COMPLETED IN ORDER TO REGISTER. IF INFORMATION IS NOT APPLICABLE PLEASE INDICATE N/A IN THE SPACE PROVIDED.
_____ Other
B. REGISTRATION CATEGORIES & FEES F. SPECIAL ACTIVITIES REGISTRATION

RECEIVED RECEIVED
ALL FEES ARE IN US DOLLARS BY AFTER Indicate which free activities you would like to attend.
APRIL 7 APRIL 7
14 °Ê Fellow and Student Reception, Fri June 1
MEMBER 15 °Ê Endocrine Nurses Society (ENS) Poster Session & Recptn, Sat June 2
1 °ÊÊProfessional $375 $515 ________ 16 °Ê Endocrine Nurses Society (ENS) Symp, Bus Mtg, Lunch, Sun June 3
2 °ÊÊIn Training $190 $275 ________ 17 °Ê Minority Mentoring Reception, Sun June 3
3 °ÊÊEmeritus Member $0 $0 ________ 18 °Ê Closing Reception, Tues June 5
4 °ÊÊENS Nurse $375 $515 ________
8 °ÊÊOne Day Only (PLEASE SELECT ONE) $215 $280 ________ G. MEET THE PROFESSOR HANDOUT BOOK
SPECIFY DAY ÊÊÊ°ÊSAT °ÊSUN °ÊMON °ÊTUES
19 °ÊÊI would like to receive a “Meet the Professor” Book onsite.
°ÊÊ I recently applied for membershipÊ
NON-MEMBER H. ADDITIONAL INFORMATION
5 °ÊÊProfessional $780 $990 ________ ° I will require special assistance. (Attach description of needs)
6 °ÊÊIn Training $325 $415 ________ ° I am traveling from outside the U.S. or Canada and will
7 °ÊÊNurse $780 $990 ________ require a Letter of Invitation for travel and visa processing.
9 °ÊÊOne Day Only (PLEASE SELECT ONE) $275 $335 ________ Provide passport #:__________________ (required)
SPECIFY DAY ÊÊÊ°ÊSAT °ÊSUN °ÊMON °ÊTUES ° Provide my email address to exhibitors.
OTHER ° Emergency contact (required):
10 °ÊÊComplimentary $0 $0 ________
11 °ÊÊGuest/Spouse $90 $90 ________ NAME
GUEST LAST NAME GUEST FIRST NAME DAY TELEPHONE EVENING TELEPHONE
TOTAL SECTION B: $ ________
C. EVENT & WORKSHOP FEES I. CANCELLATION POLICY
1 Thyroid Sonography Hands-on Wkshop, Fri June 1 (limited to first 65 registrants) Cancellations must be made in writing by May 11, 2007. See
°ÊÊMember and ENDO attendee $350 ________ registration instruction pages for the complete cancellation policy.
°ÊÊNon-Member and ENDO attendee Ê Ê $400 ________ J. METHOD OF PAYMENT
°ÊÊFellow/Student and ENDO attendee $250 ________
2 Women in Endocrinology Dinner, Sat June 2 Full payment must accompany your registration form. Enclose your check
°ÊÊAll attendees $65 ________ (payable to The Endocrine Society in U.S. funds only), or complete the credit
3 Cardiovascular Endocrinology Dinner, Mon June 4 card information below. American Express and purchase orders are not
°ÊÊAll attendees $50 ________ accepted as payment for registration fees.
20ÊABIM Self-Evaluation Process, Fri June 1 ° Check ° Money Order ° VISA ° MasterCard
(Add’l fee req’d. Details at http://www.endo-society.org/endo)
°ÊÊMember $100 ________
° Non-Member $150 ________ CARD NUMBER EXPIRATION DATE
°ÊÊIn Training Member/Non-Member $50 ________
TOTAL SECTION C: $ ________ NAME OF CARDHOLDER (PLEASE PRINT)
D. OPTIONAL FEES
"Grab-n-Go” Lunches - $12 per day ________ BILLING ADDRESS
4 °ÊÊSAT 5 °ÊSUN 6 °ÊMON 7 °ÊTUES (SELECT DAYS)
ENDO 07 Session Library – ENDO Attendees only (Select both format and program) SIGNATURE
FORMAT: °ÊÊ12 Month Online Access or °ÊDVD-ROM YOUR SIGNATURE AUTHORIZES YOUR CREDIT CARD TO BE CHARGED FOR THE TOTAL PAYMENT ABOVE.
THE ENDOCRINE SOCIETY RESERVES THE RIGHT TO CHARGE THE CORRECT AMOUNT IF DIFFERENT FROM
Complete Clinical Basic THE TOTAL PAYMENT LISTED ABOVE.
MEMBER Program Program Program
Professional °Ê$110 °Ê$70 °Ê$70 ________
In Training/Emeritus °Ê$80 °Ê$50 °Ê$50 ________
NON-MEMBER OR FAX REGISTRATION FORM
Professional °Ê$150 °Ê$100 °Ê$100 ________ with credit card information no later than May 11, 2007 to
In Training °Ê$120 °Ê$70 °Ê$70 ________ 888.695.5498 or Int'l fax 514.228.3202.
TOTAL SECTION D: $ ________ If faxing, do not mail or you will be double-charged.
E.E.PAYMENT
PAYMENTDUE
DUE TOTAL (B + C + D): $ ________ OR MAIL REGISTRATION FORM
with full payment no later than May 11, 2007 to:
ENDO 2007 Registrar
c/o Laser Registration
REGISTER ONLINE with credit card information at
1200 G Street, NW, Suite 800
www.one-stop-registration.com/endo/
Washington, DC 20005-3967
45
CEU 2007
Leading edge updates, advancements and
review on important topics in Endocrinology.
Thyroid / Pituitary / Bone & Mineral / Reproduction
Diabetes / Lipids & Cardiovascular / Adrenal & Hypertension
Additional programs:
Board Review
SEPTEMBER 25-26
American Board The most important

