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Generic Name Classification Dosage Mode of Action Indication Contraindication Adverse Effect Nursing
!  antiinfective; Moderate to Severe Broad-spectrum Parenteral use History of Special Senses: Assessment & Drug
aminoglycoside Infection aminoglycoside restricted to hypersensitivity Ototoxicity Effects

  antibiotic Adult: IV/IM 1.5²2 antibiotic derived treatment of to or toxic (vestibular Ê Lab tests: Perform
mg/kg loading dose from  
serious reaction with disturbances C&S and renal
followed by 3²5  
Action is infections of GI any impaired function prior to
!   mg/kg/d in 2²3 usually respiratory and aminoglycoside hearing) optic first dose and
!   divided bacteriocidal. urinary tracts antibiotic. Safe neuritis. CNS: periodically during

4² CNS bone use during neuromuscular therapy; therapy
!  8 mg preservative skin and soft pregnancy blockade: may begin pending
free q.d. 
1²2 tissue (category C) or skeletal muscle test results.
drops of solution in (including lactation is not weakness Determine creatini
eye q4h up to 2 burns) when established apnea ne clearance and
drops q1h or small other less toxic respiratory serum drug
amount of ointment antimicrobial paralysis (high concentrations at
b.i.d. or t.i.d. agents are doses); frequent intervals
Child: IV/IM 6²7.5 ineffective or are arachnoiditis particularly for
mg/kg/d in 3²4 contraindicated. (intrathecal patients with
divided Has been used use). CV: impaired renal
>R in combination hypotension function infants
 1²2 mg with other or hypertension. (renal immaturity)
preservative free q.d. antibiotics. Also GI: Nausea older adults
Neonate: IV/IM 2.5 used topically vomiting patients receiving
mg/kg q12²24h for primary and transient high doses or
secondary skin increase in AST therapy beyond 10
infections and ALT and serum d patients with
for superficial LDH and fever or extensive
infections of bilirubin; burns
external eye and hepatomegaly edema obesity.
its adnexa. splenomegaly.

A  Samira Mennel Rosefel H. Prof. Ra mond Fernandez

Generic Name Classification Dosage Mode of Action Indication Contraindication Adverse Effect Nursing

 macrolide and Azithromycin binds Azithromycin is X 
   Ëuestion for history
à  ADULTS, to ribosomal Ê Nausea
 antibiotic used for the       of hepatitis, allergies
Azomycin, Azyth, ELDERLY: 500 mg receptor sites of treatment of mild Ê Vomiting to azithromycin or

susceptible to moderate erythromycin.
Geocit, once, them 250 mg organisms. It inhibits  
  Ê Diarrhea
Macromax, infections of upper
 May give tablets
daily for 4 days. protein synthesis. Ê Abdominal pain
Zenith, Zithromax, respiratory tract 
   without regard to
and Zmax CHILDREN >6 and lower    Ê Headache food.
respiratory tract Check for GI
MONTHS: 10 mg/kg Ê Dizziness
infections, discomfort, nausea,
once (maximum uncomplicated Ê Allergic Reaction and vomiting.
500 mg) then 5
skin or skin Determine pattern of
structure  bowel activity ans
mg/kg/day for 4 infections, and stool consistency.
days (maximum 250 sexually Monitor hepatic
transmitted function tests,
mg). diseases. It assess for
prevents hepatotoxicity:
disseminated c  malaise, fever,
abdominal pain, and
complex. GI disturbances.
Evaluate for
genital/anal pruritus,
sore mouth or
tongue, moderate to
severe diarrhea.