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Precipitating Factors:

X. PATHOPHYSIOLOGY  Lifestyle: drinks 10-12 bottles of


Predisposing Factors: alcoholic beverages 3 – 4 times in a week

 Ages 45 – 64  Systemic diseases such as hypertension


(client’s blood pressure is 140/90 mmHg)
 Occurs mostly in male
 Diagnosed of pulmonary tuberculosis on
 Family history of 2007; pulmonary edema on 1993
hypertension

Thickening and/or an increase


Treatment in the amount of collagen in the basement membranes
of the small vessels Kidney
of the
transplantatio
underlyin n
g problem Impaired/sluggish blood flow

Decrease in glomerular
filtration rate (GFR)less than 15%
Increase Increase
d Glomerulosclerosis d
creatinin BUN
e
Remaining nephrons undergo changes to Pathophysiology
compensate for those damaged nephrons
Signs and Symptoms
Filtration of more concentrated blood Treatment
by the remaining nephrons
Break in signs and
Hypertrophy of symptoms
remaining nephrons

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Dehydratio Dilute Hyponatremi
polyuri Inability to Loss of sodium
n concentrate urine in urine a
a

Further loss of Sodium


Dry lips, nephron function Chlorid Dialysi
oral e s
mucosa,
tongue Loss of nonexcretory Loss of excretory
renal function renal function

Disturbances in Immune Increased Impaired insulin Failure to produce Failure to convert inactive
reproduction disturbances production of lipids action erythropoietin forms of calcium

Oral iron Decreased calcium


Advanced Erratic supplement
atherosclerosis blood absorption
glucose
levels Recombinant
human
Antibiotic eryhtropoieti Hypocalcemi
Decrease s; anti- n a
d libido infectives
Osteodystroph
Anemia y
Infectio
Pale
n
punctae,
Infertilit oral mucosa Increased
Decrease
y segmente
d
rs
Decreased RBC
Decrease Hemoglobi
d WBC n

Decreased Decreased
Delaye Hematocrit energy level
d Pale
wound conjunctiva
healing e
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Decreased hydrogen Decreased potassium Decreased excretion of
Decreased phosphate Decreased sodium Potassium
secretion and decreased excretion nitrogenous wastes
excretion reabsorption in tubule chloride
bicarbonate reabsorption
Yellowis
Fluid
h skin
Phosphorus restriction Increase
-binding Hyperkalemia Water retention d
Metaboli agents creatinin
Increase
c Loop e
d uric
acidosis Hyperphosphatemi diuretics acid
a Hypokalemia
Uremia
Sodium
bicarbonat
e Vitami Decreased calcium Increase
Hypertensio
nD absorption Heart d
n
failure BUN Proteinuri
Calcium a
replacemen Hypercalcemi
t a Periphera Pericarditi
l edema Peripheral Lotion s
nerve s
Potassium
changes Bathin
Hyperparathyroidism restriction
g Cardiac
Edema tampona
CNS de
Decreased potassium excretion
Anticonvulsant changes
Potassium Pruritu
binding s s
agents
Heart
Hyperkalemia murmur
Prolonge Bleeding
Ecchymosi s
d tendenci
s
ProTime es

Altere
d taste

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