of Internal Medicine four days for your practice
Self-Evaluation Process September 27-30, 2007

SEPTEMBER 26 { San Antonio, Texas }
Thyroid Sonography
Hands-On Workshop
SEPTEMBER 30
REGISTER EARLY
for a chance to win one night free.
To be entered to win the free night’s stay, register before August 17, 2007.
Visit www.endo-society.org/education/events/ceu for information and registration.
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47
ENDO 07 CHILDCARE REGISTRATION FORM

June 2-5 2007 — Metro Toronto Convention Centre CONSENT FORM
Advance registration deadline: May 4, 2007. PARENT INFO Child(ren)’s first and last names:
NAME____________________________________AGE___________
PARENT INFO
LAST NAME ___________________________________ FIRST NAME ___________________________ NAME____________________________________AGE___________
NAME____________________________________AGE___________
PHONE (W) ______________________________
Please list ONLY those allowed to check-out the above
CHILD INFO child(ren) from the KiddieCorp Children’s program. (Please
list first and last names; photo ID may be required when
LAST NAME ___________________________________ FIRST NAME ___________________________
checking out children):
Each child must be registered for a minimum of two consecutive hours per child, per day.
NAME___________________________________________________
Hours Needed Total
Name(s) Age(s) (2 hour min.) # of hours RELATIONSHIP TO CHILD(REN)_____________________________
Saturday, June 2 1___________________ __________ __________ __________ NAME___________________________________________________

7:30 am - 6:30 pm 2___________________ __________ __________ __________ RELATIONSHIP TO CHILD(REN)_____________________________
3___________________ __________ __________ __________ Are any of your children allergic to anything (foods, etc.) or
are any of your children taking medication? If yes, explain.
(Note: KiddieCorp staff does not administer or assist in the
Sunday, June 3 1___________________ __________ __________ __________ administration of any medications.)
7:30 am - 6:30 pm
2___________________ __________ __________ __________ _________________________________________________________
_________________________________________________________
3___________________ __________ __________ __________
Do any of your children have health limitations or special
needs? Any birthmarks or injuries we should be aware of?
Monday, June 4 1___________________ __________ __________ __________
_________________________________________________________
7:30 am - 6:30 pm
2___________________ __________ __________ __________ _________________________________________________________
We, the undersigned adults, agree to place our child or ward

