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Minireview Vol. 279, No. 47, Issue of November 19, pp. 48487–48490, 2004
© 2004 by The American Society for Biochemistry and Molecular Biology, Inc.
Printed in U.S.A.
presence of an immunoreceptor tyrosine-based inhibition motif receptors (21). In addition, CRP has been found to delay the
(ITIM) sequence. Biological responses triggered by ITAM-con- onset and development of experimental allergic encephalomy-
taining Fc␥Rs include phagocytosis, respiratory bursts, and elitis, an aseptic animal model of multiple sclerosis (22). In a
secretion of cytokines. ITIM-containing Fc␥Rs, when found co- murine model of chemotactic factor-induced alveolitis, CRP has