3___________________ __________ __________ __________
in the KiddieCorp children’s program. For ourselves, our
child/ward (or children/wards), and each of our respective
Tuesday, June 5 1___________________ __________ __________ __________ heirs, assigns and next of kin, we hereby release and agree
7:30 am - 6:30 pm to indemnify and hold harmless KiddieCorp, The Endocrine
2___________________ __________ __________ __________ Society, and their respective officers, directors, agents,
employees, assigns, vendors, and the owners and/or lessors
METHOD OF PAYMENT of the facility or facilities where the program will be held
Payment in full is required to confirm your reservations. Payment in US Dollars only. (collectively “the Releasees”) from any and all claims which
may now or hereafter arise from our child’s/ward’s (or
Although every effort will be made to accommodate late or on-site registrations, there is no
children’s/wards’) participation in the KiddieCorp program.
guarantee that KiddieCorp can accept children unless they are pre-registered. We do not release claims arising from Releasees from any of
their willful misconduct or gross negligence.
$6.00 per hour per child x _____ (# of Children) x ____ (# of Hours) = $________
We have read the above and understand this release.
(On-site Registration fee will be $7.00 per hour per child)
Furthermore, in the event of an emergency or health concern,
T Check (payable to KiddieCorp) T VISA T MasterCard T AMEX KiddieCorp has our permission to administer first aid, contact
our pediatrician, or obtain emergency medical treatment for
our child. We agree to pay all expenses incurred due to an
CARD NUMBER EXPIRATION DATE emergency involving our child.
PARENT/GUARDIAN NAME________________________________
BILLING ADDRESS
SIGNATURE _______________________________DATE__________
NAME OF CARDHOLDER (PLEASE PRINT)

ADDRESS ________________________________________________
SIGNATURE CITY/STATE/ZIP ___________________________________________

YOUR SIGNATURE AUTHORIZES YOUR CREDIT CARD TO BE CHARGED FOR THE TOTAL PAYMENT ABOVE. KIDDIECORP RESERVES THE RIGHT
TO CHARGE THE CORRECT AMOUNT IF DIFFERENT FROM THE TOTAL PAYMENT LISTED ABOVE. PHONE (H)____________________(W) _______________________
ADDITIONAL INFORMATION CELL/PAGER _____________________________________________

• KiddieCorp staff does not administer medication. To ensure a safe and fun-filled environment, any child
EMAIL___________________________________________________
who is ill will not be admitted to the children’s program.
• Please label your child’s belongings. We will maintain a lost and found, however, KiddieCorp does not HOTEL___________________________ROOM # _______________
accept responsibility for the loss or theft of any toy, book, or other personal items.
• For parents with infants, please bring diaper changing supplies, formula/baby food, and a change of clothes. PEDIATRICIAN’S NAME ___________________________________
CANCELLATION POLICY CITY ____________________________________________________

Cancellations must be made to KiddieCorp prior to May 26, 2007 for a full refund. Cancellations made after
EMERGENCY CONTACT ___________________________________
that date will be subject to a 50% cancellation fee. Once the program has begun, no refunds will be issued.
PHONE __________________________________________________
REGISTER ONLINE FAX REGISTRATION MAIL REGISTRATION We suggest you make a copy of your completed
with credit card by May 4, 2007 to with full payment by form as a reference. Confirmations will not be sent.
information at 1-858-455-5841. May 4, 2007 to: KiddieCorp reserves the right to limit participation of any
www.kiddiecorp. Credit Card Payments KiddieCorp/ENDO 2007 child whose presence or behavior may disrupt the program or
endanger the health or safety of others.
com/endokids.htm Only 10455 Sorrento Valley Road,
Suite 103
San Diego, CA 92121
48
ENDO 07 TOUR REGISTRATION FORM

RESERVATION DEADLINE: MAY 1, 2007
ACTIVITY TICKETS
NAME Activity confirmation/tickets will be picked
up at The Endocrine Society’s Tour
ADDRESS
Registration Desk at the Metro Toronto
CITY/STATE/ZIP Convention Centre. Each guest must have
their tickets to board the tour bus.
EMAIL FAX
DAYTIME PHONE EVENING PHONE

SPECIAL NEEDS
ALL COSTS ARE IN CAD AND DO NOT INCLUDE 6% GST
If you have a disability that may influence
your participation in the Tour Program, please
TOUR TOUR# TICKET $ #OF TICKETS SUBTOTAL 6%GST TOTAL $
attach a written description of your disability
Saturday, June 2
to your registration form. We cannot assure
T Wake-Up Walk (complimentary) #SA1 $0
availability of appropriate accommodations
6:30 - 7:30 AM
without prior notification of need.
TWorld’s Within Toronto Neigh- #SA2 $55
borhood Tour with CN Tower
9:00 AM - 1:00 PM
TERMS AND CONDITIONS
TToronto By Land and Sea: #SA3 $55 All tours will depart from the South
Harbour and City Tour
Entrance of the Metro Toronto Convention
1:00 - 5:00 PM
Centre. The South Entrance of the Metro
Sunday, June 3
Toronto Convention Centre is located on
TWake-Up Walk (complimentary) #SU1 $0 Bremner Blvd. just west of York St. Full
6:30 - 7:30 AM
payment must be received to confirm your
TSt. Jacob’s Excursion #SU2 $75 reservation. Reservations are confirmed
9:00 AM - 5:00 PM (lunch included)
on a first-come, first-served basis. Tour
TToronto Historic Homes Tour #SU3 $56 operator reserves the right to cancel any
1:00 PM - 5:00 PM
tour that does not meet minimum number
Monday, June 4 of participants. If tour is cancelled, full
TWake-Up Walk (complimentary) #M1 $0 refunds will be returned. Please print
6:30 - 7:30 AM clearly. All registrations must be received
TWorld’s Within Toronto Neigh- #M2 $55 no later than May 1, 2007.
borhood Tour with CN Towe
1:00 PM - 5:00 PM
TNiagara Region Adventure #M3 $99
9:00 AM - 5:00 PM (lunch included)
Tuesday, June 5
TToronto By Land & Sea: #T1 $55 QUESTIONS
Harbour and City Tour Contact Kyle Tomlin at 905-564-9911
10:30 AM - 2:30 PM or email kyle@hostdmc.com
TOTAL $
METHOD OF PAYMENT FAX REGISTRATION FORM

TCheck Enclosed Make check payable to HOST Destination Management (in Canadian funds) with credit card information
TVisa TMastercard TAmerican Express no later than May 1, 2007 to
Attn: Kyle Tomlin 905-564-5959.
CREDIT CARD AUTHORIZATION:
If faxing, do not mail or you will be
double-charged.
CARD NUMBER EXPIRATION DATE
OR MAIL REGISTRATION FORM
with full payment no later than
PRINT NAME ON CARD
May 1, 2007 to:
HOST Canada
AUTHORIZED SIGNATURE DATE
6999 Ordan Drive
WAIVER AND CONSENT
Mississauga, ON L5T 1K6
CANADA
LIABILITY WAIVER DISCLAIMER: I agree and acknowledge that I am undertaking such participation in ENDO 2007 Tour Event
and Activities as my own free and intentional act and I am fully aware that possible physical injury may occur as a result in my Attn: Kyle Tomlin
participation of these events. I give my acknowledgement freely and knowingly and that I am as a result, able to participate in
ENDO 2007 Tour events, and I do hereby assume responsibility for my own well being. I also agree not to allow any other individual Unfortunately, reservations cannot be made by
to participate in my place without alerting them to the above. This will be my responsibility.
telephone.
SIGNATURE DATE
49
ENDO 07 5K RUN/WALK REGISTRATION FORM

Sunday, June 3, 2007
Benefiting The Hormone Foundation
A
ll ENDO attendees, families and
EACH RUNNER MUST COMPLETE A SEPARATE FORM IN ORDER TO PARTICIPATE.
friends are encouraged to come
Each participant must complete and sign the registration and release form in order to participate. out for the 5th annual 5K Run/Walk
If additional forms are needed, feel free to make photocopies. Please print clearly. benefiting The Hormone Foundation.
The 5K Run/Walk will take you around
NAME COMPANY NAME
the beautiful Toronto waterfront.
BILLING ADDRESS
Established by The Endocrine Society
CITY/STATE OR PROVINCE ZIP/COUNTRY

in 1997, The Hormone Foundation’s
mission is to serve as a resource for the
PREFERRED EMAIL DAYTIME PHONE FAX
public by promoting the prevention,
AGE GENDER SHIRT SIZE

treatment and cure of hormone-related
T COMPANY HAS MATCHING GIFT PROGRAM conditions through public outreach and
education. All proceeds from the 5K
METHOD OF PAYMENT $20.00 USD per participant
Run/Walk will benefit the Foundation.
T Check enclosed Make payable to HOST Destination Management
T Visa T MasterCard T American Express
CREDIT CARD # EXP DATE
PRINT NAME ON CARD TITLE SPONSOR
Improving Health
BILLING ADDRESS Through Education
AUTHORIZED SIGNATURE DATE
PRESENTING SPONSOR
FAX REGISTRATION FORM
with credit card information no later than May 1, 2007 to 905.564.5959.
If faxing, do not mail or you will be double charged.
ADDITIONAL INFORMATION
MAIL REGISTRATION FORM
with full payment no later than May 1, 2007 to: Depart:
HOST Destination Management 5:30 AM Motorcoaches depart from
6999 Ordan Drive Metro Toronto Convention Centre
Mississauga, ON L5T 1K6 CANADA Race Starts:
Attn: Kyle Tomlin 6:00 AM sharp
Note: Registrations will not be accepted by telephone. Distance:
5K (3.1 Miles) certified
QUESTIONS? Email: kyle@hostdmc.com Race Location:
WAIVER AND RELEASE Toronto Waterfront
I UNDERSTAND AND ACKNOWLEDGE THAT THERE MAY BE INHERENT RISKS TO MY HEALTH OR OTHERWISE Weather: Rain or shine
INVOLVED IN PARTICIPATION IN THE ENDO 07 5K RUN/WALK AND I FREELY ASSUME THESE RISKS. I HEREBY CERTIFY Registration Fee:
THAT I AM IN GOOD HEALTH AND PHYSICAL CONDITION AND AM ABLE TO SAFELY COMPETE IN THE ENDO 07 5K
RUN/WALK. Advance: $20.00 USD per participant
I hereby agree to fully release, hold harmless and indemnify The Endocrine Society, HOST Destination
On-site: $25.00 USD per participant
Management, all government and municipal agencies whose property and/or personnel are involved, Race Numbers:
and all other co-sponsoring company or individuals and each of their respective owners, agents, affiliates, Distributed at the race site
subsidiaries, related entities, directors, officers, shareholders and employees from any responsibility,
liability or obligation for any loss(es), injury(ies), property damage(s), death(s)or other damage(s) I may
suffer or cause as a result of or related in any way to my participation in the ENDO 07 5K Run/Walk on FOR MORE DETAILS
Sunday, June 3, 2007.
Visit www.endo-society.org/endo
I HEREBY CERTIFY THAT I HAVE READ THE ENTRY INFORMATION PROVIDED FOR THE ENDO 07 5K RUN/WALK AND or The Hormone Foundation
THIS WAIVER AND RELEASE, FULLY UNDERSTAND THEM, AND CERTIFY MY AGREEMENT TO COMPLY WITH AND
ACCEPT THE TERMS THEREOF BY PLACEMENT OF MY SIGNATURE WHERE PROVIDED BELOW. at www.hormone.org or
call 1-800-HORMONE
PRINTED NAME SIGNATURE
SIGNATURE OF PARENT OR GUARDIAN (IF UNDER 18) DATE

50
Endo2007_KCC COVER 2/22/07 10:55 AM Page 3
Endo2007_KCC COVER 2/22/07 10:56 AM Page 4

Endo Final

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Endo2007_KCC COVER 2/16/07 3:04 PM Page 1

THE ENDOCRINE SOCIETY’S 89th Annual Meeting

FINAL REGISTRATION & PROGRAM INFORMATION

ENDO 07 is designed to deliver the networking of smaller meeting formats while

16 plenary lectures, 77 symposia, 180 Meet-the-Professor sessions and greater networking

one of the most diverse, modern and accessible cities in the

world. Don’t miss out on this huge opportunity to save.

To register now or for more information about ENDO 07,

AN OPPORTUNITY THIS GOOD

Meet the Chairs of the TABLE OF CONTENTS

“From my earliest days as an ENDO attendee, the Scientific Program

“From a research perspective, ENDO is all- Professional Development Opportunities 26

Toronto Guide & Tours 36

“As clinical endocrinologists, we need to be Annual Meeting Contributors 41

Peter J Trainer, MD, FRCP

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Does Breast Cancer Start in the Womb?

CUSTOMIZE YOUR ENDO 07 EXPERIENCE.

Page content as of January 20, 2007 – for up-to-date information, visit

through DNA Methylation

Page content as of January 20, 2007 – for up-to-date information, visit

Page content as of January 20, 2007 – for up-to-date information, visit

PRE-CONFERENCE WORKSHOPS & EVENTS ( Friday, June 1 )

11:3 0 A M – 7:00 P M Closing the Loop

Page content as of January 20, 2007 – for up-to-date information, visit

PRE-CONFERENCE WORKSHOPS & EVENTS ( Friday, June 1 )

Page content as of January 20, 2007 – for up-to-date information, visit

BASIC SCIENCE SESSIONS

Symposia New Insights into Phosphate

Page content as of January 20, 2007 – for up-to-date information, visit

BASIC SCIENCE SESSIONS

Page content as of January 20, 2007 – for up-to-date information, visit

BASIC SCIENCE SESSIONS

Receptor Signaling Cross-Talk B Extension of Human Lifespan & 3:4 5 – 5:15 P M

Page content as of January 20, 2007 – for up-to-date information, visit

BASIC SCIENCE SESSIONS

Page content as of January 20, 2007 – for up-to-date information, visit

BASIC SCIENCE SESSIONS

Page content as of January 20, 2007 – for up-to-date information, visit

CLINICAL SCIENCE & PRACTICE SESSIONS

CLINICAL SCIENCE & PRACTICE SESSIONS

Page content as of January 20, 2007 – for up-to-date information, visit

CLINICAL SCIENCE & PRACTICE SESSIONS

CLINICAL SCIENCE & PRACTICE SESSIONS

IGFs & Cancer T Steroid Treatment & What To Do If Endocrine Updates

CLINICAL SCIENCE & PRACTICE SESSIONS

Page content as of January 20, 2007 – for up-to-date information, visit

CLINICAL SCIENCE & PRACTICE SESSIONS

Elias Siraj, Temple Univ Hosp Syndrome Acromegaly

CLINICAL SCIENCE & PRACTICE SESSIONS

Page content as of January 20, 2007 – for up-to-date information, visit

CLINICAL SCIENCE & PRACTICE SESSIONS ORAL & POSTER SESSIONS

Medullary Thyroid Cancer

Page content as of January 20, 2007 – for up-to-date information, visit

Page content as of January 20, 2007 – for up-to-date information, visit

Career Opportunities in Industry: A panel discussion with

Page content as of January 20, 2007 – for up-to-date information, visit

PROFESSIONAL DEVELOPMENT OPPORTUNITIES

Minority Mentoring Reception

Page content as of January 20, 2007 – for up-to-date information, visit

Page content as of January 20, 2007 – for up-to-date information, visit

n\Îä\£xÊ ££\£xÊ 1«`>ÌiÊ

0AGECONTENTASOF*ANUARYnFORUP TO DATEINFORMATIONVISITÊWWWENDO SOCIETYORGENDO

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Saturday, June 2 1_ NAME___________________________________